What advantages does Cinderella’s approach bring? Important advantages are illustrated in this presentation, including renouncing the profit principle, restarting the interrupted development of drugs considered to have insufficient potential for the generation of profits and bringing new drugs to patients for an affordable price by using a scientifically and economically sound study design
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Cinderella's approach
1.
2.
3. Cinderella is the first Dutch not-for-profit
organization making new drugs available for an
affordable price.
4. Cinderella focuses on step child drugs:
Promising drugs, but of low interest to the
commercial pharmaceutical industry due to their
low potential to generate profits.
5. Cinderella is convinced
the clinical development of stepchild drugs can be
completed successfully by the application on novel
study methodology.
6. To reach this goal
Cinderella renounces the profit principle and adopts
top clinical physician/scientists to execute her
projects. Charity organizations and individuals who
subscribe to Cinderella’s approach will provide the
necessary financial support .
7.
8. Initiate development of stepchild drugs
by initiating clinical:
Renouncing the profit principle.
Selecting the most promising step child drugs.
9. Cinderella’s drug selection:
Drugs shelved by the pharmaceutical industry
for their lack of profit making potential.
Drugs promising a high therapeutic ratio based
on results obtained in preclinical research and
phase 1 studies.
10. Cinderella is only interested in phase 2 studies:
Phase 2 studies can be completed
in a brief period of time at low costs
Short study duration and low costs are achieved by
entering limited numbers of patients on study
(approx. 30).
11.
12. Drugs shelved for their inability to generate a
sizeable profit can still be studied in patients.
Advantages of Cinderella’s approach:
13. Drugs shelved for their inability to generate a
sizeable profit can still be studied in patients.
All studies focused on improving the quality of life
of the patient. Top medical specialists are the
principal investigators.
Advantages of Cinderella’s approach:
14. Drugs shelved for their inability to generate a
sizeable profit can still be studied in patients.
All studies focused on improving the quality of life
of the patient. Top medical specialists are the
principal investigators.
Coordination is in the hands of the Cinderella
Therapeutics Research Corporation.
Advantages of Cinderella’s approach:
15. Drugs shelved for their inability to generate a
sizeable profit can still be studied in patients.
All studies focused on improving the quality of life
of the patient. Top medical specialists are the
principal investigators.
Coordination is in the hands of the Cinderella
Therapeutics Research Corporation.
A corporate approach leads to higher efficiency.
Advantages of Cinderella’s approach:
17. Cinderella subscribes to
the open source principle.
Obtained results will be published forthwith
in scientific journals.
Advantages of Cinderella’s approach:
18. Cinderella subscribes to
the open source principle.
Obtained results will be published forthwith
in scientific journals.
Patent applications to protect commercial
interests have become obsolete.
Advantages of Cinderella’s approach:
20. No marketing costs.
Therapies found to be ineffective in Cinderella
studies will not increase the price charged
for other, new and effective Cinderella therapies.
Advantages of Cinderella’s approach:
21. No marketing costs.
Therapies found to be ineffective in Cinderella
studies will not increase the price charged
for other, new and effective Cinderella therapies.
Cinderella’s new type of drug development will be
10 to 100 times cheaper than the current drug
development strategy of the Pharmaceutical
Industry.
Advantages of Cinderella’s approach:
