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39 pasko pcrrt drug dosing
1.
Drug Dosing in
PCRRT Deb Pasko, Pharm.D Pharmacy Clinical Specialist, PICU University of Michigan Health System
2.
3.
4.
Joy MS, Matzke
GR, Frye RF, Palevsky PM. AJKD 1998;31:1019-27 .
5.
6.
7.
Vancomycin overdose case
8.
9.
10.
11.
Sieving Coefficient &
Protein Binding 0.10 0.22 Valproic Acid 0.90 0.80 Vancomycin 0.85 0.78 Ranitidine 0.50 0.68 Penicillin 0.80 0.84 Metronidazole 0.80 0.78 Imipenem 0.95 0.93 Amikacin Free Fraction Reported SC Drug
12.
13.
Non-renal clearance rates
of selected drugs in patients with normal renal function and ESRD
14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
24.
Antibiotic Guidelines UM
25.
26.
27.
28.
29.
30.
31.
32.
33.
34.
35.
36.
Phenobarbital case 25.9
Post-hemodiafilter 11.4 Effluent 26.2 Pre-hemodiafilter 24.7 Post-oxygenator 26.5 Pre-oxygenator Concentration (mg/L) Site
37.
38.
39.
Mueller BA, Pasko
DA. Artif Organs 2003;27:808-14.
40.
41.
42.
43.
44.
45.
PCRRT &
Roller pump
46.
47.
CRRT Dosing should
not be confusing!
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