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2/3/2010




                       Abdullah Al-Abdali
                            R2 EM




             Outline

Case discussion

Clinical approach to such cases




                                                  1
2/3/2010




82 years old female, presented with:
  Bloody diarrhea with fresh blood
  Abdominal pain
  hematurea




             primary survey



                vital signs




                                             2
2/3/2010




  Sick looking
     P: 110
     BP:85/55
     T:36.9
     sat: 96% on RA
     CRT ??




 0
1 survey
A: patent
B: normal, RR 14, sPO2 96% in RA,
C: P 110, BP 85/55, T 36.9
D: GCS; (14/15), pupils reacting b/l, RBS 7.2
E: NAD




                                                      3
2/3/2010




        Intervention ??




NS boluses
Blood ordered, 6U

Post resuscitation
  P:92
  BP:100/60
  Sat:100% on 100% O2




                                4
2/3/2010




                History

              2nd survey


                  DDx


             Consultation


             Investigation




             2nd survey
H&N ….. Normal
Chest ….. Reduce air entry in lower base
B/L
CVS …… S1+S2, ESM
Abdomen: slightly distended, Soft, tender
all over
PR: fresh blood in the glove, no mass felt
CNS :no obvious neurologic deficit.
ECG: sinus tachycardia




                                                   5
2/3/2010




              History

HTN = not on medication currently
Dx 5 months back as leaking
descending Aortic aneurysm not fit for
any surgical intervention.
B/L pleural effusion under Ix, but she
sign LAMA.




                DDx
aortoenteric fistula
Aortic Aneurysm leakage
Diverticulosis,
Angiodysplasia
Cancer




                                               6
2/3/2010




               Consultations

 General surgery
 Cardio-thoracic surgery
 Cardiology
 Acute medical admission
 Gastroenterology




CBC:                 U/E:
HB: 5
                      Na:140
Hct: 16%
                      K: 4
Plt: 80.4
                      Urea: 13.7
WBC: 62
                      creat:115
ANC:47.1



coagulation:         LFT:
PT:13.8
                      Normal
APTT:34.2



               CT angio




                                         7
2/3/2010




          General surgery

For urgent CT angio.
To be seen by cardio-thoracic




   Cardio-thoracic surgery
To stabilize the patient and to Do CT angio
(chest & abdomen)
To consult cardiologist for assessment
CT angio= Thoracic Aortic aneurism not
increased in size and no leakage from it.
SO, no cardiothoracic interference required
at present, and to be seen by general
medicine for further Management




                                                    8
2/3/2010




             Cardiology

 Bed side ECHO done:
 Normal LV size
 EF:40%
 Normal LA size grade 2 MR
 Mild AS
 Dilated Descending AO
 She is high risk for surgery and GA




Acute medical admission

 d/w Gastro on call, advised admission
 under acute medicine as pt need
 stabilization
 To start Omeprazol and octriotide
 To f/u official CT report




                                               9
2/3/2010




                      CT report

Impression:
   Thoracic aneurysm
   Possibility of subintimal intramural bleed
   Active intraluminal bleed in short
   segment of distal small bowel loop seen
   at left lower abdomen.
   B/L pleural effusion, more in L. side




               Back to surgery
Surgically patient is high risk & needs
optimal localization via selective
mesenteric angio with possible
emboilization.

OGD done
Colonoscopy done
Selective angio done= no abnormal vascularity seen,
tiny bleeding into the lumen of small bowel at they Lt, para-lumbar
area.




                                                                           10
2/3/2010




                 OT
There was blood inside the last 20-30
cm of ileum, there were multiple
ulcers seen with bleeding, Resection
done of about 20-30cm of ileum down
to about 10cm from ileo-caecal valve.




Clinical approach to lower GI bleeding

(LGIB) refers to blood loss of recent
onset originating from a site distal to
the ligament of Treitz.




