1. RADIOTHERAPY IN EARLY BREAST CANCER Dr. T. Sujit A M O ( Radiation Oncology ) Valavadi Narayanaswami Cancer Centre, G.Kuppuswamy Naidu MemorialHospital, Coimbatore - 641037, Tamilnadu, India March 2007
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13. PROCESS PRE-OP ASSESSMENT – CT / MRI / USG DETERMINATION OF TUMOR THICKNESS & BEAM ENERGY GROSS DISEASE REMOVAL, TEMP. CLOSURE OF INCISION & TRANSPORT TO RT DEPT. RE-OPENING OF INCISION, APPLICATOR PLACEMENT & TREATMENT FINAL CLOSURE OF WOUND IN OT
14. IORT - BREAST DOSE : 10 – 20 Gy IN A SINGLE FRACTION TOTAL PROCEDURE: 30 – 45 min TREATMENT TIME : 2 – 4 min EBRT ( IF REQUIRED ) – AFTER 4-6 WEEKS Single 21 Gy fraction is equivalent to 60 Gy / 30 # ( Veronesi et al )
21. IOERT Vs HDR IORT 45 – 120 min Total procedure time: 30-45 min TREATMENT RESULTS ARE EQUAL WITH REGARD TO LOCAL CONTROL, SURVIVAL AND COSMESIS. Portable, but requires shielding Logistical problems Custom made applicators for different anatomic locations Standard applicators for all patients Can be use in inaccessible sites Difficult to use in certain anatomic locations Not suitable Large tumor beds can be treated Lower dose at depth Higher dose at depth ( 2 cm ) 5 – 30 min Faster treatment time : 2-4 min > 100 % variation Better dose homogeneity: < 10% variation from surface to depth HDR IORT IOERT