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Cavernous Sinus


        By
Dr. Noura El Tahawy
Position & Extension

-on the side of the body of sphenoid,
-extending from the apex of the petrous temporal bone (behind)
to the medial end of the superior orbital fissure (in front).
-Each sinus is 2 cm long and 1 cm wide,
Relations
* Medially:
• Sphenoidal air sinus.
• Hypophysis cerebri.

* Laterally:
• Trigeminal ganglion.
• Uncus of the temporal lobe.

*   Nerves in its lateral wall: (from above downwards)
•   Oculomotor nerve.
•   Trochlear nerve.
•   Ophthalmic division of trigeminal nerve.
•   Maxillary division of trigeminal nerve.

* Structures within its cavity.
• Internal carotid artery.
• Abducent nerve (on the lateral side of the artery).
• -carotid sympathetic plexus
• N.B.: The internal carotid artery may rupture inside the cavernous sinus due to
  fracture base of the skull. This results in a pulsating swelling behind the orbit.
Coronal section of the cavernous sinus.
Cavernous sinus.
Cavernous Sinuses
       Optic Chiasma

Internal Carotid Artery




                    Uncus
                      of                Pituitary
   Sphenoidal    Temporal Lobe           Gland
    Air Sinus


                                       Sphenoidal
                                       AirSinuses




      Body
       of
  Sphenoid Bone
Medial end of
The superior orbital fissure




                                Uncus

                                         Optic Chaisma


             Temporal lobe




                                         Apex of petrous

                   Trigeminal Ganglion
Content of the Cavernous Sinuses

Occulomotor Nerve




Trochlear Nerve



Ophthalmic Nerve



Maxillary Nerve




                                 Internal carotid Artery
             Abducent Nerve                with
                                   Sympathetic Plexus
Tributaries and
communications
Anteriorly:
•   Ophthalmic veins (connect it with the facial vein in the face).
•   Sphenoparietal sinus.

Posteriorly:
•   Superior petrosal sinus (connects it with the transverse sinus).
•   Inferior petrosal sinus (connects it with the internal jugular vein).

Medially:
•   Anterior and posterior intercavernous sinuses (connect the 2cavernous sinuses together).

Superiorly:
•   Superficial middle cerebral vein (from the lateral surface of the
•   brain).
•   Cerebral veins from the inferior surface of the brain.

Inferiorly:
•   Emissary vein through the carotid canal (connects it with the internal jugular vein).
•   Emissary vein through the foramen ovale (connects it with the pterygoid plexus of
    veins).
Superior and inferior
                    Ophthalmic veins



                  Plexus of emissary veins through
                 carotid canal to internal jugular vein




   inferior
Petrosal sinus
Tributaries of Cavernous Sinus

Anteriorly, Posteriorly, Medially and Superiorly
In
                  fe                                   Ce
                           rio
                                                                                                                                                                     Cerebral vein
                                                         nt
                               ro                      th ral
                                                                                                                                                                   Superficial middle


       Su
            pe                     ph                    e ve
                                       th                  re in




                                                                                             Sphenoparietal sinus
               r io                       al                 tin o
                    ro                      m                   a f
                        ph                    ic
                            th                   ve
                               al                   in
                                  m
Su                                  ic
    pe                                  ve
        r io                               in
             ro
                ph
                     th
                                                                                                                       Ri

                        al
                                                                                                                          g


                           m
                                                                                                                                                                                          veins




In
                                                                                                                                ht



   fe                         ic
                                                                                                                                                                                                             sinus




      rio                        ve
                                                                                                                                        Ca




                                     in
                                                                                                                                                                                    Inferior cerebral




           ro
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              ph
                                                                                                                                             rn
                                                                                                                                                                                                        Superior petrosal




                   th
                      al
                                                                                                                                                ou




                         m
                                                                                                                                                   s




                            ic
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        Ce                      ve
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             nt
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          th ral v
             e
               re ein
                    tin o
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                                                                      Le
                                                                        f




                                                                                                                                                                                 In
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                                                                                                                                                   In                               f
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                                                                                                                                                     te                                 er
                                                                                                                                                                                          ior
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                                                                                                                                                        rc
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                                                                                                                                                    sin ave                             sin pet
                                                                                           ou




                                                                                                                                                        us rn                               us r os
                                                                                                                                                           es ou                                   a             l
                                                                                                                                                                 s
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                                                                                              inu
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                                                                                                                                                           In
                                                                                                                                                              f   er
                                                                                                                                                                    ior
                                                                                                                                                                  sin pet
                                                                                                                                                                      us r os
                                                                                                                                                                             a                   l
                                                                                                                          veins




                             Sphenoparietal sinus




                                                                                                                                                                               Su
                                                                                                                                                                                 pe
                                                                                                                    Inferior cerebral




