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10.6.2009

The Coalition For Public Health: "Past,
Present and Future; what awaits the kids
in the Haifa–bay area?"
 Taken on summer
     22.6.2006
    Ella Nave




Ella Nave, M.P.H - Coalition for Public Health
James Krikun, PhD.- Coalition for Public Health

Special Thanks to Dr. Moshe Shirav Schwartz and Dr. Ziona Haklai
Dr. James Krikun and Neveen Matar Dahdal
In the past…Pollution

Massive Exposure of the Local Population to extremely high levels of
pollutants, such as: Transition Metals, Volatile Organic Compounds, etc.
Factories working with no emission control means. Considering the unique
topography, low stack height, and meterology of Haifa, pollutants are “stuck”

On the Other hand, Environmental Epidemiological Research is limited due
to lack of Accurate Exposure Assessment (Only SO2 and NO2 monitored
until 90's, no volatiles measured in the neighboring cities etc), diffucult
pollutant modelling etc.




                           ©   2006
In the past…Research

Even though this, Associations are found in the 80's between high
pollution areas and several respiratory diseases, compared with low
pollution areas. For Instance, a local research found elevated risks for more
than 3 colds per year, Bronchitis, and suptum without cold.)
Goren A.I. et al. 1990 Prevalence of Respiratory Conditions among Schoolchildren Exposed to Different levels of
Air Pollutants in the Haifa Bay Area, Israel.


Another research: “The effects of exposure to air pollution (defined by levels of
SO2) were also studied in a representative sample of over 3,500 households in
the greater Haifa area.. The sample was drawn from 16 high and low pollution
neighborhoods .... A very significant relationship was found between
levels of pollution in residential and work areas and self-reported
respiratory symptoms and diseases…


Epstein et al. 1991 Air pollution and morbidity in the Haifa region Area, Israel. Harefuah 1991 Jun 16;120(12):709-14.
In the past…Research


    Also found in the 80's – are high levels of blood lead in high pollution
    areas compared with low pollution areas.


 Richter ED, Berant M, et al. Blood zinc protoporphyrin levels in the children and
   wives of lead battery workers: a preliminary report. Isr. J. Med Sci. 1985
   Sep;21(9):761-4.
Richter ED, Berant M, et al. Zinc protoporphyrin levels in children in Haifa: a
   pilot study. Sci. Total Environ. 1986 Jan; 48(1-2):109-21.
.
Are kids more vulnerable?
YES. The Embryo, child and teenager is more affected by environmental pollution, and
specifically, by air pollution. Some reasons for that are:

1. Embryos have exposure windows, when exposure to environmental pollutants
would be more harmful than at different timing, For instance: when bronchi or brain
are developed.

2. Lungs - babies have less alveoli than 4 year old kids. Also, the ratio of Surface to
body mass is greater in kids, enabling them to breath 50% more air per kg than
adults ! If lung functions are decreased due to air pollution, the heart might be also
affected.

3. The body tissues of a child are still developing, and therefore are more
vulnerable to pollutants harming DNA etc.

4. A child's Immune system as not yet developed at birth, and so more affected by
environmental toxins than in adulthood.

5. Liver Enzymes less effective than at adulthood, therefore- detoxifying toxins is
more of a challenge to them.
Epidemiology at Present…

            Exposure ?   Morbidity ?

Are kids in Haifa-bay area
still exposed?       Are kids in Haifa-bay area
                     any sicker than in other
                     places?


Only hints will be given, your answer is needed !
Are kids in Haifa-bay area
               still exposed?
                          YES.

      These Pictures were taken April 2009…
             Fact is that this is NOT a dust storm.
01/04/09   14:30   PM2.5 level were 67micrograms/m3 in Neve Shannan, 55 in K. Tivon and 41 in Ahuza
Are kids in Haifa-bay area
                still exposed after 2000?
                        YES .    How do we know?

1. Data from Monitoring Stations of Haifa District Municipal Association
   for the Environment– 80’s-2009 showing Long term exposure to high
   levels of particulate matter and other pollutants. According to these,
   Industry and Electricity production are the major polluters of Haifa
   Bay area with Particulates, and VOC’s, which we know today is the
   more problematic fraction of air pollution.

