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THE ELDERLY:
   NUTRITIONAL NEEDS,
 CHALLENGES CHALLENGES
SCREENING AND SOLUTIONS
OBJECTIVES

 Describe how the nutritional needs of the elderly
are different from other adult populations
 •Identify several nutritional challenges facing the

elderly and the related healthcare risks
 •Describe the importance of nutritional
  screening
and intervention with individuals at risk
 •List at least two nutrition intervention solutions
  for the elderly
NUTRITION: A KEY COMPONENT OF SUCCESSFUL
AGING AND QUALITY OF LIFE
 Quality of Life
 Family, Caregivers, Community

 Social Interactions, Spirituality, Religion

 Independence, Living Arrangements

 Physical, Mental, Emotional Functioning

 Health Status, Disease Management

 Nutritional Well‐Being
AGE-RELATED CHANGES AND NUTRITION

 Sacropenia, or the loss of lean muscle mass,
 can lead to a gain in body fat that may not be
 apparent by measuring body weight. It may
 be more noticeable by loss of
  strength, functional
 decline, and poor endurance. This loss
 also leads to reduced total body water content.
  Another common loss related
 to aging is changes in bone density, which can
 increase the risk for osteoporosis.
AGE-RELATED CHANGES AND NUTRITION

   Many changes occur throughout the digestive system. A decrease
    in saliva production—xerostomia—and changes in dentition alter
    the ability to chew and may lead to changes in food choices.
   There is a decrease in gastric acid secretion that can limit the
    absorption of iron and vitamin B12.
   Peristalsis is slower and constipation may be an issue because
    fluid intake is decreased.
   Appetite and thirst dysregulation also occur, leading to early
    satiety and a blunted thirst mechanism.
   Sensory changes affect the appetite in several ways. Vision loss
    makes shopping, preparing food, and even eating more difficult.
   Diminished taste and smell take away the appeal of many foods
    and may lead to preparing or consuming food that is no longer
    safe.
AGE-RELATED RENAL IMPAIRMENT


   In addition to gastrointestinal physiological
    changes, renal function declines with age. This
    decreases responsiveness to antidiuretic
    hormone, which often results in an increased
    risk for dehydration in older patients. This
    impaired thirst drive makes it difficult to replete
    fluid losses by oral intake alone. Renal
    impairment may also affect vitamin D
    metabolism and result in a reduction of vitamin
    D levels, which contributes to osteoporosis in
    the elderly.
   A comprehensive geriatric assessment also addresses
    psychosocial, environmental factors, and affective symptoms of
    weight loss in the elderly. The loss of a caregiver, the inability to
    drive a motor vehicle, or moving into a new apartment or
    residence may precipitate a decline in oral intake and cause
    weight loss. Depressive symptoms such as these are important
    considerations when evaluating the nutritional health of a senior
    patient (Hazzard et al 1994; Kane et al 1994; Williams 1995;
    Refai and Seidner 2001). It is especially important to ask older
    patients about alcohol intake, which may replace or suppress the
    consumption of foods with superior nutritional value. Alcohol
    misuse in the elderly is associated with impaired functional
    status, poor self-rated health, and depressive symptoms (St John
    et al 2002).
   Even slight weight loss in the elderly is an independent predictor
    of morbidity and mortality. The medical causes of weight loss may
    be compounded by psychosocial and environmental factors.
PHYSIOLOGY OF AGING AND NUTRITIONAL STATUS


   basal metabolism or energy requirements for
    the elderly diminish by about 100 kcal/day
    per decade. For some seniors it may be
    difficult to meet daily micronutrient
    requirements with this reduced caloric intake.
    To combat this, a multivitamin supplement for
    seniors is recommended , especially for
    those whose caloric intake is less than 1500
    kcal/day .
PHYSIOLOGY OF AGING AND NUTRITIONAL STATUS

   Cardiovascular, pulmonary, and neurological diseases, as
    well as osteoarthritis and osteoporosis, may alter energy
    requirements in the elderly either by increasing energy
    expenditure or reducing requirements through muscle loss
    related to inactivity. Actual energy needs may vary widely
    from calculated energy needs because of these factors. This
    makes the elderly a heterogeneous group and more difficult
    to assess nutritionally. An increase in metabolic
    requirements has not been associated with pressure ulcers
    (an unfortunately common condition in hospitalized elderly
    patients), although frequently concomitant conditions such
    as infection might encourage weight loss in older patients as
    a result of increased energy expenditure, decreased
    albumin, and protein undernutrition
NUTRITIONAL NEEDS OF HEALTHY ADULTS:
  ESTIMATED ENERGY REQUIREMENTS DECLINE
  WITH AGE

              Male         Female

30 years      2080         1762



80 years      1580         1412
NUTRITIONAL NEEDS OF HEALTHY ADULTS:
MACRONUTRIENT DISTRIBUTION TO MEET
ENERGY NEEDS

   A balance of protein, carbohydrate and fat is needed,
   even as calorie (energy) requirements decline with age

                      %of total   average%   70 yrs
                      cal         total      1482
                                  calories
        protein       10-35%      15%        224cals
                                             (56g)
        Carbohydrat   45-65%      52%        772cals
        e                                    (193g)
        fat           20-35%      33%        486cals
                                             (54g)
CURRENT PROTEIN RECOMMENDATION
MAY NOT BE ADEQUATE FOR ELDERLY
  Current RDA(Recommended Dietary Allowance)
for Protein
 – Established for healthy men and women ≥19 yrs

 – 0.8g protein/kg/day

 – 46g/day (female)

 – 56g/day (male)
 Increased Protein Suggested for Elderly
 To help maintain metabolic, physical and
  functional status
 – 1.0 – 1.5g protein/kg/day

 – 58g – 86g/day (female)

 – 70g – 105g/day (male)
WATER INTAKE

 Total Water*(liters/day)
 Male(19-70+): 3.7

 Female(19-70+): 2.7

*Total water includes all water contained in
  food, beverages, and drinking water
TOTAL FIBER (GRAMS/DAY)

 Total Fiber (grams/day)
        19-50 51-70 71+ real intake
 male 38g       30g   30g 17.0g

   female 25g 21g   21g    14.3g
   Increasing dietary fiber may be useful in the
    treatment of constipation, glucose
    intolerance, lipid disorders, and obesity, as
    well as preventing diverticular disease and
    colon cancers. Reduction in sodium has
    been shown to reduce blood pressure and
    also reduce the risk of developing
    hypertension (Patterson 1994).
MICRONUTRIENT REQUIREMENTS FOR OLDER ADULTS
(>50 YEARS)
    Food and Nutrition Board Recommendations (RDAexcept where
    otherwise
    noted) Recommendation Micronutrient Men Women Vitamins
    Biotin 30 mcg/day (AI)30 mcg/day (AI) Folic acid 400
    mcg/day 400        mcg/day       Niacin  16    mgNE*/day     14
    mg NE/day        Pantothenic acid 5 mg/day (AI)5 mg/day
    (AI) Riboflavin 1.3 mg/day1.1 mg/day Thiamin 1.2 mg/day1.1
    mg/day Vitamin A 900 mcg (3,000 IU)/day700 mcg (2,333
    IU)/day Vitamin B6 1.7 mg/day1.5 mg/day Vitamin B12 2.4
    mcg/day#2.4 mcg/day#100-400 mcg/day of crystalline vitamin
    B12Vitamin C 90 mg/day75 mg/day≥ 400 mg/day Vitamin D (51-70
    years) 15 mcg (600 IU)/day15 mcg (600 IU)/day2,000 IU/day from
    supplements Vitamin D (> 70 years) 20 mcg (800 IU)/day20 mcg
    (800 IU)/day2,000 IU/day from supplements Vitamin E 15 mg (22.5
    IU)/day15 mg (22.5 IU)/day200 IU/day supplement of natural-
    source (RRR- or d-) alpha-tocopherol Vitamin K 120 mcg/day
    (AI)90 mcg/day (AI) Minerals
   Calcium (51-70 years) 1,000 mg/day1,200 mg/day Calcium (> 70
    years) 1,200 mg/day1,200 mg/day Chromium 30 mcg/day (AI)20
    mcg/day (AI) Copper 900 mcg/day900 mcg/day Fluoride 4 mg/day
    (AI)3 mg/day (AI) Iodine 150 mcg/day150 mcg/day Iron 8 mg/day8
    mg/dayNo supplement Magnesium 420 mg/day320 mg/dayNo
    supplement providing > 350 mg/day Manganese 2.3 mg/day (AI)1.8
    mg/day (AI) Molybdenum 45 mcg/day45 mcg/day Phosphorus 700
    mg/day700 mg/day Potassium 4.7 g/day (AI)4.7 g/day
    (AI) Selenium 55 mcg/day55 mcg/day Sodium (51-70 years) 1.3
    g/day (AI)1.3 g/day (AI) Sodium (> 70 years) 1.2 g/day (AI)1.2 g/day
    (AI) Zinc 11 mg/day8 mg/day *NE, niacin equivalent: 1 mg NE = 60
    mg        of      tryptophan        =      1        mg        niacin

   #Vitamin B12 intake should be from supplements or fortified foods
    due to the age-related increase in malabsorption
   RDA=Recommended Dietary Allowance; AI=Adequate Intake
VITAMIN D
   generally healthy adults take 2,000 IU (50 mcg) of supplemental
    vitamin D daily. Most multivitamins contain 400 IU of vitamin
    D, and single ingredient vitamin D supplements are available for
    additional supplementation. Sun exposure, diet, skin color, and
    obesity have variable, substantial impact on body vitamin D
    levels. To adjust for individual differences and ensure adequate
    body vitamin D status, aiming for a serum 25-hydroxyvitamin D
    level of at least 80 nmol/L (32 ng/mL). Numerous observational
    studies have found that serum 25-hydroxyvitamin D levels of 80
    nmol/L (32 ng/mL) and above are associated with reduced risk of
    bone fractures, several cancers, multiple sclerosis, and type 1
    (insulin-dependent) diabetes. Daily supplementation with 2,000 IU
    (50 mcg) of vitamin D is especially important for older adults
    because aging is associated with a reduced capacity to
    synthesize vitamin D in the skin upon sun exposure.
CAUSES OF VITAMIN D DEFICIENCY IN
           THE ELDERLY
• habitually low dietary intake (120-200 I.U./d)
• impaired synthesis in senile skin (see below)
• little sun exposure in homebound and institutionalized elderly people




