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When you see beyond
     monitors..
The Diagnosis errors and Diagnosis game
            Ahmad Abou Leila
         PGY5 –Anesthesiology
       American University of Beirut

                Ahmad M. Abou Leila
Take our monitoring skills to the next level.
1




           Integrate the clinical skills with the monitoring
    2      skills


                      Why we do Diagnosis errors?
            3




                                How to avoid the Dx errors
                  4




                 Ahmad M. Abou Leila
Making Diagnosis errors




                          Ahmad M. Abou Leila
Common
 Ahmad M. Abou Leila
Common
  Ahmad M. Abou Leila
Ahmad M. Abou Leila
Ahmad M. Abou Leila
Ahmad M. Abou Leila
Ahmad M. Abou Leila
Cognitive
 Errors




            Ahmad M. Abou Leila
Ahmad M. Abou Leila
Perception errors
                    Ahmad M. Abou Leila
When you separate patients from the monitor

              Ahmad M. Abou Leila
Numbers are meaningless without patients




                                     72 y/o              20y/o
         BP100/52                (Hypotension)         (normal)




                                 Ahmad M. Abou Leila
VPB

Renal failure
Massive transfusion,
SUX in Bed ridden

   Check the electrolytes and management




                   Ahmad M. Abou Leila
VPB
Healthy patients during left lobectomy

         Cautery irritation




                 Ahmad M. Abou Leila
Patient A                                   Patient B
    PaCO2=40                                    PaCO2=40


Discharged to floor                         Respiratory Acidosis




                      Ahmad M. Abou Leila
Patient B:
pregnant woman

After 38 weeks
PaCO2 <30



                 Ahmad M. Abou Leila
Ahmad M. Abou Leila
Regular craniotomy    Pituitary surgery                  TBI

   Mannitol Therapy    Diabetes insipidus         Cerebral salt wasting




                            Ahmad M. Abou Leila
Normal Na          Hypernatremia                Hponatermia


Mannitol Therapy   Diabetes insipidus         Cerebral salt wasting




                        Ahmad M. Abou Leila
Ahmad M. Abou Leila
Positive test Dose




 Healthy surgical
     patients
   HR > 20BPM
  BP >15 mmHg
T wave amplitude
    decrease

                          Ahmad M. Abou Leila
Processing Errors
     Ahmad M. Abou Leila
Availability bias
 “Dx according to what available
           in our Brain
Less available pathology less Dx”


     Representativeness                                   Confirmation Bias
  “miss the atypical features”



       outcome bias
   “choosing Dx with good           Premature closure
 outcomes avoid dx with bad
         outcome”



     Overconfidence Bias                                     Diagnosis
                                                            momentum




                                    Ahmad M. Abou Leila
Obese patient ..Lap chole..




Post operative he developed tachycardia and hypotension




                   JP drain ZERO ..




            He was Treated as hypovolemic
                (voluven,blood,Aline)


                    Ahmad M. Abou Leila
Ahmad M. Abou Leila
Availability bias
                                                    We see a lot of hypovolemia …ready
                                                          available in our minds



                                                          Out come bias
Obese patient ..Lap chole..                     Hypovolemia better prognosis than PE


Post operative he developed
tachycardia and hypotension
                                                            It is Hypovolemia
                                                            Premature closure
     JP drain ZERO ..

    He was Treated as
       hypovolemic                             Insert A-line and volume administration
   (voluven,blood..etc)                         Confirmation Bias and Dx momentum




                                                                  Death
                              Ahmad M. Abou Leila
After Spinal anesthesia in asthmatic patient

Patient become Dyspneic and desaturation


        The resident explanation

           “it is false reading”



                  Ahmad M. Abou Leila
Patient Turned Blue…and again …




        Ahmad M. Abou Leila
Ahmad M. Abou Leila
“it is false reading”


premature closure..




      Ahmad M. Abou Leila
38 y/o female patient
     Preclampsia…
     C/S under GA…
     Everything is fine




Post Operative she developed severe Dyspnea


     What is your differential ?