2. Data from Geological Surveys – 2007 (validating long term exposure to
   transition metals, as detected by high anthropogenic attributed ground
   levels)

3. Data from The Israeli Environmental Protection Agency – 4 samples
   in 20 spots were carried out in 2007-2008, some air samples showing
   exceeding levels of carcinogens in schools, residential neighbourhoods, etc.
‫‪1. Rate of Particulate Matter Emission (PM10) from‬‬
 ‫‪Industries and Electricity Production in Comparison to‬‬
 ‫‪Mobile Sources years 2002-2007 Ton/year – Haifa area‬‬
                               ‫,‬
                         ‫(‬           ‫7002-2002 )‬          ‫,‬
                                                              ‫5.2‬
                       ‫0081‬
                                         ‫4951‬
                       ‫0061‬   ‫0141‬                            ‫7341‬        ‫4.4‬
                       ‫0041‬                        ‫5031‬                               ‫8‬
                       ‫0021‬                                                ‫2101‬
                                   ‫209‬      ‫469‬
                       ‫0001‬
                        ‫008‬                           ‫666‬                             ‫536‬
                                                                    ‫165‬
                        ‫006‬
                   ‫/‬




                       ‫004‬                                                      ‫822‬
                       ‫002‬                                                                  ‫97‬
                         ‫0‬
                               ‫2002‬       ‫3002‬      ‫4002‬        ‫5002‬        ‫6002‬      ‫7002‬


   ‫ניתן לראות: יחסי הפליטות תחבורה לתעשיה הן לרעת התעשיה ויצור החשמל. התעשייה ויצור החשמל באזור‬
     ‫מפרץ חיפה פולטים יותר חלקיקים מסוג 01‪ PM‬מאשר סה"כ כל סקטור התחבורה בשנים 7002-2002. בין‬
‫השנים 2002 ל-7002 הייתי ירידה בקצב פליטות החומר החלקיקים בשני הסקטורים. )מקור: דוח"ות איגוד ערים‬
                                                                           ‫חיפה לשנים 7002-8991(‬
                                                                            ‫-8991‬
‫‪Source: Annual reports, Haifa District Municipal Association for the Environment‬‬
‫‪1. Rate of Volatile Organic Compounds Emissions from‬‬
‫‪Industries and Electricity Production in Comparison to Mobile‬‬
‫‪Sources years 2002-2007 Ton/year -Haifa area‬‬

                 ‫,‬                           ‫)‪(VOC's‬‬                     ‫¯ 2‬
                         ‫(‬           ‫7002-2002 )‬         ‫,‬
                                                                                   ‫1.3‬
     ‫‪VOCs‬‬
                         ‫00041‬      ‫37431‬    ‫37431‬     ‫37431‬    ‫37431‬     ‫1.3‬
     ‫,‪Industry‬‬
    ‫‪Electriciy‬‬
                                                                                      ‫58.1‬
   ‫‪production‬‬
                         ‫00021‬                                           ‫5.23901‬
                                                                                     ‫6989‬
                         ‫00001‬                           ‫9388‬
                             ‫0008‬     ‫1727‬     ‫1147‬
                                                                  ‫1366‬
      ‫‪VOCs‬‬                   ‫0006‬                                                        ‫4435‬
                     ‫/‬




‫‪Transportation‬‬               ‫0004‬                                           ‫5.1253‬

                             ‫0002‬
                                     ‫2002‬     ‫3002‬      ‫4002‬     ‫5002‬      ‫6002‬       ‫7002‬


  ‫ניתן לראות: יחסי הפליטות תחבורה לתעשיה הן לרעת התעשיה ויצור החשמל. התעשייה ויצור‬
  ‫החשמל באזור מפרץ חיפה פולטים כמעט פי 2 יותר תרכובות אורגניות נדיפות מאשר סה"כ כל‬
 ‫סקטור התחבורה בשנים 7002-4002. אפשר להתייחס לירידה בסקטור התעשיה ויצור החשמל‬
     ‫בין השנים 4002 ל-7002 כאל ירידה ממצב גרוע מאוד, למצב גרוע. )מקור: דוח"ות איגוד‬
                                                         ‫-2002‬
                                                        ‫ערים חיפה לשנים 7002-2002(‬
Just for general knowledge….


