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Intermittent periods of feed deprivation can induce damage to the gastric squamous epithelium within hours to days, as a result of increased gastric acidity. We used the protocol below: DAY 1 DAY 2 DAY 3 DAY 4 DAY 5 DAY 6 DAY 7 HAY NO YES NO YES NO YES NO Bleeding gastric squamous mucosal ulcers can occur in as short as forty-eight hours. There are different stages and degrees of damage to the gastric squamous epithelium with exposure to excessive acidity. The earliest endoscopically observed change is a reddening of the epithelium. Longer duration of exposure to acid results in loss of epithelial layers. Epithelial loss may extend to the basal epithelial cells (erosion), or extend into the lamina propria (ulcer). Within 24 to 48 hours of erosion/ulcer formation, capillary congestion, increased numbers of capillaries (angiogenesis), neutrophilic infiltration, and epithelial hyperplasia can be seen. These processes promote healing and are stimulated by peptic epithelial injury. Concurrent treatment with ranitidine prevents these lesions from forming.