                                                                          21
RECOMMENDATIONS:
     (EXPERT PANEL OF THE NATIONAL OSTEOPOROSIS FOUNDATION, 2003)




     Women under 50 should consume 1200 mg of calcium
      and 600 (800) IU of vitamin D
     Physical activity

     Active strategies to avoid falls

     Avoid falls and the consumption of more than two
      alcoholic drinks per day




22
CALCIUM
   To minimize bone loss, older men (> 70 years)
    and postmenopausal women should consume a
    total (diet plus supplements) of 1,200 mg/day of
    calcium. Men aged 51-70 years should
    consume 1,000 mg of calcium per day. No
    multivitamin/multimineral supplement contains
    the RDA for calcium (1,000-1,200 mg/day)
    because the resulting pill would be too large to
    swallow. If your total daily calcium intake doesn't
    add up to 1,000 mg, It is recommended to take
    an extra calcium supplement (combined with
    magnesium) with a meal.
MAGNESIUM
   Older adults are less likely than younger adults to
    consume enough magnesium to meet their needs and
    should therefore take care to eat magnesium-rich foods in
    addition to taking a multivitamin-mineral supplement daily.
    However, no multivitamin/mineral supplement contains
    100% of the DV for magnesium. If you don’t eat plenty of
    green leafy vegetables, whole grains, and nuts, you likely
    are not getting enough magnesium from your diet. If you
    add a magnesium supplement, It is recommended a
    combined magnesium-calcium supplement containing
    133-250 mg of magnesium and 333-500 mg of calcium
    with a meal. Because older adults are more likely to have
    impaired kidney function, they should avoid taking more
    than 350 mg/day of supplemental magnesium without
    medical consultation
Lack of vitamin B12
       Causes
     - Poor intestinal absorption
     - Decreased binding with intrinsic factor eg:
        - Gastric resection
        - Atrophic gastritis
        - Metabolic disorders
     - Low consumption

       Consequences
       -   Pernicious anemia
       -   Memory loss
       -   Reduced motor coordination
       -   Myopathia

25
Sources of Vitamin B12




26
SODIUM
   There is consistent evidence that diets relatively low in salt (5.8 grams/day or
    less) and high in potassium (at least 4.7 grams/day) are associated with
    decreased risk of high blood pressure and the associated risks of cardiovascular
    and kidney diseases. Diets low in sodium and rich in potassium are likely to be of
    particular benefit for older individuals, who are at increased risk of high blood
    pressure. Moreover, the Dietary Approaches to Stop Hypertension (DASH) trial
    demonstrated that a diet emphasizing fruits, vegetables, whole grains, nuts, and
    low-fat dairy products substantially lowered blood pressure, an effect that was
    enhanced by reducing salt intake to 5.8 grams/day or less. It is recommended
    that a diet that is rich in fruits and vegetables (at least 5 servings/day) and limits
    processed foods that are high in salt. Sensitivity to the blood pressure-raising
    effects of salt increases with age; therefore, consuming diets that are low in salt
    and high in potassium may especially benefit older adults.
   Diets rich in potassium (at least 4.7 grams/day) and low in salt (5.8 grams/day or
    less) are likely to be of particular benefit for older adults, who are at increased
    risk of high blood pressure along with its associated risks of cardiovascular and
    kidney diseases. Since sensitivity to the blood pressure-raising effects of salt
    increases with age, consuming diets that are low in salt and high in potassium
    may especially benefit older adults.
OTHER NUTRIENTS

 Essential Fatty Acids
 L-carnitine

 Flavonoids
ESSENTIAL FATTY ACIDS
   Alpha-linolenic acid (ALA), an omega-3 fatty
    acid, and linoleic acid (LA), an omega-6 fatty
    acid, are considered essential fatty acids
    because they cannot be synthesized by
    humans. In 2002, the Food and Nutrition
    Board of the U.S.Institute of
    Medicine established adequate intake (AI)
    levels for omega-6 and omega-3 fatty acids.
    Essential fatty acid recommendations for
    adults over the age of 50 are listed below.
 Adequate Intake (AI) for Essential Fatty
  Acids Essential Fatty Acid
 ALA (> 50 years) Men 1.6 g/day Women
  1.1 g/day
 LA (> 50 years) Men 14 g/day Women 11
  g/day Abbreviations: ALA=alpha-linolenic
  acid; LA=linoleic acid; g=grams
   American Heart Association
    Recommendation
    The American Heart Association
    recommends that people without documented
    CHD eat a variety of fish (preferably oily) at
    least twice weekly, in addition to consuming
    oils and foods rich in ALA. People with
    documented CHD are advised to consume
    approximately 1 g/day of EPA + DHA
    preferably from oily fish, or to consider EPA +
    DHA supplements in consultation with a
    physician. Patients who need to lower serum
    triglycerides may take 2-4 g/day of EPA +
    DHA supplements under a physician's care.
L-CARNITINE

   Age-related declines in mitochondrial function and increases in
    mitochondrialoxidant production are thought to be important
    contributors to the adverse effects of aging. Tissue L-carnitine
    levels have been found to decline with age in humans and
    animals . One study found that feeding aged rats acetyl-L-carnitine
    (ALCAR) reversed the age-related declines in tissue L-carnitine
    levels and also reversed a number of age-related changes in liver
    mitochondrial function; however, high doses of ALCAR increased
    liver mitochondrial oxidant production . More recently, two studies
    found that supplementing aged rats with either ALCAR or alpha-
    lipoic acid, a mitochondrial cofactor and antioxidant, improved
    mitochondrial energy metabolism, decreased oxidative stress, and
    improved memory . Interestingly, co-supplementation of ALCAR
    and alpha-lipoic acid resulted in even greater improvements than
    either compound administered alone
L-CARNITINE
   Age-related declines in mitochondrial function and increases in
    mitochondrialoxidant production are thought to be important
    contributors to the adverse effects of aging. Tissue L-carnitine
    levels have been found to decline with age in humans and
    animals . One study found that feeding aged rats acetyl-L-
    carnitine (ALCAR) reversed the age-related declines in tissue L-
    carnitine levels and also reversed a number of age-related
    changes in liver mitochondrial function; however, high doses of
    ALCAR increased liver mitochondrial oxidant production . More
    recently, two studies found that supplementing aged rats with
    either      ALCAR         or      alpha-lipoic      acid,      a
    mitochondrial cofactor and antioxidant, improved mitochondrial
    energy metabolism, decreased oxidative stress, and improved
    memory . Interestingly, co-supplementation of ALCAR and alpha-
    lipoic acid resulted in even greater improvements than either
    compound administered alone.
FLAVONOIDS
   Because flavonoids have anti-
    inflammatory, antioxidant and metal-chelating
    properties, scientists are interested in the
    neuroprotective potential of flavonoid-rich diets or
    individual flavonoids. At present, the extent to which
    various dietary flavonoids and
    flavonoid metabolites cross the blood-brain barrier in
    humans is not known. Although flavonoid-rich diets
    and flavonoid administration have been found to
    prevent cognitive impairment associated with aging
    and inflammation in some animal studies, prospective
    cohort studies have not found consistent inverse
    associations between flavonoid intake and the risk
    of dementia or neurodegenerative disease in humans
DIETARY RECOMMENDATIONS

   Following careful nutritional assessment, guidelines have
    been developed to improve and maintain nutritional status
    in community-dwelling and hospitalized elderly patients.
    For example, the Canada Food Guide recommends the
    following daily nutritional intake for adults:
   5â€―12 servings of grains
   5â€―10 servings of fruits and vegetables
   2â€―4 servings of milk products
   2â€―3 servings of meat or meat alternatives
   Foods high in fibre and complex carbohydrates such as
    whole grains, vegetables, and fruits are preferred. Fat
    intake should be less than 30% of total caloric intake
A food pyramid for the elderly

       Sweets and fats in moderation           Calcium, vitamin D, vitamin B12,
                                               Wholemeal




     Milk, yogurt, cheese                                 Fish meat legumes
     3 portions                                           2 portions


      Vegetables                                               Fruit 2 portions
      3 portions


     Wholemeal                                                      Cereals and tubers
     is better                                                      6 portions



36
                            Water and liquids 8 glasses
EFFECTS OF AGING ON NUTRITION
   Changes Effects
   Sensory Impairment
   –Decreased sense of taste ÎReduced Appetite
   –Decreased sense of smell ÎReduced Appetite
   –Loss of vision and hearing ÎDecreased ability to purchase and
    prepare food
   –Oral health / dental problems ÎDifficulty
    chewing, inflammation, poor quality diet
   Altered energy need ÎDiet lacking in essential nutrients
   Decreased physical activity ÎProgressive depletion of LBW and
    loss of appetite
   Muscle loss (sarcopenia) ÎDecreased functional ability, assistance
    needed with ADLs.
ASSESSING NUTRITIONAL STATUS

   A comprehensive assessment of nutritional status
    includes anthropometric measurements,
   laboratory values, physical exam, and patient history.
    Anthropometric measures include
   height, weight, body mass index, body fat
    measurement, muscle mass measurement, and
   body mass index. Laboratory values should include
    albumin, retinal-binding
    prealbumin, transferring, complete blood count, serum
    folate, vitamin B12, and cholesterol. A diet history is
    helpful if there is good 24-hour recall
   or a food record for 3 days leading up to the exam can be
    completed.
   the Mini Nutritional Assessment is a basic screening tool.
PREVALENCE OF MALNUTRITION IN THE
ELDERLY

                Malnurished   At risk   Normally
                                        nourished
Nursing home    14%           53%       33%

Hospitalized    39%           47%       14%

Rehablitation   50%           41%       9%

Community       6%            32%       62%
PREVALENCE OF MANUTRITION IN THE ELDERLY

 1 of 4 of older adults are malnourished.
 2 of 4 of older adults are risk of malnutrition.
POSSIBLE CAUSES OF UNINTENTIONAL WEIGHT LOSS:

