Chap 10 enzyme

ENZYME ,[object Object],[object Object],[object Object]

Definition ,[object Object],[object Object]

E A with enzyme Figure 5.5B Reactants Products E A without enzyme Net change in energy

Important Terms… ,[object Object],[object Object],[object Object]

Cont… ,[object Object],[object Object],Figure 8.16 Substate Active site Enzyme (a)

Cont… ,[object Object],[object Object],[object Object],[object Object]

Enzyme Inhibitors ,[object Object],[object Object],(b) Competitive inhibition A competitive inhibitor mimics the substrate, competing for the active site. Competitive inhibitor A substrate can bind normally to the active site of an enzyme. Substrate Active site Enzyme (a) Normal binding

Cont… ,[object Object],[object Object],A noncompetitive inhibitor binds to the enzyme away from the active site, altering the conformation of the enzyme so that its active site no longer functions. Noncompetitive inhibitor (c) Noncompetitive inhibition

Competitive and noncompetitive inhibition

Types of enzymes ,[object Object],[object Object],[object Object],[object Object],[object Object]

[object Object],Enzyme (sucrase) Active site 1 2 3 Substrate (sucrose) Enzyme available with empty active site Substrate binds to enzyme with induced fit Substrate is converted to products 4 Products are released Glucose Fructose ,[object Object],Figure 5.6

Characteristics ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Cont… ,[object Object],[object Object],[object Object],[object Object],[object Object]

Mechanisms of Enzymes ,[object Object],[object Object],[object Object],[object Object]

Lock-and-key hypothesis ,[object Object],[object Object],[object Object],[object Object],[object Object]

Induced-fit hypothesis ,[object Object],[object Object],[object Object],[object Object]

factors ,[object Object],[object Object]

The effect of Temperature ,[object Object],[object Object],[object Object],[object Object]

The effect of pH ,[object Object],[object Object],[object Object],[object Object]

Cont… ,[object Object],[object Object],[object Object]

The effect of Enzyme Concentration ,[object Object]

The effect of Substrate Concentration ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

classification ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Chap 10 enzyme

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Chap 10 enzyme