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Management of Women with Abnormal Pap Test
Bethesda System 2001 ,[object Object],[object Object],[object Object],[object Object]
Bethesda System 2001 ,[object Object],[object Object],[object Object],[object Object],[object Object]
Comparison of Terminology  Bethesda System CIN system Dysplasia ASCUS Cellular Atypia Unspecified Cellular  changes LSIL CIN I Mild Dysplasia HSIL CIN II Moderate dysplasia CIN III Severe Dysplasia/ CIS
Management strategy depends  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Abnormal Pap test ASCUS LSIL HSIL HPV –ve HPV +ve Rpt Pap Negative Colposcopy LEEP ECC +ve -ve Treat & Follow up Diagnostic cone Treat & Follow up
ATYPICAL SQUAMOUS CELLS
ATYPICAL SQUAMOUS CELLS ,[object Object],[object Object],[object Object],[object Object],[object Object]
ASC-US ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Recommended Management of Women with ASC-US ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Rpt Cytology @ 6 & 12 Months  HPV –ve HPV +ve Rpt Cytology @ 12 months Colposcopy  ECC if no lesions or unsatisfactory colpo  No CIN CIN Repeat Cytology  @ 6, 12 months  Or  HPV DNA test @12 months Treat & follow up ASCUS
Recommended Management  of ASC-US ,[object Object],[object Object],[object Object]
Recommended Management of Women with ASC-H  (CANNOT EXCLUDE HSIL) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
ASC-H Colposcopy ECC if no lesions  or unsatisfactory colpo CIN 2,3 > ASC or HPV+ Treat & Follow up Rpt Cytology @ 6, 12 months   OR HPV DNA Test @ 12 mths No CIN 2,3  Colposcopy Negative  Routine screening
Low Grade SIL
LSIL  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
LSIL  ,[object Object],[object Object],[object Object],[object Object],[object Object]
LSIL Colposcopy Negative Unsatisfactory colpo No lesion Satisfactory Colpo Lesion in TZ ECC No CIN CIN 2,3 Cytology @ 6, 12 mths OR HPV testing Treat & Follow up
LSIL – Post Colposcopy Management ,[object Object]
HIGH GRADE SIL HSIL
High-grade Squamous Intraepithelial Lesion (HSIL) ,[object Object],[object Object],[object Object],[object Object]
HSIL Colposcopy ECC Unsatisfactory colpo Satisfactory Colpo No CIN 2,3 Diagnostic  Excisional procedure Observe with  Cytology / Colposcopy  Treat & Follow up LEEP CIN 2,3
Managing Women with HSIL UNACCEPTABLE STRATEGIES ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
SIL in Pregnancy ,[object Object],[object Object],[object Object],[object Object],[object Object]
SIL in Pregnancy ,[object Object],[object Object],[object Object],[object Object]
ASCUS & LSIL in ADOLESCENTS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
LSIL in POSTMENOPAUSAL WOMEN ,[object Object],[object Object],[object Object],[object Object]
ATYPICAL Glandular Cells
ATYPICAL GLANDULAR CELLS  ,[object Object],[object Object],[object Object]
ATYPICAL GLANDULAR CELLS  ,[object Object],[object Object],[object Object],[object Object]
ATYPICAL GLANDULAR CELLS  ,[object Object],[object Object],[object Object],[object Object],[object Object]
AIS Hysterectomy preferred Margins involved ECC +ve Reexcision  recommended Long term  Follow up Diagnostic excisional procedure If future fertility desired Conservative Management Margins negative
Management of CIN ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
TOP 10 KEY POINTS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

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Abnormal Pap Test

  • 1. Management of Women with Abnormal Pap Test
  • 2.
  • 3.
  • 4. Comparison of Terminology Bethesda System CIN system Dysplasia ASCUS Cellular Atypia Unspecified Cellular changes LSIL CIN I Mild Dysplasia HSIL CIN II Moderate dysplasia CIN III Severe Dysplasia/ CIS
  • 5.
  • 6. Abnormal Pap test ASCUS LSIL HSIL HPV –ve HPV +ve Rpt Pap Negative Colposcopy LEEP ECC +ve -ve Treat & Follow up Diagnostic cone Treat & Follow up
  • 8.
  • 9.
  • 10.
  • 11. Rpt Cytology @ 6 & 12 Months HPV –ve HPV +ve Rpt Cytology @ 12 months Colposcopy ECC if no lesions or unsatisfactory colpo No CIN CIN Repeat Cytology @ 6, 12 months Or HPV DNA test @12 months Treat & follow up ASCUS
  • 12.
  • 13.
  • 14. ASC-H Colposcopy ECC if no lesions or unsatisfactory colpo CIN 2,3 > ASC or HPV+ Treat & Follow up Rpt Cytology @ 6, 12 months OR HPV DNA Test @ 12 mths No CIN 2,3 Colposcopy Negative Routine screening
  • 16.
  • 17.
  • 18. LSIL Colposcopy Negative Unsatisfactory colpo No lesion Satisfactory Colpo Lesion in TZ ECC No CIN CIN 2,3 Cytology @ 6, 12 mths OR HPV testing Treat & Follow up
  • 19.
  • 21.
  • 22. HSIL Colposcopy ECC Unsatisfactory colpo Satisfactory Colpo No CIN 2,3 Diagnostic Excisional procedure Observe with Cytology / Colposcopy Treat & Follow up LEEP CIN 2,3
  • 23.
  • 24.
  • 25.
  • 26.
  • 27.
  • 29.
  • 30.
  • 31.
  • 32. AIS Hysterectomy preferred Margins involved ECC +ve Reexcision recommended Long term Follow up Diagnostic excisional procedure If future fertility desired Conservative Management Margins negative
  • 33.
  • 34.