   M Medications
   E Emotional Problems
   A Anorexia Nervosa
   L Late‐life Paranoia
   S Swallowing Problems
   Oral Factors (cavities poorly fitting dentures)
   N No Money
   W Wandering and Other Dementia Related
   Behaviors
   H Hyperthyroidism, Hypothyroidism
   E Enteric Problems (malabsorption)
   E Eating Problems (inability to feed self)
   L Low Salt, Low Cholesterol Diets
   S Shopping, Social Problems
WEIGHT LOSS
   Weight loss in the elderly is a worrisome clinical sign.
    Weight loss in the elderly due to voluntary or involuntary
    causes has been associated with mortality (Himes
    1999; Newman et al 2001; Baldwin et al 2002). Although
    lean body mass may decline because of normal
    physiological changes associated with age (Lissner et al
    1991), a loss of more than 4% per year is an independent
    predictor of mortality (Wallace et al 1995). Rapid weight
    loss of 5% or more in one month is considered significant
    and needs to be immediately evaluated by a physician
    (Jensen et al 2001; Dryden et al 2002). It has been shown
    that even moderate declines of 5% or more over three
    years is predictive of mortality in older adults (Newman et
    al 2001). However, early identification, assessment, and
    treatment of weight loss and nutritional deficiencies may
    prevent the morbid sequel of malnutrition.
WEIGHT LOSS
   Functional, psychological, social, and economic issues
    associated with concomitant medical problems may all
    contribute to poor nutrition and weight loss in the frail
    elderly patient (Bartali et al 2003). A multidisciplinary
    geriatric assessment can be helpful to fully address all the
    complex interacting issues of the frail senior, such as Mrs
    E, who experiences rapid weight loss as a result of
    malnutrition. This type of comprehensive assessment
    may           include         the         services         of
    physicians, nurses, dieticians, occupational and physical
    therapists, speech and language pathologists, and social
    workers, each of which can lend their respective expertise
    to       the       effective       diagnosis     of      the
    functional, psychological, and socioeconomic contributors
    to malnutrition in older patients.
AGEING AND OBESITY

1.   Cardiac disease
2.   Tumours
3.   Cerebrovascular diseases
4.   Chronic pulmonary disease
5.   Diabetes mellitus
NUTRITIONAL ISSUES ASSOCIATED WITH COGNITIVE
IMPAIRMENT AND VASCULAR RISK FACTORS

   Malnutrition has been associated with compromised
    cognitive capacity in the elderly. The decreased
    ability to prepare a meal, which may adversely affect
    an elderly patient's ability to ensure sufficient
    nourishment, has been cited as one of the earliest
    signs of mild cognitive impairment (MCI), a pre-
    Alzheimer disease condition (Borrie et al 2003). For
    persons with moderate to severe Alzheimer
    disease, forgetting to eat, inability to access food, and
    apraxia with utensils may further impair oral intake.
    Living alone, as Mrs E does, further compounds the
    risk of malnutrition.
NUTRITIONAL ISSUES ASSOCIATED WITH COGNITIVE
    IMPAIRMENT AND VASCULAR RISK FACTORS
   Vitamin deficiencies, particularly vitamin B12, B6, and
    folate, are associated with cognitive impairment (Nilsson
    et al 2001; Gill and Alibhai 2003; Lehmann et al 2003).
    Deficiencies in these vitamins are also associated with
    hyperhomocysteinemia, which is an independent vascular
    risk factor. The association of hyperhomocysteinemia
    with vascular disease is a direct dose-response
    association (Stamphler et al 1992;Selhub et al 1995).
    Treatment with folate, vitamin B6, and vitamin B12 has
    been shown to reduce homocysteine levels (Omran and
    Morley 2000; Nillson et al 2001; Lehmann et al 2003; Scott
    et    al    2004),   improve     vascular   function    in
    hyperhomocysteinemic patients with coronary artery
    disease (Willems et al 2002), and result in cholesterol
    plaque regression (Marcucci et al 2003
   Although a recent secondary prevention randomized
    controlled trial failed to demonstrate a decrease in morbid
    vascular      outcomes       in     stroke    patients   following
    supplementation with vitamins B6, B12, and folate over two
    years, it was suggested that confounding factors (such as
    the initiation of folate fortification in grain supply concurrent
    with the study) might explain the null findings (Toole et al
    2004). More research is needed to clarify the complex
    interactions between these vitamins and the modification of
    vascular risk factors.
   Nutritional interventions have an impact on vascular
    disease prevention. It is well established that a diet
    low in fat and cholesterol is beneficial to modifying
    vascular risk factors. Emerging research suggests
    that supplementation with omega-3 fatty acids (such
    as those found in salmon and other cold-water
    fish), and consuming cruciferous vegetables (such
    as broccoli, cabbage, and cauliflower) are all
    associated with stroke prevention (Joshipura et al
    1999; Mozaffarian et al 2005; Robinson and
    Maheshwari 2005) and may be beneficial if
    integrated into the diet of all elderly patients with
    vascular disease or vascular risk factors.
   Nutritional antioxidant supplements are generally believed
    to be beneficial in reducing free radical cellular and DNA
    damage. A large epidemiological study found the
    concomitant use of vitamins C and E is associated with
    reduced incidences of Alzheimer disease (Zandi et al
    2004). More generally, according to a randomized
    controlled trial, low blood vitamin C concentrations are
    strongly predictive of mortality in patients aged 75â€―84
    years (Fletcher et al 2003). The efficacy of vitamin E in the
    prevention and treatment of MCI and Alzheimer disease
    remains controversial. Used alone in a three-year placebo-
    controlled study, a daily dosage of vitamin E (2000 IU) was
    not shown to slow the rate of progression to Alzheimer
    disease in patients with MCI (Petersen et al 2005). A high-
    dose vitamin E supplementation (>400 IU/day) has been
    associated with increased mortality (Miller et al 2005).
   Other important antioxidants with possibly
    beneficial outcomes include foods with high
    levels of phytochemicals and flavonoids.
    Tomatoes, citrus fruit, blueberries, and certain
    spices (Fusheng et al 2005) have all been
    linked to reducing oxidative stress and
    cognitive     impairment.    Flavonoids     and
    antioxidants in red wine have also been
    shown to be beneficial in protecting against
    dementia (Zuccalà et al 2001; Truelson et al
    2002). The increasing amount of research in
    this field holds promise for preventive
    nutritional strategies based on the benefits of
    naturally-occurring antioxidants.
ANTIOXIDANT FOOD WHEEL
                                                                       OLIVE OIL
                                                           NUTS AND
                                                             DRIED
A good diet should contain                                   FRUIT
                                           PULSEs
antioxidants: vitamin C, vitamin
E, polyphenols.                                                                    FRUIT




Vitamin C and E make your
immune system more efficient       COCOA

(de la Fuente et al. 1998).


―We age because we oxidise
(rust)‖ and anti-oxidants can
mitigate the signs of ageing               BREAD CEREALS
                                            AND POTATOES

(Miquel et al. 2002).                                                 VEGETABLES




                                              S.E.N.E. C.A.
51                                                2007
POTENTIAL CONSEQUENCES OF MALNUTRITION

   Impaired immune response
    Reduced muscle strength and fatigue
   Inactivity
    Impaired temperature regulation
    Impaired wound healing
    Impaired ability to regulate fluid and
    electrolytes
    Impaired psycho‐social function
DIET AS ENERGY
      The diet should be the source of energy for all daily
       activities.

      Breakfast or lunch should be the highest-energy
       meals of the day, in order to complete the most
       important activities.

      Dinner should be the least energetic meal of the
       day, because few activities are done after dinner.

      Meals (breakfast in particular) should not be skipped.

      The diet should provide calories according to the
       needs of each individual.
53
How many calories
                after the age of 50?

     WOMEN
     LITTLE PHYSICAL ACTIVITY: 1.600 CALORIES
     MODERATE PHYSICAL ACTIVITY: 1,800 CALORIES
     ACTIVE LIFESTYLE: 2,000-2,200 CALORIES

     MEN
     LITTLE PHYSICAL ACTIVITY : 2.000 CALORIES
     MODERATE PHYSICAL ACTIVITY : 2.200-2.400 CALORIES
     ACTIVE LIFESTYLE : 2,400-2,800 CALORIES




54
FOODS RECOMMENDED AS A SOURCE OF
         EACH NUTRIENT

     PROTEIN: meat, fish, eggs, milk products, pulses
     (chickpeas, lentils).

     CARBOHYDRATES: bread, rice, pasta, potatoes, pulses.

     FATS: olive oil, oily fish, nuts, dried fruit.

     VITAMINS: fruit and vegetables, olive oil.

     MINERALS: milk products, nuts and dried fruits, fish,
     cereals.

55   FIBRE: fruit, vegetables, wholemeal products.
Cereals and tubers
 CEREALS: RICE, BREAD, PASTA, CORN, WHEAT, BARLEY, SPELT
 AND TUBERS (EG. POTATOES) ARE THE PRINCIPAL SOURCE OF
 ENERGY.

 IT IS ADVISEABLE TO USE, AT LEAST SOMETIMES, WHOLEMEAL
 PRODUCTS. THESE CONTAIN PROTEIN AS WELL, AND ARE
 RICHER IN MINERALS AND VITAMINS.

 AMOUNT PER DAY: 6 PORTIONS
 ONE PORTION, FOR EXAMPLE: HALF A PLATE OF PASTA OR
 RICE, A SANDWICH, A BOWL OF CEREAL



56
Fruit and vegetables

 FRUIT AND VEGETABLES CONTAIN VITAMINS, FIBRE AND WATER
 AND MINERAL SALTS.
 ALIMENTARY FIBRE HELPS YOU TO FEEL MORE FULL AND
 REDUCE THE RISK OF TUMOURS, DIABETES, AND HEART
 DISEASE.

 CHOOSE FRESH SEASONAL OR FROZEN VEGETABLES.
 IT IS BEST TO STEAM THEM OR COOK THEM IN A PRESSURE
 COOKER WITH VERY LITTLE WATER.

 DAILY AMOUNT:
 3 PORTIONS OF VEGETABLES
 2 PORTIONS OF FRUIT
57
Meat, fish and eggs
     THESE ARE FOODS RICH IN PROTEIN WITH A HIGH
     BIOLOGICAL VALUE, WITH MINERALS AND B VITAMINS.

     LEAN MEAT AND FISH ARE PREFERABLE.

     IT IS BEST TO GRILL THEM, STEAM THEM, OR COOK THEM
     WITH VERY LITTLE FAT

     DAILY AMOUNT:
     2 PORTIONS



58
Milk, yogurt and cheese

 MILK AND MILK PRODUCTS (CHEESE, YOGURT) PROVIDE
 CALCIUM, PROTEIN AND SOME VITAMINS.

 IT IS ADVISABLE TO USE, AT LEAST PARLY SKIMMED, LOW-FAT
 PRODUCTS.

