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CELL PHONES ANDCELL TOWERSHealth Risk and Precautionary Principle 
Dariusz Leszczynski,PhD, DSc 
Adjunct Professor, University of Helsinki 
Editor-in-Chief of Frontiers in Radiation and Health 
(specialty of the Frontiers in Public Health, Lausanne, Switzerland) 
Member of the Advisory Board, Cellraid, Ltd, Oulu, Finland 
Dariusz Leszczynski in INDIA, September 15 -19, 2014
Who I am... few examples of my experience 
•Adjunct Professor at the University of Helsinki, Finland 
•Chief Editor of ’Radiation and Health’; specialty of Frontiers in Public Health 
•Two doctorates in biochemistry and in cell biology 
•22 years (1992-2013) at Finnish Radiation and Nuclear Safety Authority 
•2003-2007 as Head of Radiation Biology laboratory 
•2000-2013 as Research Professor 
•Assistant Professor at Harvard Medical School 1997-1999 
•Guangbiao Professor at Zhejiang University, Hangzhou, China 2006-2009 
•Visiting Professor at Swinburne University of Technology, Melbourne, Australia 2012/2013 
•Testified in US Senate hearing on cell phones and health, in 2009 
•Expert in IARC 2011 classification of carcinogenicity of cell phone radiation 
Dariusz Leszczynski in INDIA, September 15 -19, 2014
WHO defintion of health 
“Healthisastateofcompletephysical,mentalandsocialwell-beingandnotmerelytheabsenceofdiseaseorinfirmity” 
WheneverdiscussingsafetyofradiationemittedbythewirelesscommunicationdevicesweneedtorememberthisWHOdefinitionofhealth 
Dariusz Leszczynski in INDIA, September 15 -19, 2014
Safety standards –who sets? 
•Set by ICNIRP -International Commission on Non-Ionizing Radiation Protection 
•ICNIRP’s membership: by invitation only “private club” 
•Membership of ICNIRP based on similarity of scientific opinions of experts 
•No accountability for ICNIRP experts 
•Limited scientific debate when all ICNIRP members have a similar opinion 
•WHO EMF Project recommends use of ICNIRP safety standards 
•WHO EMF Project was started and run by former ICNIRP Chairman -Dr. Repacholi 
Dariusz Leszczynski in INDIA, September 15 -19, 2014
ICNIRP sets 
safety standards 
WHO recommends to use 
ICNIRP safety standards 
In Finland Ministry considers 
WHO recommendation 
In Finland Ministry asks STUK 
opinion on ICNIRP standards 
STUK expert recommends 
use of ICNIRP standards 
STUK expert is ICNIRP member 
who prepared safety standards 
Setting safety standards in… Finland 
Dariusz Leszczynski in INDIA, September 15 -19, 2014
Safety Standards –short-comings 
•Based on thermal effects of cell phone radiation 
•Not accounting for other parameters of exposure 
•Dosimetry based on macro-scale temperature changes 
•Lack of micro-scale dosimetry 
•Models do not resemble living cells and organs 
•Comparisons to classical heating do NOT apply 
Dariusz Leszczynski in INDIA, September 15 -19, 2014
Macro-scale dosimetry 
Water 
Salt 
Sugar 
+ 
= 
Problem: 
free movement of ions 
Dariusz Leszczynski in INDIA, September 15 -19, 2014
Problems associated with the safety standards 
•No information whether/how cell phone radiation affects humans 
•No certainty that safety standards protect all users from anything besides thermal effects 
•Any equipment radiating below safety standards is considered safe which might be misleading 
•Compliance with safety standards is used as an excuse to stop research funding and to deploy new wireless technologies without any testing 
•Non-thermal effects exist but are refused to be studied in depth because of the “excuse” of safety standards 
Dariusz Leszczynski in INDIA, September 15 -19, 2014
IARC evaluation may 2011 
•30 invited experts divided into four sub-groups 
•Dosimetry 
•Epidemiology 
•Animal studies 
•Mechanistic laboratory in vitrostudies 
•Decissions done by consensus or by simple majority 
•The vast majority of experts voted for possible carcinogen classification 
Dariusz Leszczynski in INDIA, September 15 -19, 2014
IARC 2011 and after IARC: Epidemiology 
•Interphone & Hardellstudies 
•no reliable exposure data 
•risk increase in long-term avid users 
•Children –only CEFALO 
•exposures for 2-4 years 
•has no statistical power to detect small risk 
•Trend-data -Little et al. 2012: slow rise of brain cancer cases in USA 
•trend is similar to Interphone “prediction” but not Hardell“prediction” 
•Danish Cohort update study –no effect but no exposure data at all 
•Million Women study -no effect but exposure data inadequate 
Dariusz Leszczynski in INDIA, September 15 -19, 2014
The limited human evidence was based on the results of two sets of epidemiological studies European Interphone group and Hardellgroup in Sweden. 