                                                                                                                                                                                    rio
                                                                        Cerebral vein




                                                                                                                                                                                  si r p
                                                                                                                                                                                    nu et
                                                                      Superficial middle




                                                                                                                                                                                       s ros
                                                                                                                                                                                            al
Inferior
Tributaries of Cavernous Sinus
s
                             i nu
                         S
                     s
                 n ou
             r
          ve
        Ca
   ht
Rig                                                         us
                                                        S in
                                                    s
                                                  ou
                                            e   rn
                                          av
                                        tC
                                     Lef



                                                                               Foramen Vesalius

                                                                       Foramen Ovale
                                                                 Foramen Lacerum




                                 Pharyngeal                                  Pterygoid
                                   Plexus                                     Plexus
8- Inferior Petrosal Sinus




                                                           s
                                                       i nu
                                                   S
                                               s
                                           n ou
                                       r
                                    ve
                                  Ca
                             ht
                          Rig                                                         us
                                                                                  S in
                                                                              s
                                                                            ou
                                                                      e   rn
                                                                    av
                                                                  tC
                                                               Lef



                                                                                                   Foramen Vesalius

                                                                                            Foramen Ovale
 1- Superior Ophthalmic Vein                                                           Foramen Lacerum
2- Inferior Ophthalmic Vein

3- Sphenoparietal sinus

4- Anterior Facial Vein                                    Pharyngeal                              Pterygoid
                                                             Plexus                                 Plexus
Dangerous area of the Face
-The flow of blood in all the tributaries and communications of the
   cavernous sinus is reversible because they possess no valves.
-Spread of infection to the cavernous sinus leads to its thrombosis.
-The cavernous sinus communicates with the veins draining the
   middle area of the face (dangerous area of the face) through 2
   routes:
1-Superior ophthalmic vein.
2-Deep facial vein, pterygoid plexus of veins and emissary vein
   through the foramen ovale.
Cavernous Sinus Thrombosis
If the cavernous sinus is thrombosed what are the important structures that
                             may be affected??
                 Q. What is the clinical picture of CST ?

•   A. Clinical features of CST
•   General features of infection: fever, rigors, malaise, and sever frontal and orbital headache.
•   Unilateral exophthalmos and tender eye ball
•   Oedema of the eyelid and chemosis of the conjunctiva (due to obstruction of the superior and inferior ophthalmic veins).
•    Third, fourth, sixth cranial nerves and ophthalmic and maxillary divisions of the fifth cranial nerve may be affected
    (paralysis or paresis):
•   * Clinical picture of oculomotor paralysis:
     –     External ophthalmoplegia: Paralysis of movements of the affected eye (upward, downward and medial). Ptosis: due
          to paralysis of the levator palpebrae superioris. Slight exophthalmos.
     –     Internal ophthalmoplegia: Dilated fixed pupil with loss of accommodation reflex. (due to paralysis of the sphincter
          papillae and cilliary muscles).
•    *Paralysis of abducent nerve: Paralysis of outward movement of the affected eye.( due to paralysis of lateral rectus
    muscle)
•    * Paralysis of trochlear nerve: Paralysis of outward and downward movement of the affected eye. (due to paralysis of
    superior oblique muscle)
•   * Anesthesia in the distribution of ophthalmic division of the trigeminal nerve, decreased or absent corneal reflex and
    possibly anesthesia in the maxillary branch distribution.
•   5 . Infection can spread to the contralateral cavernous sinus within 24–48 hr of initial presentation. The earliest feature of
    such spread is affection of the abducent nerve (6 th cranial nerve) on the opposite side (paralysis of outward movement of the
    affected eye).
Thanks