 DAILY AMOUNTS:
 3 PORTIONS

 ONE PORTION, FOR EXAMPLE: 50G OF CHEESE, A GLASS OF
 MILK OR 1 YOGHURT (100 GR)


59
Limit animal fats
 CHOOSE LEAN MEATS, FISH OR POULTRY (WITHOUT THE SKIN)

 REMOVE THE FATTY PARTS BEFORE COOKING

 USE LOW-FAT PRODUCTS

 USE LITTLE FAT FOR COOKING

 CHOOSE VEGETABLE FATS (EXTRA VIRGIN OLIVE OIL)

 AVOID FRIED FOOD



60
HYDRATION


 Water does not give energy,         but   is
  fundamental for hydration.

 Sugar-free fruit juice, milk and soups can
  also help with hydration.

 The daily dose of liquids should be 1 and a
  half or two litres.

 Fruit and vegetables are a good source of
61
  water.
VARIETY AND BALANCE: THE KEY TO A GOOD
 DIET




At every meal:
protein, carbohydrates, fats, vitam
ins, liquids and fibre in adequate
proportions.




 62
KEY POINTS


•        Avoid chilled, pre-cooked or re-heated meals
•        Break our food down into three meals and two snacks.
•        Have a good breakfast with milk or yogurt.
•        Choose food according to the action necessary to eat it
         (cut, grind, squash, etc).
•        Keep to a good body weight and a good level of physical
         activity.
•        Drink water frequently during the day.
•        Chew each mouthful well before swallowing.


    63
Key Points (2)
    Tasty and varied food with aromatic herbs and spices
    Avoid the consumption of animal fats
    Eat more fish (especially oily fish)
    Eat more food rich in complex carbohydrates, fibre, vitamins
     and minerals (fruit, vegetables, pulses and wholemeal
     products)
    Sugar: is obtained from fruit and milk
    Wine: in moderation (1-2 glasse per day); avoid spirits
    Salt: limit what you add at the table




64
PRACTICAL ACTIVITIES

Divide participants into 3 groups:

Each participant fills in his or her food diary

They swap diaries with others in the group and analyse the
diaries, classifying 3 of their choices as healthy, and 3 as
unhealthy.

Among all the group members the most interesting case is
selected to be discussed in the plenary.




65
MY DAILY FOOD HABITS
     TIME   6   8   10   1   1   1   2   2   2
                         2   6   8   0   2   4




66
SELECTION
Write in the two columns:




                                            UNHEALTHY FOOD
        HEALTHY FOOD HABITS
                                                HABITS


                            Write at least four items




67
CASE 1

   Mrs E is a 79-year-old female with
    Alzheimer-type dementia living alone in her
    own home with assistance only for heavy
    housework. She has maintained her weight
    for one year while taking a cholinesterase
    inhibitor. She sees her family doctor every 6
    months. Her most recent check-up revealed
    a weight reduction of 3 kg from her previous
    visit. Patient height 160 cm; weight 48 kg
    [BMI=19 kg/m2].
   Mrs E has lost 6% of her body weight in six months. This is a cause for
    concern. Her physician needs to consider causes for weight loss such as new
    hyperthyroidism, diabetes, malignancy, depression, or oral problems. These can
    be ruled out by history, physical examination, and laboratory tests. Collateral
    history from family or caregivers is very important in assessing a person with
    dementia. Patients with dementia often have an atypical presentation of many
    illnesses in the elderly, especially in cases of depression.
   A medication review is also an important part of the physician's assessment of
    this patient. For example, cholinesterase inhibitors as a class can cause
    nausea, vomiting, anorexia, or diarrhea and can be associated with weight loss.
    In Mrs E's case, she was able to maintain her weight for a year on this
    medication. For this reason, other causes of weight loss associated with
    dementia should also be considered. For example, the loss of caregiver
    support, social isolation, limited access to food, an inability to cook and prepare
    food because of cognitive problems, or inability to recognize hunger may
    contribute to her current malnutritive state. Collateral history from a caregiver
    and a home visit can provide invaluable insight into these issues. Home care
    nurses or occupational therapists can assist in this assessment.
   A nutritional treatment plan for Mrs E may include the treatment of any newly
    diagnosed medical issues and the prescription of nutritional supplements. In
    this case, considering a referral to social and community programs (such as
    adult day care, home care services, or a delivered meal program) would be
    appropriate at Mrs E's discharge.
CASE 2

   Mrs A is an 82-year-old female living alone, independent
    in her activities of daily living, and instrumental activities
    of daily living2. She has a history of non-insulin-
    dependent            diabetes        mellitus       requiring
    insulin, hypothyroidism, osteoarthritis, hypertension
    (HTN), ischemic heart disease (IHD), obesity, and
    gastroesophageal reflux disorder (GERD). Mrs E
    recently suffered a hip fracture following a fall for which
    she underwent a hip-replacement surgery. Her
    postoperative course is complicated by a urinary tract
    infection (UTI) and two episodes of clostridium
    difficile (C. difficile) colitis. She was transferred to a
    geriatric rehabilitation unit. Patient height 160 cm; weight
    94 kg [BMI = 37 kg/m2].
   Mrs A's situation is complex and highlights some of the issues of nutritional assessments in the hospital
    setting. A physician is needed to immediately address Mrs A's other underlying medical problems such as
    obesity, IHD, GERD, and HTN, prior to her general nutritional assessment by a dietician. Diabetes can be
    a major issue during her hospital stay. Another possible nutritional issue associated with diabetes is
    substantial proteinuria brought on by diabetic renal disease. Sequelae of diabetes include autonomic
    dysfunction, which can result in delayed gastric emptying and poor oral intake. This condition can be
    exacerbated by the use of narcotics to control postoperative pain, and is further compounded by GERD.
    Infection and obesity often increase insulin resistance, so blood sugar control should be optimized not
    only for the long-term morbidity prevention, but also for wound healing.
   Prior medical complications and the medications prescribed following her hip surgery are another cause
    for concern. Mrs A may have had poor oral intake because of her diarrheal illness, or from the side effects
    of antibiotics used to treat C. difficile arising from her UTI. Many elderly hip fracture patients have muscle
    deconditioning as a result of being hospitalized and consequently require increased protein
    supplementation. Serum prealbumin or albumin is usually used to assess nutritional status and monitor
    improvement through a hospital stay. Although Mrs A is obese with a BMI of 37 kg/m2, she likely has a low
    albumin level and significant protein undernutrition based on her recent medical history. One complication
    in the treatment of obese patients is the provision of adequate calories and protein for wound prevention
    and treatment, muscle reconditioning, and therapy-related exercise while concurrently promoting a loss of
    total body fat. Generally speaking, achieving an optimal balance of food intake, nutritional status, and
    healthy body weight is a particular challenge for health practitioners (Sullivan et al 2004), particularly
    when treating patients with extremely high or low BMI measurements.
   Finally, Mrs A's HTN and obesity suggest additional risk factors for ischemic heart disease. Her
    cholesterol profile prior to her hospitalization would provide additional information in planning long-term
    nutritional goals at discharge. Sodium, fat, and cholesterol restrictions may be appropriate. Other
    nutritional goals during Mrs A's hospital stay should include ensuring that she has adequate education to
    both understand and follow her dietary advice. Referral to a community dietician or diabetic educator is
    recommended in Mrs A's discharge planning.
CASE 3

   Mr T is an 83-year-old male who has been
    living in a nursing home for the past 12
    months since suffering a right middle
    cerebral artery stroke. During this time he
    has had trouble feeding himself and has lost
    10 kg. He has a coccyx ulcer. Patient height
    180 cm; weight 55 kg [BMI= 17 kg/m2].
   Mr T has severe malnutrition with a BMI of 17 kg/m2 and a corresponding high risk
    of morbidity and mortality. Given his acute nutritive needs following his medical
    history of stroke (Dennis et al 2005), Mr T's nutritional assessment and treatment
    plan should include a physician, dietician, speech and language pathologist, and an
    occupational therapist.
   The benefits of stroke rehabilitation are well documented (Gresham et al 1997).
    One of the first treatments often recommended immediately following a stroke is a
    swallowing assessment and, if necessary, training to facilitate improved swallowing.
    For patients who require tube feeding, it has been determined that patients with
    significant dysphagia who undergo gastronomy tube feeding have less risk of
    aspiration, earlier discharge from hospital, and higher albumen levels with
    gastrostomy tube feeding than those who undergo nasogastric tube feeding (Milne
    et al 2005). Early tube feeding following stroke has been associated with decreased
    mortality in older patients (Dennis et al 2005).
   It is likely that Mr T had the appropriate assessment in hospital following his stroke.
    Nevertheless, a bedside swallowing assessment performed by a speech and
    language pathologist is very helpful in determining the type of food consistency that
    is appropriate in a person with dysphagia. Sometimes it is necessary to refer the
    patient for a modified barium swallow to further assess their risk for aspiration.
    Furthermore, positioning and seating are important requirements for successful
    meals. Occupational therapists can assist with this as well as the provision of
    special utensils, plates, or placemats in order to better facilitate self-feeding.
   A number of other possibilities may contribute to Mr T's current condition. For
    example, Mr T may have extended his stroke resulting in worse dysphagia and
    subsequently decreased oral intake. Untreated dysphagia may result in protein
    undernutrition, which can result in compromised immunity and an increased risk
    of infection (Hudson et al 2000). He may have developed post-stroke
    depression, which often manifests a decrease in appetite. It is possible that not
    all of the dietary recommendations of the stroke team were followed after
    discharge. Sometimes this is because of patient choice; for example, a common
    recommendation involves restricting patients' diet to pureed foods. Some
    patients assess the relative risks (which include aspiration) and prefer a diet with
    varied textures as a quality of life consideration. Nutritional deficiencies have
    been suggested, but not clinically confirmed, to adversely affect vascular
    outcomes in stroke (Toole et al 2004).
   Mr T needs a comprehensive physical and cognitive examination, and laboratory
    tests to exclude new medical problems as contributing causes for his weight
    loss. Since protein undernutrition and low vitamin C levels are associated with
    poor wound healing and pressure sores, a dietician should participate in Mr T's
    treatment plan and consider supplementation in vitamin C, zinc, and other trace
    minerals, in addition to increased caloric and protein intake. His albumin level
    should be regularly measured to provide objective monitoring of the treatment
    plan.