                                    Ahmad M. Abou Leila
Pulmonary embolism
           Aspiration
  Tocolytic pulmonary edema
Pre-eclampsia Pulmonary edema
             Anxiety



           Ahmad M. Abou Leila
Not every Postoperative Nausea…..Do EGK to rule out MI

Never get the habit of MED student after Brugada lesson
      Every ST elevation has to rule out brugada



                 Base-rate neglect Bias
 the tendency to ignore the true prevalence of a disease
         Tendency to Diagnose “exotic “ things




                        Ahmad M. Abou Leila
To write goo differential list ..you have to answer three questions


                                   Ahmad M. Abou Leila
What is the most common cause?




What is the most serious cause?




 What is the most likely cause?




      Ahmad M. Abou Leila
Ahmad M. Abou Leila
What is the most common                  Hpovolemia(bleeding)
          cause?                          Epidural anesthesia




                                          Pulmonary embolism
 What is the most serious
                                            Mediastinal shift
          cause?




                   What is the most likely cause?




                        Ahmad M. Abou Leila
Ahmad M. Abou Leila
Mediastinal shift

Clamp the Drain…….
allow the air to fill the cavity
call for Surgeon




                                   Ahmad M. Abou Leila
56 y/o female patient osteoperosis,otherwise
                        healthy…
    Kyphoplasty…interventional radiology..LA+sedation
                     PACU Dyspnea




Ahmad M. Abou Leila
Ahmad M. Abou Leila
Pulmonary cement embolism After vertebroplasty
               Ahmad M. Abou Leila
Ahmad M. Abou Leila
What is the most common
                                              Opioid overdose
          cause?




 What is the most serious                       Pontine hge
          cause?




                   What is the most likely cause?




                        Ahmad M. Abou Leila
Most likely ..organopphosprous poisoning




       SUXMETHONIUM is CI


              Ahmad M. Abou Leila
During transfer of TOF baby after DX cardiac CATH



                Baby become cyanotic and saturation dropped to 60




Baby had normal breathing pattern(no labored breathing or obstruction)




                  Ahmad M. Abou Leila
Ahmad M. Abou Leila
I gave the baby oxygen..but he still blue




                                Ahmad M. Abou Leila
Ahmad M. Abou Leila
Least likely cause of this desaturation




    Most likely cause of cynosis
            (TET spells)




                             Ahmad M. Abou Leila
Photo from the BLOG




                      Ahmad M. Abou Leila
Ahmad M. Abou Leila
Ahmad M. Abou Leila
After CSE for Multigravida patient
the OB resident informed you that
      there is significant FHR
        abnormalities …..

         What you think ?

Patient Placed Right side up and BP
             normal…

        Still FHR abnormal

         What you think ?
   Rule out Uterine Hypertonus




                                      Ahmad M. Abou Leila
Logistic regression analysis showed the type of analgesia
as the only independent predictor of uterine hypertonus
(odds ratio 3.526, 95% confidence interval 1.21-10.36; P=.022).

Combined spinal-epidural analgesia
is associated with a significantly greater incidence of FHR abnormalities
 related to uterine hypertonus compared with epidural analgesia



                               Ahmad M. Abou Leila
Deficient Knowledge
                      Ahmad M. Abou Leila
When heart Pumps Blood into the vessels

                                     Ahmad M. Abou Leila
Vascular system is not straight line …..




                                 Ahmad M. Abou Leila
Vascular system is highly branched system. .with many branches and bifurcations

                                 Ahmad M. Abou Leila
Ahmad M. Abou Leila
A-line tracing in elderly

                   Ahmad M. Abou Leila
A-line tracing in young

                  Ahmad M. Abou Leila
Appear during Vasoconstriction

                                 Ahmad M. Abou Leila
Combination of two waves…
Higher wave amplitude




                Ahmad M. Abou Leila
Aorta



                                             Brachial artery




   As you go Further
  Pulse amplification
  Taller systolic peak
Lower diastolic pressure




                                                               Dorsalis pedis

                           Ahmad M. Abou Leila
Measured SBP in       In Shock
 radial and DP    Vasoconstriction
                                             False sense of
  Is 20mmHg       Peripheral pulse
                                                security
  higher than       Higher then
 central Aorta         central




                       Ahmad M. Abou Leila
Systolic pressure monitoring




    Reflects            Not               Change with site                 Not
                     blood flow       Peripheral augmentation   related to autoregulation
initial upstroke




