SlideShare une entreprise Scribd logo
1  sur  28
RADIOTHERAPY IN EARLY BREAST CANCER Dr. T. Sujit A M O ( Radiation Oncology ) Valavadi Narayanaswami Cancer Centre, G.Kuppuswamy Naidu MemorialHospital, Coimbatore  - 641037,  Tamilnadu, India  March 2007
BCT Vs Mastectomy Trials ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
RT IN DCIS ,[object Object],[object Object],[object Object],[object Object]
RT IN EARLY INVASIVE BREAST CANCER – B C T ,[object Object],[object Object],[object Object]
WHOLE BREAST RT ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
WHOLE BREAST RT ,[object Object],[object Object],[object Object]
RT BOOST TO TUMOR BED ,[object Object],[object Object],[object Object],[object Object],Lyons Breast Cancer trial , EORTC ( Bartelink et al )
ACCELERATED PARTIAL BREAST IRRADIATION ,[object Object]
RATIONALE OF APBI ,[object Object],[object Object],[object Object]
METHODS OF DELIVERING RT ,[object Object],[object Object],[object Object],[object Object]
IOERT ,[object Object],[object Object],[object Object]
IOERT - EQUIPMENTS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
PROCESS PRE-OP ASSESSMENT – CT / MRI / USG DETERMINATION OF TUMOR THICKNESS & BEAM ENERGY GROSS DISEASE REMOVAL, TEMP. CLOSURE OF INCISION & TRANSPORT TO RT DEPT. RE-OPENING OF INCISION, APPLICATOR PLACEMENT & TREATMENT FINAL CLOSURE OF WOUND IN OT
IORT - BREAST DOSE : 10 – 20 Gy IN A SINGLE FRACTION TOTAL PROCEDURE: 30 – 45 min TREATMENT TIME : 2 – 4 min  EBRT ( IF REQUIRED ) – AFTER 4-6 WEEKS Single 21 Gy fraction is equivalent to 60 Gy / 30 # ( Veronesi et al )
HDR BT ,[object Object],[object Object],[object Object],[object Object]
 
HDR BT IN APBI ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
HDR BT AS BOOST ,[object Object],[object Object],[object Object],[object Object]
MAMMOSITE ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
MAMMOSITE DEMO
IOERT Vs HDR IORT 45 – 120 min Total procedure time: 30-45 min TREATMENT RESULTS ARE EQUAL WITH REGARD  TO LOCAL CONTROL, SURVIVAL AND COSMESIS. Portable, but requires shielding Logistical problems Custom made applicators for different anatomic locations  Standard applicators for all patients Can be use in inaccessible sites Difficult to use in certain anatomic locations Not suitable Large tumor beds can be treated Lower dose at depth Higher dose at depth ( 2 cm ) 5 – 30 min Faster treatment time : 2-4 min > 100 % variation Better dose homogeneity:  < 10% variation from surface to depth HDR IORT IOERT
Is APBI a standard treatment? ,[object Object],[object Object],[object Object],[object Object],[object Object]
RT TO THE AXILLA ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
I M N  ? ,[object Object],[object Object],[object Object]
3D CRT & IMRT ,[object Object],[object Object],[object Object],[object Object]
FACTORS INFLUENCING COSMESIS ,[object Object],[object Object],[object Object]
SEQUELAE OF THERAPY ,[object Object]
Thank  you

Contenu connexe

Tendances

TARGET DELINEATION OF CANCER ESOPHAGUS
TARGET DELINEATION OF CANCER ESOPHAGUSTARGET DELINEATION OF CANCER ESOPHAGUS
TARGET DELINEATION OF CANCER ESOPHAGUSKanhu Charan
 
Principles of radiotherapy in gastric carcinoma
Principles of radiotherapy in gastric carcinomaPrinciples of radiotherapy in gastric carcinoma
Principles of radiotherapy in gastric carcinomaAnil Gupta
 
Head and neck reirradiation
Head and neck reirradiationHead and neck reirradiation
Head and neck reirradiationKanhu Charan
 
Ca Nasopharynx contouring.pptx
Ca Nasopharynx contouring.pptxCa Nasopharynx contouring.pptx
Ca Nasopharynx contouring.pptxSayan Das
 
Hippocampal sparing whole brain radiation therapy- Making a case!
Hippocampal sparing  whole brain radiation therapy- Making a case!Hippocampal sparing  whole brain radiation therapy- Making a case!
Hippocampal sparing whole brain radiation therapy- Making a case!VIMOJ JANARDANAN NAIR
 
IMRT: Intensity Modulated Radiotherapy
IMRT: Intensity Modulated RadiotherapyIMRT: Intensity Modulated Radiotherapy
IMRT: Intensity Modulated RadiotherapyShatha M
 
Evolution of Fractionation and Conventional Fractionation in Radiotherapy
Evolution of Fractionation and Conventional Fractionation in RadiotherapyEvolution of Fractionation and Conventional Fractionation in Radiotherapy
Evolution of Fractionation and Conventional Fractionation in RadiotherapyNikhil Sebastian
 
RADIOTHERAPY IN CARCINOMA BREAST (EARLY AND LOCALLY ADVANCED)
RADIOTHERAPY IN CARCINOMA BREAST (EARLY AND LOCALLY ADVANCED)RADIOTHERAPY IN CARCINOMA BREAST (EARLY AND LOCALLY ADVANCED)
RADIOTHERAPY IN CARCINOMA BREAST (EARLY AND LOCALLY ADVANCED)DrAnkitaPatel
 
radiation therapy in ca breast
radiation therapy in ca breast   radiation therapy in ca breast
radiation therapy in ca breast Isha Jaiswal
 