After the IARC evaluation, in 2014, was published a new epidemiological study -the French CERENAT. 
The French study reached similar conclusions as Interphone and Hardellpreviously – long term avid use of cell phone increases a risk of developing brain cancer. 
It means that now there are three replications of the same epidemiological type of study, the case-control study, that all suggest cell phone radiation might increase a risk of brain cancer. 
After IARC evaluation: Epidemiology
IARC 2011: Human studies 
•The vast majority are “feelings” studies 
•Subjects asked how they feel 
•Subject asked do they feel when radiation is on/off 
•EHS must exist –question is only of radiation cut-off level 
•Otherwise RF would be the only factor not causing individual sensitivity in people 
•Problem of EHS –studied by psychologists not physiologists –wrong methods 
•WHO definition of health –how to consider it? IARC classification justifies reasoning for “mental and social well-being” 
•Lack of studies examining biochemical responses of human tissues 
•Single skin proteomics study 
•Two studies examined glucose metabolism in the brain 
•That is all! 
Dariusz Leszczynski in INDIA, September 15 -19, 2014
IARC 2011: Animal studies 
•No classical toxicology possible 
•By classical toxicology RF would be judged as harmful to humans 
•Not possible to overdose cell phone radiation because of heating effect 
•Life-time exposures to radiation doses similar to those emitted by cell phones show no effect –result useless for human health risk estimation 
•Co-carcinogen studies show some effects –cell phone radiation might potentiate effects of carcinogenic chemicals or radiation 
Dariusz Leszczynski in INDIA, September 15 -19, 2014
*…but… what nobody is speaking about! 
Risk evaluation of radiation emitted by the base stations: 
scientific studies where exposure levels are similar to levels emitted by cell phones can be considered as toxicology studiesexamining effects of radiation emitted by base stations 
Dariusz Leszczynski in INDIA, September 15 -19, 2014
IARC 2011: Mechanistic studies 
•Laboratory evidence was considered, by voting (no consensus) as insufficient to support/show mechanism of cell phone radiation effects 
Dariusz Leszczynski in INDIA, September 15 -19, 2014
Leszczynski et al. 2002 
Caraglia et al. 2005 
Friedman et al. 2007 
Buttiglione et al. 2007 
Yu et al. 2008 
Lee et al. 2008 
Mechanism ?: Cell phone radiation affects stress response 
Cell proliferation and 
expression of cancer regularory genes
Scale of the potential problem 
Even if individual risk will be small, considering that there are over 6 billion of cell phone users, the burden for the society might be sizable in monetary and human suffering terms 
Radiation exposures from cell phones and from smart phones are not comparable –smart phone radiation exposures are much higher because of data traffic 
Dariusz Leszczynski in INDIA, September 15 -19, 2014
The IARC classification, of cell phone radiation as a possible carcinogen, invalidates the ICNIRP and WHO claims that the current safety standards protect all users. 
In three independent epidemiological case-control studies, two of which were evaluated by IARC, adult participants used regular, off-the-shelf, cell phones. 
These cell phones were built to fulfil all ICNIRP safety standards. 
However, avid use of such “safe” cell phones for period of over 10 years led to increased risk of brain cancer. 
This means that the current safety standards do not protect sufficiently users of cell phones and casts doubt whether safety standards for cell towers are reliable. 
Un-reliability of safety standards
Invoking the Precautionary Principle 
“WhetherornottoinvokethePrecautionaryPrincipleisadecisionexercisedwherescientificinformationisinsufficient, inconclusive,oruncertainandwherethereareindicationsthatthepossibleeffectsonenvironment,orhuman,animalorplanthealthmaybepotentiallydangerousandinconsistentwiththechosenlevelofprotection.” 
