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Online KOLs: Can You Choose to Ignore Them?


Debjani Deb
Managing Partner




Friday, July 01, 2011                          Listen. Learn. EmPower
                                                                1
Pharma stakeholders are online today


                                                66%                                 35%                    60%


                  63%



    of online adults search                  look up a specific               Seek Alternative     Search for “someone
    for health information                   disease or problem               treatments           like me” experience



               6 out of 10

                                                   66%                                50%                   21%



                                             of Pharma companies                 of online Physicians   of physicians use
     Doctors are online                      use social media                    refer to Wikipedia     Social Media to
                                                                                                        connect to KOLs

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1
    Points f i fl
    P i t of influence are developing
                            d    l i
    amid all the online chatter …


2
    …leading to impact on decisions
    made….


3
    ...to the extent which is beyond
    the control of Pharma companies
Who is an Online Influencer: The many possible forms


       Patients                                Caregivers                  Advocacy Grps.         Physicians




     Amanda Lyn                               Deanna Runyan-                Tuberous Sclerosis   KevinMD Blog :
      Escamilla:                                     Wall:                      Association:          Leading
     A 29 year old                           A Caregiver, whose                A UK charity to     destination for
    patient of TSC                            son suffers from              promote awareness,
                                                                                     awareness      provocative
     who regularly                           TSC, makes use of                seek causes and        physician
    shares her life                          multiple channels to               best possible     commentary on
    experiences on                            tell her story and               management of     breaking medical
      Facebook                                 motivate others                      TSC                news


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The debate today: Influence vs. popularity




                                             Popularity




                                                                         Influence


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Companies currently are focused on tools, methodology and
             ranking


                                                                      Tools for aggregating
                                                                      influencer information
                                                                      across channels




                                                                      Methodology and
                                                                      processes to identify
                                                                      and rank influencers




                                                                      Profiling and
                                                                      achieving influencer
                                                                      data (tool or manual)


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Limitations of prevailing perspectives on influencer tracking




                                                                                           Does not take into account
                                                                                           influencer applications

                                                                        Ignores End
     Non customized                                                     Applications

                                             Cookie
                                                                                         Does not effectively
                                             Cutters                                     segment influencers
                                                       Limitations
 Process centric –
 P          ti
 not need centric                                                                      Comprehensive metrics
                                                                                       measuring impact not defined
                                                                      Ignores
                                                                      Impact
                                                                                       Mechanism to measure key
                                                                                       metrics not in place




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IN NEXT




                          MINUTES WE WILL DISCUSS
                                          DISCUSS…
                                    APPLICATIONS OF ONLINE INFLUENCERS

                                    USE CASES

                                    BEST PRACTICES AND CONCLUSIONS



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Online influencers can be segmented


                                                        Stakeholder type
                                                 Physician, patient, caregiver etc.


                                                                    1


   Influence Depth                                                                               Activity level
    Stage of disease                         5                                            2     Active vs. passive
 lifecycle influenced                                                                               influence

                                                            Segments



        Influence Area                                                                    Engagement channels
       Therapeutic area                            4                                  3          Channels where
     or b
        brands of influence
             d f i fl                                                                      iinfluence iis prominent
                                                                                              fl              i   t


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Application areas across influencer segments


                                                           Adherence
                                                          management


                                        Influencing
                                         decisions
                                                          4
                                                                                      Crisis
                                       across patient                               management
                                                                                        g
                                          pathway
      Clinical trial                                       HCP advice                            Physician drug
                                         2                corroboration             7              advocacy
      participation
     and spreading
         results
              lt
                                             Regulatory
       1                                                  5                           Advisory    9
                                             Advocacy
                                                                                     committee
                                                                                       work

                                             3                                      8
                                                            Marketing


                                                           6

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Use Case 1: Clinical trial participation and spreading results



