This document discusses the effects of anesthetics on cerebral blood flow and cerebral metabolic rate of oxygen. It explains that anesthetics generally suppress brain metabolism and appetite, leading to decreased cerebral blood flow and intracranial pressure. Specific anesthetics like barbiturates, propofol, volatile agents, and nitrous oxide are discussed in terms of their effects on cerebral blood flow, cerebral metabolic rate, intracranial pressure, and other factors. The importance of maintaining proper cerebral perfusion pressure during neuroanesthesia is also emphasized.

1. EFFECTS OF ANESTHETICS ON CEREBRAL BLOOD FLOW & CMRO2 PRESENTER Dr Unnikrishnan P COORDINATOR Dr Linnette Morris MODERATORS Dr Ushakumari Dr Chitra

15. Propofol & brain protection

29. INHALED ANAESTHETICS

30. VOLATILE AGENTS….

31. EFFECTS @ DIFFERENT MACs

42. Summary of volatile agents MAJOR IMPACT ON CBF/CBV & ICP OCCURS WHEN WE EXCEED 1 MAC BECOMES SIGNIFICANT IF INTRACRANIAL COMPLIANCE IS ABNORMAL HERE, IT IS BETTER TO USE A PREDOMINANTLY INTRAVENOUS TECHNIQUE UNTIL THE POINT OF OPENING OF CRANIUM & DURA NET VASODILATORY EFFECT OF ISO/DES & SEVO LESS THAN HALO;SO IF ONE IS TO BE USED, PREFER THE FORMER ONES EFFECT OF HYPOCAPNOEA : HALOTHANE Vs ISO/DES/SEVO ENFLURANE IS EPILEPTOGENIC; SLIGHT RISK WITH SEVOFLURANE CO2 REACTIVITY AND AUTOREGULATION PRESERVED

46. MUSCLE RELAXANTS

48. Non depolarizing relaxants- histamine release

53. Textbook of neuroanesthesia & criticalcare/Basil F Matta SURGERY INDUCTION RELAXANT MAINTENANCE SUPRATENTORIAL ICSOL TPS/P’FOL ATRA/VEC/MIVA/ROC P’FOL-FENT / FENT- LD ISO / N2O- HD ISO VASCULAR Sx TPS/ETO/P’FOL VEC/ATRAC/PAN/? SCOLINE* P’FOL-OPIOID +/- VOL AGENT* ?N2O CAROTID Sx FENT/ETO/TPS/ P’FOL VEC FENT/ISO/N2O POST FOSSA OPIOID/TPS/ P’FOL NDMR VARIES ?N2O-PC/VAE ?VOL-TRANS PUL,SSEP NSx WITHOUT CRANIOTOMY FENT/TPS/P’FOL NDMR ISO WITH HYPOCAPNOEA Cx SPINE RSI-SCOLINE PED TPS/P’FOL/SEVO SUXA/NDMR N2O+LD ISO/SEV OR P’FOL i/FEN OR AIR+HD VA