                                  Ahmad M. Abou Leila
CPP                MAP-ICP


 SVR               MAP-CVP/CO



coronary        Diastolic pressure-LVEDP



Abdomen             MAP-IAP


     Systolic Blood pressure didn’t appear in autoregulation

                         Ahmad M. Abou Leila
Mean Arterial Blood Pressure


           MAP   Indicator of blood flow


           MAP   Main Determinants of autoregulation


                 Not affected by Reflected waves
           MAP
                 No peripheral augmentation


                 Not affected by over Damping and
           MAP
                 underdamping




                             Ahmad M. Abou Leila
Lowest MAP without
                          hypoperfusion

                            Severe HTN :65

MAP                         Treated HTN:53
                              Normal :43




      Ahmad M. Abou Leila
Ahmad M. Abou Leila
Better Together
         Ahmad M. Abou Leila
Ahmad M. Abou Leila
Ahmad M. Abou Leila
Ahmad M. Abou Leila
bisferiens pulse




    initial peak upstroke from rapid left ventricular ejection in
    early systole


Ahmad M. Abou Leila
Ahmad M. Abou Leila
Ahmad M. Abou Leila
Pulsus alternan…..Not related to MV
          Ahmad M. Abou Leila
Severe vasoconstriction
          Elevated DP
          Multiple RW
Slow up rise of systolic pressure




            Ahmad M. Abou Leila
Ahmad M. Abou Leila
Ahmad M. Abou Leila
Severe AS and Severe
Severe AR   HOCM                         IABP
                                                         AR

                   Ahmad M. Abou Leila
Ahmad M. Abou Leila
Ahmad M. Abou Leila
In Aline leveling is not a problem but in CVP is
           CVP is very small number




                  Ahmad M. Abou Leila
Ahmad M. Abou Leila
Accurate Zeroing




  Ahmad M. Abou Leila
Accurate Zeroing




  Ahmad M. Abou Leila
Ahmad M. Abou Leila
1
Injection of cold saline




                                                                 Measure the
                                                          3
                                                              Temperature change




      Entrance of cold saline   2




                                    Ahmad M. Abou Leila
Ahmad M. Abou Leila
Ahmad M. Abou Leila
Ahmad M. Abou Leila
Ahmad M. Abou Leila
Ahmad M. Abou Leila
Ahmad M. Abou Leila
Ahmad M. Abou Leila
U will not see the regular atrial Pressure wave in the severe tricuspid regurge
U will have VENTRICULIZATION of ATRIA


                            Ahmad M. Abou Leila
Ahmad M. Abou Leila
Ahmad M. Abou Leila
SVO2=SaO2-(VO2/COx1.36xHct) X 100




            Ahmad M. Abou Leila
Venous oximetry




 Venous oximetry detects organs
hypoperfusion (VO2)before organs
       ischemia develop

  Reduced venous oxygen saturation
   better predicts adverse outcome
    after cardiac surgery than does
             cardiac output
        Ahmad M. Abou Leila
It is toooooooooooooooooo complicated
Any thing else instead
           Ahmad M. Abou Leila
Oxygen saturation in the central line




                    ScVO2 is lower SVO2 by
                            2%-3%
                         ScVO2 =SVC                SVO2=SVC+IVC
    SVC sampling     Brain consumption is         IVC more oxygen
     Central line     higher than rest of            SVO2 more
                      body…SVC less O2
                          ScVO2 less
                            Ahmad M. Abou Leila
Ahmad M. Abou Leila
Current evidence and consensus-based guideline for monitoring and
treatment of cardiac surgery patients during the postoperative period in
                         ICU recommends an
                             ScvO2 > 70%
                              SvO2 > 65%




                          Ahmad M. Abou Leila
ScVO2    European Multicenter study
  73     Critical care 2006,10 R185


                  Deflaviis et al
        ScVO2
         >70      Minerva anesthesiology 2006



                ScVO2      Pearse et al
                  75       Critical care 2009,9 R694-699


                        SVO2           Polonen et al
                         >70           Anes-Analgesia 2000,90:1052-1059




