5. PICO(S)
P : Patient or problem
I : Intervention (or risk factor, prognostic factor)
C : Control group (or absence of risk factor, progn.factor)
O : Outcome
(S): Study type
Categories: therapy, diagnosis, etiology, prognosis
6. Example 1
A 30 year old man attends the
emergency department after having
been bitten by a dog 4 hours
previously. He has puncture wounds
and a 1 cm laceration on his forearm.
His wounds are thoroughly cleaned and
a dressing has been applied.
Question: Do you need to prescribe
antibiotics?
7. PICO(S) example 1:
P = (adults with) dog bites
I = antibiotics
C = no antibiotics/ placebo
O = incidence of wound infection
S = randomized controlled trial
•Find search terms and synomyms for every section when needed
•Build your search strategy with Boolean operators
8. PICO(S) example 1:
T
• Dog bite antibiotics
• (dog OR dogs) AND (bite OR bites) AND
(antibiotic OR antibiotics OR penicillin)
10. Example 2
An 5 year-old child has crashed on his bicycle into a
car.
He suffers from abdominal pain, caused by his bike’s
handlebar which thumped into his abdomen.
Question: What is the value of a CT-scan compared
to echography in case of a child with blunt (non-
penetrating) abdominal trauma?
11. PICO(S) example 2
P = child blunt abdominal trauma
I = CT
C = echography
O = (diagnostic value)
(S) = (diagnostische studies)
12. Exercises Finding Best Evidence
1.
You are interested in the effectivity of interventions (such as
cognitive therapy) aimed at the prevention of major
depression recurrence/relapse.
P =
I =
C =
O =
Type of article:
13. Exercises Finding Best Evidence
2.
For adolescents with OCD (obsessive comp. Disorder),
which treatment is more effective to start with: cognitive
behaviour therapy, an anti-depressive agent (SSRI) or a
combination of both treatments?
P =
I =
C =
O =
Type of article:
14. Exercises Finding Best Evidence
3.
Many babies that are breastfed sleep regularly part of the
night in the bed of their parents. Since a couple of years this
is strongly discouraged in guidelines to prevent cot death
(Sudden Infant Death Syndrome). Can you find evidence
that sleeping between the parents is a risk factor for SIDS?
P =
I =
C =
O =
Type of article:
23. negative
limited to ISI journals
subject category dependent
Comparing IFs
Disadvantage specific research area
influence of “spikes”
Manipulation
IF does not say anything about individual
article
24. Other measures of impact
Journal Immediacy Index (ISI)
Journal Cited Half-Life/ Journal Citing Half-Life
EigenFactor & Article Inluence Score (ISI)
www.eigenfactor.org
SCImago Journal & Country Rank (Scopus)
www.scimagojr.com
25. Output scientists
bookchapters, thesis
patents
conference proceedings
articles in peer-reviewed journals
number of publicaties (in top 25%)
citations, citaties per article
Hirsch-index
27. Citation analyse
the number of publications
the number of publications in top 25%
(in relevant ISI-subject categories)
the number of citations
h-index
…
29. Databases for citation analysis
Web of Science– Thomson ISI
Scopus – Elsevier (no access anymore)
Access via CMB website:
http://www.rug.nl/umcg/library
Access to full text & databases from home:
Use your S-number or guest account
30. prof. dr. D.S. Postma
Web of Science (author search)
Postma DS: 587 hits
Excluded: meeting abstracts, notes, corrections
511 hits (=articles, reviews, editorials,
letters, proceeding papers)
31. prof. dr. D.S. Postma
Web of Science (advanced search)
#1 (AU=Postma DS) AND (OG=gron* OR
OG=beatr*) 529 hits
#2 AU=Postma D AND TS=(immu* OR asthma*
OR lung* OR resp* OR pulm*) AND (OG=gron*
OR OG=beatr*) 23 hits
#3 (#1 OR #2) 552 hits
Excluded: meeting abstracts, notes, corrections
480 hits (=articles, reviews, editorials,
letters, proceeding papers)
32. Difficult author names
Multiple initials
“Tussenvoegsels”, insertion
Name changes (marriage)
Common names
Voorbeeld: prof. P.E. de Jong
de Jong PE; Dejong PE; Jong PED; de Jong P
34. Publishing a lot is not rewarded,
but the publishing of
many higly-cited publications is!
