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Core products
1. Quality Products for Quality Life
Products for a variety of Seasons & Reasons
One the fastest growing pharmaceutical companies CORE GROUP is known
growing,
for developing and marketing one of the lowest cost high quality safe
cost, quality, safe,
effective and proven medicines for a wide variety of seasons and reasons The
reasons.
aim is to help people live longer, live better.
Core Group’s varied product basket includes prescription Antibiotics & Life Saving medicines,
Analgesic & Pain Killers, Gynecological, Pediatric, Gastrointestinal, Orthopedics, Injectibles and
expectorants. The gynecological range may further be sub-divided into Calcium Supplements,
Iron Supplements, Multi-vitamin, Multi-mineral and products for anti-nauseant / antiemetic
management of nausea and vomiting during Pregnancy (NVP). Likewise the gastrointestinal
range includes Anti-emetic, Anti-Anorexia, Antacids and Anti-Secretary medicines.
To add further punch to its gastrointestinal range the company is now launching a new product
called Hitolive (L-ornithine L-aspartate) –a prescription drug for severe liver impairment. L-
Ornithine-L-Aspartate is useful in the treatment of high ammonia levels or when a patient’s
liver function is extremely poor. L-O-L-A is very effective for end-stage cirrhotic patients.
All these products are manufactured as per US Food and Drug Administration (USFDA) and
World Health Organization's Good Manufacturing Practice (WHO GMP) Regulations.
Sometimes also referred to as cGMPs or Current Good Manufacturing Practices these are a set
of regulations, codes, and guidelines for the manufacture of drugs, medical devices, diagnostic
aids and Active Pharmaceutical Ingredients (APIs) to ensure ensures a drug with zero defects.
GMP is a concept that goes beyond manufacturing. It involves commitment to total quality
across the organization. It is something imbibed in the very culture of the organization. One of
the essential requirements of GMP is to maintain high degree of sanitation and hygienic
conditions in the manufacturing facilities and by the personnel operating the machines. The
World Health Organization (WHO) version of GMPs is used by pharmaceutical regulators and
the pharmaceutical industry in over 100 countries worldwide, primarily in the developing world.
Anyone using Core’s products is assured of finest quality, safe and reliable products
manufactured with utmost care. Core’s Group products are manufactured at state-of-the-art
manufacturing facilities conforming to stringent international WHO and GMP norms. The entire
production process is carried out at per well-defined Standard Operating Procedures (SOP) and
quality control checks from raw materials to finished goods. Most of these facilities have ultra-
modern state-of-the-art machinery and trained manpower at each stage to produce world
2. class, safe and reliable pharmaceutical products. Another aspect of Core Group’s strength is
that many of the production units manufacturing its products are US-FDA approved. This is no
mean achievement considering the fact that India has the distinction of having the largest
number of US-FDA approved manufacturing units, outside of the United States for production
of Active Pharmaceutical Ingredient (API).
ANTIBIOTICS & LIFE SAVING PRODUCTS
Core Group’s key strength lies in its vast range of broad spectrum antibiotics and life saving
products. Derived from the synthesis of two Greek words Anti – meaning “against" and Bios –
meaning "life" – Antibiotics – are essentially chemicals that destroy or prevent the growth and
reproduction of many types of germs and bacteria. Antibiotics are powerful medicines that fight
bacterial infections. They can be injected, given orally, or applied to the skin in ointment form.
Antibiotic are commonly classified as Penicillins, Cephalosporins, Fluoroquinolones,
Tetracyclines, Macrolides, Aminoglycosides, Sulfonamides, Carbapenems, Polypeptides and
Nitro-imidazole. Of these Core Group has products under Penicillins (Remoxid-625, Remoxid-
DCL & Remoxid-kid) Cephalosporins (Alcepid, Alcepid kid, Cefiante and Cefiante – Kid)
Fluroquinolones (Levid & Oflina Oz)
GYNEACOLOGICAL:
Another weapon in Core Group’s arsenal is its wide range of Gynecological products ranging
from Calcium supplement with Calcium and vitamin D3 combination (Calider), Iron supplements
(Sanger & Sanger Plus) Antihistaminic–Antiemetic drug for nausea and vomiting during
pregnancy (Folicante-D), comprehensive health supplement with a wide range of vitamins,
minerals and other nutrients that contribute to overall health and wellness (Provytal) and
Nutritional Dietary Supplement with Multi Vitamins & Multi Minerals (Alvitina).
Recent study has demonstrated that giving calcium supplements to women during pregnancy
help prevent tooth decay in the mother as well as child. The study revealed that children whose
mothers who took calcium supplement had a 27 percent less missing teeth and decay in both
permanent and primary teeth. The study went on to suggest that taking calcium supplement by
women during pregnancy provides prolonged protection throughout childhood. When it comes
to that the situation is really grim as most Indian women are calcium deficient. According to
Arthritis Foundation of India, majority of Indian women are calcium as well as Vitamin D
deficient. On an average, a healthy woman needs 1,000 mg of calcium per day. But Indian
women have a dietary intake of around 400-500 mg of calcium a day (provided they take two
glasses of milk, paneer and curd). This in other words means that most Indian women have a
deficiency of almost 500 mg. In addition to this they have Vitamin D levels of around 4 to 12
nanograms, as against a recommended level of around 30 nanograms.