                                               11
2/3/2010




                         Etiology
Common causes of lower gastrointestinal bleeding
  Anatomical
       Diverticulosis,
   Vascular
       Angiodysplasia
       Ischemic Radiation-induced telangiectasia
   Inflammatory
       Infectious
       Idiopathic inflammatory bowel disease
   Neoplastic
       Polyp
       Carcinoma
   Others
       Hemorrhoid
       Ulcer
       Post biopsy or polypectomy




Diverticulosis — 33 %
Cancers/polyps — 19 %
Colitis/ulcers (including inflammatory bowel disease,
infectious, ischemic, and radiation colitis, vasculitis, and
inflammation of unknown cause)      — 18 %
Unknown — 16 %
Angiodysplasia — 8 %
Miscellaneous (postpolypectomy, aortocolonic
fistula, stercoral ulcer, anastomotic bleeding) — 8 %

Anorectal (hemorrhoids, fissures, and idiopathic rectal
ulcers) — 4 %




                                                                    12
2/3/2010




                    Clinical approach
    Patients should be categorized as:
        low risk
        high risk



Low risk:                     High risk*:
(eg, a young otherwise       including those with:
 healthy patient with        -hemodynamic instability,
self-limited rectal          -serious comorbid diseases,
bleeding that is most        -persistent bleeding,
likely due to an             -the need for multiple blood
internal haemorrhoid)         transfusions
may be evaluated in          -evidence of an acute Abdomen
the outpatient setting.




                     Resuscitation

    All patients with:
        hemodynamic instability (shock,
        orthostatic hypotension),
        evidence of severe bleeding (eg, a
        decrease in hematocrit of at least 6 %,
        or transfusion requirement greater than
        two units of packed red blood cells)
        continuous active bleeding
    should be admitted to an intensive care unit
      for resuscitation and close observation




                                                                  13
2/3/2010




General surgery and gastroenterology
should be involved earlier in
management.

Investigations
  In patients with bleeding suspected to be coming from a
  lower GI source, colonoscopy is suggested (grade 2B).




                                                                 14
2/3/2010




        Take home message:
Visible rectal bleeding occurring in adults warrants an evaluation in
all cases. Patients should be categorized as either low or high risk
for complications based upon their clinical presentation and
hemodynamic status.

Patients with hemodynamic instability, with evidence of severe
bleeding or continuous active bleeding should be admitted to an
intensive care unit for resuscitation and close observation.

follow guidelines that have been issued by the American College of
Gastroenterology and approved by the American gastroenterological
Association and the American Society for Gastrointestinal
Endoscopy for evaluation of the patient with presumed lower
gastrointestinal bleeding.




                  THANK YOU




                                                                             15

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Clinical approach to lower GI bleeding