Dariusz Leszczynski in INDIA, September 15 -19, 2014
Invoking the Precautionary Principle 
•Scientificinformationisinsufficient,inconclusive,oruncertain 
•IARCclassificationaspossiblecarcinogen(2Bcategory) 
•Thereareindicationsthatthepossibleeffectsonhumanhealthmaybepotentiallydangerous 
•epidemiologicalstudiesfromInterphonegroupandfromHardellgroupshowincreasedbraincancerriskinlong-termavidusers 
•Inconsistentwiththechosenlevelofprotection 
•epidemiologicalstudiesshowingincreasedriskinlong-termavidusersweregeneratedbasedontheuseofregularcellphonesmeetingcurrentsafetystandards=currentsafetystandardsarebeinsufficienttoprotectusers 
Dariusz Leszczynski in INDIA, September 15 -19, 2014
India: problem of location of cell towers 
Dariusz Leszczynski in INDIA, September 15 - 19, 2014
Dariusz Leszczynski in INDIA, September 15 -19, 2014
•Cell phone app -runson any commercial Android phone 
•Measures RF emission exposure from cell phone, cell tower and wi-fi 
•Accurate algorithm to estimate total RF emission 
by Cellraid in Finland 
cellraid.com 
Dariusz Leszczynski in INDIA, September 15 -19, 2014
Dariusz Leszczynski in INDIA, September 15 -19, 2014
before 
now 
Cell tower radiation exposure in India 
Dariusz Leszczynski in INDIA, September 15 -19, 2014 
[drawings no to scale]
before 
now 
Cell phone radiation exposure 
lesser exposure 
of the users 
Dariusz Leszczynski in INDIA, September 15 -19, 2014
Conclusions 
•IARCclassificationofthecellphoneradiationasapossiblecarcinogenisasufficientreasonforinvokingPrecautionaryPrinciple 
•Claimsthatthecurrentsafetystandardsprotectallusersarenotsupportedbythescientificevidence 
•Currentsafetystandardsshouldbeurgentlyrevisedtobetterreflecttheavailablescience 
•Usersshouldbeinformedaboutthecurrentscientificuncertaintyandadvisedtolimitexposureswheneverpossibleandfeasibleandstronglydiscouragedfromkeepingcellphonesclosetobody(inpockets) 
Dariusz Leszczynski in INDIA, September 15 -19, 2014

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India September 2014

  • 1. CELL PHONES ANDCELL TOWERSHealth Risk and Precautionary Principle Dariusz Leszczynski,PhD, DSc Adjunct Professor, University of Helsinki Editor-in-Chief of Frontiers in Radiation and Health (specialty of the Frontiers in Public Health, Lausanne, Switzerland) Member of the Advisory Board, Cellraid, Ltd, Oulu, Finland Dariusz Leszczynski in INDIA, September 15 -19, 2014
  • 2. Who I am... few examples of my experience •Adjunct Professor at the University of Helsinki, Finland •Chief Editor of ’Radiation and Health’; specialty of Frontiers in Public Health •Two doctorates in biochemistry and in cell biology •22 years (1992-2013) at Finnish Radiation and Nuclear Safety Authority •2003-2007 as Head of Radiation Biology laboratory •2000-2013 as Research Professor •Assistant Professor at Harvard Medical School 1997-1999 •Guangbiao Professor at Zhejiang University, Hangzhou, China 2006-2009 •Visiting Professor at Swinburne University of Technology, Melbourne, Australia 2012/2013 •Testified in US Senate hearing on cell phones and health, in 2009 •Expert in IARC 2011 classification of carcinogenicity of cell phone radiation Dariusz Leszczynski in INDIA, September 15 -19, 2014
  • 3. WHO defintion of health “Healthisastateofcompletephysical,mentalandsocialwell-beingandnotmerelytheabsenceofdiseaseorinfirmity” WheneverdiscussingsafetyofradiationemittedbythewirelesscommunicationdevicesweneedtorememberthisWHOdefinitionofhealth Dariusz Leszczynski in INDIA, September 15 -19, 2014
  • 4. Safety standards –who sets? •Set by ICNIRP -International Commission on Non-Ionizing Radiation Protection •ICNIRP’s membership: by invitation only “private club” •Membership of ICNIRP based on similarity of scientific opinions of experts •No accountability for ICNIRP experts •Limited scientific debate when all ICNIRP members have a similar opinion •WHO EMF Project recommends use of ICNIRP safety standards •WHO EMF Project was started and run by former ICNIRP Chairman -Dr. Repacholi Dariusz Leszczynski in INDIA, September 15 -19, 2014