KEY POINTS

 Age-related changes in physiology and
  immunity may result in a greater need for
  vitamin and mineral supplementation in the
  elderly.
 Dietary modifications, such as including
  foods high in antioxidants and lowering
  intake of fat and cholesterol, may improve
  cognition and modify vascular risk factors in
  elderly patients.
KEY POINTS

 Hospitalized elderly patients are at particular
  risk for malnutrition and need to be carefully
  assessed and aggressively treated.
 There are several effective and easy-to-use
  screening tools which assess for malnutrition in
  elderly patients. The most extensively validated
  tool is the Mini Nutritional Assessment
  (MNA), which provides an accurate assessment
  of elderly patients from a variety of domiciliary
  settings.
KEY POINTS

   Dietary assessment and counseling
    comprise an important and effective aspect
    of preventing and treating a variety of morbid
    conditions in elderly patients.
TAKE HOME MESSAGE
   Multivitamin supplements are highly recommended for older
    patients, especially in seniors whose daily caloric intake is less than
    1500 kcal/day.
   Advise patients about nutrient-dense food choices when appropriate.
   Investigate body weight losses of 4% or more.
   Nutritional supplements are recommended for at-risk elderly hip fracture
    patients. Also consider supplements for frail seniors with other fractures.
   Calcium and vitamin D supplementation have been shown to reduce hip
    fracture rates and are recommended for patients over 65 years of age.
   Advise patients on the merits of whole grains, fruits, and vegetables.
   In hospitalized patients, maintain a high index of suspicion for pre-
    existing nutritional deficiencies. Utilize the services of a registered
    dietician.
   Consider referrals to other health professionals for nutritional advice
    such as dieticians, speech and language pathologists, homecare or
    visiting nurse services, or other specialized geriatric services available in
    the community.