Prophylactic cranial irradiation
Prophylactic cranial irradiationProphylactic cranial irradiation
Prophylactic cranial irradiationShreya Singh
 
EBRT IN CARCINOMA CERVIX
EBRT IN CARCINOMA CERVIXEBRT IN CARCINOMA CERVIX
EBRT IN CARCINOMA CERVIXIsha Jaiswal
 
BOOK ON REIRRADIATION
BOOK ON REIRRADIATIONBOOK ON REIRRADIATION
BOOK ON REIRRADIATIONKanhu Charan
 
Radiotherapy in carcinoma breast
Radiotherapy in carcinoma breastRadiotherapy in carcinoma breast
Radiotherapy in carcinoma breastSailendra Parida
 
Volumetric Modulated Arc Therapy
Volumetric Modulated Arc TherapyVolumetric Modulated Arc Therapy
Volumetric Modulated Arc Therapyfondas vakalis
 
Role of SBRT in lung cancer
Role of SBRT in lung cancerRole of SBRT in lung cancer
Role of SBRT in lung cancerDrAyush Garg
 

Tendances (20)

Rt techniques in lymphoma
Rt techniques in lymphomaRt techniques in lymphoma
Rt techniques in lymphoma
 
Breast Cancer Radiation Therapy: RT Plan evaluation & Recent Advances - 4DCT ...
Breast Cancer Radiation Therapy: RT Plan evaluation & Recent Advances - 4DCT ...Breast Cancer Radiation Therapy: RT Plan evaluation & Recent Advances - 4DCT ...
Breast Cancer Radiation Therapy: RT Plan evaluation & Recent Advances - 4DCT ...
 
TARGET DELINEATION OF CANCER ESOPHAGUS
TARGET DELINEATION OF CANCER ESOPHAGUSTARGET DELINEATION OF CANCER ESOPHAGUS
TARGET DELINEATION OF CANCER ESOPHAGUS
 
Principles of radiotherapy in gastric carcinoma
Principles of radiotherapy in gastric carcinomaPrinciples of radiotherapy in gastric carcinoma
Principles of radiotherapy in gastric carcinoma
 
Head and neck reirradiation
Head and neck reirradiationHead and neck reirradiation
Head and neck reirradiation
 
Radiotherapy breast
Radiotherapy breastRadiotherapy breast
Radiotherapy breast
 
Ca Nasopharynx contouring.pptx
Ca Nasopharynx contouring.pptxCa Nasopharynx contouring.pptx
Ca Nasopharynx contouring.pptx
 
Hippocampal sparing whole brain radiation therapy- Making a case!
Hippocampal sparing  whole brain radiation therapy- Making a case!Hippocampal sparing  whole brain radiation therapy- Making a case!
Hippocampal sparing whole brain radiation therapy- Making a case!
 
Hypofractionation in breast cancer
Hypofractionation in breast cancerHypofractionation in breast cancer
Hypofractionation in breast cancer
 
IMRT: Intensity Modulated Radiotherapy
IMRT: Intensity Modulated RadiotherapyIMRT: Intensity Modulated Radiotherapy
IMRT: Intensity Modulated Radiotherapy
 
Evolution of Fractionation and Conventional Fractionation in Radiotherapy
Evolution of Fractionation and Conventional Fractionation in RadiotherapyEvolution of Fractionation and Conventional Fractionation in Radiotherapy
Evolution of Fractionation and Conventional Fractionation in Radiotherapy
 
Altered fractionation kiran
Altered fractionation   kiranAltered fractionation   kiran
Altered fractionation kiran
 
RADIOTHERAPY IN CARCINOMA BREAST (EARLY AND LOCALLY ADVANCED)
RADIOTHERAPY IN CARCINOMA BREAST (EARLY AND LOCALLY ADVANCED)RADIOTHERAPY IN CARCINOMA BREAST (EARLY AND LOCALLY ADVANCED)
RADIOTHERAPY IN CARCINOMA BREAST (EARLY AND LOCALLY ADVANCED)
 
radiation therapy in ca breast
radiation therapy in ca breast   radiation therapy in ca breast
radiation therapy in ca breast
 
Prophylactic cranial irradiation
Prophylactic cranial irradiationProphylactic cranial irradiation
Prophylactic cranial irradiation
 
EBRT IN CARCINOMA CERVIX
EBRT IN CARCINOMA CERVIXEBRT IN CARCINOMA CERVIX
EBRT IN CARCINOMA CERVIX
 
BOOK ON REIRRADIATION
BOOK ON REIRRADIATIONBOOK ON REIRRADIATION
BOOK ON REIRRADIATION
 
Radiotherapy in carcinoma breast
Radiotherapy in carcinoma breastRadiotherapy in carcinoma breast
Radiotherapy in carcinoma breast
 
Volumetric Modulated Arc Therapy
Volumetric Modulated Arc TherapyVolumetric Modulated Arc Therapy
Volumetric Modulated Arc Therapy
 
Role of SBRT in lung cancer
Role of SBRT in lung cancerRole of SBRT in lung cancer
Role of SBRT in lung cancer
 

En vedette

Early breast cancer treatment radiotherapy
Early breast cancer treatment radiotherapyEarly breast cancer treatment radiotherapy
Early breast cancer treatment radiotherapyYan Vargas
 
Radiotherapy in Breast Cancer: Current Issues
Radiotherapy in Breast Cancer: Current IssuesRadiotherapy in Breast Cancer: Current Issues
Radiotherapy in Breast Cancer: Current IssuesJyotirup Goswami
 
