The document provides an overview of the human gastrointestinal system, including its main components and functions. It describes the pathway that food takes through the digestive system, starting with ingestion in the mouth and ending with elimination in the large intestine and anus. Key parts discussed include the mouth, esophagus, stomach, small intestine, large intestine, liver, gallbladder and pancreas. The roles of saliva, gastric juices, enzymes, hormones and bile in breaking down food are also summarized.
2. • Takes in (ingests) raw
material
• Breaks it down (digests)
both physically and
chemically to usable
elements
• Absorbs those elements
• Eliminates what isn't
usable
Gastrointestinal System
4. • Digestive tract, often
called alimentary
tract or canal, is
muscular tube that
contains organs of
digestion
• Tube begins with
mouth and ends at
anus
Alimentary Canal
9. • Mouth (oral cavity)
is mucous-lined
opening; also called
buccal cavity
• Lips (labia) act as
door to cavity
• Hard and soft
palates create roof
Oral Cavity
10. • Tongue acts as
floor
• Tongue's base
and uvula act as
boundary between
oral cavity and
pharynx
Oral Cavity-Tongue is Border
11. • Uvula aids in
swallowing,
directing food
toward pharynx and
blocking food from
entering nose
• Tonsils help in
fighting infection as
part of lymphatic
system
• Teeth for grinding
food
Oral Cavity-Uvula, Teeth & Tonsils
12. Salivary Glands Begin Breakdown of Food
• Sides of cavity created by
cheeks
• Mouth receives, tastes,
mechanically breaks
down, and begins process
of chemical breakdown
of food, adding saliva
Oral Cavity
14. • Tongue is muscle that
provides taste stimuli to
brain, determines
temperature,
manipulates food, aids
in swallowing
• As tongue moves food
around in oral cavity,
saliva added to
moisten and soften it,
while teeth crush food
Tongue
15. • Tongue pushes food
into ball-like mass,
called bolus, so it may
be swallowed, passed
to pharynx
Tongue
16. • Lingual frenulum,
membrane under
tongue, keeps you
from swallowing your
tongue and aids in
speaking
Tongue-The
Frenulum
18. Large Parotid Salivary Gland
• Controlled by
autonomic nervous
system
• Found slightly inferior
and anterior to each
ear; these swell
when you get mumps
Salivary Glands-3 Pairs
19. Sublingual and Submandibular Salivary Gland
• Sublingual salivary
glands: located
under tongue
• Submandibular
salivary glands: on
both sides along
inner surfaces of
mandible, or lower
jaw
Salivary Glands-3 Pairs
20. *Sight of food can stimulate secretion of saliva*
• Salivary glands
produce 1–1.5 liters of
saliva daily
• Saliva is 99.4%
water; contains
antibodies, buffers,
ions, waste products,
and enzymes
Salivary Glands
21. Salivary Amylase breaks down Carbohydrates
• Enzymes are
biological catalysts to
speed up chemical
reactions
• Salivary amylase:
speeds chemical
activity of breaking
down
carbohydrates
Salivary Glands-Enzymes
22. Ptyalin converts starches to simple sugars
• Enzymes are
biological catalysts to
speed up chemical
reactions
• Ptyalin: specific
salivary amylase
that converts
starches to simple
sugars
Salivary Glands-Enzymes
23. • After eating,
saliva cleans
oral surfaces,
reducing amount
of bacteria that
grows in mouth
Less bacteria in the mouth
Saliva Cleans Teeth
25. • Nasopharynx: primarily
part of respiratory
system,
• Oropharynx and
laryngopharynx: act as
passageway for food,
water, and air
• Epiglottis: covers
trachea to prevent food
from entering lungs,
forcing food into opening
for esophagus
Pharynx-3 Parts
26. • Approximately ten
inches long;
