Introduction of metabolism

•

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Dr Muhammad Mustansar

Introduction to Metabolism

Mutienzyme complex
Separate
enzymes

Membrane
Bound System

ORGANIZATION OF
PATHWAYS
Closed Loop
(intermediates recycled)

Linear
(product of rxns are
substrates for
subsequent rxns)

Spiral
(same set of enzymes
used repeatedly)

METABOLIS
M
PROCEEDS
IN
DISCRETE
STEPS

ENZYME REGULATION OF
FLUX
Common mechanisms

Feedforward activation

ATP

PHOSPHORYL-GROUP
TRANSFER

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Introduction of metabolism

1.

2. Introduction to Metabolism

3.

4.

5.

6. Mutienzyme complex Separate enzymes Membrane Bound System

7. ORGANIZATION OF PATHWAYS Closed Loop (intermediates recycled) Linear (product of rxns are substrates for subsequent rxns) Spiral (same set of enzymes used repeatedly)

8. METABOLIS M PROCEEDS IN DISCRETE STEPS

9. ENZYME REGULATION OF FLUX Common mechanisms Feedforward activation

10.

11.

13.

14.

15. PHOSPHORYL-GROUP TRANSFER