1. Formula 4
Ginseng dry extract
Nigella sativa seeds
Ginseng dry extract Nigella sativa seeds
1- Different
Panax ginseng Nigella sativa
names of
(traditional Chinese herb) Black seed
drug:
2- Part
Roots Seeds
used:
1- Essential (volatile) oils
Thymoquinone
2- Fixed (fatty) oils:
1- Triterpenoid saponin
Omega 3 = linolenic acid
glycosides
Omega 6 = linoleic acid
3- Active (Ginsenosides =
constituent: Panaxosides)
NB: Nigella is very rich in
2- Polysaccharide glycans
nutrients (sugars, all essential
(Panaxans)
amino acids, minerals,
vitamins…) that is why it has a
very high nutritional value.
1- Adaptogen
2- Immunostimulant
4- Medicinal 3- Tonic (decreases fatigue and weakness)
uses:
4- Respiratory problems
4- Hypoglycemic
5- Nutritional supplement
As immunostimulant:
Ginsenosides increase 1- Omega 3 and Omega 6 are
corticosteroids à enhance necessary for forming
adaptogenic effect prostaglandins (PGs) which
strengthen the immune system
5- Mode of -Ginseng augments and prevent infection.
Action: adrenal synthesis of
corticosteroids which play 2- Raises interferon production
a significant role in the
adaptation capabilities of 3- Increases cells of the
the body to stress immune system (T-cells,
natural killer cells and
cytokines).
1
2. Long term use causes
Ginseng abuse
syndrome (CNS
6- Side excitation, nervousness,
Effects: insomnia, elevated blood
pressure…) especially
when used with CNS
stimulants.
-Nigella seed extract (4:1)
standardized to contain 5%
thymoquinone used in dose of
50-57 mg in the form of capsules
Daily dose is 1-2 gm crude
-Also available in the form of oil
7- drug or 200 mg of a
used internally with meals or
Information concentrated aqueous
externally as creams, gels or
of any extract standardized to
lotions.
standardize contain 4% ginsenosides
d extract: in the form of infusion,
NB:
capsule or extract.
-Nigella oil should be
refrigerated after opening to
avoid rancidity.
-Nigella can't be used as tea as
thymoquinone is water insoluble.
2
3. Adaptogens
1- Definition:
Plants which increase the ability of the organism to adapt to different
stressors, balance the immune system, increase performance and vitality
and accelerate convalescence.
-Explaining the effect of adaptogens is difficult as they influence each
individual differently.
2- Properties of adaptogens:
Adaptogens are non-specific in action i.e. they increase resistance of
the body to a broad spectrum of harmful factors (physical, chemical,
biological…)
-Adaptogens have a normalizing effect on the body i.e. tone down by
hyperfunctioning systems and strengthen hypofunctioning systems
Difference between Adaptogens and CNS stimulants
In stimulants, the level of performance reaches its maximum followed
by a corresponding decrease below the average level of performance with a
feeling of exhaustion.
3
