emka TECHNOLOGIES provides telemetry systems designed for toxicology & safety pharmacology studies. Complete & smart solutions for researchers performing: - cardiovascular, CNS & pulmonary studies on freely moving, single or group-housed dogs, non-human primates, minipigs, sheep, rabbits, rodents… - strong data analysis, including video recording, glp modules and complete study database.

1. ecg, eeg, emg
respiration
blood pressure
acceleration
skin & core temperature
40°
37°
32°
telemetry for small & large animals
emka TECHNOLOGIES
telemetry.emka.fr

2. telemetry solutions from emka TECHNOLOGIES
software suite for all your needs
iox, data acquisition and real-time analysis
iox acquires, analyzes, displays, controls and stores data generated during an experiment.
»» one file per subject (can append data to same file during successive sessions)
»» subject file contains all information (configuration, calibration, protocol, event
and signal data)
»» real-time monitoring, on line or off line review
»» synchronized video signal stored in same file or in separate file (user option)
»» easily identified subjects with matching numbers on their jacket
ecgAUTO, advanced post-processing analysis
»» fast, reliable and in-depth analysis of ECG
and non-ECG signals
»» for all species, leads, normal and pathological
morphologies
»» pioneering shape-recognition techniques for
powerful analysis
»» synchronized video review
Powerful, fast, reliable ECG analysis
»» beat-by-beat , single, inter and multi lead analysis
»» detects arrythmias, isolated p-waves, abnormal events
»» full range of parameters (intervals, amplitudes, areas, …)
»» predifined or customized subject specific parameter (QTc)
»» extensive data review, edition, export modes
»» automated protocol and batch analysis of successive files
Large choice of analysis modules beyond ECG
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blood pressure or flow, ventricular pressure, action potential
respiration from conductive belts or whole body plethysmograph
EEG/EMG for sleep scoring, epilepsy detection, FFT measurements
NIBP oscillometric blood pressure from cuff
studyDESIGNER, data base tool for your studies
is a high level tool to organize
data recording, analysis, review and archiving on large
toxicology or safety pharmacology studies.
studyDESIGNER
During recording sessions, studyDESIGNER
automatically drives iox and ecgAUTO software to
record and analyze data and send calculated
parameters to its data base.
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defines subject and study structure
defines recording protocols and analysis configurations
reviews and edit analysis results
stores and archive results in database
generate on-demand/custom reports for any combination
of group, phase, subject and all parameters
GLP modules
service & support
Available for all software
emka TECHNOLOGIES provides a full range of support services
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electronic signature
audit trail
user access management
study management
emka TECHNOLOGIES
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pre-installation audits to design optimal system setup, SOP
installation and training
hardware and software validation service
warranty extension, maintenance, and recalibration

3. telemetry solutions from emka TECHNOLOGIES
emkaPACK4G, noninvasive
telemetry for large animals
telemetry monitors the physiology of large
animals noninvasively (no surgery).
emkaPACK4G
It only takes a few minutes to equip the animals with
emkaPACK4G using our custom-designed clothing.
The emkaPACK4G transmits ECG, lung volume, blood
pressure, acceleration and temperature signals.
Each signal type is available as an optional add-on, so you
buy only what you need and can upgrade at any time.
Strong
emkaPACK4G transmitter
Up to 17 signals produced simultaneously
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9 lead ECG
2 respiration belts signals
3 axis + total acceleration, to assess activity and posture
skin or core temperature
blood pressure from 3 methods:
- noninvasive with oscillometric cuff (NIBP)
- semi invasive with vascular access port (VAP)
- minimally invasive with batteryless implant (MIBP)
Smart
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only 1 receiver for 16 animals
only 1 Ethernet cable per receiver
32 to 48 subjects per room, group or single housed
automated software configuration according to selected hardware
remote on/off of individual transmitters and measurement option
warning on lost electrode and low battery, with optional e-mail
emission
emkaPACK4G receiver
transmitter technical characteristics
dimensions
106 x 61 x 25 mm
weight (with batteries)
transmission range
battery life
sampling frequency
170 g
10 m
48 to 72 hours
up to 2kHz/signal
For large animals
»» dogs, primates, pigs, sheep, rabbits
emkaPACK4G typical setup
network
emka TECHNOLOGIES

4. RIP
respiration option
Lung volume measurement via respiratory inductive plethysmography (RIP):
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thoracic and/or abdominal belt(s), fully adjustable and directly connected to main module
respiration flow derived from lung volume
all standard pulmonary parameters
phase shift computation for bronchoconstriction assessment
easy subject specific absolute calibration
NIBP
oscillometric blood pressure module
Blood pressure (NIBP) measurement from noninvasive cuff:
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proven and validated noninvasive oscillometric cuff method
proprietary software for analysis and control
60 to 90% of cycles provide reliable data
automated rejection of unstable cycles
only system to measure NIBP in ambulatory animals
bptVAP vascular access port blood pressure module
temperature module
Blood pressure measurement via vascular access port (VAP):
»» core temperature from implanted probe
»» skin temperature from thermistor
»» easy connection to implanted arterial VAP
»» no transducer drift, easy calibration
»» up to 2 measurement points per animal
receiver
MIBP
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minimally invasvive blood pressure & core body temperature
batteryless reusable implant
pressure tip measurement
core body temperature measured at thermistor tip
no crosstalk, unique frequency for each animal
transmitter
G4KCAPakme
implantMANAGER
inductive
transmitter
emkaPACK4G
inductive
receiver
pressure catheter
»» recalibrated by user prior implantation
implant
carotid
temperature probe
available accessories
»» ECG calibrator
»» ECG signal simulator
»» AA batteries
»» animal jackets & undershirts
»» skin electrodes
»» cuffs, belts

