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                Daniel J. Vreeman, PT, DPT, MSc	
                       Assistant Research Professor, Regenstrief Institute, Inc. 	
          Associate Director of Terminology Services, Indiana University School of Medicine	




Clinical LOINC Meeting | 01/27/2011	
                                     Copyright © 2011
Overview	
Origins of a Document Ontology	
HL7/LOINC Model	
Evaluation and Ongoing Development	
Future Directions
Origins of a Document
Ontology
Introduction	
Local systems have idiosyncratic names…	




 Outpatient Pain   Dr. Smith’s Tues     Chronic Pain
     Note	
        Pain Clinic Note	
      Clinic	



…need a common, controlled vocabulary
06/2000	
•  Document Ontology
   Task Force	

                           09/2003	
                           •  First Axis Values and LOINC
06/2005	
                     Codes	

•  Expanded SMD Domain	

                                        10/2007	
                                        •  Revised Axis
                                           Value Approval	




                             Ongoing	
                             •  Harmonization Efforts	
                             •  New Content Creation
Document Type Codes	
Provide consistent semantics for names of
documents exchanged b/w systems	
	

                                                                                                Preparation of
                                                Display	
                                         Templates	



                                                                      Organization	



                                               Retrieval	




Frazier P, Rossi-Mori A, Dolin RH, Alschuler L, Huff SM. The creation of an ontology of clinical document names. Stud Health Technol Inform. 2001;84(Pt 1):94-8.
What is a Document?	
a collection of information
Sections	
        	
Sentences	
        	
Sentences	
        	
Other content	
	
	
Different than a panel	
     Enumerated, discrete elements	
	
	
                                     an information
	
                                     collection
Clinical Notes	
Clinical Note   	
    	


    A clinical document, produced by clinicians
    spontaneously or in response to a request for
    consultation.	
    	
Clinical Report     	
    	


    A clinical document, produced in response to an
    order for a procedure.	
    	
	
Formal Document Ontology model and rules
apply to clinical notes, but not (yet) to reports.
Approach	
Empiric analysis of >2000
document names	
  – Mayo, 3M/Intermountain, VA in SLC, VA
    in Nashville	
	
Find the level of granularity that
best meets exchange use case
Ultra-specific local names	
•  Dr. Evil’s Friday Afternoon Pain
   Clinic Note	



        Commonly
        understood elements	
        •  Outpatient Pain Clinic
           Note
Local Codes and Names	
Still probably needed	
Can send both in HL7	
Mapping to a standard enables:	
 – Interoperability	
 – Aggregation
Document Ontology Model	
Multi-axial / Poly-hierarchical
Names are based on

expected information content

   NOT document format
Names Based on Content	
Same LOINC code for…	
	




     …if information content is the same
Not Part of the Name	
Author	
Location of service	
Date of service	
Status (e.g. signed, unsigned)	
Security/privacy flags (e.g. protected)	
Updates or amendments to a document
Assume that these other
important attributes would
be sent in different fields of
the message
Model of Document Names	
Subject Matter Domain	
 •  e.g. Cardiology, Pediatric Cardiology, Physical Therapy	

Role	
 •  Author training/professional classification (not @ subspecialty)	
 •  e.g. Physician, Nursing, Case Manager, Therapist, Patient	
Setting	
 •  Modest extension of CMS’s definition (not equivalent to location)	
 •  E.g. Inpatient hospital, Outpatient, Emergency Department	
Type of Service	
 •  Service or activity provided to patient	
 •  Eg. Consultation, History and Physical, Discharge Summary	
Kind of Document	
 •  General structure of the document	
 •  E.g. Note, Letter, Consent
Rules for
Constructing Names
1. Enumerated List	
Document names are constructed from
enumerated lists of values for each axis.
2. Document + One Other	
Document name needs specification of a Kind
of Document value and at least one of the
other four axes.	


