2. FOOT REPAIR ENZYMATIC PEEL OFF
• The feet are:
constantly called upon
too often neglected.
8 out of 10 people suffer from their feet.
• The skin of the feet is:
Poorly moisturized
Irritated.
On the sites of pressure:
itchiness
fissures
cracks.
3. FOOT REPAIR ENZYMATIC PEEL OFF
IN THE EPIDERMIS: SPECIFIC PROTEOLYTIC ENZYMES
→ Responsible for the complex process of desquamation.
When the balance is upset
→ the degeneration of the epidermis is activated,
⇒ the skin becomes:
thicker,
dryer,
irritated.
Several factors are involved
Endogenous: deficient enzymes
Exogenous: environment, repeated mechanical stress, poor hygiene.
4. FOOT REPAIR ENZYMATIC PEEL OFF
Recent research in the field of cell biology and
biochemistry has given rise to PEDICARE, a
comprehensive and specific foot treatment.
Our research department selected PROZYMEX
HBT LS 9142: a powerful complex of stabilized
enzymes, obtained by biosynthesis.
PROZYMEX HBT LS 9142, very rich in proteases:
→ Exerts a strong keratolytic action:
PEEL OFF ACTION
→ Accelerates cell renewal
→ Suitable for the epidermal pH.
PROZYMEX HBT LS 9142 boosts the effect of the
endogenous epidermal enzymes.
5. EPIDERMIS
• The skin is the largest organ
with three main layers:
EPIDERMIS
Epidermis
Dermis
Hypodermis.
• Thickness of the epidermis:
DERMIS
0.1 mm
EXCEPT on the soles of the
feet and the palms of the
hands:
→ The thickness may reach HYPODERMIS
1mm or more.
6. REMINDER OF THE EPIDERMIS STRUCTURE
The epidermis is composed of several
layers. Horny layer
• BASAL LAYER:
Continuous renewal of epidermal cells. Clear layer
A single row of cells able to divide
themselves frequently.
Granular
layer
→ Half of the cells begins the maturation
process.
Spinous layer
→ The other half stays in the basal layer
and divides over and over.
Basal layer
• SPINOUS LAYER
• GRANULAR LAYER: the cells produce Basement Membrane
keratin.
• CLEAR LAYER, present only in thick skin → feet and hands: reduces the
friction forces between the granular and stratum corneum layers.
7. REMINDER OF THE EPIDERMIS STRUCTURE
• HORNY LAYER:
→ The cells migrate from the
basal layer to the superficial layer
or stratum corneum → they
differentiate: corneocytes.
Corneocytes:
“bricks and mortar” type structure
are held together by corneosomes
and the intercellular cement.
• Components of the
intercellular cement:
→ Proteins
→ Lipids.
8. DESQUAMATION
THE SKIN’S NATURAL EXFOLIATION PROCESS
• Epidermal desquamation:
From the birth of a keratinocyte in the basal layer until it is exfoliated from
the epidermal surface→ 4 weeks.
• But the migration process can also take:
→ 75 days depending on the age and skin conditions.
• Over time, the intercellular
cement becomes denser.
Exfoliation becomes more
difficult.
Cells pile up in the stratum
corneum.
9. DESQUAMATION
THE SKIN’S NATURAL EXFOLIATION PROCESS
• EPIDERMAL DESQUAMATION:
Induced by different enzymes:
PROTEASES or proteolytic
enzymes produced by the
stratum corneum
They break the peptide
bonds of the proteins.
Remove corneocytes on the
surface of the epidermis by
hydrolyzing the peptide
bonds between them.
The hydrolysis parts
corneocytes from one another.
10. DESQUAMATION
THE SKIN’S NATURAL EXFOLIATION PROCESS
• IMPORTANCE OF EXFOLIATION
Stimulates the cell renewal
Improves the skin appearance and
texture.
• DISORDERS OF EXFOLIATION PROCESS
→ Environmental factors
→ Hormonal influences
→ Vitamin deficiency
→ Enzyme deficiency.
• CONSEQUENCES
Degeneration of the epidermis
the skin becomes:
Thicker
Dryer
Irritated.
11. DEHYDRATION / HYPERKERATINIZATION
CRACKS AND CALLUSES
• Various factors contribute to dry feet:
Exposure to high temperatures
Repeated baths or showers.