5. rodentPACK,
telemetry for rodents
is a cost-effective telemetry system
to study animals 200g and more, such as rats.
rodentPACK
It acquires EEG, EMG, ECG and temperature, as
well as acceleration and postural information,
suitable for sleep and epilepsy studies, ECG
recordings, heart rate variability assessment, etc.
During recording sessions, the miniature
transmitter plugs into a connector surgically
implanted to the subject’s head.
A single transmitter can be used with any implanted
animal.
Compact, light and powerful
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transmitter has a 22mm diameter and weighs 7g with batteries
120 hours of continuous recording before replacing batteries
5m transmission range
excellent noise-free EEG signal
fast acclimation, up to 40 animals per room without required
shielding
Smart solution for noninvasive ECG
»» transmitter is fitted with miniature ECG cable and
skin electrodes
»» transmitter is housed in pocket of custom design jacket
An ideal alternative
to swivels or implants!
Jacket for noninvasive ECG acquisition
implantable telemetry
In conjonction with Millar, emka TECHNOLOGIES
offers implantable telemetry solutions for animals
200g and over.
Telemeters are recharged by inductive energy
transfer, while still in the animal.
Full range of parameters
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pressure with solid state sensor (Millar)
biopotentials
SNA
temperature
tissue oxygen
easyMATRIX, seamless link from telemetry
emkaTECHNOLOGIES software suite
implants to
easyMATRIX reads
signal from DSI™ implants and only requires
connection to existing receivers and to a computer through USB.
»» records calibrated data in iox2, without the need of OpenART™ or
acquisition card in computer
»» contains its own ambient pressure transducer
Powerful!
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USB connection
easyMATRIX
up to 16 implant receivers and 8 analog inputs connect to a single easyMATRIX
perfect synchronization of all signals from receivers or analog inputs
handles cases with 1, 2 or 4 receivers used for each subject
up to 4 easyMATRIX can be connected to a single computer
telemetry.emka.fr

6. telemetry solutions from emka TECHNOLOGIES
8 compelling reasons to choose our emkaPACK4G telemetry system!
was designed based on more than 10 years of
pioneering experience by emka TECHNOLOGIES in the field of
noninvasive telemetry.
7- 2-way communication between iox2 and emkaPACK4G
There are many strong reasons to use emkaPACK4G large
animal telemetry system.
»» transmitters can remotely be turned on or off, a big
advantage when an animal needs to be removed or
reintroduced in the animal room. Competing product has
been known to become unstable in such situation.
»» In case of low battery, or if an ECG electrode comes off,
or in case of other unwanted events, a specific warning is
received by the software which can optionally be
forwarded by e-mail to on-call staff members.
Here are some of the features that make emkaPACK4G the
gold standard in noninvasive large animal telemetry:
1- All signals are always available when you need them. In
other products, measuring respiration means that you are
restricted to only one ECG chest lead.
2- Only emkaPACK4G lets you adjust the hardware sampling
frequency, for example, ECG at 500Hz, 1000Hz or even 2000Hz.
3- Respiration belts directly connect to the main transmitter
and do not require any adjustments. In other systems you need to
add a separate module, which requires manual gain adjustment and
runs on a battery which is not user replaceable.
4- Respiration belts are made of inexpensive material very
easily cut to the exact required length. Competing product uses
predifined belt lengths with limited possible adjustments.
5- emkaPACK4G is the only system that provides 3 different
methods to measure blood pressure:
»» noninvasive by oscillometric cuff
»» through vascular access port
»» from minimally invasive batteryless implant that also
monitors core body temperature.
6- emkaPACK4G minimally invasive pressure implant uses a
different frequency for each animal which makes crosstalk
impossible in any condition. The competition admits that
crosstalk might occur with group house animals.
provides multiple possibilities to monitor and control the
system:
8
- emkaPACK4G and iox2 software allow to monitor up to
400 signals simultaneously, from anywhere a LAN connection is
available. For example, even if you record 10 signals per subject,
you may still monitor a whole 32 subject study with one single
set-up.
CONTACT US!
for simple to very demanding projects, please call on us
europe
emka TECHNOLOGIES SA
59, bd. Général Martial Valin - 75015 Paris - France
tel: +33 (0)1 40 60 76 00 - fax: +33 (0)1 40 60 65 55
emka@emka.fr
north america
emka TECHNOLOGIES Inc.
307 Annandale Road, suite 203 - Falls Church,VA 22042 - USA
tel: +1 (703)237-9001 - fax: +1 (703)237-9006
emkatech@emkatech.com
china
Beijing GYD Labtech Co Ltd
Rm 935 Laho Studio, No.15-A1 East Jianguo Road
Chaoyang District, Beijing 100024
tel: +86-(0)10-85376382 or +86-(0)13-031151180
or +86-(0)13-01151181
fax:+86-(0)10-58208944
info@bjgyd.com
emka TECHNOLOGIES
All contents Copyright © February 2013 emka TECHNOLOGIES SA. All rights reserved.
Because emka TECHNOLOGIES has a policy of continuous product improvement, we reserve the right to change design and specifications without notice.
emkaPACK4G