3. For bone health, Vitamin D and calcium go hand in hand. Though itself not a Vitamin but a
Hormone-- Vitamin D keeps bones strong, protects against diabetes, tuberculosis, cancer, colds,
and flu. Studies have indicated Vitamin D deficiency doubles the risk of hypertension during
pregnancy. Vitamin D is essential for the Calcium absorption. Vitamin D helps absorb Calcium
from the digestive tract.
Similarly Iron (Fe) — is essential to most life forms. A component of red blood cells and
muscles, it assists in transportation of oxygen throughout the body. Almost two-thirds of iron in
the body is found in hemoglobin, the protein in red blood cells that carries oxygen to tissues.
Women lose twice the amount of iron than men and are more likely to be deficient, particularly
during the child bearing years. Iron requirements of pregnant women are approximately double
that of normal women because of increased need of the fetus, and blood losses during delivery.
A pregnant woman requires 30mg of iron per day particularly during second and third
trimester. If iron intake does not meet increased requirement, this could lead to iron deficiency
or anemia which is responsible for morbidity, premature deliveries and low birth weight babies.
This apart, Nausea and vomiting (NVP) -- often referred to as "morning sickness" is one of the
most common medical conditions during pregnancy, affecting almost 80% of all pregnant
women. Since each woman and each pregnancy is different, the severity and the management
of NVP will vary from woman to woman.
PEADIATRIC:
Core Group has a well defined pediatric range with MultiVitamins & MultiMinerals drops
(Alvitina-Kid), oral third generation cephalosporin antibiotics (Cefiante-Kid & Alcepid-Kid),
Broad spectrum Penicillin Derivative antibiotic (Remoxid-kid), quinolone antibiotics (Oflina OZ).
ANALGESICS & PAIN KILLERS
Likewise Core Group’s range of Analgesic Painkillers include non-steroidal anti-inflammatory
drug (NSAID) with analgesic and antipyretic properties (Nimante P), Analgesic and Anti-
inflammatory, Antirheumatic for management of moderate to severe or chronic pain (Indoler P
and Indoler APS).
GASTROINTESTINAL
In keeping with its name Core Gestra which itself is derived from “gastric” or relating to the
stomach or digestive tract, the Company’s gastrointestinal collection includes proton pump
inhibitors for treatment of peptic ulcer and gastro-oesophageal reflux disease (GERD) (Lapanto
40 and Lapanto DSR), digestive aid for easy digestion of starch, carbohydrates, fats & proteins
and mitigation of loss of appetite (Easy Zyme) and antacid (Mycid Gel).
4. ORTHOPEDIC:
Core Group’s Orthopedic product range include Calcium supplement with vitamin D3 (Calider),
centrally acting opioid analgesic, used in treating moderate to severe pain (Indoler P and
Indoler APS), non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic
properties (Nimante-P)
INJECTIBLES:
A popular belief, particularly in rural India is that injections are more effective and act faster
than oral medication. Tablet, Syrup, Inhaler, Ointment, Capsule or Injection— ever since times
immemorial, an ongoing debate in the medical fraternity has been to find out the most
appropriate means of administrating a particular medication to a particular patient. It would
not be wrong to say that it’s one thing to take the right medicine but unless it is absorbed in the
body in sufficient quantity… it does not work.
All over the world injections have become one of the most common medical procedures in
formal and informal health care settings today. According to an estimate over 40 billion
injections are administered worldwide annually.
Injections are one of the fastest ways of getting a drug to the brain by injecting it directly into
the bloodstream. Intravenous injection ("mainlining") triggers effects almost before a user can
pull out the needle. Given at the right time and right manner an injection can make a difference
between life and death. The effect of the injection can also be formulated to last days or
months.
Typically the Core Group’s injectible range includes amino glycoside used to treat different
types of bacterial Infections (Amikante), third-generation cephalosporin antibiotics (Triader &
Triader S) Proton Pump Inhibitor (PPI) that suppresses the final step in gastric acid production
(Lapanto 40 Inj) and extended-spectrum penicillin antibiotic (Pipante TZ).
EXPECTORANT
When diabetes and hypertension are fast becoming lifestyle altering diseases, cough and cold
medications still remain the largest selling segment in the Indian pharma market. With
phenomenal total sales worth Rs 270 crore, Cough and cold formulations were clearly among
the 10 top selling brands in the domestic market. Core Group’s presence in this marketed is
market by its champion brand Moredex-AT (Terbutaline Sulphate + Bromhexine Hcl +
Guaiphensin + Menthol)—an expectorant. By definition expectorants are medication that helps
bring up mucus and other material from the lungs, bronchi, and trachea, promote drainage of
mucus from the lungs by thinning the mucus and also lubricate the irritated respiratory tract.
Moredex-AT eases respiratory function, breaks down mucus and facilitates expectoration.
5. Terbutaline is a bronchodilator to make breathing easier. Bromxhexine functions as a
mucolytic and mucokinetic, and facilitates ciliary clearance of the sputum while Guaiphenisin--
an expectorant, acts by enhancing the output of respiratory tract fluid. By increasing the
volume of secretions in the respiratory tract, it facilitates sputum removal by ciliary action and
coughing. Moredex-AT is prescribed for relief from Cough & cold, wet cough, Allergic Cough,
Smoker Cough and Pain relief.
Core Group aim always and every time, is to create brands people love and contribute to a
better and healthier world. Core Group’s unending quest is to provide specialty products and
innovative solutions - that can satisfy unmet medical needs and contribute to the health and
well being of faceless and hopeless people worldwide.