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Cavernous sinus anatomy

  • 1. Cavernous Sinus By Dr. Noura El Tahawy
  • 2. Position & Extension -on the side of the body of sphenoid, -extending from the apex of the petrous temporal bone (behind) to the medial end of the superior orbital fissure (in front). -Each sinus is 2 cm long and 1 cm wide,
  • 3.
  • 4.
  • 6. * Medially: • Sphenoidal air sinus. • Hypophysis cerebri. * Laterally: • Trigeminal ganglion. • Uncus of the temporal lobe. * Nerves in its lateral wall: (from above downwards) • Oculomotor nerve. • Trochlear nerve. • Ophthalmic division of trigeminal nerve. • Maxillary division of trigeminal nerve. * Structures within its cavity. • Internal carotid artery. • Abducent nerve (on the lateral side of the artery). • -carotid sympathetic plexus • N.B.: The internal carotid artery may rupture inside the cavernous sinus due to fracture base of the skull. This results in a pulsating swelling behind the orbit.
  • 7. Coronal section of the cavernous sinus.
  • 9.
  • 10. Cavernous Sinuses Optic Chiasma Internal Carotid Artery Uncus of Pituitary Sphenoidal Temporal Lobe Gland Air Sinus Sphenoidal AirSinuses Body of Sphenoid Bone
  • 11. Medial end of The superior orbital fissure Uncus Optic Chaisma Temporal lobe Apex of petrous Trigeminal Ganglion
  • 12. Content of the Cavernous Sinuses Occulomotor Nerve Trochlear Nerve Ophthalmic Nerve Maxillary Nerve Internal carotid Artery Abducent Nerve with Sympathetic Plexus
  • 14. Anteriorly: • Ophthalmic veins (connect it with the facial vein in the face). • Sphenoparietal sinus. Posteriorly: • Superior petrosal sinus (connects it with the transverse sinus). • Inferior petrosal sinus (connects it with the internal jugular vein). Medially: • Anterior and posterior intercavernous sinuses (connect the 2cavernous sinuses together). Superiorly: • Superficial middle cerebral vein (from the lateral surface of the • brain). • Cerebral veins from the inferior surface of the brain. Inferiorly: • Emissary vein through the carotid canal (connects it with the internal jugular vein). • Emissary vein through the foramen ovale (connects it with the pterygoid plexus of veins).
  • 15. Superior and inferior Ophthalmic veins Plexus of emissary veins through carotid canal to internal jugular vein inferior Petrosal sinus
  • 16.
  • 17. Tributaries of Cavernous Sinus Anteriorly, Posteriorly, Medially and Superiorly
  • 18. In fe Ce rio Cerebral vein nt ro th ral Superficial middle Su pe ph e ve th re in Sphenoparietal sinus r io al tin o ro m a f ph ic th ve al in m Su ic pe ve r io in ro ph th Ri al g m veins In ht fe ic sinus rio ve Ca in Inferior cerebral ro ve ph rn Superior petrosal th al ou m s ic S Ce ve in inu nt s th ral v e re ein tin o a f Le f In tC In f a te er ior ve rc rn sin ave sin pet ou us rn us r os es ou a l s sS inu s In f er ior sin pet us r os a l veins Sphenoparietal sinus Su pe Inferior cerebral rio Cerebral vein si r p nu et Superficial middle s ros al
  • 20. s i nu S s n ou r ve Ca ht Rig us S in s ou e rn av tC Lef Foramen Vesalius Foramen Ovale Foramen Lacerum Pharyngeal Pterygoid Plexus Plexus
  • 21. 8- Inferior Petrosal Sinus s i nu S s n ou r ve Ca ht Rig us S in s ou e rn av tC Lef Foramen Vesalius Foramen Ovale 1- Superior Ophthalmic Vein Foramen Lacerum 2- Inferior Ophthalmic Vein 3- Sphenoparietal sinus 4- Anterior Facial Vein Pharyngeal Pterygoid Plexus Plexus
  • 22.
  • 23. Dangerous area of the Face
  • 24. -The flow of blood in all the tributaries and communications of the cavernous sinus is reversible because they possess no valves. -Spread of infection to the cavernous sinus leads to its thrombosis. -The cavernous sinus communicates with the veins draining the middle area of the face (dangerous area of the face) through 2 routes: 1-Superior ophthalmic vein. 2-Deep facial vein, pterygoid plexus of veins and emissary vein through the foramen ovale.
  • 26. If the cavernous sinus is thrombosed what are the important structures that may be affected?? Q. What is the clinical picture of CST ? • A. Clinical features of CST • General features of infection: fever, rigors, malaise, and sever frontal and orbital headache. • Unilateral exophthalmos and tender eye ball • Oedema of the eyelid and chemosis of the conjunctiva (due to obstruction of the superior and inferior ophthalmic veins). • Third, fourth, sixth cranial nerves and ophthalmic and maxillary divisions of the fifth cranial nerve may be affected (paralysis or paresis): • * Clinical picture of oculomotor paralysis: – External ophthalmoplegia: Paralysis of movements of the affected eye (upward, downward and medial). Ptosis: due to paralysis of the levator palpebrae superioris. Slight exophthalmos. – Internal ophthalmoplegia: Dilated fixed pupil with loss of accommodation reflex. (due to paralysis of the sphincter papillae and cilliary muscles). • *Paralysis of abducent nerve: Paralysis of outward movement of the affected eye.( due to paralysis of lateral rectus muscle) • * Paralysis of trochlear nerve: Paralysis of outward and downward movement of the affected eye. (due to paralysis of superior oblique muscle) • * Anesthesia in the distribution of ophthalmic division of the trigeminal nerve, decreased or absent corneal reflex and possibly anesthesia in the maxillary branch distribution. • 5 . Infection can spread to the contralateral cavernous sinus within 24–48 hr of initial presentation. The earliest feature of such spread is affection of the abducent nerve (6 th cranial nerve) on the opposite side (paralysis of outward movement of the affected eye).