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Moderator- Dr.Sameer Dikshit
Dr.Sameer Dikshit MD, DGO,FCPS,FICOG Fetal Medicine Consultant ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Dr.Poonam Loomba
Dr.Ratna Kaul
Dr.Chander Lulla
Dr.Sabuj Sengupta
Dr.Madhuri Sengupta
[object Object],[object Object],[object Object],Case #1
[object Object],[object Object]
How will you proceed?
USG done showed:-
28 weeks GA Measurement Weeks BPD 64 mm 26 weeks HC 234 mm 25 week 4 days AC 201 mm 24 weeks 5 days FL 44 mm 24 weeks 3 days
Is this information sufficient?
28 weeks GA Measurement Weeks Centile BPD 64 mm 26 weeks <2 nd HC 234 mm 25 week 4 days <2 nd AC 201 mm 24 weeks 5 days <2 nd FL 44 mm 24 weeks 3 days <2 nd
Would you call this IUGR?
28 weeks GA Measurement Weeks Centile BPD 64 mm 26 weeks <2 nd HC 234 mm 25 week 4 days <2 nd AC 201 mm 24 weeks 5 days <2 nd FL 44 mm 24 weeks 3 days <2 nd Weight 735 gms 10 th
Now, would you call this IUGR? What is more significant? AC or EFW?
 
Umbilical Vein (LUV) Intra hepatic portion of UV Portal  Sinus Right Portal vein Ductus Venosus IVC Left Portal vein Left Hepatic vein Right  Hepatic vein Superior mesenteric vein & splenic vein Left Liver Lobe Right Liver Lobe
Evolution of IUGR ,[object Object],[object Object]
[object Object],[object Object],Pre Clinical Phase
[object Object],[object Object],[object Object],[object Object],[object Object],Clinical Phase
Let us assume that both AC and EFW are less
28 weeks GA Measurement Weeks Centile BPD 64 mm 26 weeks <2 nd HC 234 mm 25 week 4 days <2 nd AC 201 mm 24 weeks 5 days <2 nd FL 44 mm 24 weeks 3 days <2 nd Weight 535 gms <2 nd
Any other sonography finding you would like to know?
28 weeks GA Measurement Weeks Centile BPD 64 mm 26 weeks <2 nd HC 234 mm 25 week 4 days <2 nd AC 201 mm 24 weeks 5 days <2 nd FL 44 mm 24 weeks 3 days <2 nd Weight 735 gms 10 th   AFI 15 cm
What investigations would you like to do?
Could this be due to Perinatal Infection? ,[object Object]
Ventriculomegaly ,[object Object]
Intra Cranial Calcifications ,[object Object]
Hepatic Calcifications ,[object Object]
Thick Placenta ,[object Object]
Fetal Hydrops ,[object Object]
Echogenic Bowel ,[object Object]
Could this be a genetic syndrome?
[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
What about Doppler Studies?
What vessels will you study?
[object Object],[object Object]
What are cut-off values?
http://www.perinatology.com/calculators/umbilicalartery.htm
http://www.perinatology.com/calculators/exbiometry.htm
At 30 weeks.. 5 th  centile 95 th  centile Umb Artery PI 1.1 0.88 1.39 MCA  PI 2.1 1.51 3.0 CPR 1.9
What is the interpretation? When will you repeat the test?
At 32 weeks.. 5 th  centile 95 th  centile Umb Artery PI 1.4 0.7 1.23 MCA  PI 1.8 1.5 2.8 CPR 1.28
What is the interpretation? How often will you monitor the pregnancy now?
At 33 weeks.. 5 th  centile 95 th  centile Umb Artery PI 1.7 0.6 1.21 MCA  PI 1.2 1.4 2.7 CPR 0.7
Ductus Venosus doppler shows “A wave reversal. What will you do now?
Is there some test before DV abnormalities?
Reversal of flow in Aortic Isthmus
[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
 
Doppler Parameter Days to delivery/ demise Abn Umb A PI 3 weeks Abn CPR 2 weeks Absent Umb A EDV 10 days Abn MCA PI 7 days Reversed Umb A EDV 5 days Elevated DV PI 3 days Umb V Pulsation 2 days Reversed DV a Wave 1 day
Mild Disease ,[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object]
Progressive Disease ,[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
Severe Early Onset ,[object Object],[object Object],[object Object]
[object Object],[object Object]
 
Role of NST….?
If NST is non reactive at 37 weeks, which Doppler study would you recommend?
Doppler changes in IUGR ,[object Object],[object Object],[object Object]
[object Object],Stage of Normoxemic Centralisation
Stage of Hypoxemic Centralisation  ,[object Object],[object Object],[object Object],[object Object],[object Object]
Stage of Decompensation ,[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
[object Object]
Is there any role of Fetal Biophysical Profile?
Uterine Artery Doppler showed bilateral diastolic notches. What is the significance?
How will you manage the pregnancy during labour?
Role of Fetal ST wave analysis?
STAN S-31
 