                                                                            Blogs
                                                     Independent
                                                     I d    d t
       Avalon Love, a                                Communities
      caregiver having                                                                         Mass Social
        thousands of                                                                  Blogs      Media

      online followers
              followers,
                                                                                                (Facebook,
                                             Blogs                                               You Tube
                                                                                                     Tube,

         is an active                                        Discussion                         LinkedIn…)
                                                               Groups
     proponent of drug
          trials for a
                                                                                Community
     Multiple Sclerosis                                                           Portal
       drug as she is
       happy with her
                                                                                                    Advocacy          Local
                                                Influencer                                           Groups            User

                                                    Site
                                                                                                                      Groups
        son s
        son’s results.                                                                 Other
                                                                                       Oth
                                                                                       KOLs
                                                                                                             Regulators




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Use Case 2: Influencing decisions across patient pathway




                                                                       101,100                         357,100
           Pharma                                                      Visitors                        Visitors

      companies today
      track influencers                      MDJunction is an active
                                             center for Online Support
                                                                                    Featuring over 500
        who influence                        Groups. Acromegaly patient
                                             G        A         l   ti t
                                                                                    communities, including
                                                                                                  ,       g
       decision nodes
                                                                                    detailed information on
                                             journey is extensively
                                                                                    treatments and symptoms on
         across the                          discussed by support groups
                                                                                    Acromegaly
                                             in this website
      patient pathway.

       This helps them
        enhance their
      advocacy across
      disease life cycle                           Pre
                                                                      Diagnosis   Treatment      Lifestyle
                                                Diagnosis




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Use Case 3: Regulatory advocacy




                                                TS Alliance was able to
        During an FDA                           generate more than 390
       Advisory Panel                         Congressional visits to urge
          hearing, TS
                                                                              “
                                             increased Federal funding for
                                                                                  Research on TSC is
            Alliance                                TSC research .
                                                                                  having significant impact
         constituents                                                             on our understanding of
         advocate for                                                             epilepsy, autism, spectrum
          approval of                                                             disorder, cancer and
           vigabatrin                                                             diabetes,
                                                                                  diabetes and the TSC
                                                                                  program is critical to
      (Sabril), which is

                                                                                                    ”
                                                                                  ongoing progress.
          eventually
                                                                                  Sherrod Brown
       approved by the                                                            United St t
                                                                                  U it d States Senator
                                                                                                S   t
         FDA to treat
      infantile spasms




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Use Case 4: Adherence management



                                             Earlier Method                  Advocated Method
         Dr. E
         D Eugene
      Woltering’s blog
        educates on
         delivery of
                 y
      Sandostatin by
           infusion
     pump, rather than
       by injection in
       office setting.                        Benefits:
     This resulted in                          • Better symptom control
                                               • Allows use of less medication
                                                                    medication.
   higher efficacy and
                                               • Results lower rate of tumor growth.
    better treatment.




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Use Case 5: HCP advice corroboration




       Lauren’s blog                                                            Reading this blog has
                                                                                R di thi bl h
     “Living with MS”                                                           calmed my apprehensions
                                                                                and validated my decision
       discusses all                                                            to have my first Tysabri
         aspects of                                                             infusion tomorrow.
                                                                                i f i t
                                             Consulting
     Multiple Sclerosis                                             Chance to    - Patient

                                             1
        and various                                                 talk
        treatments.
                                                                     2
     Patients consider
                                                   Treatment
        her opinion                                options                      At disease.com , we are
       equivalent to
                                                   3
                                                                                inspired by your stories
     their Neurologist.                                                         and would like to join you
                                                                                in fighting this cause.
                                                                                - Advocacy




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Use Case 6: Marketing



                                             Results:
          In order to
       market Prilosec                                                                      1,225,000
      OTC, a heartburn                                                                    unique visitors
      medication, P&G                                                                        on blogg
        assembled a                                                          75,789
      database of 200                                                         unique
      influential blogs,                                                    visitors to
      message b  boards
                      d                                                     promotion
      and Web sites in                                                         site
                                                25,275
         the area of                            unique
        p
        parenting for
                 g                            sweepstakes
           targeted                             entries
          marketing




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Use Case 7: Crisis management




                                             Recall Reach:                                        Virality:
      A few renowned
      experts carried
     Pharma Co’s view                                                              1141
                                                                                                        82%
     on a recent drug
       recall in their                             25
           blogs.                            Traditional Media                  Social Media


       This h l d the
       Thi helped th
                                             Tonality Earlier:                             Tonality Later:
        Pharma Co to
       contain damage
         to its brand                                                         Negative                        Negative

          equity to a                                                         Neutral                         Neutral
           minimal.