                        Ahmad M. Abou Leila
Why venous oximetry?
60% of patient udergoing major surgeries
develop intestinal ischemia
SVO2 or ScVO2 directed therapy associated
with less postoperative complications and
mortality
Small increase with SVO2 associated with
significant decrease in the mortality




   Ahmad M. Abou Leila
ACT monitoring




             Ahmad M. Abou Leila
Ahmad M. Abou Leila
ACT contact activator
Celite
Kaolin




            Ahmad M. Abou Leila
Aprotonin inhibit
Celite




            Ahmad M. Abou Leila
Prolonged ACT
Sub optimal heparin




          Ahmad M. Abou Leila
Kaolin containing should be used




                 Ahmad M. Abou Leila
Muscle relaxants monitoring




          Ahmad M. Abou Leila
Tests to assess
   recovery




    Tests to assess
        Depth


                      Ahmad M. Abou Leila
TOF%        30           40            50              60         70     80   90
Head lift
 5sec
 Tongue
Depressor
   test

  V or T       Fade
   TOF       detection


  V or T
   DBS
                                Fade detection                                        Safe
                                                                                   extubation
  50 HZ       Fade                                                                     No
 Tetanus    detection
                                                                                    residual
 100 HZ
                                                                                    paralysis
                                                 Fade detect
 Tetanus



                              Always Use quantitative test



                                                   Ahmad M. Abou Leila
TOF%   30   40                         50                     60                  70     80   90




                                                                                                      Safe
                                                                                                   extubation
                                                                                                       No
                                                                                                    residual
                                                                                                    paralysis




            Debaene B, Plaud B, Dilly MP, Donati F. Residual paralysis in
            the PACU after a single intubating dose of nondepolarizing
            muscle relaxant with an intermediate durationAhmad M.
                                                           of action.       Abou Leila
            Anesthesiology 2003;98:1042–8
TOF%   30   40   50        60                         70                       80   90




                                                                                            Safe
                                                                                         extubation
                                                                                             No
                                                                                          residual
                                                                                          paralysis




                      AhmadReversaltooffour hoursLeilasingle intubating dose
                       Caldwell JE.
                                    M. residual neuromuscular block with
                       neostigmine at one Abou after a
                       of vecuronium. Anesth Analg 1995;80:1168–74
Patient A Co-oximetry results




                                                       What will be the SPO2
 Oxy Hb     70%
                                                        reading in these two
 Reduced Hb 10 %
 Carboxy Hb 20%                                              patients?
                                                           Both SPO2= 90
                                                      SPO2 reads only oxy and
                                                              reduced
                                                     And reads the COHB as Oxy
   Patient B Co-oximetry results                                 HB




Oxy Hb     50%
Reduced Hb 10 %
Carboxy Hb 40%



                               Ahmad M. Abou Leila
Oxygen saturation Gap
     SPO2-SaO2
       OSG<5




           Ahmad M. Abou Leila
Oxygen saturation Gap
          SPO2-SaO2>5
Abnormal Hb not measured by SPO2




                Ahmad M. Abou Leila
Link the monitor data to the patient physiology…number alone are meaningless

Before you make your diagnoses ASK your self” what else might this be?” what did I miss”

Remember the three questions “the Most common” ”The most dangerous” and the most likely”

Don’t be overconfident…ask for feedback

The most important ting to improve your Diagnosing skills is

Read and practice




                                         Ahmad M. Abou Leila
Ahmad M. Abou Leila
Have a nice day




Ahmad M. Abou Leila

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When you read beyond the monitor share version