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Elderly nutrition

  • 1.
  • 2. THE ELDERLY: NUTRITIONAL NEEDS, CHALLENGES CHALLENGES SCREENING AND SOLUTIONS
  • 3. OBJECTIVES  Describe how the nutritional needs of the elderly are different from other adult populations  •Identify several nutritional challenges facing the elderly and the related healthcare risks  •Describe the importance of nutritional screening and intervention with individuals at risk  •List at least two nutrition intervention solutions for the elderly
  • 4. NUTRITION: A KEY COMPONENT OF SUCCESSFUL AGING AND QUALITY OF LIFE  Quality of Life  Family, Caregivers, Community  Social Interactions, Spirituality, Religion  Independence, Living Arrangements  Physical, Mental, Emotional Functioning  Health Status, Disease Management  Nutritional Well‐Being
  • 5. AGE-RELATED CHANGES AND NUTRITION  Sacropenia, or the loss of lean muscle mass,  can lead to a gain in body fat that may not be  apparent by measuring body weight. It may  be more noticeable by loss of strength, functional  decline, and poor endurance. This loss  also leads to reduced total body water content. Another common loss related  to aging is changes in bone density, which can  increase the risk for osteoporosis.
  • 6. AGE-RELATED CHANGES AND NUTRITION  Many changes occur throughout the digestive system. A decrease in saliva production—xerostomia—and changes in dentition alter the ability to chew and may lead to changes in food choices.  There is a decrease in gastric acid secretion that can limit the absorption of iron and vitamin B12.  Peristalsis is slower and constipation may be an issue because fluid intake is decreased.  Appetite and thirst dysregulation also occur, leading to early satiety and a blunted thirst mechanism.  Sensory changes affect the appetite in several ways. Vision loss makes shopping, preparing food, and even eating more difficult.  Diminished taste and smell take away the appeal of many foods and may lead to preparing or consuming food that is no longer safe.
  • 7. AGE-RELATED RENAL IMPAIRMENT  In addition to gastrointestinal physiological changes, renal function declines with age. This decreases responsiveness to antidiuretic hormone, which often results in an increased risk for dehydration in older patients. This impaired thirst drive makes it difficult to replete fluid losses by oral intake alone. Renal impairment may also affect vitamin D metabolism and result in a reduction of vitamin D levels, which contributes to osteoporosis in the elderly.
  • 8. A comprehensive geriatric assessment also addresses psychosocial, environmental factors, and affective symptoms of weight loss in the elderly. The loss of a caregiver, the inability to drive a motor vehicle, or moving into a new apartment or residence may precipitate a decline in oral intake and cause weight loss. Depressive symptoms such as these are important considerations when evaluating the nutritional health of a senior patient (Hazzard et al 1994; Kane et al 1994; Williams 1995; Refai and Seidner 2001). It is especially important to ask older patients about alcohol intake, which may replace or suppress the consumption of foods with superior nutritional value. Alcohol misuse in the elderly is associated with impaired functional status, poor self-rated health, and depressive symptoms (St John et al 2002).  Even slight weight loss in the elderly is an independent predictor of morbidity and mortality. The medical causes of weight loss may be compounded by psychosocial and environmental factors.
  • 9. PHYSIOLOGY OF AGING AND NUTRITIONAL STATUS  basal metabolism or energy requirements for the elderly diminish by about 100 kcal/day per decade. For some seniors it may be difficult to meet daily micronutrient requirements with this reduced caloric intake. To combat this, a multivitamin supplement for seniors is recommended , especially for those whose caloric intake is less than 1500 kcal/day .
  • 10. PHYSIOLOGY OF AGING AND NUTRITIONAL STATUS  Cardiovascular, pulmonary, and neurological diseases, as well as osteoarthritis and osteoporosis, may alter energy requirements in the elderly either by increasing energy expenditure or reducing requirements through muscle loss related to inactivity. Actual energy needs may vary widely from calculated energy needs because of these factors. This makes the elderly a heterogeneous group and more difficult to assess nutritionally. An increase in metabolic requirements has not been associated with pressure ulcers (an unfortunately common condition in hospitalized elderly patients), although frequently concomitant conditions such as infection might encourage weight loss in older patients as a result of increased energy expenditure, decreased albumin, and protein undernutrition
  • 11. NUTRITIONAL NEEDS OF HEALTHY ADULTS: ESTIMATED ENERGY REQUIREMENTS DECLINE WITH AGE Male Female 30 years 2080 1762 80 years 1580 1412
  • 12. NUTRITIONAL NEEDS OF HEALTHY ADULTS: MACRONUTRIENT DISTRIBUTION TO MEET ENERGY NEEDS  A balance of protein, carbohydrate and fat is needed,  even as calorie (energy) requirements decline with age %of total average% 70 yrs cal total 1482 calories protein 10-35% 15% 224cals (56g) Carbohydrat 45-65% 52% 772cals e (193g) fat 20-35% 33% 486cals (54g)
  • 13. CURRENT PROTEIN RECOMMENDATION MAY NOT BE ADEQUATE FOR ELDERLY  Current RDA(Recommended Dietary Allowance) for Protein  – Established for healthy men and women ≥19 yrs  – 0.8g protein/kg/day  – 46g/day (female)  – 56g/day (male)
  • 14.  Increased Protein Suggested for Elderly  To help maintain metabolic, physical and functional status  – 1.0 – 1.5g protein/kg/day  – 58g – 86g/day (female)  – 70g – 105g/day (male)
  • 15. WATER INTAKE  Total Water*(liters/day)  Male(19-70+): 3.7  Female(19-70+): 2.7 *Total water includes all water contained in food, beverages, and drinking water
  • 16. TOTAL FIBER (GRAMS/DAY)  Total Fiber (grams/day)  19-50 51-70 71+ real intake  male 38g 30g 30g 17.0g  female 25g 21g 21g 14.3g
  • 17. Increasing dietary fiber may be useful in the treatment of constipation, glucose intolerance, lipid disorders, and obesity, as well as preventing diverticular disease and colon cancers. Reduction in sodium has been shown to reduce blood pressure and also reduce the risk of developing hypertension (Patterson 1994).
  • 18. MICRONUTRIENT REQUIREMENTS FOR OLDER ADULTS (>50 YEARS)  Food and Nutrition Board Recommendations (RDAexcept where otherwise noted) Recommendation Micronutrient Men Women Vitamins Biotin 30 mcg/day (AI)30 mcg/day (AI) Folic acid 400 mcg/day 400 mcg/day Niacin 16 mgNE*/day 14 mg NE/day Pantothenic acid 5 mg/day (AI)5 mg/day (AI) Riboflavin 1.3 mg/day1.1 mg/day Thiamin 1.2 mg/day1.1 mg/day Vitamin A 900 mcg (3,000 IU)/day700 mcg (2,333 IU)/day Vitamin B6 1.7 mg/day1.5 mg/day Vitamin B12 2.4 mcg/day#2.4 mcg/day#100-400 mcg/day of crystalline vitamin B12Vitamin C 90 mg/day75 mg/day≥ 400 mg/day Vitamin D (51-70 years) 15 mcg (600 IU)/day15 mcg (600 IU)/day2,000 IU/day from supplements Vitamin D (> 70 years) 20 mcg (800 IU)/day20 mcg (800 IU)/day2,000 IU/day from supplements Vitamin E 15 mg (22.5 IU)/day15 mg (22.5 IU)/day200 IU/day supplement of natural- source (RRR- or d-) alpha-tocopherol Vitamin K 120 mcg/day (AI)90 mcg/day (AI) Minerals
  • 19. Calcium (51-70 years) 1,000 mg/day1,200 mg/day Calcium (> 70 years) 1,200 mg/day1,200 mg/day Chromium 30 mcg/day (AI)20 mcg/day (AI) Copper 900 mcg/day900 mcg/day Fluoride 4 mg/day (AI)3 mg/day (AI) Iodine 150 mcg/day150 mcg/day Iron 8 mg/day8 mg/dayNo supplement Magnesium 420 mg/day320 mg/dayNo supplement providing > 350 mg/day Manganese 2.3 mg/day (AI)1.8 mg/day (AI) Molybdenum 45 mcg/day45 mcg/day Phosphorus 700 mg/day700 mg/day Potassium 4.7 g/day (AI)4.7 g/day (AI) Selenium 55 mcg/day55 mcg/day Sodium (51-70 years) 1.3 g/day (AI)1.3 g/day (AI) Sodium (> 70 years) 1.2 g/day (AI)1.2 g/day (AI) Zinc 11 mg/day8 mg/day *NE, niacin equivalent: 1 mg NE = 60 mg of tryptophan = 1 mg niacin  #Vitamin B12 intake should be from supplements or fortified foods due to the age-related increase in malabsorption  RDA=Recommended Dietary Allowance; AI=Adequate Intake
  • 20. VITAMIN D  generally healthy adults take 2,000 IU (50 mcg) of supplemental vitamin D daily. Most multivitamins contain 400 IU of vitamin D, and single ingredient vitamin D supplements are available for additional supplementation. Sun exposure, diet, skin color, and obesity have variable, substantial impact on body vitamin D levels. To adjust for individual differences and ensure adequate body vitamin D status, aiming for a serum 25-hydroxyvitamin D level of at least 80 nmol/L (32 ng/mL). Numerous observational studies have found that serum 25-hydroxyvitamin D levels of 80 nmol/L (32 ng/mL) and above are associated with reduced risk of bone fractures, several cancers, multiple sclerosis, and type 1 (insulin-dependent) diabetes. Daily supplementation with 2,000 IU (50 mcg) of vitamin D is especially important for older adults because aging is associated with a reduced capacity to synthesize vitamin D in the skin upon sun exposure.
  • 21. CAUSES OF VITAMIN D DEFICIENCY IN THE ELDERLY • habitually low dietary intake (120-200 I.U./d) • impaired synthesis in senile skin (see below) • little sun exposure in homebound and institutionalized elderly people 21
  • 22. RECOMMENDATIONS: (EXPERT PANEL OF THE NATIONAL OSTEOPOROSIS FOUNDATION, 2003)  Women under 50 should consume 1200 mg of calcium and 600 (800) IU of vitamin D  Physical activity  Active strategies to avoid falls  Avoid falls and the consumption of more than two alcoholic drinks per day 22
  • 23. CALCIUM  To minimize bone loss, older men (> 70 years) and postmenopausal women should consume a total (diet plus supplements) of 1,200 mg/day of calcium. Men aged 51-70 years should consume 1,000 mg of calcium per day. No multivitamin/multimineral supplement contains the RDA for calcium (1,000-1,200 mg/day) because the resulting pill would be too large to swallow. If your total daily calcium intake doesn't add up to 1,000 mg, It is recommended to take an extra calcium supplement (combined with magnesium) with a meal.
  • 24. MAGNESIUM  Older adults are less likely than younger adults to consume enough magnesium to meet their needs and should therefore take care to eat magnesium-rich foods in addition to taking a multivitamin-mineral supplement daily. However, no multivitamin/mineral supplement contains 100% of the DV for magnesium. If you don’t eat plenty of green leafy vegetables, whole grains, and nuts, you likely are not getting enough magnesium from your diet. If you add a magnesium supplement, It is recommended a combined magnesium-calcium supplement containing 133-250 mg of magnesium and 333-500 mg of calcium with a meal. Because older adults are more likely to have impaired kidney function, they should avoid taking more than 350 mg/day of supplemental magnesium without medical consultation
  • 25. Lack of vitamin B12 Causes - Poor intestinal absorption - Decreased binding with intrinsic factor eg: - Gastric resection - Atrophic gastritis - Metabolic disorders - Low consumption Consequences - Pernicious anemia - Memory loss - Reduced motor coordination - Myopathia 25
  • 27. SODIUM  There is consistent evidence that diets relatively low in salt (5.8 grams/day or less) and high in potassium (at least 4.7 grams/day) are associated with decreased risk of high blood pressure and the associated risks of cardiovascular and kidney diseases. Diets low in sodium and rich in potassium are likely to be of particular benefit for older individuals, who are at increased risk of high blood pressure. Moreover, the Dietary Approaches to Stop Hypertension (DASH) trial demonstrated that a diet emphasizing fruits, vegetables, whole grains, nuts, and low-fat dairy products substantially lowered blood pressure, an effect that was enhanced by reducing salt intake to 5.8 grams/day or less. It is recommended that a diet that is rich in fruits and vegetables (at least 5 servings/day) and limits processed foods that are high in salt. Sensitivity to the blood pressure-raising effects of salt increases with age; therefore, consuming diets that are low in salt and high in potassium may especially benefit older adults.  Diets rich in potassium (at least 4.7 grams/day) and low in salt (5.8 grams/day or less) are likely to be of particular benefit for older adults, who are at increased risk of high blood pressure along with its associated risks of cardiovascular and kidney diseases. Since sensitivity to the blood pressure-raising effects of salt increases with age, consuming diets that are low in salt and high in potassium may especially benefit older adults.
  • 28. OTHER NUTRIENTS  Essential Fatty Acids  L-carnitine  Flavonoids
  • 29. ESSENTIAL FATTY ACIDS  Alpha-linolenic acid (ALA), an omega-3 fatty acid, and linoleic acid (LA), an omega-6 fatty acid, are considered essential fatty acids because they cannot be synthesized by humans. In 2002, the Food and Nutrition Board of the U.S.Institute of Medicine established adequate intake (AI) levels for omega-6 and omega-3 fatty acids. Essential fatty acid recommendations for adults over the age of 50 are listed below.
  • 30.  Adequate Intake (AI) for Essential Fatty Acids Essential Fatty Acid  ALA (> 50 years) Men 1.6 g/day Women 1.1 g/day  LA (> 50 years) Men 14 g/day Women 11 g/day Abbreviations: ALA=alpha-linolenic acid; LA=linoleic acid; g=grams
  • 31. American Heart Association Recommendation The American Heart Association recommends that people without documented CHD eat a variety of fish (preferably oily) at least twice weekly, in addition to consuming oils and foods rich in ALA. People with documented CHD are advised to consume approximately 1 g/day of EPA + DHA preferably from oily fish, or to consider EPA + DHA supplements in consultation with a physician. Patients who need to lower serum triglycerides may take 2-4 g/day of EPA + DHA supplements under a physician's care.