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Use Case 8: Advisory committee work


                                                                                      Better Relationship
                                                                                      with Scientific
                                                                                      Communities
  Pharma companies
  rank KOLs on reach



                                             Message Congruence
    and congruence.
                                                                                                      Better Relationship
      High ranking                                                                                    with Patient
    opinion leaders                                                                                   Communities
    often represent                                               Passive
                                                                   ass e
   them on advisory                                               Influencers
  committees as they
    are popular with
  both scientific and
         patient
      communities
                                                                                            Reach



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Use Case 9: Physician drug advocacy


                                                   What Patients Felt                          What Physicians Said

                                             70                                           70

     Many patients                           60                                           60


   wanted to switch
                                             50                                           50
                                             40                                           40
        to more                              30                                           30

      economical                             20                                           20

   alternatives for a                        10                                           10

  particular MS drug.
                                              0                                            0
                                                  Price Theme 2 Theme 3 Theme 4 Theme 5        Theme 5 Theme 4 Theme 3 Theme 2 Efficacy



     However, this
     negativity was                                                                                               Loyalists
   contained as most
       Physicians                                  Switchers
    consider Tysabri
    very efficacious.

                                                                                                               Prospects
                                                                                                               P      t


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Identify the goal of using the influencer

             Identify Influencers
                                  By
             By Category                         By Brands         By Issues
                             Applications




               Reach
                           Filter                         Profile
               Focus                                              Engagement
  BEST                                           Influence Area
PRACTICES
                                                                   Channels
             Engagement
                                                  Congruence      Influence Map




            Measure
            Impact
                          Crisis     Advocacyy          Sales      Reputation
                                                                     p
                       Containment    Impact           Impact       Impact
In Conclusion

         Online Influencers are growing in influence and are active as we speak


         Pharma cannot be reactive to this group. That is where we are today

         The landscape is easily understandable and usable to your advantage




             Social media is an engagement medium. That very
              definition lends itself to be a medium of influence
                and impact on a peer to peer basis. Pharma
              marketing can use this powerfully by paying due
                   atte t o
                   attention to influencers in t s medium.
                                    ue ce s this ed u

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www.empowerresearch.com




                          Retail/CPG         Advertising   Communications/           High Tech/   Pharmaceuticals     Financial 
                                                           Public Relations          Telecom      Health Care         Services




  Corporate Headquarters

  Debjani Deb
  Managing Partner
  EmPower Research LLC
  404 E. 79th St.
  Suite 16E
  New York, NY 10075

  Tel : +1 650 559 5942
  Fax : +1 646 472 5806




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Online KOLs: Can you choose to ignore them? (2nd Digital Pharma West,2011)