Turcon rod glyd ring t rod t type glyd ring gzt
Turcon rod glyd ring t rod t type glyd ring gztTurcon rod glyd ring t rod t type glyd ring gzt
Turcon rod glyd ring t rod t type glyd ring gztwalleseals
 
Who Benefits From Apbi March2009
Who Benefits From Apbi March2009Who Benefits From Apbi March2009
Who Benefits From Apbi March2009Spectrum Health
 
Senology Newsletter - April 10, 2013
Senology Newsletter - April 10, 2013Senology Newsletter - April 10, 2013
Senology Newsletter - April 10, 2013Senology.org
 
EBRT in breast cancer: Evolution to cutting edge
EBRT in breast cancer: Evolution to cutting edgeEBRT in breast cancer: Evolution to cutting edge
EBRT in breast cancer: Evolution to cutting edgePramod Tike
 
Marc Wigoda : Radiotherapy of the Axilla in Early Breast Cancer : When and H...
Marc Wigoda :  Radiotherapy of the Axilla in Early Breast Cancer : When and H...Marc Wigoda :  Radiotherapy of the Axilla in Early Breast Cancer : When and H...
Marc Wigoda : Radiotherapy of the Axilla in Early Breast Cancer : When and H...breastcancerupdatecongress
 
Radiation pneumonitis and ddx
Radiation pneumonitis and ddxRadiation pneumonitis and ddx
Radiation pneumonitis and ddxDr. Lin
 
BALKAN MCO 2011 - J. Zgajnar and M. Margaritoni - Surgery (SLNB, management o...
BALKAN MCO 2011 - J. Zgajnar and M. Margaritoni - Surgery (SLNB, management o...BALKAN MCO 2011 - J. Zgajnar and M. Margaritoni - Surgery (SLNB, management o...
BALKAN MCO 2011 - J. Zgajnar and M. Margaritoni - Surgery (SLNB, management o...European School of Oncology
 
Occupational radiation safety in Radiotherapy, Timothy Peace S
Occupational radiation safety in Radiotherapy, Timothy Peace SOccupational radiation safety in Radiotherapy, Timothy Peace S
Occupational radiation safety in Radiotherapy, Timothy Peace Sohscmcvellore
 
49 alveolar lung disease on computed tomography
49 alveolar lung disease on computed tomography49 alveolar lung disease on computed tomography
49 alveolar lung disease on computed tomographyDr. Muhammad Bin Zulfiqar
 
Technical issues in breast radiotherapy
Technical issues in breast radiotherapyTechnical issues in breast radiotherapy
Technical issues in breast radiotherapyBharti Devnani
 
Radiotherapy of cervical cancer
Radiotherapy of cervical cancerRadiotherapy of cervical cancer
Radiotherapy of cervical cancerRakshith AVB
 
Radiotherapy In Carcinoma Of The Breast
Radiotherapy In Carcinoma Of The BreastRadiotherapy In Carcinoma Of The Breast
Radiotherapy In Carcinoma Of The Breastfondas vakalis
 
Anatomy of Axilla
Anatomy of AxillaAnatomy of Axilla
Anatomy of AxillaYapa
 

En vedette (20)

Early breast cancer treatment radiotherapy
Early breast cancer treatment radiotherapyEarly breast cancer treatment radiotherapy
Early breast cancer treatment radiotherapy
 
Radiotherapy in Breast Cancer: Current Issues
Radiotherapy in Breast Cancer: Current IssuesRadiotherapy in Breast Cancer: Current Issues
Radiotherapy in Breast Cancer: Current Issues
 
Turcon rod glyd ring t rod t type glyd ring gzt
Turcon rod glyd ring t rod t type glyd ring gztTurcon rod glyd ring t rod t type glyd ring gzt
Turcon rod glyd ring t rod t type glyd ring gzt
 
Who Benefits From Apbi March2009
Who Benefits From Apbi March2009Who Benefits From Apbi March2009
Who Benefits From Apbi March2009
 
Senology Newsletter - April 10, 2013
Senology Newsletter - April 10, 2013Senology Newsletter - April 10, 2013
Senology Newsletter - April 10, 2013
 
EBRT in breast cancer: Evolution to cutting edge
EBRT in breast cancer: Evolution to cutting edgeEBRT in breast cancer: Evolution to cutting edge
EBRT in breast cancer: Evolution to cutting edge
 
Marc Wigoda : Radiotherapy of the Axilla in Early Breast Cancer : When and H...
Marc Wigoda :  Radiotherapy of the Axilla in Early Breast Cancer : When and H...Marc Wigoda :  Radiotherapy of the Axilla in Early Breast Cancer : When and H...
Marc Wigoda : Radiotherapy of the Axilla in Early Breast Cancer : When and H...
 
Radiation pneumonitis
Radiation pneumonitisRadiation pneumonitis
Radiation pneumonitis
 
Radiation pneumonitis and ddx
Radiation pneumonitis and ddxRadiation pneumonitis and ddx
Radiation pneumonitis and ddx
 
BALKAN MCO 2011 - J. Zgajnar and M. Margaritoni - Surgery (SLNB, management o...
BALKAN MCO 2011 - J. Zgajnar and M. Margaritoni - Surgery (SLNB, management o...BALKAN MCO 2011 - J. Zgajnar and M. Margaritoni - Surgery (SLNB, management o...
BALKAN MCO 2011 - J. Zgajnar and M. Margaritoni - Surgery (SLNB, management o...
 