connected to stomach
• Extends from pharynx,
through thoracic cavity,
and diaphragm,
connecting to
stomach in peritoneal
cavity
Esophagus
28. • Pharyngo esophageal
sphincter, relaxes to
open esophagus so food
can enter
• Walls lined with
stratified squamous
epithelium that secrete
mucus to make walls
slippery
Esophagus
29. Condition called GERD caused by
incompetent sphincter
• At entrance to stomach
is lower esophageal
sphincter, or cardiac
sphincter, opening door
to stomach and closing
to prevent acidic
gastric juices from
splashing into
esophagus causing
heartburn
Esophagus
30. Located under the diaphragm,
mid to left upper quadrant
Stomach
• Approximately ten
inches long with
diameter
dependent on how
much just eaten
• Can hold up to four
liters when filled
• Rugae, or folds,
help stomach
expand and
contract
32. • Liquids pass through
fairly quickly
• Carbohydrates move
through quickly
• Proteins take more
time to pass through
• Fats take longest,
usually between 4 to 6
hours
Stomach
Movement of material
through stomach
33. • FOUR REGIONS
• Near heart is cardiac
region, surrounding
lower esophageal
sphincter
• Fundus, lateral and
slightly superior to
cardiac region,
temporarily holds food
as it enters stomach
Stomach
34. • FOUR REGIONS
• Body is mid portion of
stomach
• Funnel-shaped, terminal
end of stomach called
pylorus; most of work
of stomach performed
here; where food passes
through pyloric sphincter
into small intestine
Stomach
35. Food “churned up” by muscles of the stomach
• Muscular action works
like cement mixer,
achieved by three
layers of muscles:
longitudinal layer,
circular layer, and
oblique layer
Stomach
36. • Churns food as it
mixes with gastric
juices excreted by
gastric glands in
gastric pits of
columnar epithelial
lining of stomach
Stomach
37. • Works food toward
pyloric sphincter
through peristaltic
activity of
muscles
• Both chemical and
physical digestion
occurs here
Stomach
39. • Pepsin, chief digestive
enzyme
• Pepsin breaks down
protein; HCl breaks
down connective tissue
Stomach-Gastric Juices
40. • HCl has pH of 1.5 to 2;
effective at killing
pathogens
• Mucous cells generate
thick layer of mucus
shielding stomach from
effects of HCl
Stomach-Gastric Juices
41. • Stomach also secretes
intrinsic factor, allowing
vitamin B12 to be
absorbed
Stomach-Vitamin 12 Absorbed
45. Cephalic phase
Sensory stimulation (sight or
smell of food) stimulates
parasympathetic nervous
system via medulla
oblongata, stimulating
release of gastrin which
travels through bloodstream
and reaches stomach,
stimulating gastric gland
activity
Gastric Juice Production
46. Gastric phase
•Two-thirds of gastric juices
secreted as food enters
stomach and distends,
signaling stomach to secrete
more gastric fluid
Gastric Juice Production
47. Intestinal phase
•Food enters duodenum,
distending and sensing
acidity, causing intestinal
hormones to be released,
slowing gastric gland
secretions; lasts until bolus
leaves duodenum
Gastric Juice Production
49. • Located in central
and lower
abdomen
• Functions as major
organ of digestion;
where most of food
digested
Small Intestine
50. • Small in diameter,
not length; longest
section of alimentary
canal; length up to
20 feet and
diameter ranging
from 4 cm where it
connects to stomach
and 2.5 cm where it
meets large intestine
Small Intestine
51. Walls secrete digestive
enzymes, important for
final stages of chemical
digestion, and two
hormones that stimulate
pancreas and
gallbladder to act, and
control stomach activity
Figure 15-10
The small intestine.