  • 1. www.empowerresearch.com Online KOLs: Can You Choose to Ignore Them? Debjani Deb Managing Partner Friday, July 01, 2011 Listen. Learn. EmPower 1
  • 2. Pharma stakeholders are online today 66% 35% 60% 63% of online adults search look up a specific Seek Alternative Search for “someone for health information disease or problem treatments like me” experience 6 out of 10 66% 50% 21% of Pharma companies of online Physicians of physicians use Doctors are online use social media refer to Wikipedia Social Media to connect to KOLs EmPower Research LLC. All Rights Reserved. Listen. Learn. EmPower 2
  • 3. 1 Points f i fl P i t of influence are developing d l i amid all the online chatter … 2 …leading to impact on decisions made…. 3 ...to the extent which is beyond the control of Pharma companies
  • 4. Who is an Online Influencer: The many possible forms Patients Caregivers Advocacy Grps. Physicians Amanda Lyn Deanna Runyan- Tuberous Sclerosis KevinMD Blog : Escamilla: Wall: Association: Leading A 29 year old A Caregiver, whose A UK charity to destination for patient of TSC son suffers from promote awareness, awareness provocative who regularly TSC, makes use of seek causes and physician shares her life multiple channels to best possible commentary on experiences on tell her story and management of breaking medical Facebook motivate others TSC news EmPower Research LLC. All Rights Reserved. Listen. Learn. EmPower 4
  • 5. The debate today: Influence vs. popularity Popularity Influence EmPower Research LLC. All Rights Reserved. Listen. Learn. EmPower 5
  • 6. Companies currently are focused on tools, methodology and ranking Tools for aggregating influencer information across channels Methodology and processes to identify and rank influencers Profiling and achieving influencer data (tool or manual) EmPower Research LLC. All Rights Reserved. Listen. Learn. EmPower 6
  • 7. Limitations of prevailing perspectives on influencer tracking Does not take into account influencer applications Ignores End Non customized Applications Cookie Does not effectively Cutters segment influencers Limitations Process centric – P ti not need centric Comprehensive metrics measuring impact not defined Ignores Impact Mechanism to measure key metrics not in place EmPower Research LLC. All Rights Reserved. Listen. Learn. EmPower 7
  • 8. IN NEXT MINUTES WE WILL DISCUSS DISCUSS… APPLICATIONS OF ONLINE INFLUENCERS USE CASES BEST PRACTICES AND CONCLUSIONS EmPower Research LLC. All Rights Reserved. Listen. Learn. EmPower 8
  • 9. Online influencers can be segmented Stakeholder type Physician, patient, caregiver etc. 1 Influence Depth Activity level Stage of disease 5 2 Active vs. passive lifecycle influenced influence Segments Influence Area Engagement channels Therapeutic area 4 3 Channels where or b brands of influence d f i fl iinfluence iis prominent fl i t EmPower Research LLC. All Rights Reserved. Listen. Learn. EmPower 9
  • 10. Application areas across influencer segments Adherence management Influencing decisions 4 Crisis across patient management g pathway Clinical trial HCP advice Physician drug 2 corroboration 7 advocacy participation and spreading results lt Regulatory 1 5 Advisory 9 Advocacy committee work 3 8 Marketing 6 EmPower Research LLC. All Rights Reserved. Listen. Learn. EmPower 10
  • 11. Use Case 1: Clinical trial participation and spreading results Blogs Independent I d d t Avalon Love, a Communities caregiver having Mass Social thousands of Blogs Media online followers followers, (Facebook, Blogs You Tube Tube, is an active Discussion LinkedIn…) Groups proponent of drug trials for a Community Multiple Sclerosis Portal drug as she is happy with her Advocacy Local Influencer Groups User Site Groups son s son’s results. Other Oth KOLs Regulators EmPower Research LLC. All Rights Reserved. Listen. Learn. EmPower 11
  • 12. Use Case 2: Influencing decisions across patient pathway 101,100 357,100 Pharma Visitors Visitors companies today track influencers MDJunction is an active center for Online Support Featuring over 500 who influence Groups. Acromegaly patient G A l ti t communities, including , g decision nodes detailed information on journey is extensively treatments and symptoms on across the discussed by support groups Acromegaly in this website patient pathway. This helps them enhance their advocacy across disease life cycle Pre Diagnosis Treatment Lifestyle Diagnosis EmPower Research LLC. All Rights Reserved. Listen. Learn. EmPower 12