  • 1. When you see beyond monitors.. The Diagnosis errors and Diagnosis game Ahmad Abou Leila PGY5 –Anesthesiology American University of Beirut Ahmad M. Abou Leila
  • 2. Take our monitoring skills to the next level. 1 Integrate the clinical skills with the monitoring 2 skills Why we do Diagnosis errors? 3 How to avoid the Dx errors 4 Ahmad M. Abou Leila
  • 3. Making Diagnosis errors Ahmad M. Abou Leila
  • 4. Common Ahmad M. Abou Leila
  • 5. Common Ahmad M. Abou Leila
  • 10. Cognitive Errors Ahmad M. Abou Leila
  • 11. Ahmad M. Abou Leila
  • 12. Perception errors Ahmad M. Abou Leila
  • 13. When you separate patients from the monitor Ahmad M. Abou Leila
  • 14. Numbers are meaningless without patients 72 y/o 20y/o BP100/52 (Hypotension) (normal) Ahmad M. Abou Leila
  • 15. VPB Renal failure Massive transfusion, SUX in Bed ridden Check the electrolytes and management Ahmad M. Abou Leila
  • 16. VPB Healthy patients during left lobectomy Cautery irritation Ahmad M. Abou Leila
  • 17. Patient A Patient B PaCO2=40 PaCO2=40 Discharged to floor Respiratory Acidosis Ahmad M. Abou Leila
  • 18. Patient B: pregnant woman After 38 weeks PaCO2 <30 Ahmad M. Abou Leila
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  • 20. Regular craniotomy Pituitary surgery TBI Mannitol Therapy Diabetes insipidus Cerebral salt wasting Ahmad M. Abou Leila
  • 21. Normal Na Hypernatremia Hponatermia Mannitol Therapy Diabetes insipidus Cerebral salt wasting Ahmad M. Abou Leila
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  • 23. Positive test Dose Healthy surgical patients HR > 20BPM BP >15 mmHg T wave amplitude decrease Ahmad M. Abou Leila
  • 24. Processing Errors Ahmad M. Abou Leila
  • 25. Availability bias “Dx according to what available in our Brain Less available pathology less Dx” Representativeness Confirmation Bias “miss the atypical features” outcome bias “choosing Dx with good Premature closure outcomes avoid dx with bad outcome” Overconfidence Bias Diagnosis momentum Ahmad M. Abou Leila
  • 26. Obese patient ..Lap chole.. Post operative he developed tachycardia and hypotension JP drain ZERO .. He was Treated as hypovolemic (voluven,blood,Aline) Ahmad M. Abou Leila
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  • 28. Availability bias We see a lot of hypovolemia …ready available in our minds Out come bias Obese patient ..Lap chole.. Hypovolemia better prognosis than PE Post operative he developed tachycardia and hypotension It is Hypovolemia Premature closure JP drain ZERO .. He was Treated as hypovolemic Insert A-line and volume administration (voluven,blood..etc) Confirmation Bias and Dx momentum Death Ahmad M. Abou Leila
  • 29. After Spinal anesthesia in asthmatic patient Patient become Dyspneic and desaturation The resident explanation “it is false reading” Ahmad M. Abou Leila
  • 30. Patient Turned Blue…and again … Ahmad M. Abou Leila
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  • 32. “it is false reading” premature closure.. Ahmad M. Abou Leila
  • 33. 38 y/o female patient Preclampsia… C/S under GA… Everything is fine Post Operative she developed severe Dyspnea What is your differential ? Ahmad M. Abou Leila
  • 34. Pulmonary embolism Aspiration Tocolytic pulmonary edema Pre-eclampsia Pulmonary edema Anxiety Ahmad M. Abou Leila
  • 35. Not every Postoperative Nausea…..Do EGK to rule out MI Never get the habit of MED student after Brugada lesson Every ST elevation has to rule out brugada Base-rate neglect Bias the tendency to ignore the true prevalence of a disease Tendency to Diagnose “exotic “ things Ahmad M. Abou Leila
  • 36. To write goo differential list ..you have to answer three questions Ahmad M. Abou Leila
  • 37. What is the most common cause? What is the most serious cause? What is the most likely cause? Ahmad M. Abou Leila
  • 38. Ahmad M. Abou Leila
  • 39. What is the most common Hpovolemia(bleeding) cause? Epidural anesthesia Pulmonary embolism What is the most serious Mediastinal shift cause? What is the most likely cause? Ahmad M. Abou Leila
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  • 41. Mediastinal shift Clamp the Drain……. allow the air to fill the cavity call for Surgeon Ahmad M. Abou Leila