52. Villi in small intestine increase
surface area for absorption
• 80% of absorption of
usable nutrients
occurs when chyme
comes in contact with
mucosal walls; amino
acids, fatty acids,
simple sugars, vitamins,
and water are all
absorbed here into
bloodstream and cells
Small Intestine-Villi
53. • Remaining 20%
absorbed in
stomach
• Any residue not
utilized in small
intestine sent to
large intestine for
removal from body
Small Intestine
54. Duodenum:, located
near head of pancreas;
Jejunum: middle section,
2.5 m long
Ileum: terminal end, 6–
12 feet long; attaches to
large intestine at ileocecal
valve
Small Intestine-3 Sections
55. • Pancreas and
gallbladder add
secretions: bile from
gallbladder
• Pancreatic juice
from pancreas
• Bile emulsifies fat,
making fat disperse in
water
Small Intestine-Pancreas &
Gallbladder
56. • Mechanical and
• Chemical irritation
of acidic chyme, plus
• Distention of
intestinal walls,
creates localized
reflex action that
causes release of
enzymes and two
hormones
Small Intestine
57. • Secretin from
duodenum stimulates
secretion of enzymes
and sodium
bicarbonate from
pancreas, which
neutralizes acidic
chyme
• Cholecystokinin (CCK)
secreted by duodenum
stimulates gallbladder
activity
Small Intestine-2 Hormones
59. • Muscular action occurs in
two ways
• Segmentation causes mixing
of chyme and digestive
juices like cement mixer
• Peristalsis moves food
toward large intestine
Small Intestine
Chyme
60. Acinar cells secrete digestive
enzymes in the small intestine
• Digestive enzymes
needed to
complete
chemical
digestion are
produced by
exocrine cells
Small Intestine
61. Nutrients travel to Liver
before going to the body
• Capillaries absorb and
transport sugars
(result of carbohydrate
digestion) and amino
acids (result of protein
digestion) to liver for
further processing
before being sent
throughout body
Small Intestine
62. • Glycerol and fatty acids
(obtained from fat digestion)
are now a white, milky
substance called chyle
• Chyle goes directly into
lymphatic system for
distribution into bloodstream
Small Intestine
66. Approximately five feet
long and 2.5 inches in
diameter; divided into
three main regions:
cecum,
colon, and
rectum
Pouch-shaped structure,
cecum, receives
undigested food and
water from ileum
Figure 15-12
The large intestine.
67. • Some of water used in
digestion and
electrolytes
reabsorbed in cecum
and ascending
colon; water absorbed
is small amount, but
crucial to maintaining
proper fluid balance
Large Intestine
68. • Attached to
cecum
• Three inches
long, slender,
hollow, deadend tube lined
with
lymphatic
tissue
Appendix
69. • Reservoir for
useful bacteria
to replace
bacteria lost
in intestines
as result of
diseases
Appendix
70. • If becomes
blocked or
inflamed, causes
appendicitis and
must be treated
with either
antibiotics or
surgical removal
Appendix
71. • Four sections of
colon:
•
•
•
•
•
Ascending,
Transverse,
Descending, and
Sigmoid
Ascending colon travels
up right side to level of
liver
Large Intestine
72. • Transverse colon
travels across
abdomen just below
liver and stomach
• Descending colon
bends downward near
spleen and travels to
left side becoming
sigmoid colon
Large Intestine
73. • Sigmoid colon
extends to rectum
• Rectum opens to anal
canal that leads to
anus
• Anus relaxes and
opens to allow
passage of solid waste
(feces)
Large Intestine
74. • Peristalsis continues
in large intestine, but
at slower rate
• As slower
intermittent waves
move fecal matter
toward rectum,
water is removed,
turning it from
watery soup to
semisolid mass
Large Intestine
75. • As rectum fills
with feces,
defecation reflex
occurs, which
causes rectal
muscles to
contract and
anal sphincters
to relax
Rectum
76. • If fecal matter moves
through too rapidly,
not enough water is
removed and
diarrhea occurs
• Conversely, if fecal
matter remains too
long in large
intestine, too much
water is removed and
constipation occurs
Diarrhea/Constipation
77. • Bacteria in bowel play
two important roles:
• Help break down
indigestible materials
• Produce B complex
vitamins and most of
vitamin K needed for
proper blood clotting
Large Intestine
78. • Besides salivary glands found in mouth, other
accessory organs needed for digestion:
• Liver
• Gallbladder
• Pancreas
Accessory Organs
79. • Weighs 1.5 kg, located
below diaphragm;