  • 13. Use Case 3: Regulatory advocacy TS Alliance was able to During an FDA generate more than 390 Advisory Panel Congressional visits to urge hearing, TS “ increased Federal funding for Research on TSC is Alliance TSC research . having significant impact constituents on our understanding of advocate for epilepsy, autism, spectrum approval of disorder, cancer and vigabatrin diabetes, diabetes and the TSC program is critical to (Sabril), which is ” ongoing progress. eventually Sherrod Brown approved by the United St t U it d States Senator S t FDA to treat infantile spasms EmPower Research LLC. All Rights Reserved. Listen. Learn. EmPower 13
  • 14. Use Case 4: Adherence management Earlier Method Advocated Method Dr. E D Eugene Woltering’s blog educates on delivery of y Sandostatin by infusion pump, rather than by injection in office setting. Benefits: This resulted in • Better symptom control • Allows use of less medication medication. higher efficacy and • Results lower rate of tumor growth. better treatment. EmPower Research LLC. All Rights Reserved. Listen. Learn. EmPower 14
  • 15. Use Case 5: HCP advice corroboration Lauren’s blog Reading this blog has R di thi bl h “Living with MS” calmed my apprehensions and validated my decision discusses all to have my first Tysabri aspects of infusion tomorrow. i f i t Consulting Multiple Sclerosis Chance to - Patient 1 and various talk treatments. 2 Patients consider Treatment her opinion options At disease.com , we are equivalent to 3 inspired by your stories their Neurologist. and would like to join you in fighting this cause. - Advocacy EmPower Research LLC. All Rights Reserved. Listen. Learn. EmPower 15
  • 16. Use Case 6: Marketing Results: In order to market Prilosec 1,225,000 OTC, a heartburn unique visitors medication, P&G on blogg assembled a 75,789 database of 200 unique influential blogs, visitors to message b boards d promotion and Web sites in site 25,275 the area of unique p parenting for g sweepstakes targeted entries marketing EmPower Research LLC. All Rights Reserved. Listen. Learn. EmPower 16
  • 17. Use Case 7: Crisis management Recall Reach: Virality: A few renowned experts carried Pharma Co’s view 1141 82% on a recent drug recall in their 25 blogs. Traditional Media Social Media This h l d the Thi helped th Tonality Earlier: Tonality Later: Pharma Co to contain damage to its brand Negative Negative equity to a Neutral Neutral minimal. EmPower Research LLC. All Rights Reserved. Listen. Learn. EmPower 17
  • 18. Use Case 8: Advisory committee work Better Relationship with Scientific Communities Pharma companies rank KOLs on reach Message Congruence and congruence. Better Relationship High ranking with Patient opinion leaders Communities often represent Passive ass e them on advisory Influencers committees as they are popular with both scientific and patient communities Reach EmPower Research LLC. All Rights Reserved. Listen. Learn. EmPower 18
  • 19. Use Case 9: Physician drug advocacy What Patients Felt What Physicians Said 70 70 Many patients 60 60 wanted to switch 50 50 40 40 to more 30 30 economical 20 20 alternatives for a 10 10 particular MS drug. 0 0 Price Theme 2 Theme 3 Theme 4 Theme 5 Theme 5 Theme 4 Theme 3 Theme 2 Efficacy However, this negativity was Loyalists contained as most Physicians Switchers consider Tysabri very efficacious. Prospects P t EmPower Research LLC. All Rights Reserved. Listen. Learn. EmPower 19
  • 20. Identify the goal of using the influencer Identify Influencers By By Category By Brands By Issues Applications Reach Filter Profile Focus Engagement BEST Influence Area PRACTICES Channels Engagement Congruence Influence Map Measure Impact Crisis Advocacyy Sales Reputation p Containment Impact Impact Impact
  • 21. In Conclusion Online Influencers are growing in influence and are active as we speak Pharma cannot be reactive to this group. That is where we are today The landscape is easily understandable and usable to your advantage Social media is an engagement medium. That very definition lends itself to be a medium of influence and impact on a peer to peer basis. Pharma marketing can use this powerfully by paying due atte t o attention to influencers in t s medium. ue ce s this ed u EmPower Research LLC. All Rights Reserved. Listen. Learn. EmPower 21
  • 22. www.empowerresearch.com Retail/CPG Advertising Communications/ High Tech/ Pharmaceuticals Financial  Public Relations Telecom Health Care Services Corporate Headquarters Debjani Deb Managing Partner EmPower Research LLC 404 E. 79th St. Suite 16E New York, NY 10075 Tel : +1 650 559 5942 Fax : +1 646 472 5806 EmPower Research LLC. All Rights Reserved. Listen. Learn. EmPower Listen. Learn. EmPower 22 22