Gene Ontology & ChEBI -- cross products
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defining GO process terms using ChEBI terms
![Many GO terms are implicitly composite ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]](https://image.slidesharecdn.com/go-chebi-xp-intro831/85/gene-ontology-chebi-cross-products-1-320.jpg)
![Opaque references to other OBO ontologies ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]](data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7)
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Gene Ontology & ChEBI -- cross products
- 5. GO: now is_a GABA biosynthesis GABA metabolism amino acid biosynthesis amino acid metabolism GO
- 6. GO+ChEBI: now is_a GABA biosynthesis GABA metabolism amino acid biosynthesis amino acid metabolism GO amino acid GABA ChEBI
- 7. Linking GO to ChEBI is_a GABA biosynthesis GABA metabolism amino acid biosynthesis amino acid metabolism GO amino acid GABA ChEBI
- 8. Can we find missing links? is_a GABA biosynthesis GABA metabolism amino acid biosynthesis amino acid metabolism GO amino acid GABA ChEBI
- 12. [Term] id: GO:0009447 name: putrescine catabolic process intersection_of: GO:0009056 ! catabolism intersection_of: results_in_division_of CHEBI:17148 ! putrescine [Term] id: GO:0009448 name: gamma-aminobutyric acid metabolic process intersection_of: GO:0008152 ! metabolism intersection_of: has_participant CHEBI:16865 ! gamma-aminobutyric acid [Term] id: GO:0009449 name: gamma-aminobutyric acid biosynthetic process intersection_of: GO:0009058 ! biosynthesis intersection_of: results_in_change_to CHEBI:16865 ! gamma-aminobutyric acid [Term] id: GO:0009450 name: gamma-aminobutyric acid catabolic process intersection_of: GO:0009056 ! catabolism intersection_of: results_in_division_of CHEBI:16865 ! gamma-aminobutyric acid
- 14. [Term] id: anon_chemical_16 namespace: chebi_ontology is_anonymous: true union_of: CHEBI:27775 ! P(1),P(3)-bis(5'-adenosyl) triphosphate union_of: CHEBI:27529 ! P(1),P(2)-bis(5'-adenosyl) triphosphate [Term] id: anon_chemical_17 namespace: chebi_ontology is_anonymous: true union_of: CHEBI:16019 ! prenol union_of: CHEBI:26244 ! prenols [Term] id: anon_chemical_18 namespace: chebi_ontology is_anonymous: true union_of: CHEBI:28266 ! fluorene union_of: CHEBI:24059 ! fluorenes [Term] id: anon_chemical_19 namespace: chebi_ontology is_anonymous: true union_of: CHEBI:17563 ! phthalate(2-) union_of: CHEBI:30800 ! phthalate(1-) [Term] id: GO:0015962 name: diadenosine triphosphate metabolic process intersection_of: GO:0008152 ! metabolism intersection_of: has_participant anon_chemical_16
Notes de l'éditeur
- orthogonal domains which do not fit into GO’s 3 axes (for the sake of brevity we omit discussion about intra-GO cross-products )