New Targets & New Drugs in Hepatocellular carcinoma
New Targets & New Drugs in Hepatocellular carcinomaNew Targets & New Drugs in Hepatocellular carcinoma
New Targets & New Drugs in Hepatocellular carcinoma
 
BALKAN MCO 2011 - E. Vrdoljak - Radiotherapy
BALKAN MCO 2011 - E. Vrdoljak - RadiotherapyBALKAN MCO 2011 - E. Vrdoljak - Radiotherapy
BALKAN MCO 2011 - E. Vrdoljak - Radiotherapy
 
Intra Operative Radiotherapy
Intra Operative RadiotherapyIntra Operative Radiotherapy
Intra Operative Radiotherapy
 
Occupational radiation safety in Radiotherapy, Timothy Peace S
Occupational radiation safety in Radiotherapy, Timothy Peace SOccupational radiation safety in Radiotherapy, Timothy Peace S
Occupational radiation safety in Radiotherapy, Timothy Peace S
 
49 alveolar lung disease on computed tomography
49 alveolar lung disease on computed tomography49 alveolar lung disease on computed tomography
49 alveolar lung disease on computed tomography
 
Technical issues in breast radiotherapy
Technical issues in breast radiotherapyTechnical issues in breast radiotherapy
Technical issues in breast radiotherapy
 
Brachytherapy
BrachytherapyBrachytherapy
Brachytherapy
 
Radiotherapy of cervical cancer
Radiotherapy of cervical cancerRadiotherapy of cervical cancer
Radiotherapy of cervical cancer
 
Radiotherapy In Carcinoma Of The Breast
Radiotherapy In Carcinoma Of The BreastRadiotherapy In Carcinoma Of The Breast
Radiotherapy In Carcinoma Of The Breast
 
Anatomy of Axilla
Anatomy of AxillaAnatomy of Axilla
Anatomy of Axilla
 

Similaire à Radiotherapy In Early Breast Cancer

Role of radiation in carcinoma rectum and colon
Role of radiation in carcinoma rectum and colon Role of radiation in carcinoma rectum and colon
Role of radiation in carcinoma rectum and colon Bharti Devnani
 
Treatment of Advanced stage of Carcinoma Cervix & Ca cervix in Pregnancy.pptx
Treatment of Advanced stage of Carcinoma Cervix & Ca cervix in Pregnancy.pptxTreatment of Advanced stage of Carcinoma Cervix & Ca cervix in Pregnancy.pptx
Treatment of Advanced stage of Carcinoma Cervix & Ca cervix in Pregnancy.pptxMuthuRamanK3
 
Post op radiotherapy in oral cavity cancers
Post op radiotherapy in oral cavity cancersPost op radiotherapy in oral cavity cancers
Post op radiotherapy in oral cavity cancersDr. Prashant Surkar
 
Head Neck Interstitial Brachy.pptx
Head Neck Interstitial Brachy.pptxHead Neck Interstitial Brachy.pptx
Head Neck Interstitial Brachy.pptxSayan Das
 
Management of Cancer larynx
Management of Cancer larynxManagement of Cancer larynx
Management of Cancer larynxahmed elazony
 
Management of nasopharyngeal cancer
Management of nasopharyngeal cancerManagement of nasopharyngeal cancer
Management of nasopharyngeal cancerSailendra Parida
 
Vakalis new techniques in breast radiotherapy
Vakalis new techniques in breast radiotherapyVakalis new techniques in breast radiotherapy
Vakalis new techniques in breast radiotherapyfondas vakalis
 
Brachytherapy IGABT
Brachytherapy IGABTBrachytherapy IGABT
Brachytherapy IGABTPuneet Seth
 
Role of radiotherapy and chemotherapy in oral cavity cancer
Role of radiotherapy and chemotherapy in oral cavity cancerRole of radiotherapy and chemotherapy in oral cavity cancer
Role of radiotherapy and chemotherapy in oral cavity cancerDr.Rashmi Yadav
 
Breast HDR interstitial brachytherapy
Breast HDR interstitial brachytherapyBreast HDR interstitial brachytherapy
Breast HDR interstitial brachytherapyAli Bagheri
 
Challenges in management of oral cavity cancers
Challenges in management of oral cavity cancersChallenges in management of oral cavity cancers
Challenges in management of oral cavity cancersRajib Bhattacharjee
 
2 d vs 3d planning in pelvic malignancies
2 d vs 3d planning in pelvic malignancies2 d vs 3d planning in pelvic malignancies
2 d vs 3d planning in pelvic malignanciesAbhishek Soni
 
IMRT and 3D CRT in cervical Cancers
IMRT and 3D CRT in cervical CancersIMRT and 3D CRT in cervical Cancers
IMRT and 3D CRT in cervical CancersSantam Chakraborty
 
HDR brachytherapy for Non-Melanoma Skin cancers
HDR brachytherapy for Non-Melanoma Skin cancersHDR brachytherapy for Non-Melanoma Skin cancers
HDR brachytherapy for Non-Melanoma Skin cancersAli Bagheri
 
New techniques in breast radiotherapy
New techniques in breast radiotherapyNew techniques in breast radiotherapy
New techniques in breast radiotherapyfondas vakalis
 
Esophageal cancer-role of RT
Esophageal cancer-role of RTEsophageal cancer-role of RT
Esophageal cancer-role of RTBharti Devnani
 

Similaire à Radiotherapy In Early Breast Cancer (20)

Apbi
ApbiApbi
Apbi
 
Role of radiation in carcinoma rectum and colon
Role of radiation in carcinoma rectum and colon Role of radiation in carcinoma rectum and colon
Role of radiation in carcinoma rectum and colon
 