  • 42. 56 y/o female patient osteoperosis,otherwise healthy… Kyphoplasty…interventional radiology..LA+sedation PACU Dyspnea Ahmad M. Abou Leila
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  • 44. Pulmonary cement embolism After vertebroplasty Ahmad M. Abou Leila
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  • 46. What is the most common Opioid overdose cause? What is the most serious Pontine hge cause? What is the most likely cause? Ahmad M. Abou Leila
  • 47. Most likely ..organopphosprous poisoning SUXMETHONIUM is CI Ahmad M. Abou Leila
  • 48. During transfer of TOF baby after DX cardiac CATH Baby become cyanotic and saturation dropped to 60 Baby had normal breathing pattern(no labored breathing or obstruction) Ahmad M. Abou Leila
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  • 50. I gave the baby oxygen..but he still blue Ahmad M. Abou Leila
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  • 52. Least likely cause of this desaturation Most likely cause of cynosis (TET spells) Ahmad M. Abou Leila
  • 53. Photo from the BLOG Ahmad M. Abou Leila
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  • 56. After CSE for Multigravida patient the OB resident informed you that there is significant FHR abnormalities ….. What you think ? Patient Placed Right side up and BP normal… Still FHR abnormal What you think ? Rule out Uterine Hypertonus Ahmad M. Abou Leila
  • 57. Logistic regression analysis showed the type of analgesia as the only independent predictor of uterine hypertonus (odds ratio 3.526, 95% confidence interval 1.21-10.36; P=.022). Combined spinal-epidural analgesia is associated with a significantly greater incidence of FHR abnormalities related to uterine hypertonus compared with epidural analgesia Ahmad M. Abou Leila
  • 58. Deficient Knowledge Ahmad M. Abou Leila
  • 59. When heart Pumps Blood into the vessels Ahmad M. Abou Leila
  • 60. Vascular system is not straight line ….. Ahmad M. Abou Leila
  • 61. Vascular system is highly branched system. .with many branches and bifurcations Ahmad M. Abou Leila
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  • 63. A-line tracing in elderly Ahmad M. Abou Leila
  • 64. A-line tracing in young Ahmad M. Abou Leila
  • 65. Appear during Vasoconstriction Ahmad M. Abou Leila
  • 66. Combination of two waves… Higher wave amplitude Ahmad M. Abou Leila
  • 67. Aorta Brachial artery As you go Further Pulse amplification Taller systolic peak Lower diastolic pressure Dorsalis pedis Ahmad M. Abou Leila
  • 68. Measured SBP in In Shock radial and DP Vasoconstriction False sense of Is 20mmHg Peripheral pulse security higher than Higher then central Aorta central Ahmad M. Abou Leila
  • 69. Systolic pressure monitoring Reflects Not Change with site Not blood flow Peripheral augmentation related to autoregulation initial upstroke Ahmad M. Abou Leila
  • 70. CPP MAP-ICP SVR MAP-CVP/CO coronary Diastolic pressure-LVEDP Abdomen MAP-IAP Systolic Blood pressure didn’t appear in autoregulation Ahmad M. Abou Leila
  • 71. Mean Arterial Blood Pressure MAP Indicator of blood flow MAP Main Determinants of autoregulation Not affected by Reflected waves MAP No peripheral augmentation Not affected by over Damping and MAP underdamping Ahmad M. Abou Leila
  • 72. Lowest MAP without hypoperfusion Severe HTN :65 MAP Treated HTN:53 Normal :43 Ahmad M. Abou Leila
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  • 74. Better Together Ahmad M. Abou Leila
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  • 78. bisferiens pulse initial peak upstroke from rapid left ventricular ejection in early systole Ahmad M. Abou Leila
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  • 81. Pulsus alternan…..Not related to MV Ahmad M. Abou Leila
  • 82. Severe vasoconstriction Elevated DP Multiple RW Slow up rise of systolic pressure Ahmad M. Abou Leila
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  • 85. Severe AS and Severe Severe AR HOCM IABP AR Ahmad M. Abou Leila
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  • 88. In Aline leveling is not a problem but in CVP is CVP is very small number Ahmad M. Abou Leila