  • 5. ICNIRP sets safety standards WHO recommends to use ICNIRP safety standards In Finland Ministry considers WHO recommendation In Finland Ministry asks STUK opinion on ICNIRP standards STUK expert recommends use of ICNIRP standards STUK expert is ICNIRP member who prepared safety standards Setting safety standards in… Finland Dariusz Leszczynski in INDIA, September 15 -19, 2014
  • 6. Safety Standards –short-comings •Based on thermal effects of cell phone radiation •Not accounting for other parameters of exposure •Dosimetry based on macro-scale temperature changes •Lack of micro-scale dosimetry •Models do not resemble living cells and organs •Comparisons to classical heating do NOT apply Dariusz Leszczynski in INDIA, September 15 -19, 2014
  • 7. Macro-scale dosimetry Water Salt Sugar + = Problem: free movement of ions Dariusz Leszczynski in INDIA, September 15 -19, 2014
  • 8. Problems associated with the safety standards •No information whether/how cell phone radiation affects humans •No certainty that safety standards protect all users from anything besides thermal effects •Any equipment radiating below safety standards is considered safe which might be misleading •Compliance with safety standards is used as an excuse to stop research funding and to deploy new wireless technologies without any testing •Non-thermal effects exist but are refused to be studied in depth because of the “excuse” of safety standards Dariusz Leszczynski in INDIA, September 15 -19, 2014
  • 9. IARC evaluation may 2011 •30 invited experts divided into four sub-groups •Dosimetry •Epidemiology •Animal studies •Mechanistic laboratory in vitrostudies •Decissions done by consensus or by simple majority •The vast majority of experts voted for possible carcinogen classification Dariusz Leszczynski in INDIA, September 15 -19, 2014
  • 10. IARC 2011 and after IARC: Epidemiology •Interphone & Hardellstudies •no reliable exposure data •risk increase in long-term avid users •Children –only CEFALO •exposures for 2-4 years •has no statistical power to detect small risk •Trend-data -Little et al. 2012: slow rise of brain cancer cases in USA •trend is similar to Interphone “prediction” but not Hardell“prediction” •Danish Cohort update study –no effect but no exposure data at all •Million Women study -no effect but exposure data inadequate Dariusz Leszczynski in INDIA, September 15 -19, 2014
  • 11. The limited human evidence was based on the results of two sets of epidemiological studies European Interphone group and Hardellgroup in Sweden. After the IARC evaluation, in 2014, was published a new epidemiological study -the French CERENAT. The French study reached similar conclusions as Interphone and Hardellpreviously – long term avid use of cell phone increases a risk of developing brain cancer. It means that now there are three replications of the same epidemiological type of study, the case-control study, that all suggest cell phone radiation might increase a risk of brain cancer. After IARC evaluation: Epidemiology
  • 12. IARC 2011: Human studies •The vast majority are “feelings” studies •Subjects asked how they feel •Subject asked do they feel when radiation is on/off •EHS must exist –question is only of radiation cut-off level •Otherwise RF would be the only factor not causing individual sensitivity in people •Problem of EHS –studied by psychologists not physiologists –wrong methods •WHO definition of health –how to consider it? IARC classification justifies reasoning for “mental and social well-being” •Lack of studies examining biochemical responses of human tissues •Single skin proteomics study •Two studies examined glucose metabolism in the brain •That is all! Dariusz Leszczynski in INDIA, September 15 -19, 2014
  • 13. IARC 2011: Animal studies •No classical toxicology possible •By classical toxicology RF would be judged as harmful to humans •Not possible to overdose cell phone radiation because of heating effect •Life-time exposures to radiation doses similar to those emitted by cell phones show no effect –result useless for human health risk estimation •Co-carcinogen studies show some effects –cell phone radiation might potentiate effects of carcinogenic chemicals or radiation Dariusz Leszczynski in INDIA, September 15 -19, 2014