Treatment of Advanced stage of Carcinoma Cervix & Ca cervix in Pregnancy.pptx
Treatment of Advanced stage of Carcinoma Cervix & Ca cervix in Pregnancy.pptxTreatment of Advanced stage of Carcinoma Cervix & Ca cervix in Pregnancy.pptx
Treatment of Advanced stage of Carcinoma Cervix & Ca cervix in Pregnancy.pptx
 
Radiation therapy in gynecologic cancer 17-03-15
Radiation therapy in gynecologic cancer 17-03-15Radiation therapy in gynecologic cancer 17-03-15
Radiation therapy in gynecologic cancer 17-03-15
 
Post op radiotherapy in oral cavity cancers
Post op radiotherapy in oral cavity cancersPost op radiotherapy in oral cavity cancers
Post op radiotherapy in oral cavity cancers
 
Head Neck Interstitial Brachy.pptx
Head Neck Interstitial Brachy.pptxHead Neck Interstitial Brachy.pptx
Head Neck Interstitial Brachy.pptx
 
Management of Cancer larynx
Management of Cancer larynxManagement of Cancer larynx
Management of Cancer larynx
 
Management of nasopharyngeal cancer
Management of nasopharyngeal cancerManagement of nasopharyngeal cancer
Management of nasopharyngeal cancer
 
Vakalis new techniques in breast radiotherapy
Vakalis new techniques in breast radiotherapyVakalis new techniques in breast radiotherapy
Vakalis new techniques in breast radiotherapy
 
Brachytherapy IGABT
Brachytherapy IGABTBrachytherapy IGABT
Brachytherapy IGABT
 
Nasopharynx
Nasopharynx Nasopharynx
Nasopharynx
 
Role of radiotherapy and chemotherapy in oral cavity cancer
Role of radiotherapy and chemotherapy in oral cavity cancerRole of radiotherapy and chemotherapy in oral cavity cancer
Role of radiotherapy and chemotherapy in oral cavity cancer
 
Breast HDR interstitial brachytherapy
Breast HDR interstitial brachytherapyBreast HDR interstitial brachytherapy
Breast HDR interstitial brachytherapy
 
Challenges in management of oral cavity cancers
Challenges in management of oral cavity cancersChallenges in management of oral cavity cancers
Challenges in management of oral cavity cancers
 
2 d vs 3d planning in pelvic malignancies
2 d vs 3d planning in pelvic malignancies2 d vs 3d planning in pelvic malignancies
2 d vs 3d planning in pelvic malignancies
 
IMRT and 3D CRT in cervical Cancers
IMRT and 3D CRT in cervical CancersIMRT and 3D CRT in cervical Cancers
IMRT and 3D CRT in cervical Cancers
 
HDR brachytherapy for Non-Melanoma Skin cancers
HDR brachytherapy for Non-Melanoma Skin cancersHDR brachytherapy for Non-Melanoma Skin cancers
HDR brachytherapy for Non-Melanoma Skin cancers
 
Management of lung cancer
Management of lung cancerManagement of lung cancer
Management of lung cancer
 
New techniques in breast radiotherapy
New techniques in breast radiotherapyNew techniques in breast radiotherapy
New techniques in breast radiotherapy
 
Esophageal cancer-role of RT
Esophageal cancer-role of RTEsophageal cancer-role of RT
Esophageal cancer-role of RT
 

Plus de Dr.T.Sujit :-)

Understanding Cancer & Radiation Therapy
Understanding Cancer & Radiation TherapyUnderstanding Cancer & Radiation Therapy
Understanding Cancer & Radiation TherapyDr.T.Sujit :-)
 
Oncological emergencies - 2014
Oncological emergencies - 2014Oncological emergencies - 2014
Oncological emergencies - 2014Dr.T.Sujit :-)
 
Incidence and trends in cancer in India
Incidence and trends in cancer in IndiaIncidence and trends in cancer in India
Incidence and trends in cancer in IndiaDr.T.Sujit :-)
 
Pain management in cancer patients
Pain management in cancer patientsPain management in cancer patients
Pain management in cancer patientsDr.T.Sujit :-)
 
Cancer in Adolescents and Young Adults
Cancer in Adolescents and Young AdultsCancer in Adolescents and Young Adults
Cancer in Adolescents and Young AdultsDr.T.Sujit :-)
 
Leptomeningeal Metastases
Leptomeningeal MetastasesLeptomeningeal Metastases
Leptomeningeal MetastasesDr.T.Sujit :-)
 
Nat Aroicon 2007 Sujit 1.2
Nat Aroicon 2007 Sujit 1.2Nat Aroicon 2007 Sujit 1.2
Nat Aroicon 2007 Sujit 1.2Dr.T.Sujit :-)
 
Adjuvant Therapy In Uterine Sarcomas
Adjuvant Therapy In Uterine SarcomasAdjuvant Therapy In Uterine Sarcomas
Adjuvant Therapy In Uterine SarcomasDr.T.Sujit :-)
 

Plus de Dr.T.Sujit :-) (11)

Understanding Cancer & Radiation Therapy
Understanding Cancer & Radiation TherapyUnderstanding Cancer & Radiation Therapy
Understanding Cancer & Radiation Therapy
 
Oncological emergencies - 2014
Oncological emergencies - 2014Oncological emergencies - 2014
Oncological emergencies - 2014
 
Incidence and trends in cancer in India
Incidence and trends in cancer in IndiaIncidence and trends in cancer in India
Incidence and trends in cancer in India
 
Pain management in cancer patients
Pain management in cancer patientsPain management in cancer patients
Pain management in cancer patients
 
Cancer in Adolescents and Young Adults
Cancer in Adolescents and Young AdultsCancer in Adolescents and Young Adults
Cancer in Adolescents and Young Adults
 