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  • 90. Accurate Zeroing Ahmad M. Abou Leila
  • 91. Accurate Zeroing Ahmad M. Abou Leila
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  • 93. 1 Injection of cold saline Measure the 3 Temperature change Entrance of cold saline 2 Ahmad M. Abou Leila
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  • 101. U will not see the regular atrial Pressure wave in the severe tricuspid regurge U will have VENTRICULIZATION of ATRIA Ahmad M. Abou Leila
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  • 104. SVO2=SaO2-(VO2/COx1.36xHct) X 100 Ahmad M. Abou Leila
  • 105. Venous oximetry Venous oximetry detects organs hypoperfusion (VO2)before organs ischemia develop Reduced venous oxygen saturation better predicts adverse outcome after cardiac surgery than does cardiac output Ahmad M. Abou Leila
  • 106. It is toooooooooooooooooo complicated Any thing else instead Ahmad M. Abou Leila
  • 107. Oxygen saturation in the central line ScVO2 is lower SVO2 by 2%-3% ScVO2 =SVC SVO2=SVC+IVC SVC sampling Brain consumption is IVC more oxygen Central line higher than rest of SVO2 more body…SVC less O2 ScVO2 less Ahmad M. Abou Leila
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  • 109. Current evidence and consensus-based guideline for monitoring and treatment of cardiac surgery patients during the postoperative period in ICU recommends an ScvO2 > 70% SvO2 > 65% Ahmad M. Abou Leila
  • 110. ScVO2 European Multicenter study 73 Critical care 2006,10 R185 Deflaviis et al ScVO2 >70 Minerva anesthesiology 2006 ScVO2 Pearse et al 75 Critical care 2009,9 R694-699 SVO2 Polonen et al >70 Anes-Analgesia 2000,90:1052-1059 Ahmad M. Abou Leila
  • 111. Why venous oximetry? 60% of patient udergoing major surgeries develop intestinal ischemia SVO2 or ScVO2 directed therapy associated with less postoperative complications and mortality Small increase with SVO2 associated with significant decrease in the mortality Ahmad M. Abou Leila
  • 112. ACT monitoring Ahmad M. Abou Leila
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  • 114. ACT contact activator Celite Kaolin Ahmad M. Abou Leila
  • 115. Aprotonin inhibit Celite Ahmad M. Abou Leila
  • 116. Prolonged ACT Sub optimal heparin Ahmad M. Abou Leila
  • 117. Kaolin containing should be used Ahmad M. Abou Leila
  • 118. Muscle relaxants monitoring Ahmad M. Abou Leila
  • 119. Tests to assess recovery Tests to assess Depth Ahmad M. Abou Leila
  • 120. TOF% 30 40 50 60 70 80 90 Head lift 5sec Tongue Depressor test V or T Fade TOF detection V or T DBS Fade detection Safe extubation 50 HZ Fade No Tetanus detection residual 100 HZ paralysis Fade detect Tetanus Always Use quantitative test Ahmad M. Abou Leila
  • 121. TOF% 30 40 50 60 70 80 90 Safe extubation No residual paralysis Debaene B, Plaud B, Dilly MP, Donati F. Residual paralysis in the PACU after a single intubating dose of nondepolarizing muscle relaxant with an intermediate durationAhmad M. of action. Abou Leila Anesthesiology 2003;98:1042–8
  • 122. TOF% 30 40 50 60 70 80 90 Safe extubation No residual paralysis AhmadReversaltooffour hoursLeilasingle intubating dose Caldwell JE. M. residual neuromuscular block with neostigmine at one Abou after a of vecuronium. Anesth Analg 1995;80:1168–74
  • 123. Patient A Co-oximetry results What will be the SPO2 Oxy Hb 70% reading in these two Reduced Hb 10 % Carboxy Hb 20% patients? Both SPO2= 90 SPO2 reads only oxy and reduced And reads the COHB as Oxy Patient B Co-oximetry results HB Oxy Hb 50% Reduced Hb 10 % Carboxy Hb 40% Ahmad M. Abou Leila
  • 124. Oxygen saturation Gap SPO2-SaO2 OSG<5 Ahmad M. Abou Leila
  • 125. Oxygen saturation Gap SPO2-SaO2>5 Abnormal Hb not measured by SPO2 Ahmad M. Abou Leila
  • 126. Link the monitor data to the patient physiology…number alone are meaningless Before you make your diagnoses ASK your self” what else might this be?” what did I miss” Remember the three questions “the Most common” ”The most dangerous” and the most likely” Don’t be overconfident…ask for feedback The most important ting to improve your Diagnosing skills is Read and practice Ahmad M. Abou Leila
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  • 128. Have a nice day Ahmad M. Abou Leila