Does any of you know what weighs 13,000 tons?




Answer: 1 bus without passengers is ~13 tons.
Imagine 1000 buses – this is the weight of
VOC’s spreading in yearly between 2002-2005
on your hometowns.
Remember, that some Volatiles show no
threshold limit for causation of cancer…
1. Annual averages of Particulate Matter Emission (PM10)
concentrations - Comparison between different areas of the
bay - years 2006-2007
                             2007 2006          (PM10)                 ¯
                                         micrograms/m3
                   70
                                               59
                   60                55 53
                        48                          49             50 48
          ¯




                   50        42                          42
                                                              39
   2006            40
   2007            30
          P M 10




                   20
                   10
                   0
                                                                     ' -
2. Validation of
Environmental Exposure to
Transition Metals
From Soil Sampling
Manganese/Iron Ratio
Anthropogenic




      =       =   *
          ¯
2. Validation of
Environmental Exposure to
Metals From Soil Sampling
Cadmium/P205
Anthropogenic




            =    *
3. Data from The Israeli Environmental Protection Agency –
Benzene Concentrations in several educational institutions and
schools carried out in 2007-2008,
                      K. Haim, K. Binyamin (Ata), Neve Shannan, Kfar Hasidim
                                20
                                                                                               18.373
                                19
                                18
                                              16.495                      16.24
                                17   16.006
                                16
                                15                                                13.67
        ( "   )
                          ¯


                  ¯
                                14
                                13
              "                 12
                                                       10.485
                                11
                                10
                                 9
                                 8
                                                          6.519
                                 7
                          " /




                                 6
        (     )
                                 5
                                 4
                                 3
                                                                  0.44
                                 2                                                           0.404
                                                                                                         0.523
                                                                                                                       0.559
                                 1                                   0.382 0.499 0.356                             0.318
                                                0 0.162                                   0.097    0.083       0.153        0.153
                                 0
                                               07-                       07-                  08                     08-

                      =   *

 some air samples showing exceeding levels of carcinogens in schools, residential
 neighborhoods, etc.
3. Data from The Israeli Environmental Protection Agency –
Formaldehyde Concentrations in several educational institutions,
and schools carried out in 2007-2008,
                K. Haim, K. Binyamin (Ata), Kfar Hasidim
                                         6

                                                    4.94


                                   ¯
                                         5
      ( "   )
                           ¯                               3.81
                                         4
            "                                                                        3.328
                                                       2.99
                                         3    2.74            2.63    2.829 2.939                           2.765 2.862
                                                                                          2.554
                                             2.19
                                                                                  1.891
      (     )                            2                           1.722
                                                                                                  1.516 1.64 1.549
                                   " /




                                         1


                                         0
                                               07-                           08                           08

                   =           *
                       =             *
 all air samples shown exceed levels of carcinogens allowed. Don’t forget, these are
 schools, residential neighborhoods, etc.
3. Data from The Israeli Environmental Protection Agency –
Dioxins Concentrations in several educational institutions, and
schools carried out in 2007-2008,
     K. Haim (almost 60 phemtograms),
     K. Binyamin (Ata) – 60-70 phemtograms

                                   0.08
                                   0.07
                                   0.06
                             ¯

      ( "   )                      0.05
                         ¯         0.04
            "                      0.03
                             " /




                                   0.02
                                   0.01
      (     )                        0
                                          2007   2007         2008      2008
                     =        *