  Component	
   •  <Type of Service>.<Kind of Document>	

   Property	
   •  Find	

     Time	
     •  Pt	

    System	
    •  <Setting>	

     Scale	
    •  Doc	

    Method	
    •  <SMD>.<Role>
3. Combinations	
Combinations from within an axis are allowed
where they make sense (SMD, Service).	




 Assessment                     Plan
Example LOINC Names	
Component	
                                 Prop	
   Time	
   System	
                    Scale	
   Method	
  

Group	
  counseling	
  note	
               Find	
     Pt	
     Inpa4ent	
  Hospital	
   Doc	
      {Provider}	
  
Evalua4on	
  and	
  management	
  note	
   Find	
      Pt	
     Outpa4ent	
               Doc	
     {Provider}	
  

Evalua4on	
  and	
  management	
  note	
   Find	
      Pt	
     {Se>ng}	
                 Doc	
     {Provider}	
  
History	
  and	
  physical	
  note	
        Find	
     Pt	
     {Se>ng}	
                 Doc	
     {Provider}	
  
Ini4al	
  evalua4on	
  note	
               Find	
     Pt	
     {Se>ng}	
                 Doc	
     Physician	
  




{curly braces} notation: send that content as                                                                 a
separate item in the message (field or segment).
Hierarchy	
Made a 1st pass Component hierarchy	
  –  Based on Type of Service Axis	
  –  Ignored Kind of Document	
Multi-axial hierarchy is auto-generated	
  –  Available as a separate download	
Custom hierarchies (e.g. context-
specific) ones are easily imagined
Hierarchy in RELMA
Evolution,
Evaluation	
We’re not done yet
Evolution	
Ongoing evaluation and evolution	
Exceptional contributions from Columbia
University and the VA	

  Expanded original SMD values with ABMS
 specialty names and iterative discussion
Iterative Evaluation
Case Study	
NYPH-CUMC
Case Study	
             SMD	
 Role	
 Setting	
 Type Service	
 Kind of Doc	
 Overall	
 Distinct 	
Original	
   26.7%	
 99.9%	
   99.9%	
   43.5%	
          100%	
       23.4% 	
   7.9%	
CDO	
                                                                 (n=894)	

Expanded	
 98.6%	
 100%	
      100%	
    99.9%	
          99.9%	
      98.5%	
    39.1%	
CDO	
                                                                 (n=935)	




 1.  Expanded CDO is better	
 2.  Many local documents map to 1 LOINC	
 3.  Inter-rater reliability was good	
 Hyun S, Shapiro JS, Melton G, Schlegel C, Stetson PD, Johnson SB, Bakken S. Iterative
 evaluation of the Health Level 7--Logical Observation Identifiers Names and Codes
 Clinical Document Ontology for representing clinical document names: a case report. J Am
 Med Inform Assoc. 2009 May-Jun;16(3):395-9.
Nursing	
           SMD	
 Role	
 Setting	
 Type Service	
 Kind of Doc	
 Overall	
 Distinct 	
SMD ++	
   74%	
   100%	
   100%	
     100%	
           100%	
       74.5%	
     33%	
CDO	
                                                                (n=94)	


Hyun S, Shapiro JS, Melton G, Schlegel C, Stetson PD, Johnson SB, Bakken S. Iterative
evaluation of the Health Level 7--Logical Observation Identifiers Names and Codes
Clinical Document Ontology for representing clinical document names: a case report. J Am
Med Inform Assoc. 2009 May-Jun;16(3):395-9.	