  • 32. L-CARNITINE  Age-related declines in mitochondrial function and increases in mitochondrialoxidant production are thought to be important contributors to the adverse effects of aging. Tissue L-carnitine levels have been found to decline with age in humans and animals . One study found that feeding aged rats acetyl-L-carnitine (ALCAR) reversed the age-related declines in tissue L-carnitine levels and also reversed a number of age-related changes in liver mitochondrial function; however, high doses of ALCAR increased liver mitochondrial oxidant production . More recently, two studies found that supplementing aged rats with either ALCAR or alpha- lipoic acid, a mitochondrial cofactor and antioxidant, improved mitochondrial energy metabolism, decreased oxidative stress, and improved memory . Interestingly, co-supplementation of ALCAR and alpha-lipoic acid resulted in even greater improvements than either compound administered alone
  • 33. L-CARNITINE  Age-related declines in mitochondrial function and increases in mitochondrialoxidant production are thought to be important contributors to the adverse effects of aging. Tissue L-carnitine levels have been found to decline with age in humans and animals . One study found that feeding aged rats acetyl-L- carnitine (ALCAR) reversed the age-related declines in tissue L- carnitine levels and also reversed a number of age-related changes in liver mitochondrial function; however, high doses of ALCAR increased liver mitochondrial oxidant production . More recently, two studies found that supplementing aged rats with either ALCAR or alpha-lipoic acid, a mitochondrial cofactor and antioxidant, improved mitochondrial energy metabolism, decreased oxidative stress, and improved memory . Interestingly, co-supplementation of ALCAR and alpha- lipoic acid resulted in even greater improvements than either compound administered alone.
  • 34. FLAVONOIDS  Because flavonoids have anti- inflammatory, antioxidant and metal-chelating properties, scientists are interested in the neuroprotective potential of flavonoid-rich diets or individual flavonoids. At present, the extent to which various dietary flavonoids and flavonoid metabolites cross the blood-brain barrier in humans is not known. Although flavonoid-rich diets and flavonoid administration have been found to prevent cognitive impairment associated with aging and inflammation in some animal studies, prospective cohort studies have not found consistent inverse associations between flavonoid intake and the risk of dementia or neurodegenerative disease in humans
  • 35. DIETARY RECOMMENDATIONS  Following careful nutritional assessment, guidelines have been developed to improve and maintain nutritional status in community-dwelling and hospitalized elderly patients. For example, the Canada Food Guide recommends the following daily nutritional intake for adults:  5â€―12 servings of grains  5â€―10 servings of fruits and vegetables  2â€―4 servings of milk products  2â€―3 servings of meat or meat alternatives  Foods high in fibre and complex carbohydrates such as whole grains, vegetables, and fruits are preferred. Fat intake should be less than 30% of total caloric intake
  • 36. A food pyramid for the elderly Sweets and fats in moderation Calcium, vitamin D, vitamin B12, Wholemeal Milk, yogurt, cheese Fish meat legumes 3 portions 2 portions Vegetables Fruit 2 portions 3 portions Wholemeal Cereals and tubers is better 6 portions 36 Water and liquids 8 glasses
  • 37. EFFECTS OF AGING ON NUTRITION  Changes Effects  Sensory Impairment  –Decreased sense of taste ÎReduced Appetite  –Decreased sense of smell ÎReduced Appetite  –Loss of vision and hearing ÎDecreased ability to purchase and prepare food  –Oral health / dental problems ÎDifficulty chewing, inflammation, poor quality diet  Altered energy need ÎDiet lacking in essential nutrients  Decreased physical activity ÎProgressive depletion of LBW and loss of appetite  Muscle loss (sarcopenia) ÎDecreased functional ability, assistance needed with ADLs.
  • 38. ASSESSING NUTRITIONAL STATUS  A comprehensive assessment of nutritional status includes anthropometric measurements,  laboratory values, physical exam, and patient history. Anthropometric measures include  height, weight, body mass index, body fat measurement, muscle mass measurement, and  body mass index. Laboratory values should include albumin, retinal-binding prealbumin, transferring, complete blood count, serum folate, vitamin B12, and cholesterol. A diet history is helpful if there is good 24-hour recall  or a food record for 3 days leading up to the exam can be completed.  the Mini Nutritional Assessment is a basic screening tool.
  • 39. PREVALENCE OF MALNUTRITION IN THE ELDERLY Malnurished At risk Normally nourished Nursing home 14% 53% 33% Hospitalized 39% 47% 14% Rehablitation 50% 41% 9% Community 6% 32% 62%
  • 40. PREVALENCE OF MANUTRITION IN THE ELDERLY  1 of 4 of older adults are malnourished.  2 of 4 of older adults are risk of malnutrition.
  • 41. POSSIBLE CAUSES OF UNINTENTIONAL WEIGHT LOSS:  M Medications  E Emotional Problems  A Anorexia Nervosa  L Late‐life Paranoia  S Swallowing Problems  Oral Factors (cavities poorly fitting dentures)  N No Money  W Wandering and Other Dementia Related  Behaviors  H Hyperthyroidism, Hypothyroidism  E Enteric Problems (malabsorption)  E Eating Problems (inability to feed self)  L Low Salt, Low Cholesterol Diets  S Shopping, Social Problems
  • 42. WEIGHT LOSS  Weight loss in the elderly is a worrisome clinical sign. Weight loss in the elderly due to voluntary or involuntary causes has been associated with mortality (Himes 1999; Newman et al 2001; Baldwin et al 2002). Although lean body mass may decline because of normal physiological changes associated with age (Lissner et al 1991), a loss of more than 4% per year is an independent predictor of mortality (Wallace et al 1995). Rapid weight loss of 5% or more in one month is considered significant and needs to be immediately evaluated by a physician (Jensen et al 2001; Dryden et al 2002). It has been shown that even moderate declines of 5% or more over three years is predictive of mortality in older adults (Newman et al 2001). However, early identification, assessment, and treatment of weight loss and nutritional deficiencies may prevent the morbid sequel of malnutrition.
  • 43. WEIGHT LOSS  Functional, psychological, social, and economic issues associated with concomitant medical problems may all contribute to poor nutrition and weight loss in the frail elderly patient (Bartali et al 2003). A multidisciplinary geriatric assessment can be helpful to fully address all the complex interacting issues of the frail senior, such as Mrs E, who experiences rapid weight loss as a result of malnutrition. This type of comprehensive assessment may include the services of physicians, nurses, dieticians, occupational and physical therapists, speech and language pathologists, and social workers, each of which can lend their respective expertise to the effective diagnosis of the functional, psychological, and socioeconomic contributors to malnutrition in older patients.
  • 44. AGEING AND OBESITY 1. Cardiac disease 2. Tumours 3. Cerebrovascular diseases 4. Chronic pulmonary disease 5. Diabetes mellitus
  • 45. NUTRITIONAL ISSUES ASSOCIATED WITH COGNITIVE IMPAIRMENT AND VASCULAR RISK FACTORS  Malnutrition has been associated with compromised cognitive capacity in the elderly. The decreased ability to prepare a meal, which may adversely affect an elderly patient's ability to ensure sufficient nourishment, has been cited as one of the earliest signs of mild cognitive impairment (MCI), a pre- Alzheimer disease condition (Borrie et al 2003). For persons with moderate to severe Alzheimer disease, forgetting to eat, inability to access food, and apraxia with utensils may further impair oral intake. Living alone, as Mrs E does, further compounds the risk of malnutrition.
  • 46. NUTRITIONAL ISSUES ASSOCIATED WITH COGNITIVE IMPAIRMENT AND VASCULAR RISK FACTORS  Vitamin deficiencies, particularly vitamin B12, B6, and folate, are associated with cognitive impairment (Nilsson et al 2001; Gill and Alibhai 2003; Lehmann et al 2003). Deficiencies in these vitamins are also associated with hyperhomocysteinemia, which is an independent vascular risk factor. The association of hyperhomocysteinemia with vascular disease is a direct dose-response association (Stamphler et al 1992;Selhub et al 1995). Treatment with folate, vitamin B6, and vitamin B12 has been shown to reduce homocysteine levels (Omran and Morley 2000; Nillson et al 2001; Lehmann et al 2003; Scott et al 2004), improve vascular function in hyperhomocysteinemic patients with coronary artery disease (Willems et al 2002), and result in cholesterol plaque regression (Marcucci et al 2003
  • 47. Although a recent secondary prevention randomized controlled trial failed to demonstrate a decrease in morbid vascular outcomes in stroke patients following supplementation with vitamins B6, B12, and folate over two years, it was suggested that confounding factors (such as the initiation of folate fortification in grain supply concurrent with the study) might explain the null findings (Toole et al 2004). More research is needed to clarify the complex interactions between these vitamins and the modification of vascular risk factors.
  • 48. Nutritional interventions have an impact on vascular disease prevention. It is well established that a diet low in fat and cholesterol is beneficial to modifying vascular risk factors. Emerging research suggests that supplementation with omega-3 fatty acids (such as those found in salmon and other cold-water fish), and consuming cruciferous vegetables (such as broccoli, cabbage, and cauliflower) are all associated with stroke prevention (Joshipura et al 1999; Mozaffarian et al 2005; Robinson and Maheshwari 2005) and may be beneficial if integrated into the diet of all elderly patients with vascular disease or vascular risk factors.
  • 49. Nutritional antioxidant supplements are generally believed to be beneficial in reducing free radical cellular and DNA damage. A large epidemiological study found the concomitant use of vitamins C and E is associated with reduced incidences of Alzheimer disease (Zandi et al 2004). More generally, according to a randomized controlled trial, low blood vitamin C concentrations are strongly predictive of mortality in patients aged 75â€―84 years (Fletcher et al 2003). The efficacy of vitamin E in the prevention and treatment of MCI and Alzheimer disease remains controversial. Used alone in a three-year placebo- controlled study, a daily dosage of vitamin E (2000 IU) was not shown to slow the rate of progression to Alzheimer disease in patients with MCI (Petersen et al 2005). A high- dose vitamin E supplementation (>400 IU/day) has been associated with increased mortality (Miller et al 2005).
  • 50. Other important antioxidants with possibly beneficial outcomes include foods with high levels of phytochemicals and flavonoids. Tomatoes, citrus fruit, blueberries, and certain spices (Fusheng et al 2005) have all been linked to reducing oxidative stress and cognitive impairment. Flavonoids and antioxidants in red wine have also been shown to be beneficial in protecting against dementia (Zuccalà et al 2001; Truelson et al 2002). The increasing amount of research in this field holds promise for preventive nutritional strategies based on the benefits of naturally-occurring antioxidants.
  • 51. ANTIOXIDANT FOOD WHEEL OLIVE OIL NUTS AND DRIED A good diet should contain FRUIT PULSEs antioxidants: vitamin C, vitamin E, polyphenols. FRUIT Vitamin C and E make your immune system more efficient COCOA (de la Fuente et al. 1998). ―We age because we oxidise (rust)‖ and anti-oxidants can mitigate the signs of ageing BREAD CEREALS AND POTATOES (Miquel et al. 2002). VEGETABLES S.E.N.E. C.A. 51 2007
  • 52. POTENTIAL CONSEQUENCES OF MALNUTRITION  Impaired immune response  Reduced muscle strength and fatigue  Inactivity  Impaired temperature regulation  Impaired wound healing  Impaired ability to regulate fluid and electrolytes  Impaired psycho‐social function
  • 53. DIET AS ENERGY  The diet should be the source of energy for all daily activities.  Breakfast or lunch should be the highest-energy meals of the day, in order to complete the most important activities.  Dinner should be the least energetic meal of the day, because few activities are done after dinner.  Meals (breakfast in particular) should not be skipped.  The diet should provide calories according to the needs of each individual. 53
  • 54. How many calories after the age of 50? WOMEN LITTLE PHYSICAL ACTIVITY: 1.600 CALORIES MODERATE PHYSICAL ACTIVITY: 1,800 CALORIES ACTIVE LIFESTYLE: 2,000-2,200 CALORIES MEN LITTLE PHYSICAL ACTIVITY : 2.000 CALORIES MODERATE PHYSICAL ACTIVITY : 2.200-2.400 CALORIES ACTIVE LIFESTYLE : 2,400-2,800 CALORIES 54
  • 55. FOODS RECOMMENDED AS A SOURCE OF EACH NUTRIENT PROTEIN: meat, fish, eggs, milk products, pulses (chickpeas, lentils). CARBOHYDRATES: bread, rice, pasta, potatoes, pulses. FATS: olive oil, oily fish, nuts, dried fruit. VITAMINS: fruit and vegetables, olive oil. MINERALS: milk products, nuts and dried fruits, fish, cereals. 55 FIBRE: fruit, vegetables, wholemeal products.
  • 56. Cereals and tubers CEREALS: RICE, BREAD, PASTA, CORN, WHEAT, BARLEY, SPELT AND TUBERS (EG. POTATOES) ARE THE PRINCIPAL SOURCE OF ENERGY. IT IS ADVISEABLE TO USE, AT LEAST SOMETIMES, WHOLEMEAL PRODUCTS. THESE CONTAIN PROTEIN AS WELL, AND ARE RICHER IN MINERALS AND VITAMINS. AMOUNT PER DAY: 6 PORTIONS ONE PORTION, FOR EXAMPLE: HALF A PLATE OF PASTA OR RICE, A SANDWICH, A BOWL OF CEREAL 56