• Different skin disorders:
Eczema
Diabetes
Fungal infections.
• Repeated mechanical stress:
→ the stratum corneum thickens CALLUSES.
• SHORT-TERM EFFECT, a dehydrated skin:
→ Loses its flexibility
→ CRACKS.
• LONG-TERM EFFECT, the skin CRACKS deeply:
→ The cracks are forming CALLUSES.
12. VASCULAR SYSTEM / EDEMA
SWOLLEN FEET
• Arteries carry the blood rich in oxygen from
the heart to the tissues.
• Veins carry oxygen-depleted blood from the
lower limbs to the heart.
• A system of VALVES prevents the blood
from flowing back down.
• Any malfunctioning of the system causes a
VENOUS INSUFFICIENCY:
Heavy legs
Swelling legs
Discomfort
Pain
Edema
Varicose veins.
• Heat increases the venous insufficiency.
13. FOOT FUNGAL INFECTION
• INFECTION CAUSED BY:
Dermatophytes, which feed on keratin
Yeast like candida.
• CAUSES of the contamination :
Humid environment
Shoes promoting perspiration.
• Foot fungal infection is characterized by:
Scaling (desquamation)
Itching
Fissuring of the infected area.
• Nail fungal infection: Onychomycosis.
14. PROZYMEX HBT LS 9142
• PROZYMEX, synergistic complex of highly stabilized proteases.
SUBTILISIN, bacterial protease
PROTEASE derived from biotechnology
→ Accelerates the natural exfoliation of the epidermal upper layers.
→ Promotes cell renewal in the epidermis
• PROZYMEX
Compensates for the epidermal enzyme deficiency.
15. PROZYMEX HBT LS 9142
IN VITRO TEST: KERATOLYTIC ACTIVITY
• From human epidermis: extraction of the keratin + addition of different
PROZIMEX concentrations and then keratin dosage amount.
KERATIN DECREASED BY 60% IN 3 HOURS
16. PROZYMEX HBT LS 9142
EX VIVO TEST: KERATOLYTIC EFFECT
• On human skin: deterioration of the keratin proteins into amino acids.
• The deeper the color the more free amino acids there are the more
significant the desquamation effect is.
PROZYMEX
INCREASES
EPIDERMAL
DESQUAMATION
17. UREA
• PROPERTIES:
HYGROSCOPIC
Its binds water on the surface to the other layers of the epidermis.
Maintains good hydration of the epidermis.
Effective and long-lasting moisturizing effect.
KERATOLYTIC
Eases scaling of the epidermal corneocytes.
SOOTHING:
Itching sensations of the dry skins.
18. 70% GLYCOLIC ACID
• Obtained from a sugar cane, beetroot or grape extract.
• The smallest of the Alpha-Hydroxy-Acids: excellent ability to be absorbed into
the skin.
• Removes the dead cells by breaking the bonds between the lipids of the stratum
corneum: intercellular cement.
HYGROSCOPIC AND MOISTURIZING EFFECT
22. GLYCOLIC SOLUTION
INDICATION
Due to a high concentration of glycolic acid, provides
cleansing, balancing, regenerating and purifying functions.
DIRECTION FOR USE
Pour 3 capfuls (30ml) into a bowl of lukewarm water.
Soak feet for 15 minutes.
COMPOSITION
PROZYMEX HBT LS 9142: keratolytic, stimulates cell renewal
EVOSINA NA2GP: anti-mycotic, antibacterial
GLYCOLIC ACID: keratolytic
PRESENTATION
Retail: not available
Professional use: 500-ml bottle - Ref. E873
23. EXFOLIANT PEEL OFF
INDICATION
Exfoliate thoroughly due to the micro-beads and
creamy texture.
DIRECTIONS FOR USE
Perform a massage in circular movements focusing
on rough and damaged areas. Rinse it off with warm
water.
COMPOSITION
PROZYMEX HBT LS 9142: keratolytic, stimulates cell
renewal
GLYCOLIC ACID: keratolytic
ETHYLEXYLGLYCERIN: antibacterial
UREA: moisturizing, keratolytic
D-PANTHENOL: healing, repairing
PRESENTATION
Retail: not available
Professional use: 150-ml tube Ref. E874
24. PROTEOLYTIC REPAIR
INDICATION
Regeneration cream with a keratolytic effect. Genuine
treatment for calluses and cracks.