 These are considered in the world literature high levels of Dioxins.
What does the World Health Organization
declare about air pollution and Causality?
  “Effects for which evidence is sufficient to infer a causal relationship
  with exposure to air pollution
  There is now substantial evidence on the adverse effects of air pollution on different pregnancy
  outcomes and infant health. The evidence shows that air pollution, with concentrations typical of many
  European cities, increases the risk of death from respiratory causes in the postneonatal period.
  The evidence also shows a relationship between exposure to ambient air pollutants and adverse effects
  on the development of lung function. Reversible lung function deficits, chronically reduced lung
  growth rates and lower lung function levels are associated with exposure to air pollution. Moreover,
  the evidence shows clearer relationships for particulate matter and traffic-related air
  pollution (indicated by nitrogen dioxide) than for other pollutants. Based on current knowledge, air
  pollutants seem to interact with other environmental factors, such as allergens, viruses and diet, that
  influence the overall impact of air pollutants on children's health.
  The report concludes that there is a causal relationship between exposure to air
  pollutants and aggravation of asthma. The evidence is also sufficient to
  assume a causal link between exposure to particulate matter and increased
  prevalence and incidence of cough and bronchitis.
  In particular, such environmental contaminants as certain heavy metals and persistent
  organic pollutants show significant adverse effects on the development of the
  nervous system and behaviour in children. Also, there is sufficient evidence of a causal
  relationship between exposure to lead and neurobehavioral deficits in children, in terms of cognitive
   impairment."
http://www.euro.who.int/HEN/Syntheses/short/20060224_1?PrinterFriendly=1&who
There are also good news:
We also know that….

Reduction of particulate air pollution levels
improves the health and lung functions of
children and adults, and saves from mortality.
(Laden et al., Pope et al., Avol et al.)

This is a scientifically approved fact (see WHO
report).
Epidemiology at Present…

                    Morbidity ?

                  Are kids in Haifa-bay area
                  any sicker than in other
                  places?



Only hints will be given, your answer is needed !
General Hospitalizations of Children ages 0-4
 presented at precentage above/under the country’s ,
 average (o line) at several cities and districts in
 years 1998-2002.




Source: Lamas
(            )
Hospitalizations due to Aggravation of Asthma of
Children 0-4 presented at rate/100,000 in several
nafot in years 2004-2006.

                     1800
                     1600
                     1400
                     1200
    2004
                     1000
    2005
                      800
    2006              600
                      400
           100,000




                      200
                        0
                            ¯



                                    ¯




                                                 -
                                         -


Source: Ministry of Health, at request
This is not the whole picture…
       Innovative Studies
   New Air Pollution Cohorts
► Effects on Children’s Cognition through the
Olfactory nerve and circulation to brain.
► Effects on Obesity (PCB’s)
► Effects on the risk of developing Asthma in 1st
year of life.
► Effects on DNA methylation
                              (BAMSE)       -       •
what awaits the kids
         in the Haifa–bay area?




         It’s in our hands to decide!
         Change Policy-altogether with
?‫שאלות‬
               better Research !