In a separate analysis…	

Section headings from nursing
documents that could be mapped
to existing LOINCs 	
Hyun S, Bakken S. Toward the creation of an ontology for nursing document sections:
mapping section names to the LOINC semantic model. AMIA Annu Symp Proc. 2006:364-8.
Case Study	
German University Hospital
German University Hospital	
                  Used LOINC v2.24 (original DocOnt terms)	

86 Document Types (1.2 mil documents)	

                   12%	
                                                       Mapped to LOINC	


                               44%	
                   Not specific enough mapping	
                  44%	
                                                       No LOINC match	



Dugas M, Thun S, Frankewitsch T, Heitmann KU. LOINC codes for hospital information
systems documents: a case study. J Am Med Inform Assoc. 2009 May-Jun;16(3):400-3.
German University Hospital	




  LOINC codes that existed for
documents in their set (by volume)
Ongoing Development
A Work-in-Progress	
	
LOINC User’s Guide is definitive
source for current policy	
	
	
Collaboration/discussion	
  –  Clinical LOINC Meetings	
  –  HL7 SDTC	
  –  Online
Future Directions
Future Directions	
More v1 and v2 axis value harmonization	
Axis definitions	
Extension to other Kind of Documents	
Empiric analysis of document contents

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2011 01 27 - Clinical LOINC Tutorial - Documents