Leptomeningeal mets
Leptomeningeal metsLeptomeningeal mets
Leptomeningeal mets
 
Leptomeningeal Metastases
Leptomeningeal MetastasesLeptomeningeal Metastases
Leptomeningeal Metastases
 
IMRT IN CANCER CERVIX
IMRT IN CANCER CERVIXIMRT IN CANCER CERVIX
IMRT IN CANCER CERVIX
 
Nat Aroicon 2007 Sujit 1.2
Nat Aroicon 2007 Sujit 1.2Nat Aroicon 2007 Sujit 1.2
Nat Aroicon 2007 Sujit 1.2
 
Adjuvant Therapy In Uterine Sarcomas
Adjuvant Therapy In Uterine SarcomasAdjuvant Therapy In Uterine Sarcomas
Adjuvant Therapy In Uterine Sarcomas
 
RT in Ca Esophagus
RT in Ca EsophagusRT in Ca Esophagus
RT in Ca Esophagus
 

Dernier

College Call Girls Vyasarpadi Whatsapp 7001305949 Independent Escort Service
College Call Girls Vyasarpadi Whatsapp 7001305949 Independent Escort ServiceCollege Call Girls Vyasarpadi Whatsapp 7001305949 Independent Escort Service
College Call Girls Vyasarpadi Whatsapp 7001305949 Independent Escort ServiceNehru place Escorts
 
Hematology and Immunology - Leukocytes Functions
Hematology and Immunology - Leukocytes FunctionsHematology and Immunology - Leukocytes Functions
Hematology and Immunology - Leukocytes FunctionsMedicoseAcademics
 
Housewife Call Girls Hsr Layout - Call 7001305949 Rs-3500 with A/C Room Cash ...
Housewife Call Girls Hsr Layout - Call 7001305949 Rs-3500 with A/C Room Cash ...Housewife Call Girls Hsr Layout - Call 7001305949 Rs-3500 with A/C Room Cash ...
Housewife Call Girls Hsr Layout - Call 7001305949 Rs-3500 with A/C Room Cash ...narwatsonia7
 
Call Girl Service Bidadi - For 7001305949 Cheap & Best with original Photos
Call Girl Service Bidadi - For 7001305949 Cheap & Best with original PhotosCall Girl Service Bidadi - For 7001305949 Cheap & Best with original Photos
Call Girl Service Bidadi - For 7001305949 Cheap & Best with original Photosnarwatsonia7
 
Low Rate Call Girls Mumbai Suman 9910780858 Independent Escort Service Mumbai
Low Rate Call Girls Mumbai Suman 9910780858 Independent Escort Service MumbaiLow Rate Call Girls Mumbai Suman 9910780858 Independent Escort Service Mumbai
Low Rate Call Girls Mumbai Suman 9910780858 Independent Escort Service Mumbaisonalikaur4
 
Call Girls Kanakapura Road Just Call 7001305949 Top Class Call Girl Service A...
Call Girls Kanakapura Road Just Call 7001305949 Top Class Call Girl Service A...Call Girls Kanakapura Road Just Call 7001305949 Top Class Call Girl Service A...
Call Girls Kanakapura Road Just Call 7001305949 Top Class Call Girl Service A...narwatsonia7
 
call girls in green park DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️
call girls in green park  DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️call girls in green park  DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️
call girls in green park DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️saminamagar
 
Call Girls Hosur Just Call 7001305949 Top Class Call Girl Service Available
Call Girls Hosur Just Call 7001305949 Top Class Call Girl Service AvailableCall Girls Hosur Just Call 7001305949 Top Class Call Girl Service Available
Call Girls Hosur Just Call 7001305949 Top Class Call Girl Service Availablenarwatsonia7
 
Call Girls Electronic City Just Call 7001305949 Top Class Call Girl Service A...
Call Girls Electronic City Just Call 7001305949 Top Class Call Girl Service A...Call Girls Electronic City Just Call 7001305949 Top Class Call Girl Service A...
Call Girls Electronic City Just Call 7001305949 Top Class Call Girl Service A...narwatsonia7
 
Call Girls Viman Nagar 7001305949 All Area Service COD available Any Time
Call Girls Viman Nagar 7001305949 All Area Service COD available Any TimeCall Girls Viman Nagar 7001305949 All Area Service COD available Any Time
Call Girls Viman Nagar 7001305949 All Area Service COD available Any Timevijaych2041
 
Call Girls Frazer Town Just Call 7001305949 Top Class Call Girl Service Avail...
Call Girls Frazer Town Just Call 7001305949 Top Class Call Girl Service Avail...Call Girls Frazer Town Just Call 7001305949 Top Class Call Girl Service Avail...
Call Girls Frazer Town Just Call 7001305949 Top Class Call Girl Service Avail...narwatsonia7
 
Call Girl Lucknow Mallika 7001305949 Independent Escort Service Lucknow
Call Girl Lucknow Mallika 7001305949 Independent Escort Service LucknowCall Girl Lucknow Mallika 7001305949 Independent Escort Service Lucknow
Call Girl Lucknow Mallika 7001305949 Independent Escort Service Lucknownarwatsonia7
 
VIP Call Girls Lucknow Nandini 7001305949 Independent Escort Service Lucknow
VIP Call Girls Lucknow Nandini 7001305949 Independent Escort Service LucknowVIP Call Girls Lucknow Nandini 7001305949 Independent Escort Service Lucknow
VIP Call Girls Lucknow Nandini 7001305949 Independent Escort Service Lucknownarwatsonia7
 