largest glandular organ
in body, and largest
organ in abdomino
pelvic cavity
• Organ performs many
functions vital to life
Liver
80. • Divided into large
right lobe and
smaller left lobe;
right side has
anterior lobe and
two smaller,
inferior lobes
Liver
81. • Receives about 1.5
quarts of blood every
minute from portal
vein (carrying blood
full of end products of
digestion) and
hepatic artery
(providing oxygen-rich
blood)
Liver-Portal Vein
86. • Secretion of
hormone secretin
stimulates bile
production, critical
liver digestive
function
Liver and Bile Production
87. • Salts found in bile
act like detergent,
breaking fat up
into tiny
droplets; process
called
emulsification,
making work of
digestive enzymes
easier
Liver and Bile Production
88. • Bile helps absorb
fat from small
intestine and
transports bilirubin
and excess
cholesterol to
intestine for
elimination
Liver and Bile Production
89. • Bile leaves liver via
hepatic duct,
travels through
cystic duct to
gallbladder, and is
stored there until
needed by small
intestine
Gallbladder Stores Bile
90. • Sac-shaped
organ, 3 to 4
inches long,
located under
liver's right lobe
Gallbladder
91. • While storing bile
absorbs much of its
water content,
making it 6 to 10
times more
concentrated; if too
much water
reabsorbed, bile salts
may solidify into
gallstones
Gallbladder and Gallstones
92. • Fatty foods in
duodenum cause
release of CCK
• Release causes
smooth muscle walls
of gallbladder to
contract, squeezing
bile into cystic duct,
through common bile
duct, and into the
duodenum
Gallbladder and Bile
93. Secretes insulin from cells in Islets of Langerhans
• Plays role in
digestion, as well as
being endocrine
gland
• 6 to 9 inches long,
located posterior to
stomach, and
extends laterally
from duodenum to
spleen
Pancreas
98. • Generally include one
or more of the
following:
•
•
•
•
Vomiting
Diarrhea
Constipation
Abdominal pain
Common Symptoms of Digestive
System Disorders
99. • Vomiting
• Protective
mechanism, ridding
digestive tract of
irritant or overload
of food that
stimulates sensory
fibers, sending signal
to vomiting center in
brain
Common Symptoms of
Digestive System Disorders
100. • Vomiting
• Motor impulses sent
to diaphragm and
abdominal muscles
to contract,
squeezing
sphincter at
esophageal
opening, and
contents are
regurgitated
Common Symptoms of
Digestive System Disorders
101. • Diarrhea
• Fluid contents in small
intestine rushed through
large intestine without
reabsorbing enough
water
• Proper absorption of
electrolytes and
nutrients prevented;
can cause serious
problems
Common Symptoms of
Digestive System Disorders
102. • Diarrhea
• Frequent loose and
watery bowel
movements
• Caused by infection,
poor diet, toxins,
food allergies or
irritants, and stress
Common Symptoms of
Digestive System Disorders
103. • Constipation
• Opposite of
diarrhea; feces
pass too slowly
through colon
and too much
water is
reabsorbed;
stool becomes
hard, dry,
difficult to pass
Common Symptoms of Digestive
System Disorders
104. • Constipation
• May be over
stimulation of
musculature of
intestine
creating more
narrow passage
for material
Common Symptoms of
Digestive System Disorders
105. • Constipation
• May be musculature has
become flaccid or slow
as often found in
bedridden geriatric
patients
Typical “FOS” Xray
Common Symptoms of Digestive
System Disorders
106. • Constipation
• Dietary changes with
more liquid, more
roughage,
reestablishment of
regular bowel habits,
avoidance of
stress/tension,
moderate exercise can
contribute to improving
condition
Common Symptoms of Digestive
System Disorders
107. • Constipation
• Chronic use of
laxatives and
enemas should be
avoided; may
aggravate existing
conditions or create
new ones
Common Symptoms of Digestive
System Disorders
108. • Pain
Large amount of gas can cause
temporary pain until released
• Can be sharp, dull,
localized, diffuse,
radiating,
occasional, or
constant
• Severity of pain does
not always indicate
severity of disease
Common Symptoms of Digestive
System Disorders
109. • Pain
• Stomach cancer may initially present with relatively mild
form of indigestion
• Any pain from GI tract should be investigated
Common Symptoms of Digestive
System Disorders
110. Review SOAP Note on
Gastrointestinal
Disease
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Case Study