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  • 1. 10.6.2009 The Coalition For Public Health: "Past, Present and Future; what awaits the kids in the Haifa–bay area?" Taken on summer 22.6.2006 Ella Nave Ella Nave, M.P.H - Coalition for Public Health James Krikun, PhD.- Coalition for Public Health Special Thanks to Dr. Moshe Shirav Schwartz and Dr. Ziona Haklai Dr. James Krikun and Neveen Matar Dahdal
  • 2. In the past…Pollution Massive Exposure of the Local Population to extremely high levels of pollutants, such as: Transition Metals, Volatile Organic Compounds, etc. Factories working with no emission control means. Considering the unique topography, low stack height, and meterology of Haifa, pollutants are “stuck” On the Other hand, Environmental Epidemiological Research is limited due to lack of Accurate Exposure Assessment (Only SO2 and NO2 monitored until 90's, no volatiles measured in the neighboring cities etc), diffucult pollutant modelling etc. © 2006
  • 3. In the past…Research Even though this, Associations are found in the 80's between high pollution areas and several respiratory diseases, compared with low pollution areas. For Instance, a local research found elevated risks for more than 3 colds per year, Bronchitis, and suptum without cold.) Goren A.I. et al. 1990 Prevalence of Respiratory Conditions among Schoolchildren Exposed to Different levels of Air Pollutants in the Haifa Bay Area, Israel. Another research: “The effects of exposure to air pollution (defined by levels of SO2) were also studied in a representative sample of over 3,500 households in the greater Haifa area.. The sample was drawn from 16 high and low pollution neighborhoods .... A very significant relationship was found between levels of pollution in residential and work areas and self-reported respiratory symptoms and diseases… Epstein et al. 1991 Air pollution and morbidity in the Haifa region Area, Israel. Harefuah 1991 Jun 16;120(12):709-14.
  • 4. In the past…Research Also found in the 80's – are high levels of blood lead in high pollution areas compared with low pollution areas. Richter ED, Berant M, et al. Blood zinc protoporphyrin levels in the children and wives of lead battery workers: a preliminary report. Isr. J. Med Sci. 1985 Sep;21(9):761-4. Richter ED, Berant M, et al. Zinc protoporphyrin levels in children in Haifa: a pilot study. Sci. Total Environ. 1986 Jan; 48(1-2):109-21. .
  • 5. Are kids more vulnerable? YES. The Embryo, child and teenager is more affected by environmental pollution, and specifically, by air pollution. Some reasons for that are: 1. Embryos have exposure windows, when exposure to environmental pollutants would be more harmful than at different timing, For instance: when bronchi or brain are developed. 2. Lungs - babies have less alveoli than 4 year old kids. Also, the ratio of Surface to body mass is greater in kids, enabling them to breath 50% more air per kg than adults ! If lung functions are decreased due to air pollution, the heart might be also affected. 3. The body tissues of a child are still developing, and therefore are more vulnerable to pollutants harming DNA etc. 4. A child's Immune system as not yet developed at birth, and so more affected by environmental toxins than in adulthood. 5. Liver Enzymes less effective than at adulthood, therefore- detoxifying toxins is more of a challenge to them.
  • 6. Epidemiology at Present… Exposure ? Morbidity ? Are kids in Haifa-bay area still exposed? Are kids in Haifa-bay area any sicker than in other places? Only hints will be given, your answer is needed !
  • 7. Are kids in Haifa-bay area still exposed? YES. These Pictures were taken April 2009… Fact is that this is NOT a dust storm. 01/04/09 14:30 PM2.5 level were 67micrograms/m3 in Neve Shannan, 55 in K. Tivon and 41 in Ahuza
