dr faeza pathology

1. Oral PathologyOral Pathology
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2. ORAL PATHOLOGY
• INFECTIONS:
HSV, VIRAL, FUNGI
• LEUKOPLAKIA/”
• SQUAMOUS TUMORS:
• ODONTOGENIC
CYSTS/TUMORS

3. Herpetic vesicles
Herpesvesicle with ulceration & secondary inflammation

4. Herpes Zoster “shingles”

5. EBV “glandular fever”.

6. Monilia, thrush-mouth, candida

7. •Syphilis “1, 2, 3”.

8. Aphthous ulcer
Aphthous ulcer. Single ulceration with
an erythematous halo surrounding a
yellowish fibrinopurulent membrane.

9. Behcet's disease
hypopyon.
Oral Ulcer.

10. Pharyngitis
Oropharynx

11. Tonsillitis & peritonsillar abscess “Quinsy”
Oropharynx

12. Diphtheria
Oropharynx

13. Oral Pathology
Skin diseases can affect oral mucosa
Lichen planus Erythema multiforme
Pemphigus vulgaris
Pemphigoid.
Pigmentation of lip & oral mucosa.
Peutz–Jeghers syndrome

14. Oral Pathology
Polypoid nodules in the mouth
• Pyogenic granuloma.
• Fibroepithelial polyp
Leukoplakia.
Sq C Ca.

15. “Irritation” Fibroma
Fibroma. Smooth pink exophytic nodule
on the buccal mucosa.

16. PYOGENIC
GRANULOMA
Pyogenic granuloma. Erythematous,
hemorrhagic, and exophytic mass
arising from the gingival mucosa

17. • Leukoplakia is defined by the WHO as;
• “a white patch or plaque that cannot be
scraped off and cannot be
characterized clinically or pathologically
as any other disease.”

18. • Erythroplakia (red area), associated with a
greater risk of malignant transformation than
leukoplakia.
• 40 and 70 years, 2 : 1 male preponderance.
• Tobacco is the most common risk factor for
leukoplakia and erythroplakia.

19. leukoplakia

20. Tobacco
Alcohol
HPV
Family history
chronic irritation
95% are Sq C Ca.

21. the sites of origin of Sq C Ca of the oral
cavity, in numerical order of frequency
the favored locations are the ventral surface of
the tongue, floor of the mouth, lower lip, soft
palate, and gingiva

23. 3 exophytic masses “SqcCa”,
the hyperkeratotic area is lichen
planus.

24. ODONTOGENIC
CYSTS/TUMORS
• INFLAMMATORY CYSTS (e.g.,
“Radicular”[periapical] most common)
• DEVELOPMENTAL CYSTS
• MALIGNANT TUMORS of ODONTOGENIC ORIGIN
(AMELOBLASTOMAS) (rare)

25. Odontogenic Cysts
• Epithelial-lined cysts are
common in the jaws
• derived from remnants of
odontogenic epithelium
present within the jaws.
• these cysts are;
1. inflammatory or
2. developmental

26. Salivary glands

27. Salivary glands

29. Mucocele of an accessory salivary gland duct

30. Mucocele of an accessory salivary gland duct

31. Sialadenitis

33. DISEASES OF SALIVARY GLANDS
• Xerostomia
• autoimmune disorder Sjِgren syndrome
• Rtx
• Drugs; anticholinergic, antidepressant/ antipsychotic,
diuretic, antihypertensive, sedative, muscle relaxant,
analgesic, & antihistaminic agents
• dental caries & candidiasis, difficulty in swallowing &
speaking

34. Oral Pathology
 Salivary glands tumors;
• are mostly Benign & affect parotid.parotid.
- “Pleomorphic adenoma” or “ Mixed tumor”
- Adenolymphoma or “Warthin’s tumor” of parotid.
• Malignant;
• Affect Minor salivary glands.
• “Mucoepidermoid ca”.
• “Adenoid cystic carcinoma”
• Others.

35. P
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36. Pleomorphic Adenoma

37. PLEOMORPHIC ADENOMA
i.e., MIXED TUMOR

38. Pleomorphic Adenoma
• pleomorphic
adenoma contains
both epithelial (E) and
stromal (S)
components.

39. Pleomorphic Adenoma
• This neoplasm is
typically
encapsulated,
although tumor
islands may be
found within the
fibrous capsule.

40. WARTHIN TUMOR

41. Warthin's Tumor
• Warthin's tumor
(benign papillary
cystadenoma
lymphomatosum)
• the second most
common benign
tumor of the parotid
gland

42. Mucoepidermoid Ca.
• MECs contain two major
elements:
• mucin-producing cells and
epithelial cells of the
epidermoid variety
• Divided into low-grade (well
differentiated), & High-grade
(poorly differentiated).

43. Adenoid Cystic Carcinoma
• Adenoid cystic carcinoma
with Swiss cheese
pattern.
• It is the second-most
common malignant tumor
of the salivary glands.
• ACC is the most
common malignant tumor
found in the
submandibular,
sublingual, and minor
salivary glands.

44. Adenoid Cystic Carcinoma
• Nerve (N) invaded by
adenoid cystic
carcinoma
(the blue area
surrounding the
nerve).
• Spread may occur by
emboli along the
nerve lymphatics

45. • Behcet's (beh-CHETS) disease, also called Behcet's
syndrome, is a rare disorder that causes inflammation in
blood vessels.
• The signs and symptoms of Behcet's disease — which
may include mouth sores, eye inflammation, skin rashes
and lesions, and genital sores — vary from person to
person and may come and go on their own.
• The exact cause of Behcet's is unknown, but it may be
an autoimmune disorder,
• Both genetic and environmental factors may be
responsible for Behcet's disease.
• Treatment aims to reduce the signs and symptoms of
Behcet's disease and to prevent serious complications,
such as blindness.