Book Call Girls in Kasavanahalli - 7001305949 with real photos and phone numbers
Book Call Girls in Kasavanahalli - 7001305949 with real photos and phone numbersBook Call Girls in Kasavanahalli - 7001305949 with real photos and phone numbers
Book Call Girls in Kasavanahalli - 7001305949 with real photos and phone numbersnarwatsonia7
 
Call Girl Bangalore Nandini 7001305949 Independent Escort Service Bangalore
Call Girl Bangalore Nandini 7001305949 Independent Escort Service BangaloreCall Girl Bangalore Nandini 7001305949 Independent Escort Service Bangalore
Call Girl Bangalore Nandini 7001305949 Independent Escort Service Bangalorenarwatsonia7
 
Noida Sector 135 Call Girls ( 9873940964 ) Book Hot And Sexy Girls In A Few C...
Noida Sector 135 Call Girls ( 9873940964 ) Book Hot And Sexy Girls In A Few C...Noida Sector 135 Call Girls ( 9873940964 ) Book Hot And Sexy Girls In A Few C...
Noida Sector 135 Call Girls ( 9873940964 ) Book Hot And Sexy Girls In A Few C...rajnisinghkjn
 
Pharmaceutical Marketting: Unit-5, Pricing
Pharmaceutical Marketting: Unit-5, PricingPharmaceutical Marketting: Unit-5, Pricing
Pharmaceutical Marketting: Unit-5, PricingArunagarwal328757
 
Call Girls Whitefield Just Call 7001305949 Top Class Call Girl Service Available
Call Girls Whitefield Just Call 7001305949 Top Class Call Girl Service AvailableCall Girls Whitefield Just Call 7001305949 Top Class Call Girl Service Available
Call Girls Whitefield Just Call 7001305949 Top Class Call Girl Service Availablenarwatsonia7
 
Call Girls Service Nandiambakkam | 7001305949 At Low Cost Cash Payment Booking
Call Girls Service Nandiambakkam | 7001305949 At Low Cost Cash Payment BookingCall Girls Service Nandiambakkam | 7001305949 At Low Cost Cash Payment Booking
Call Girls Service Nandiambakkam | 7001305949 At Low Cost Cash Payment BookingNehru place Escorts
 
97111 47426 Call Girls In Delhi MUNIRKAA
97111 47426 Call Girls In Delhi MUNIRKAA97111 47426 Call Girls In Delhi MUNIRKAA
97111 47426 Call Girls In Delhi MUNIRKAAjennyeacort
 

Dernier (20)

College Call Girls Vyasarpadi Whatsapp 7001305949 Independent Escort Service
College Call Girls Vyasarpadi Whatsapp 7001305949 Independent Escort ServiceCollege Call Girls Vyasarpadi Whatsapp 7001305949 Independent Escort Service
College Call Girls Vyasarpadi Whatsapp 7001305949 Independent Escort Service
 
Hematology and Immunology - Leukocytes Functions
Hematology and Immunology - Leukocytes FunctionsHematology and Immunology - Leukocytes Functions
Hematology and Immunology - Leukocytes Functions
 
Housewife Call Girls Hsr Layout - Call 7001305949 Rs-3500 with A/C Room Cash ...
Housewife Call Girls Hsr Layout - Call 7001305949 Rs-3500 with A/C Room Cash ...Housewife Call Girls Hsr Layout - Call 7001305949 Rs-3500 with A/C Room Cash ...
Housewife Call Girls Hsr Layout - Call 7001305949 Rs-3500 with A/C Room Cash ...
 
Call Girl Service Bidadi - For 7001305949 Cheap & Best with original Photos
Call Girl Service Bidadi - For 7001305949 Cheap & Best with original PhotosCall Girl Service Bidadi - For 7001305949 Cheap & Best with original Photos
Call Girl Service Bidadi - For 7001305949 Cheap & Best with original Photos
 
Low Rate Call Girls Mumbai Suman 9910780858 Independent Escort Service Mumbai
Low Rate Call Girls Mumbai Suman 9910780858 Independent Escort Service MumbaiLow Rate Call Girls Mumbai Suman 9910780858 Independent Escort Service Mumbai
Low Rate Call Girls Mumbai Suman 9910780858 Independent Escort Service Mumbai
 
Call Girls Kanakapura Road Just Call 7001305949 Top Class Call Girl Service A...
Call Girls Kanakapura Road Just Call 7001305949 Top Class Call Girl Service A...Call Girls Kanakapura Road Just Call 7001305949 Top Class Call Girl Service A...
Call Girls Kanakapura Road Just Call 7001305949 Top Class Call Girl Service A...
 
call girls in green park DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️
call girls in green park  DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️call girls in green park  DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️
call girls in green park DELHI 🔝 >༒9540349809 🔝 genuine Escort Service 🔝✔️✔️
 
Call Girls Hosur Just Call 7001305949 Top Class Call Girl Service Available
Call Girls Hosur Just Call 7001305949 Top Class Call Girl Service AvailableCall Girls Hosur Just Call 7001305949 Top Class Call Girl Service Available
Call Girls Hosur Just Call 7001305949 Top Class Call Girl Service Available
 
Call Girls Electronic City Just Call 7001305949 Top Class Call Girl Service A...
Call Girls Electronic City Just Call 7001305949 Top Class Call Girl Service A...Call Girls Electronic City Just Call 7001305949 Top Class Call Girl Service A...
Call Girls Electronic City Just Call 7001305949 Top Class Call Girl Service A...
 