35. Other interesting links
• Google Scholar http://Scholar.google.com
• Publish or Perish (PoP): http://www.harzing.com/pop.htm
• AltMetrics : alternative metrics for impact:
http://altmetrics.org/manifesto/
• 10 Ways to calculate your H-Index : free and otherwise
http://digicmb.blogspot.nl/2013/06/ways-to-calculate-your-h-
index-free-and.html
37. Exercise 1: Impact Factor
You are working on a systematic review on the prevention of obesity in
young children. You consider to send your your manuscript to the Int J
Pediatr Obes.
•What is the impact factor?
•Is it top25%?
•What are the ISI fields of this journal?
•What would be a good alternative (journal)?
38. Published papers by Simone Times Cites
paper 1 (2012) 0
Paper 2 (2012) 1
Paper 3 (2011) 3
Paper 4 (2010) 5
Paper 5 (2010) 1
Paper 6 (2010) 0
Paper 7 (2009) 15
Paper 8 (2008) 3
Exercise 2: h-index
A young researcher, Simone, has 8
publications. One of her papers, a review, has
been cited 15 times. The sum of the times cited
is 28.
What is the h-index of Simone?
39. Exercise 3: publication and citation overview
Prof. D. Postma is a respected researcher at the department of
Pulmonology.
Her initials are DS (Dirkje S. Postma).
•How many publications of prof. Postma (in combination with the
address field – Groningen) are found in WOS/WOK?
•What is the corresponding h-index?
Compare this to the number of publications in Scholar Google.
41. A little extra!
Make life easier!
Use Journal Apps to keep up with
the literature.
BrowZine | Docwise | Read by QxMD
Read more:
http://libguides.rug.nl/medicalEjournals
Notes de l'éditeur
P = dog bite I = antibiotics C = no antibiotics O = incidence wound infection PubMed: dog bite AND prophylactic AND antibiotics 37 hits Dog bites AND prophylactic AND antibiotics 38 hits dog bite* AND prophylactic AND antibiotics 34 hits dog bite AND prophyl* AND antibiotics 49 hits (dog bite OR dog bites) AND prophyl* AND antibiotics
Voorbeeld meer fundamenteel: Overzicht van de mechanismen die verantwoordelijk zijn voor chronische diffuse pijn bij fibromyalgie. Fibromyalgie - fibromyalgia Mechanismen - mechanisms/ pathophysiology (pain processing, pain pathways, central sensitization, comorbidities) Chronische (diffuse) pijn –pain Type te includeren studies/ LIMITS? Lastig afbakenen. PMID: 17502633 [PubMed - indexed for MEDLINE] Late-life depression is one of the main health problems among elderly populations and a key element of healthy ageing. Causal relationships of lifestyle- and diet-related factors in late-life depression are unclear. PMID:17975846
Voorbeeld meer fundamenteel: Overzicht van de mechanismen die verantwoordelijk zijn voor chronische diffuse pijn bij fibromyalgie. Fibromyalgie - fibromyalgia Mechanismen - mechanisms/ pathophysiology (pain processing, pain pathways, central sensitization, comorbidities) Chronische (diffuse) pijn –pain Type te includeren studies/ LIMITS? Lastig afbakenen. PMID: 17502633 [PubMed - indexed for MEDLINE] Late-life depression is one of the main health problems among elderly populations and a key element of healthy ageing. Causal relationships of lifestyle- and diet-related factors in late-life depression are unclear. PMID:17975846
P = dog bite I = antibiotics C = no antibiotics O = incidence wound infection PubMed: dog bite AND prophylactic AND antibiotics 37 hits Dog bites AND prophylactic AND antibiotics 38 hits dog bite* AND prophylactic AND antibiotics 34 hits dog bite AND prophyl* AND antibiotics 49 hits (dog bite OR dog bites) AND prophyl* AND antibiotics
Voorbeeld meer fundamenteel: Overzicht van de mechanismen die verantwoordelijk zijn voor chronische diffuse pijn bij fibromyalgie. Fibromyalgie - fibromyalgia Mechanismen - mechanisms/ pathophysiology (pain processing, pain pathways, central sensitization, comorbidities) Chronische (diffuse) pijn –pain Type te includeren studies/ LIMITS? Lastig afbakenen. PMID: 17502633 [PubMed - indexed for MEDLINE] Late-life depression is one of the main health problems among elderly populations and a key element of healthy ageing. Causal relationships of lifestyle- and diet-related factors in late-life depression are unclear. PMID:17975846