  • 1. 2/3/2010 Abdullah Al-Abdali R2 EM Outline Case discussion Clinical approach to such cases 1
  • 2. 2/3/2010 82 years old female, presented with: Bloody diarrhea with fresh blood Abdominal pain hematurea primary survey vital signs 2
  • 3. 2/3/2010 Sick looking P: 110 BP:85/55 T:36.9 sat: 96% on RA CRT ?? 0 1 survey A: patent B: normal, RR 14, sPO2 96% in RA, C: P 110, BP 85/55, T 36.9 D: GCS; (14/15), pupils reacting b/l, RBS 7.2 E: NAD 3
  • 4. 2/3/2010 Intervention ?? NS boluses Blood ordered, 6U Post resuscitation P:92 BP:100/60 Sat:100% on 100% O2 4
  • 5. 2/3/2010 History 2nd survey DDx Consultation Investigation 2nd survey H&N ….. Normal Chest ….. Reduce air entry in lower base B/L CVS …… S1+S2, ESM Abdomen: slightly distended, Soft, tender all over PR: fresh blood in the glove, no mass felt CNS :no obvious neurologic deficit. ECG: sinus tachycardia 5
  • 6. 2/3/2010 History HTN = not on medication currently Dx 5 months back as leaking descending Aortic aneurysm not fit for any surgical intervention. B/L pleural effusion under Ix, but she sign LAMA. DDx aortoenteric fistula Aortic Aneurysm leakage Diverticulosis, Angiodysplasia Cancer 6
  • 7. 2/3/2010 Consultations General surgery Cardio-thoracic surgery Cardiology Acute medical admission Gastroenterology CBC: U/E: HB: 5 Na:140 Hct: 16% K: 4 Plt: 80.4 Urea: 13.7 WBC: 62 creat:115 ANC:47.1 coagulation: LFT: PT:13.8 Normal APTT:34.2 CT angio 7
  • 8. 2/3/2010 General surgery For urgent CT angio. To be seen by cardio-thoracic Cardio-thoracic surgery To stabilize the patient and to Do CT angio (chest & abdomen) To consult cardiologist for assessment CT angio= Thoracic Aortic aneurism not increased in size and no leakage from it. SO, no cardiothoracic interference required at present, and to be seen by general medicine for further Management 8
  • 9. 2/3/2010 Cardiology Bed side ECHO done: Normal LV size EF:40% Normal LA size grade 2 MR Mild AS Dilated Descending AO She is high risk for surgery and GA Acute medical admission d/w Gastro on call, advised admission under acute medicine as pt need stabilization To start Omeprazol and octriotide To f/u official CT report 9
  • 10. 2/3/2010 CT report Impression: Thoracic aneurysm Possibility of subintimal intramural bleed Active intraluminal bleed in short segment of distal small bowel loop seen at left lower abdomen. B/L pleural effusion, more in L. side Back to surgery Surgically patient is high risk & needs optimal localization via selective mesenteric angio with possible emboilization. OGD done Colonoscopy done Selective angio done= no abnormal vascularity seen, tiny bleeding into the lumen of small bowel at they Lt, para-lumbar area. 10
  • 11. 2/3/2010 OT There was blood inside the last 20-30 cm of ileum, there were multiple ulcers seen with bleeding, Resection done of about 20-30cm of ileum down to about 10cm from ileo-caecal valve. Clinical approach to lower GI bleeding (LGIB) refers to blood loss of recent onset originating from a site distal to the ligament of Treitz. 11
  • 12. 2/3/2010 Etiology Common causes of lower gastrointestinal bleeding Anatomical Diverticulosis, Vascular Angiodysplasia Ischemic Radiation-induced telangiectasia Inflammatory Infectious Idiopathic inflammatory bowel disease Neoplastic Polyp Carcinoma Others Hemorrhoid Ulcer Post biopsy or polypectomy Diverticulosis — 33 % Cancers/polyps — 19 % Colitis/ulcers (including inflammatory bowel disease, infectious, ischemic, and radiation colitis, vasculitis, and inflammation of unknown cause) — 18 % Unknown — 16 % Angiodysplasia — 8 % Miscellaneous (postpolypectomy, aortocolonic fistula, stercoral ulcer, anastomotic bleeding) — 8 % Anorectal (hemorrhoids, fissures, and idiopathic rectal ulcers) — 4 % 12
  • 13. 2/3/2010 Clinical approach Patients should be categorized as: low risk high risk Low risk: High risk*: (eg, a young otherwise including those with: healthy patient with -hemodynamic instability, self-limited rectal -serious comorbid diseases, bleeding that is most -persistent bleeding, likely due to an -the need for multiple blood internal haemorrhoid) transfusions may be evaluated in -evidence of an acute Abdomen the outpatient setting. Resuscitation All patients with: hemodynamic instability (shock, orthostatic hypotension), evidence of severe bleeding (eg, a decrease in hematocrit of at least 6 %, or transfusion requirement greater than two units of packed red blood cells) continuous active bleeding should be admitted to an intensive care unit for resuscitation and close observation 13
  • 14. 2/3/2010 General surgery and gastroenterology should be involved earlier in management. Investigations In patients with bleeding suspected to be coming from a lower GI source, colonoscopy is suggested (grade 2B). 14
  • 15. 2/3/2010 Take home message: Visible rectal bleeding occurring in adults warrants an evaluation in all cases. Patients should be categorized as either low or high risk for complications based upon their clinical presentation and hemodynamic status. Patients with hemodynamic instability, with evidence of severe bleeding or continuous active bleeding should be admitted to an intensive care unit for resuscitation and close observation. follow guidelines that have been issued by the American College of Gastroenterology and approved by the American gastroenterological Association and the American Society for Gastrointestinal Endoscopy for evaluation of the patient with presumed lower gastrointestinal bleeding. THANK YOU 15