  • 8. Are kids in Haifa-bay area still exposed after 2000? YES . How do we know? 1. Data from Monitoring Stations of Haifa District Municipal Association for the Environment– 80’s-2009 showing Long term exposure to high levels of particulate matter and other pollutants. According to these, Industry and Electricity production are the major polluters of Haifa Bay area with Particulates, and VOC’s, which we know today is the more problematic fraction of air pollution. 2. Data from Geological Surveys – 2007 (validating long term exposure to transition metals, as detected by high anthropogenic attributed ground levels) 3. Data from The Israeli Environmental Protection Agency – 4 samples in 20 spots were carried out in 2007-2008, some air samples showing exceeding levels of carcinogens in schools, residential neighbourhoods, etc.
  • 9. ‫‪1. Rate of Particulate Matter Emission (PM10) from‬‬ ‫‪Industries and Electricity Production in Comparison to‬‬ ‫‪Mobile Sources years 2002-2007 Ton/year – Haifa area‬‬ ‫,‬ ‫(‬ ‫7002-2002 )‬ ‫,‬ ‫5.2‬ ‫0081‬ ‫4951‬ ‫0061‬ ‫0141‬ ‫7341‬ ‫4.4‬ ‫0041‬ ‫5031‬ ‫8‬ ‫0021‬ ‫2101‬ ‫209‬ ‫469‬ ‫0001‬ ‫008‬ ‫666‬ ‫536‬ ‫165‬ ‫006‬ ‫/‬ ‫004‬ ‫822‬ ‫002‬ ‫97‬ ‫0‬ ‫2002‬ ‫3002‬ ‫4002‬ ‫5002‬ ‫6002‬ ‫7002‬ ‫ניתן לראות: יחסי הפליטות תחבורה לתעשיה הן לרעת התעשיה ויצור החשמל. התעשייה ויצור החשמל באזור‬ ‫מפרץ חיפה פולטים יותר חלקיקים מסוג 01‪ PM‬מאשר סה"כ כל סקטור התחבורה בשנים 7002-2002. בין‬ ‫השנים 2002 ל-7002 הייתי ירידה בקצב פליטות החומר החלקיקים בשני הסקטורים. )מקור: דוח"ות איגוד ערים‬ ‫חיפה לשנים 7002-8991(‬ ‫-8991‬ ‫‪Source: Annual reports, Haifa District Municipal Association for the Environment‬‬
  • 10. ‫‪1. Rate of Volatile Organic Compounds Emissions from‬‬ ‫‪Industries and Electricity Production in Comparison to Mobile‬‬ ‫‪Sources years 2002-2007 Ton/year -Haifa area‬‬ ‫,‬ ‫)‪(VOC's‬‬ ‫¯ 2‬ ‫(‬ ‫7002-2002 )‬ ‫,‬ ‫1.3‬ ‫‪VOCs‬‬ ‫00041‬ ‫37431‬ ‫37431‬ ‫37431‬ ‫37431‬ ‫1.3‬ ‫,‪Industry‬‬ ‫‪Electriciy‬‬ ‫58.1‬ ‫‪production‬‬ ‫00021‬ ‫5.23901‬ ‫6989‬ ‫00001‬ ‫9388‬ ‫0008‬ ‫1727‬ ‫1147‬ ‫1366‬ ‫‪VOCs‬‬ ‫0006‬ ‫4435‬ ‫/‬ ‫‪Transportation‬‬ ‫0004‬ ‫5.1253‬ ‫0002‬ ‫2002‬ ‫3002‬ ‫4002‬ ‫5002‬ ‫6002‬ ‫7002‬ ‫ניתן לראות: יחסי הפליטות תחבורה לתעשיה הן לרעת התעשיה ויצור החשמל. התעשייה ויצור‬ ‫החשמל באזור מפרץ חיפה פולטים כמעט פי 2 יותר תרכובות אורגניות נדיפות מאשר סה"כ כל‬ ‫סקטור התחבורה בשנים 7002-4002. אפשר להתייחס לירידה בסקטור התעשיה ויצור החשמל‬ ‫בין השנים 4002 ל-7002 כאל ירידה ממצב גרוע מאוד, למצב גרוע. )מקור: דוח"ות איגוד‬ ‫-2002‬ ‫ערים חיפה לשנים 7002-2002(‬
  • 11. Just for general knowledge…. Does any of you know what weighs 13,000 tons? Answer: 1 bus without passengers is ~13 tons. Imagine 1000 buses – this is the weight of VOC’s spreading in yearly between 2002-2005 on your hometowns. Remember, that some Volatiles show no threshold limit for causation of cancer…
  • 12. 1. Annual averages of Particulate Matter Emission (PM10) concentrations - Comparison between different areas of the bay - years 2006-2007 2007 2006 (PM10) ¯ micrograms/m3 70 59 60 55 53 48 49 50 48 ¯ 50 42 42 39 2006 40 2007 30 P M 10 20 10 0 ' -
  • 13. 2. Validation of Environmental Exposure to Transition Metals From Soil Sampling Manganese/Iron Ratio Anthropogenic = = * ¯
  • 14. 2. Validation of Environmental Exposure to Metals From Soil Sampling Cadmium/P205 Anthropogenic = *
  • 15. 3. Data from The Israeli Environmental Protection Agency – Benzene Concentrations in several educational institutions and schools carried out in 2007-2008, K. Haim, K. Binyamin (Ata), Neve Shannan, Kfar Hasidim 20 18.373 19 18 16.495 16.24 17 16.006 16 15 13.67 ( " ) ¯ ¯ 14 13 " 12 10.485 11 10 9 8 6.519 7 " / 6 ( ) 5 4 3 0.44 2 0.404 0.523 0.559 1 0.382 0.499 0.356 0.318 0 0.162 0.097 0.083 0.153 0.153 0 07- 07- 08 08- = * some air samples showing exceeding levels of carcinogens in schools, residential neighborhoods, etc.