  • 1. Documents Daniel J. Vreeman, PT, DPT, MSc Assistant Research Professor, Regenstrief Institute, Inc. Associate Director of Terminology Services, Indiana University School of Medicine Clinical LOINC Meeting | 01/27/2011 Copyright © 2011
  • 2. Overview Origins of a Document Ontology HL7/LOINC Model Evaluation and Ongoing Development Future Directions
  • 3. Origins of a Document Ontology
  • 4. Introduction Local systems have idiosyncratic names… Outpatient Pain Dr. Smith’s Tues Chronic Pain Note Pain Clinic Note Clinic …need a common, controlled vocabulary
  • 5. 06/2000 •  Document Ontology Task Force 09/2003 •  First Axis Values and LOINC 06/2005 Codes •  Expanded SMD Domain 10/2007 •  Revised Axis Value Approval Ongoing •  Harmonization Efforts •  New Content Creation
  • 6. Document Type Codes Provide consistent semantics for names of documents exchanged b/w systems Preparation of Display Templates Organization Retrieval Frazier P, Rossi-Mori A, Dolin RH, Alschuler L, Huff SM. The creation of an ontology of clinical document names. Stud Health Technol Inform. 2001;84(Pt 1):94-8.
  • 7. What is a Document? a collection of information
  • 8. Sections Sentences Sentences Other content Different than a panel Enumerated, discrete elements an information collection
  • 9. Clinical Notes Clinical Note A clinical document, produced by clinicians spontaneously or in response to a request for consultation. Clinical Report A clinical document, produced in response to an order for a procedure. Formal Document Ontology model and rules apply to clinical notes, but not (yet) to reports.
  • 10. Approach Empiric analysis of >2000 document names – Mayo, 3M/Intermountain, VA in SLC, VA in Nashville Find the level of granularity that best meets exchange use case
  • 11. Ultra-specific local names •  Dr. Evil’s Friday Afternoon Pain Clinic Note Commonly understood elements •  Outpatient Pain Clinic Note
  • 12. Local Codes and Names Still probably needed Can send both in HL7 Mapping to a standard enables: – Interoperability – Aggregation
  • 13. Document Ontology Model Multi-axial / Poly-hierarchical
  • 14. Names are based on expected information content NOT document format
  • 15. Names Based on Content Same LOINC code for… …if information content is the same
  • 16. Not Part of the Name Author Location of service Date of service Status (e.g. signed, unsigned) Security/privacy flags (e.g. protected) Updates or amendments to a document
  • 17. Assume that these other important attributes would be sent in different fields of the message
  • 18. Model of Document Names Subject Matter Domain •  e.g. Cardiology, Pediatric Cardiology, Physical Therapy Role •  Author training/professional classification (not @ subspecialty) •  e.g. Physician, Nursing, Case Manager, Therapist, Patient Setting •  Modest extension of CMS’s definition (not equivalent to location) •  E.g. Inpatient hospital, Outpatient, Emergency Department Type of Service •  Service or activity provided to patient •  Eg. Consultation, History and Physical, Discharge Summary Kind of Document •  General structure of the document •  E.g. Note, Letter, Consent
  • 20. 1. Enumerated List Document names are constructed from enumerated lists of values for each axis.
  • 21. 2. Document + One Other Document name needs specification of a Kind of Document value and at least one of the other four axes. Component •  <Type of Service>.<Kind of Document> Property •  Find Time •  Pt System •  <Setting> Scale •  Doc Method •  <SMD>.<Role>
  • 22. 3. Combinations Combinations from within an axis are allowed where they make sense (SMD, Service). Assessment Plan
  • 23. Example LOINC Names Component   Prop   Time   System   Scale   Method   Group  counseling  note   Find   Pt   Inpa4ent  Hospital   Doc   {Provider}   Evalua4on  and  management  note   Find   Pt   Outpa4ent   Doc   {Provider}   Evalua4on  and  management  note   Find   Pt   {Se>ng}   Doc   {Provider}   History  and  physical  note   Find   Pt   {Se>ng}   Doc   {Provider}   Ini4al  evalua4on  note   Find   Pt   {Se>ng}   Doc   Physician   {curly braces} notation: send that content as a separate item in the message (field or segment).
  • 24. Hierarchy Made a 1st pass Component hierarchy –  Based on Type of Service Axis –  Ignored Kind of Document Multi-axial hierarchy is auto-generated –  Available as a separate download Custom hierarchies (e.g. context- specific) ones are easily imagined
  • 27. Evolution Ongoing evaluation and evolution Exceptional contributions from Columbia University and the VA Expanded original SMD values with ABMS specialty names and iterative discussion
  • 29. Case Study SMD Role Setting Type Service Kind of Doc Overall Distinct Original 26.7% 99.9% 99.9% 43.5% 100% 23.4% 7.9% CDO (n=894) Expanded 98.6% 100% 100% 99.9% 99.9% 98.5% 39.1% CDO (n=935) 1.  Expanded CDO is better 2.  Many local documents map to 1 LOINC 3.  Inter-rater reliability was good Hyun S, Shapiro JS, Melton G, Schlegel C, Stetson PD, Johnson SB, Bakken S. Iterative evaluation of the Health Level 7--Logical Observation Identifiers Names and Codes Clinical Document Ontology for representing clinical document names: a case report. J Am Med Inform Assoc. 2009 May-Jun;16(3):395-9.
  • 30. Nursing SMD Role Setting Type Service Kind of Doc Overall Distinct SMD ++ 74% 100% 100% 100% 100% 74.5% 33% CDO (n=94) Hyun S, Shapiro JS, Melton G, Schlegel C, Stetson PD, Johnson SB, Bakken S. Iterative evaluation of the Health Level 7--Logical Observation Identifiers Names and Codes Clinical Document Ontology for representing clinical document names: a case report. J Am Med Inform Assoc. 2009 May-Jun;16(3):395-9. In a separate analysis… Section headings from nursing documents that could be mapped to existing LOINCs Hyun S, Bakken S. Toward the creation of an ontology for nursing document sections: mapping section names to the LOINC semantic model. AMIA Annu Symp Proc. 2006:364-8.
  • 32. German University Hospital Used LOINC v2.24 (original DocOnt terms) 86 Document Types (1.2 mil documents) 12% Mapped to LOINC 44% Not specific enough mapping 44% No LOINC match Dugas M, Thun S, Frankewitsch T, Heitmann KU. LOINC codes for hospital information systems documents: a case study. J Am Med Inform Assoc. 2009 May-Jun;16(3):400-3.
  • 33. German University Hospital LOINC codes that existed for documents in their set (by volume)
  • 35. A Work-in-Progress LOINC User’s Guide is definitive source for current policy Collaboration/discussion –  Clinical LOINC Meetings –  HL7 SDTC –  Online
  • 37. Future Directions More v1 and v2 axis value harmonization Axis definitions Extension to other Kind of Documents Empiric analysis of document contents