  • 57. Fruit and vegetables FRUIT AND VEGETABLES CONTAIN VITAMINS, FIBRE AND WATER AND MINERAL SALTS. ALIMENTARY FIBRE HELPS YOU TO FEEL MORE FULL AND REDUCE THE RISK OF TUMOURS, DIABETES, AND HEART DISEASE. CHOOSE FRESH SEASONAL OR FROZEN VEGETABLES. IT IS BEST TO STEAM THEM OR COOK THEM IN A PRESSURE COOKER WITH VERY LITTLE WATER. DAILY AMOUNT: 3 PORTIONS OF VEGETABLES 2 PORTIONS OF FRUIT 57
  • 58. Meat, fish and eggs THESE ARE FOODS RICH IN PROTEIN WITH A HIGH BIOLOGICAL VALUE, WITH MINERALS AND B VITAMINS. LEAN MEAT AND FISH ARE PREFERABLE. IT IS BEST TO GRILL THEM, STEAM THEM, OR COOK THEM WITH VERY LITTLE FAT DAILY AMOUNT: 2 PORTIONS 58
  • 59. Milk, yogurt and cheese MILK AND MILK PRODUCTS (CHEESE, YOGURT) PROVIDE CALCIUM, PROTEIN AND SOME VITAMINS. IT IS ADVISABLE TO USE, AT LEAST PARLY SKIMMED, LOW-FAT PRODUCTS. DAILY AMOUNTS: 3 PORTIONS ONE PORTION, FOR EXAMPLE: 50G OF CHEESE, A GLASS OF MILK OR 1 YOGHURT (100 GR) 59
  • 60. Limit animal fats  CHOOSE LEAN MEATS, FISH OR POULTRY (WITHOUT THE SKIN)  REMOVE THE FATTY PARTS BEFORE COOKING  USE LOW-FAT PRODUCTS  USE LITTLE FAT FOR COOKING  CHOOSE VEGETABLE FATS (EXTRA VIRGIN OLIVE OIL)  AVOID FRIED FOOD 60
  • 61. HYDRATION  Water does not give energy, but is fundamental for hydration.  Sugar-free fruit juice, milk and soups can also help with hydration.  The daily dose of liquids should be 1 and a half or two litres.  Fruit and vegetables are a good source of 61 water.
  • 62. VARIETY AND BALANCE: THE KEY TO A GOOD DIET At every meal: protein, carbohydrates, fats, vitam ins, liquids and fibre in adequate proportions. 62
  • 63. KEY POINTS • Avoid chilled, pre-cooked or re-heated meals • Break our food down into three meals and two snacks. • Have a good breakfast with milk or yogurt. • Choose food according to the action necessary to eat it (cut, grind, squash, etc). • Keep to a good body weight and a good level of physical activity. • Drink water frequently during the day. • Chew each mouthful well before swallowing. 63
  • 64. Key Points (2)  Tasty and varied food with aromatic herbs and spices  Avoid the consumption of animal fats  Eat more fish (especially oily fish)  Eat more food rich in complex carbohydrates, fibre, vitamins and minerals (fruit, vegetables, pulses and wholemeal products)  Sugar: is obtained from fruit and milk  Wine: in moderation (1-2 glasse per day); avoid spirits  Salt: limit what you add at the table 64
  • 65. PRACTICAL ACTIVITIES Divide participants into 3 groups: Each participant fills in his or her food diary They swap diaries with others in the group and analyse the diaries, classifying 3 of their choices as healthy, and 3 as unhealthy. Among all the group members the most interesting case is selected to be discussed in the plenary. 65
  • 66. MY DAILY FOOD HABITS TIME 6 8 10 1 1 1 2 2 2 2 6 8 0 2 4 66
  • 67. SELECTION Write in the two columns: UNHEALTHY FOOD HEALTHY FOOD HABITS HABITS Write at least four items 67
  • 68. CASE 1  Mrs E is a 79-year-old female with Alzheimer-type dementia living alone in her own home with assistance only for heavy housework. She has maintained her weight for one year while taking a cholinesterase inhibitor. She sees her family doctor every 6 months. Her most recent check-up revealed a weight reduction of 3 kg from her previous visit. Patient height 160 cm; weight 48 kg [BMI=19 kg/m2].
  • 69. Mrs E has lost 6% of her body weight in six months. This is a cause for concern. Her physician needs to consider causes for weight loss such as new hyperthyroidism, diabetes, malignancy, depression, or oral problems. These can be ruled out by history, physical examination, and laboratory tests. Collateral history from family or caregivers is very important in assessing a person with dementia. Patients with dementia often have an atypical presentation of many illnesses in the elderly, especially in cases of depression.  A medication review is also an important part of the physician's assessment of this patient. For example, cholinesterase inhibitors as a class can cause nausea, vomiting, anorexia, or diarrhea and can be associated with weight loss. In Mrs E's case, she was able to maintain her weight for a year on this medication. For this reason, other causes of weight loss associated with dementia should also be considered. For example, the loss of caregiver support, social isolation, limited access to food, an inability to cook and prepare food because of cognitive problems, or inability to recognize hunger may contribute to her current malnutritive state. Collateral history from a caregiver and a home visit can provide invaluable insight into these issues. Home care nurses or occupational therapists can assist in this assessment.  A nutritional treatment plan for Mrs E may include the treatment of any newly diagnosed medical issues and the prescription of nutritional supplements. In this case, considering a referral to social and community programs (such as adult day care, home care services, or a delivered meal program) would be appropriate at Mrs E's discharge.
  • 70. CASE 2  Mrs A is an 82-year-old female living alone, independent in her activities of daily living, and instrumental activities of daily living2. She has a history of non-insulin- dependent diabetes mellitus requiring insulin, hypothyroidism, osteoarthritis, hypertension (HTN), ischemic heart disease (IHD), obesity, and gastroesophageal reflux disorder (GERD). Mrs E recently suffered a hip fracture following a fall for which she underwent a hip-replacement surgery. Her postoperative course is complicated by a urinary tract infection (UTI) and two episodes of clostridium difficile (C. difficile) colitis. She was transferred to a geriatric rehabilitation unit. Patient height 160 cm; weight 94 kg [BMI = 37 kg/m2].
  • 71. Mrs A's situation is complex and highlights some of the issues of nutritional assessments in the hospital setting. A physician is needed to immediately address Mrs A's other underlying medical problems such as obesity, IHD, GERD, and HTN, prior to her general nutritional assessment by a dietician. Diabetes can be a major issue during her hospital stay. Another possible nutritional issue associated with diabetes is substantial proteinuria brought on by diabetic renal disease. Sequelae of diabetes include autonomic dysfunction, which can result in delayed gastric emptying and poor oral intake. This condition can be exacerbated by the use of narcotics to control postoperative pain, and is further compounded by GERD. Infection and obesity often increase insulin resistance, so blood sugar control should be optimized not only for the long-term morbidity prevention, but also for wound healing.  Prior medical complications and the medications prescribed following her hip surgery are another cause for concern. Mrs A may have had poor oral intake because of her diarrheal illness, or from the side effects of antibiotics used to treat C. difficile arising from her UTI. Many elderly hip fracture patients have muscle deconditioning as a result of being hospitalized and consequently require increased protein supplementation. Serum prealbumin or albumin is usually used to assess nutritional status and monitor improvement through a hospital stay. Although Mrs A is obese with a BMI of 37 kg/m2, she likely has a low albumin level and significant protein undernutrition based on her recent medical history. One complication in the treatment of obese patients is the provision of adequate calories and protein for wound prevention and treatment, muscle reconditioning, and therapy-related exercise while concurrently promoting a loss of total body fat. Generally speaking, achieving an optimal balance of food intake, nutritional status, and healthy body weight is a particular challenge for health practitioners (Sullivan et al 2004), particularly when treating patients with extremely high or low BMI measurements.  Finally, Mrs A's HTN and obesity suggest additional risk factors for ischemic heart disease. Her cholesterol profile prior to her hospitalization would provide additional information in planning long-term nutritional goals at discharge. Sodium, fat, and cholesterol restrictions may be appropriate. Other nutritional goals during Mrs A's hospital stay should include ensuring that she has adequate education to both understand and follow her dietary advice. Referral to a community dietician or diabetic educator is recommended in Mrs A's discharge planning.
  • 72. CASE 3  Mr T is an 83-year-old male who has been living in a nursing home for the past 12 months since suffering a right middle cerebral artery stroke. During this time he has had trouble feeding himself and has lost 10 kg. He has a coccyx ulcer. Patient height 180 cm; weight 55 kg [BMI= 17 kg/m2].
  • 73. Mr T has severe malnutrition with a BMI of 17 kg/m2 and a corresponding high risk of morbidity and mortality. Given his acute nutritive needs following his medical history of stroke (Dennis et al 2005), Mr T's nutritional assessment and treatment plan should include a physician, dietician, speech and language pathologist, and an occupational therapist.  The benefits of stroke rehabilitation are well documented (Gresham et al 1997). One of the first treatments often recommended immediately following a stroke is a swallowing assessment and, if necessary, training to facilitate improved swallowing. For patients who require tube feeding, it has been determined that patients with significant dysphagia who undergo gastronomy tube feeding have less risk of aspiration, earlier discharge from hospital, and higher albumen levels with gastrostomy tube feeding than those who undergo nasogastric tube feeding (Milne et al 2005). Early tube feeding following stroke has been associated with decreased mortality in older patients (Dennis et al 2005).  It is likely that Mr T had the appropriate assessment in hospital following his stroke. Nevertheless, a bedside swallowing assessment performed by a speech and language pathologist is very helpful in determining the type of food consistency that is appropriate in a person with dysphagia. Sometimes it is necessary to refer the patient for a modified barium swallow to further assess their risk for aspiration. Furthermore, positioning and seating are important requirements for successful meals. Occupational therapists can assist with this as well as the provision of special utensils, plates, or placemats in order to better facilitate self-feeding.
  • 74. A number of other possibilities may contribute to Mr T's current condition. For example, Mr T may have extended his stroke resulting in worse dysphagia and subsequently decreased oral intake. Untreated dysphagia may result in protein undernutrition, which can result in compromised immunity and an increased risk of infection (Hudson et al 2000). He may have developed post-stroke depression, which often manifests a decrease in appetite. It is possible that not all of the dietary recommendations of the stroke team were followed after discharge. Sometimes this is because of patient choice; for example, a common recommendation involves restricting patients' diet to pureed foods. Some patients assess the relative risks (which include aspiration) and prefer a diet with varied textures as a quality of life consideration. Nutritional deficiencies have been suggested, but not clinically confirmed, to adversely affect vascular outcomes in stroke (Toole et al 2004).  Mr T needs a comprehensive physical and cognitive examination, and laboratory tests to exclude new medical problems as contributing causes for his weight loss. Since protein undernutrition and low vitamin C levels are associated with poor wound healing and pressure sores, a dietician should participate in Mr T's treatment plan and consider supplementation in vitamin C, zinc, and other trace minerals, in addition to increased caloric and protein intake. His albumin level should be regularly measured to provide objective monitoring of the treatment plan. 
  • 75. KEY POINTS  Age-related changes in physiology and immunity may result in a greater need for vitamin and mineral supplementation in the elderly.  Dietary modifications, such as including foods high in antioxidants and lowering intake of fat and cholesterol, may improve cognition and modify vascular risk factors in elderly patients.
  • 76. KEY POINTS  Hospitalized elderly patients are at particular risk for malnutrition and need to be carefully assessed and aggressively treated.  There are several effective and easy-to-use screening tools which assess for malnutrition in elderly patients. The most extensively validated tool is the Mini Nutritional Assessment (MNA), which provides an accurate assessment of elderly patients from a variety of domiciliary settings.
  • 77. KEY POINTS  Dietary assessment and counseling comprise an important and effective aspect of preventing and treating a variety of morbid conditions in elderly patients.
  • 78. TAKE HOME MESSAGE  Multivitamin supplements are highly recommended for older patients, especially in seniors whose daily caloric intake is less than 1500 kcal/day.  Advise patients about nutrient-dense food choices when appropriate.  Investigate body weight losses of 4% or more.  Nutritional supplements are recommended for at-risk elderly hip fracture patients. Also consider supplements for frail seniors with other fractures.  Calcium and vitamin D supplementation have been shown to reduce hip fracture rates and are recommended for patients over 65 years of age.  Advise patients on the merits of whole grains, fruits, and vegetables.  In hospitalized patients, maintain a high index of suspicion for pre- existing nutritional deficiencies. Utilize the services of a registered dietician.  Consider referrals to other health professionals for nutritional advice such as dieticians, speech and language pathologists, homecare or visiting nurse services, or other specialized geriatric services available in the community.