  • 16. 3. Data from The Israeli Environmental Protection Agency – Formaldehyde Concentrations in several educational institutions, and schools carried out in 2007-2008, K. Haim, K. Binyamin (Ata), Kfar Hasidim 6 4.94 ¯ 5 ( " ) ¯ 3.81 4 " 3.328 2.99 3 2.74 2.63 2.829 2.939 2.765 2.862 2.554 2.19 1.891 ( ) 2 1.722 1.516 1.64 1.549 " / 1 0 07- 08 08 = * = * all air samples shown exceed levels of carcinogens allowed. Don’t forget, these are schools, residential neighborhoods, etc.
  • 17. 3. Data from The Israeli Environmental Protection Agency – Dioxins Concentrations in several educational institutions, and schools carried out in 2007-2008, K. Haim (almost 60 phemtograms), K. Binyamin (Ata) – 60-70 phemtograms 0.08 0.07 0.06 ¯ ( " ) 0.05 ¯ 0.04 " 0.03 " / 0.02 0.01 ( ) 0 2007 2007 2008 2008 = * These are considered in the world literature high levels of Dioxins.
  • 18. What does the World Health Organization declare about air pollution and Causality? “Effects for which evidence is sufficient to infer a causal relationship with exposure to air pollution There is now substantial evidence on the adverse effects of air pollution on different pregnancy outcomes and infant health. The evidence shows that air pollution, with concentrations typical of many European cities, increases the risk of death from respiratory causes in the postneonatal period. The evidence also shows a relationship between exposure to ambient air pollutants and adverse effects on the development of lung function. Reversible lung function deficits, chronically reduced lung growth rates and lower lung function levels are associated with exposure to air pollution. Moreover, the evidence shows clearer relationships for particulate matter and traffic-related air pollution (indicated by nitrogen dioxide) than for other pollutants. Based on current knowledge, air pollutants seem to interact with other environmental factors, such as allergens, viruses and diet, that influence the overall impact of air pollutants on children's health. The report concludes that there is a causal relationship between exposure to air pollutants and aggravation of asthma. The evidence is also sufficient to assume a causal link between exposure to particulate matter and increased prevalence and incidence of cough and bronchitis. In particular, such environmental contaminants as certain heavy metals and persistent organic pollutants show significant adverse effects on the development of the nervous system and behaviour in children. Also, there is sufficient evidence of a causal relationship between exposure to lead and neurobehavioral deficits in children, in terms of cognitive impairment." http://www.euro.who.int/HEN/Syntheses/short/20060224_1?PrinterFriendly=1&who
  • 19. There are also good news: We also know that…. Reduction of particulate air pollution levels improves the health and lung functions of children and adults, and saves from mortality. (Laden et al., Pope et al., Avol et al.) This is a scientifically approved fact (see WHO report).
  • 20. Epidemiology at Present… Morbidity ? Are kids in Haifa-bay area any sicker than in other places? Only hints will be given, your answer is needed !
  • 21. General Hospitalizations of Children ages 0-4 presented at precentage above/under the country’s , average (o line) at several cities and districts in years 1998-2002. Source: Lamas
  • 22. ( ) Hospitalizations due to Aggravation of Asthma of Children 0-4 presented at rate/100,000 in several nafot in years 2004-2006. 1800 1600 1400 1200 2004 1000 2005 800 2006 600 400 100,000 200 0 ¯ ¯ - - Source: Ministry of Health, at request
  • 23. This is not the whole picture… Innovative Studies New Air Pollution Cohorts ► Effects on Children’s Cognition through the Olfactory nerve and circulation to brain. ► Effects on Obesity (PCB’s) ► Effects on the risk of developing Asthma in 1st year of life. ► Effects on DNA methylation (BAMSE) - •
  • 24. what awaits the kids in the Haifa–bay area? It’s in our hands to decide! Change Policy-altogether with ?‫שאלות‬ better Research !