  • 14. *…but… what nobody is speaking about! Risk evaluation of radiation emitted by the base stations: scientific studies where exposure levels are similar to levels emitted by cell phones can be considered as toxicology studiesexamining effects of radiation emitted by base stations Dariusz Leszczynski in INDIA, September 15 -19, 2014
  • 15. IARC 2011: Mechanistic studies •Laboratory evidence was considered, by voting (no consensus) as insufficient to support/show mechanism of cell phone radiation effects Dariusz Leszczynski in INDIA, September 15 -19, 2014
  • 16. Leszczynski et al. 2002 Caraglia et al. 2005 Friedman et al. 2007 Buttiglione et al. 2007 Yu et al. 2008 Lee et al. 2008 Mechanism ?: Cell phone radiation affects stress response Cell proliferation and expression of cancer regularory genes
  • 17. Scale of the potential problem Even if individual risk will be small, considering that there are over 6 billion of cell phone users, the burden for the society might be sizable in monetary and human suffering terms Radiation exposures from cell phones and from smart phones are not comparable –smart phone radiation exposures are much higher because of data traffic Dariusz Leszczynski in INDIA, September 15 -19, 2014
  • 18. The IARC classification, of cell phone radiation as a possible carcinogen, invalidates the ICNIRP and WHO claims that the current safety standards protect all users. In three independent epidemiological case-control studies, two of which were evaluated by IARC, adult participants used regular, off-the-shelf, cell phones. These cell phones were built to fulfil all ICNIRP safety standards. However, avid use of such “safe” cell phones for period of over 10 years led to increased risk of brain cancer. This means that the current safety standards do not protect sufficiently users of cell phones and casts doubt whether safety standards for cell towers are reliable. Un-reliability of safety standards
  • 19. Invoking the Precautionary Principle “WhetherornottoinvokethePrecautionaryPrincipleisadecisionexercisedwherescientificinformationisinsufficient, inconclusive,oruncertainandwherethereareindicationsthatthepossibleeffectsonenvironment,orhuman,animalorplanthealthmaybepotentiallydangerousandinconsistentwiththechosenlevelofprotection.” Dariusz Leszczynski in INDIA, September 15 -19, 2014
  • 20. Invoking the Precautionary Principle •Scientificinformationisinsufficient,inconclusive,oruncertain •IARCclassificationaspossiblecarcinogen(2Bcategory) •Thereareindicationsthatthepossibleeffectsonhumanhealthmaybepotentiallydangerous •epidemiologicalstudiesfromInterphonegroupandfromHardellgroupshowincreasedbraincancerriskinlong-termavidusers •Inconsistentwiththechosenlevelofprotection •epidemiologicalstudiesshowingincreasedriskinlong-termavidusersweregeneratedbasedontheuseofregularcellphonesmeetingcurrentsafetystandards=currentsafetystandardsarebeinsufficienttoprotectusers Dariusz Leszczynski in INDIA, September 15 -19, 2014
  • 21. India: problem of location of cell towers Dariusz Leszczynski in INDIA, September 15 - 19, 2014
  • 22. Dariusz Leszczynski in INDIA, September 15 -19, 2014
  • 23. •Cell phone app -runson any commercial Android phone •Measures RF emission exposure from cell phone, cell tower and wi-fi •Accurate algorithm to estimate total RF emission by Cellraid in Finland cellraid.com Dariusz Leszczynski in INDIA, September 15 -19, 2014
  • 24. Dariusz Leszczynski in INDIA, September 15 -19, 2014
  • 25. before now Cell tower radiation exposure in India Dariusz Leszczynski in INDIA, September 15 -19, 2014 [drawings no to scale]
  • 26. before now Cell phone radiation exposure lesser exposure of the users Dariusz Leszczynski in INDIA, September 15 -19, 2014
  • 27. Conclusions •IARCclassificationofthecellphoneradiationasapossiblecarcinogenisasufficientreasonforinvokingPrecautionaryPrinciple •Claimsthatthecurrentsafetystandardsprotectallusersarenotsupportedbythescientificevidence •Currentsafetystandardsshouldbeurgentlyrevisedtobetterreflecttheavailablescience •Usersshouldbeinformedaboutthecurrentscientificuncertaintyandadvisedtolimitexposureswheneverpossibleandfeasibleandstronglydiscouragedfromkeepingcellphonesclosetobody(inpockets) Dariusz Leszczynski in INDIA, September 15 -19, 2014