Call Girls Viman Nagar 7001305949 All Area Service COD available Any Time
Call Girls Viman Nagar 7001305949 All Area Service COD available Any TimeCall Girls Viman Nagar 7001305949 All Area Service COD available Any Time
Call Girls Viman Nagar 7001305949 All Area Service COD available Any Time
 
Call Girls Frazer Town Just Call 7001305949 Top Class Call Girl Service Avail...
Call Girls Frazer Town Just Call 7001305949 Top Class Call Girl Service Avail...Call Girls Frazer Town Just Call 7001305949 Top Class Call Girl Service Avail...
Call Girls Frazer Town Just Call 7001305949 Top Class Call Girl Service Avail...
 
Call Girl Lucknow Mallika 7001305949 Independent Escort Service Lucknow
Call Girl Lucknow Mallika 7001305949 Independent Escort Service LucknowCall Girl Lucknow Mallika 7001305949 Independent Escort Service Lucknow
Call Girl Lucknow Mallika 7001305949 Independent Escort Service Lucknow
 
VIP Call Girls Lucknow Nandini 7001305949 Independent Escort Service Lucknow
VIP Call Girls Lucknow Nandini 7001305949 Independent Escort Service LucknowVIP Call Girls Lucknow Nandini 7001305949 Independent Escort Service Lucknow
VIP Call Girls Lucknow Nandini 7001305949 Independent Escort Service Lucknow
 
Book Call Girls in Kasavanahalli - 7001305949 with real photos and phone numbers
Book Call Girls in Kasavanahalli - 7001305949 with real photos and phone numbersBook Call Girls in Kasavanahalli - 7001305949 with real photos and phone numbers
Book Call Girls in Kasavanahalli - 7001305949 with real photos and phone numbers
 
Call Girl Bangalore Nandini 7001305949 Independent Escort Service Bangalore
Call Girl Bangalore Nandini 7001305949 Independent Escort Service BangaloreCall Girl Bangalore Nandini 7001305949 Independent Escort Service Bangalore
Call Girl Bangalore Nandini 7001305949 Independent Escort Service Bangalore
 
Noida Sector 135 Call Girls ( 9873940964 ) Book Hot And Sexy Girls In A Few C...
Noida Sector 135 Call Girls ( 9873940964 ) Book Hot And Sexy Girls In A Few C...Noida Sector 135 Call Girls ( 9873940964 ) Book Hot And Sexy Girls In A Few C...
Noida Sector 135 Call Girls ( 9873940964 ) Book Hot And Sexy Girls In A Few C...
 
Pharmaceutical Marketting: Unit-5, Pricing
Pharmaceutical Marketting: Unit-5, PricingPharmaceutical Marketting: Unit-5, Pricing
Pharmaceutical Marketting: Unit-5, Pricing
 
Call Girls Whitefield Just Call 7001305949 Top Class Call Girl Service Available
Call Girls Whitefield Just Call 7001305949 Top Class Call Girl Service AvailableCall Girls Whitefield Just Call 7001305949 Top Class Call Girl Service Available
Call Girls Whitefield Just Call 7001305949 Top Class Call Girl Service Available
 
Call Girls Service Nandiambakkam | 7001305949 At Low Cost Cash Payment Booking
Call Girls Service Nandiambakkam | 7001305949 At Low Cost Cash Payment BookingCall Girls Service Nandiambakkam | 7001305949 At Low Cost Cash Payment Booking
Call Girls Service Nandiambakkam | 7001305949 At Low Cost Cash Payment Booking
 
97111 47426 Call Girls In Delhi MUNIRKAA
97111 47426 Call Girls In Delhi MUNIRKAA97111 47426 Call Girls In Delhi MUNIRKAA
97111 47426 Call Girls In Delhi MUNIRKAA
 

Radiotherapy In Early Breast Cancer

  • 1. RADIOTHERAPY IN EARLY BREAST CANCER Dr. T. Sujit A M O ( Radiation Oncology ) Valavadi Narayanaswami Cancer Centre, G.Kuppuswamy Naidu MemorialHospital, Coimbatore - 641037, Tamilnadu, India March 2007
  • 2.
  • 3.
  • 4.
  • 5.
  • 6.
  • 7.
  • 8.
  • 9.
  • 10.
  • 11.
  • 12.
  • 13. PROCESS PRE-OP ASSESSMENT – CT / MRI / USG DETERMINATION OF TUMOR THICKNESS & BEAM ENERGY GROSS DISEASE REMOVAL, TEMP. CLOSURE OF INCISION & TRANSPORT TO RT DEPT. RE-OPENING OF INCISION, APPLICATOR PLACEMENT & TREATMENT FINAL CLOSURE OF WOUND IN OT
  • 14. IORT - BREAST DOSE : 10 – 20 Gy IN A SINGLE FRACTION TOTAL PROCEDURE: 30 – 45 min TREATMENT TIME : 2 – 4 min EBRT ( IF REQUIRED ) – AFTER 4-6 WEEKS Single 21 Gy fraction is equivalent to 60 Gy / 30 # ( Veronesi et al )
  • 15.
  • 16.  
  • 17.
  • 18.
  • 19.
  • 21. IOERT Vs HDR IORT 45 – 120 min Total procedure time: 30-45 min TREATMENT RESULTS ARE EQUAL WITH REGARD TO LOCAL CONTROL, SURVIVAL AND COSMESIS. Portable, but requires shielding Logistical problems Custom made applicators for different anatomic locations Standard applicators for all patients Can be use in inaccessible sites Difficult to use in certain anatomic locations Not suitable Large tumor beds can be treated Lower dose at depth Higher dose at depth ( 2 cm ) 5 – 30 min Faster treatment time : 2-4 min > 100 % variation Better dose homogeneity: < 10% variation from surface to depth HDR IORT IOERT
  • 22.
  • 23.
  • 24.
  • 25.
  • 26.
  • 27.