1. Mic
a
Mica: An integrated web platform to
support epidemiological studies
Etienne Morency (emorency@p3g.org)

2. Mic
 What is Mica ? a
 Mica infrastructure (Maelstrom repository)
 Step 1: Mica Catalogues
 Step 2: Mica Variables
 Step 3: Processing, Integration and Dissemination
 Conclusion
2 4/26/2012

3. Software Infrastructure Mic
 Mealstrom-Research

a
Web portal to document studies that are using our harmonization
tools
 Operational IT infrastructure that supports management of individual
harmonization projects
 Integrated – Series of interrelated software (ONYX, OPAL, MICA,
DataSHIELD and DataSHaPER). Solid “communication routes” with other
resources (PhenX, Molgenis, DDI):
 Comprehensive – Support all steps of the harmonization process from
study description to database federation and statistical analysis
 Open source – Based on state-of-the-art and widely used open source
frameworks, highly customizable and secure, freely available.
 Toolkit to build websites for a study or a consortium
 Easy to install, to manage and extremely customizable (based on
Drupal and PHP)
3 4/26/2012

4. Architecture Mic
a
 3 architectures that links to the central repository (all
share core information)
Network
Hosted
Maelstrom-
Research
Independent
4 4/26/2012

6. Mic
a
1. Identifying and cataloguing
participating studies

9. Study Catalogue Mic
a
9 4/26/2012

11. Mic
a
2. Identifying variables for
harmonization

14. Mic
a
3. Data processing, integration and
dissemination

18. Integration with Opal Mic
a
Kora-gen UK Biobank LifeGene
1800 50,000 50,000
participants participants participants
Harmonized Harmonized
Dataset Dataset
Mica
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20. Conclusion Mic
 Other Features a
 Role-based access control (files, fields, content types)
 Dissemination of Publications/Events/Projects/News
 And many other extensions (calendar, publication
workflow…)
 Updates
 Ongoing development
 Catalogues (Questionnaires, Access, Biosamples
Physical Measures) / Follow-up
 Continue the integration with existing tools
 Implement the central repository: Maelstrom-Research
 Translations support
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