[object Object],[object Object],STAN- ST waveform Analysis
[object Object],[object Object],[object Object],Limitations
[object Object],[object Object],[object Object],False Negatives
What about Fetal Pulse Oximeters?
[object Object],[object Object],[object Object],[object Object],Fetal Pulse Oximeter
[object Object],[object Object],[object Object],[object Object]
Where does continuous electronic Fetal Monitoring stack??
[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],Confidential Inquiries into Stillbirth
[object Object],[object Object],[object Object],[object Object],ACOG Recommendations
[object Object],[object Object],[object Object]
[object Object],[object Object],Case#2
Which is the better route for cervical length assessment? PA or PV??
[object Object],[object Object],[object Object]
What is the technique for measuring cervical length?
[object Object],[object Object],[object Object],[object Object]
[object Object]
What is the significance of cervical length?
[object Object],[object Object],[object Object]
 
What is the significance of past h/o Preterm Delivery in the obstetric outcome
[object Object],[object Object],[object Object]
Is there a role for routine screening for bacterial vaginosis?
[object Object],[object Object]
[object Object],[object Object],[object Object]
Would you offer the patient elective cerclage?
[object Object],ACOG Practice Guidelines
This patient had a cervical length of 2.8 at 14 weeks. At 23 weeks, the cervical length is 1.4 cm. What would you do? ,[object Object],[object Object]
[object Object]
[object Object],[object Object]
Before cerclage
Immediately after cerclage
4 weeks post cerclage
[object Object]
[object Object],[object Object]
What is the role of “early” cervical assessment @ 11-13 weeks? ,[object Object]
[object Object],[object Object]
 
[object Object],[object Object],[object Object],[object Object],Correct technique
 
[object Object]
What is the role of Fetal Fibronectin?
[object Object],[object Object],[object Object],Fetal Fibronectin
[object Object],[object Object],[object Object],Other tests
Amniotic Fluid Sludge
Amniotic Fluid Sludge ,[object Object]
[object Object],[object Object]
Images of Cervix
Dilatation of cervix
Funneling of cervix
Herniation of membranes
What is the significance of funneling?
[object Object],[object Object],[object Object]
[object Object],[object Object]
 
[object Object],Case #3
Is this report adequate?
[object Object],[object Object],[object Object]
It is monochorionic Twin Pregnancy How will you monitor the pregnancy?
She comes for First Trimester Screening   What is more significant? NT or Biochemistry or Both?
What is the false positive of NT measurement in Monochorionic Twins Pregnancy?
Can one predict development of TTS?
[object Object],[object Object],[object Object]
No development of TTTS
TTTS developed later
[object Object],[object Object],[object Object]
[object Object]
How frequently should one monitor the pregnancy? And what should one monitor?
[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
What are the signs of TTTS?
[object Object],[object Object],[object Object]
The pregnancy progresses to 26 weeks, there is no TTS, how will you monitor the pregnancy?
Role of cervical screening
[object Object],[object Object],[object Object]
[object Object]
[object Object],[object Object],[object Object],[object Object],Case #4
What counseling will you offer?
What other tests will you do?
What is the role of TORCH test?
Toxo IgG negative, IgM negative   ?
Toxo IgG positive, Toxo IgM positive 
Toxo IgG negative, Toxo IgM positive 
 
What are the sonological markers of TORCH infection?
 
When do these markers appear??
What is Toxo Avidity Test? How do you interpret it?
[object Object],[object Object],[object Object],Toxo Avidity Test
What test will you perform next?
[object Object],[object Object],[object Object],[object Object],[object Object],Amniotic fluid PCR
GA @ sero -conversion Risk of congenital infection Development of severe clinical signs Avidity Test Amniotic fluid PCR 1 st  Trimester 6% 61% High If negative, then fetal infection is ruled out 2 nd  Trimester 40% 25% 3 rd  Trimester 72% 9%
 
How will you treat the patient?
[object Object],[object Object],[object Object],Case#5
How will you monitor the fetus?
What things will you look for in Ultrasound examination?
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
What are sonological signs of poor glycemic control?
[object Object],[object Object],[object Object],[object Object]
How will you monitor the fetal well being?
What is the role of Doppler?
[object Object],[object Object],[object Object],Role of Doppler-
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object]
Can you predict shoulder dystocia?
[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],Case#6
When would you carry out investigations?
What investigations would you carry out?
Role of NST?
Role of Fetal BPP?
Role of Doppler?
[object Object],[object Object],Case #7 First Trimester Screening
What advise will you give”
Is the risk higher? By what percent?
Will you go for straight invasive testing?
[object Object],[object Object]
CVS or Amnio?
FISH of full Karyotype?
What about cell free DNA?
Karyotype is Normal….what next?

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Fetal monitoring panel discussion

Notes de l'éditeur

  1. IUGR
  2. TORCH? Perinatal Infection? Genetic Syndrome?
  3. PT
  4. Twins
  5. Fetal Infection
  6. Diabetes
  7. Postdated