DIRECTIONS FOR USE
Massage until complete absorption focusing on heels
and damaged areas.
COMPOSITION
PROZYMEX HBT LS 9142: keratolytic, stimulates cell renewal
EVOSINA NA2GP: anti-mycotic, anti-bacterial
GLYCOLIC ACID: keratolytic
UREA: moisturizing, keratolytic
KOKUM BUTTER: ultra-nourishing, repairing
SHEA BUTTER: protective active, healing
BEESWAX: protective, antibacterial
PRESENTATION
Retail: not available
Professional use: 150-ml tube - Ref. E875
25. PODO-CLINIC MASK
INDICATION
Repairing mask, warming and relaxing effect. Nourish
dry skin in depth. Provides intense skin renewal.
DIRECTIONS FOR USE
Apply a thick layer. Carry out a long massage. Cover
the feet with an extra thick layer and put each foot in a
PODO-SOCK. Leave for 15 min. Rinse it off with warm
water.
COMPOSITION
PROZYMEX HBT LS 9142: keratolytic, stimulates cell
renewal
SALICYLIC ACID: stimulates cell renewal
WILLOW EXTRACT: rich in salicylic acid
ARNICA EXTRACT: repairing, healing
PRESENTATION
Retail: not available
Professional use: 150-ml tube - Ref. E876
26. PODO-SOCKS
INDICATION
Disposable podo-clinic socks essential to the PEDICARE treatment.
Ease the absorption of active ingredients.
DIRECTIONS FOR USE
After carrying out a long massage with PODO-CLINIC MASK E876, cover the feet
with an extra layer of mask. Leave for 15 min.
PRESENTATION
Retail: not available
Professional use: bag of
10 pairs of disposable
PODO-SOCKS - Ref. E878
27. ENZYMATIC REPAIR
INDICATION
Light cream, nourishes dry and rough skin,
repairs cracks, fights against calluses. Promotes
skin renewal.
DIRECTIONS FOR USE
Massage until complete absorption. Focus on
heels and damaged areas.
COMPOSITION
PROZYMEX HBT LS 9142: keratolytic, stimulates
cell renewal
EVOSINA NA2GP: anti-mycotic, anti-bacterial
GLYCOLIC ACID: keratolytic
PRESENTATION
Retail: 60-ml tube - Ref. E871
Professional use: not available
28. DECONGESTION REFRESH
INDICATION
Decongestion cream that comforts tired, mistreated feet.
“Ice effect” immediately removes all feelings of
heaviness, swelling and hot sensations.
DIRECTIONS FOR USE
Apply in the morning or at any time of the day
depending the needs. Massage from the foot up to
ankle.
COMPOSITION
PROZYMEX HBT LS 9142: keratolytic, stimulates cell
renewal
EVOSINA NA2GP: anti-mycotic, anti-bacterial
GLYCOLIC ACID: keratolytic
MENTHOL: refreshing, relieves congestion
CAMPHOR: venotonic, relieves congestion
PRESENTATION
Retail: 60-ml tube - Ref. E872
Professional use: 150-ml tube - Ref. E877
29. PROFESSIONAL TREATMENT PROTOCOL
GLYCOLIC SOLUTION BATH
E873
Pour 3 capfuls (30ml) of
GLYCOLIC SOLUTION into a
bowl of lukewarm water.
Soak feet for 15 minutes.
EXFOLIANT PEEL OFF E874
Perform a massage with circular
movements.
Focus on rough and damaged
areas.
PROTEOLYTIC REPAIR E875
Massage until complete
absorption.
Focus on heels and damaged
areas.
30. PROFESSIONAL TREATMENT PROTOCOL
PODO-CLINIC MASK E876
Apply a thick layer, and do a
long massage. Apply an extra
thick layer, put each foot in a
PODO-SOCK: leave for 15min.
Rinse off with warm water.
DECONGESTION
REFRESH E877
Apply to the foot and ankle,
massage until complete
absorption.
DURATION OF ONE TREATMENT = 45 minutes
1 COURSE = 4 TREATMENTS
FREQUENCY = ONCE A WEEK