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Drugs and the Brain
Whiskey bottles, and brand new cars
                                                  Ooooh that smell
Oak tree you're in my way
                                                  Can't you smell that smell
There's too much coke and too much smoke
                                                  Ooooh that smell
Look what's going on inside you
                                                  The smell of death surrounds you
Ooooh that smell
                                                  Hey, you're a fool you
Can't you smell that smell
                                                  Stick them needles in your arm
Ooooh that smell
                                                  I know I been there before
The smell of death surrounds you
                                                  One little problem that confronts you
Angel of darkness is upon you
                                                  Got a monkey on your back
Stuck a needle in your arm
                                                  Just one more fix, Lord might do the trick
So take another toke, have a blow for your nose
                                                  One hell of a price for you to get your kicks
One more drink fool, will drown you
                                                  Ooooh that smell
Ooooh that smell
                                                  Can't you smell that smell
Can't you smell that smell
                                                  Ooooh that smell
Ooooh that smell
                                                  The smell of death surrounds you
The smell of death surrounds you
                                                  Ooooh that smell
Now they call you Prince Charming
                                                  Can't you smell that smell
Can't speak a word when you're full of 'ludes
                                                  Ooooh that smell
Say you'll be all right come tomorrow
                                                  The smell of death surrounds you
But tomorrow might not be here for you
Escape.
Because of Stress. (to
help relax)
To reduce pain both
physical and
emotional (to feel
better.)
Curiosity.
Recreation-
excitement-energy.
To be social/lose
inhibitions/fit in.
Addiction.
they work! If they didn’t …
they do in fact create at least a
temporary change in how we feel and
act.
Brain Basics: The brain consists of many
different types of cells; the cells involved in
storing and processing information are called
neurons.

Your body and brain have over 100 billion
neurons that communicate with each other.
Neurons communicate with each other throughout the brain
and body by both electrical signals through the neuron and
chemical messages between them. Neurons look a lot like
trees and their form fits their function.
Think about what trees do over their life, they grow new
branches and roots. So do neurons.
Over time they grow to form
networks of communications through
their branches.
These networks create our perceptions,
thoughts, and memories.
Consider the brain then as a forest of
specialized cells (neurons) with pathways
(connections) through it that take us to
different experiences.
Some parts of the brain send or receive
messages from the body. (sensory and motor
neurons)
Some parts of the brain send and receive
messages to other parts of the brain.
Some parts of the brain are analytical while
others create our moods and emotions.
All of these connections require that the brain
use chemical signals between the various
neurons.
The chemical messages are called neurotransmitters.




The many types of neurotransmitters work on a
lock and key model.
Dopamine: A reward
neurotransmitter that
causes parts of the brain
to fire creating a
sensation of excitability,
energy, power.



 Norepinephrine: (a
 chemical in
 adrenaline) causing
 hyper-vigilance and
 excitability.




Serotonin: a
calming, relaxing, focusi
ng neurotransmitter that
is one of the most
common in the brain.
Substance P: signals pain in the brain.
Endorphins: The body’s natural pain killers.
#1 The drug can chemically
resemble and work like the
actual neurotransmitter.
#2 The drug can stimulate
neurons to release their
neurotransmitters.
#3 The drug can prevent
the reuptake of
neurotransmitters by the
signaling neuron.
This is a common drug
used at raves.
It works by blocking the
reuptake of the
neurotransmitter,
serotonin, causing an
increase in the amount of
serotonin to signal other
neurons in the brain to fire,
changing their perceptions.
The individual may then
experience increased
energy, euphoria, and the
suppression of certain
inhibitions in relating to
other people. In other
words, they get high.
So… if drugs and alcohol work like the actual
neurotransmitters or work with the brain, why
then can they be a bad choice for us?
Illegal-addictive-change
                       perception to the point of
                       intoxication causing people to
                       make poor decisions-benefit is
                       usually temporary-masks real
                       issues we need to address-many
                       have serious side effects both
                       physical and emotional.

It should also be
noted that drugs
also can cause
serious imbalance
in neurotransmitter
levels in the brain.
When the brain chemistry becomes out of
balance this can lead to mental/emotional
 disease and other brain disorders. These
     changes can become long lasting.
Prescription drugs to individuals suffering from a physical or
mental disorder. They are controlled, monitored and legal.
Many carry with them side effects. Despite side effects, the
benefits can outweigh the detriments of the drug.
If drugs and alcohol work by imitating, or
releasing more neurotransmitters; doesn’t
that mean the brain must already have
the ability to achieve feelings of
relaxation, well being, energy and
excitability on its own?
Our brain has the potential
to reward itself.
This is how we are often
motivated to do things that
require effort.
Many people already take
advantage of this on some
level. You can too!
Natural High
Legal in all 50 states. 




Created by your own brain chemistry without the use
of drugs or alcohol.
Work by the release of neurotransmitters under
authentic experiences.
Are free of harmful physical and mental side effects.
Can create positive addictions that benefit the overall
well being of the individual.
When we help others
our brain releases
endorphins, and the neurotransmitter dopamine,
these neurotransmitters hit a brain reward button.
Regular daily meditation can create tremendous
feelings of well being, peace and tranquility that carry
over into the rest of your day. How does it do it?
Regular strenuous exercise elevates energy, mood,
endurance, and tremendous mind and body benefits.
How does it do it?
College Study
In a controlled study, college students who exercised
regularly decreased their binge drinking by 30%.
Those who meditated decreased their binge drinking by
30%.
Those who both meditated and exercised regularly
decreased their binge drinking by 60%.
How does it do that?
Hobbies/avocations let us escape the
everyday stressors.
Attending shows/concerts/movies.
Performing
music/plays/comedy/sporting events.
Travel
Listening to music.
Writing & Reading
Getting a massage
Pets
Being outdoors
Falling in Love
Celebrations/parties
Dancing
Creating art.
With whom do you spend
he most time?
Natural highs require some effort,
knowledge and commitment.
  Find something you want and like
  to do.
  Work at it, practice it, learn about
  it.
  And you will be able to better
  achieve …
Health!

                                       Success!




              Friendships/Love!

Well Being!

                                  Happiness!
Enjoy your brain and exploit its potential to bring
you peace of mind, happiness, and physical well
being for a lifetime.

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2.8 2013 clrm brain studies

  • 2. Whiskey bottles, and brand new cars Ooooh that smell Oak tree you're in my way Can't you smell that smell There's too much coke and too much smoke Ooooh that smell Look what's going on inside you The smell of death surrounds you Ooooh that smell Hey, you're a fool you Can't you smell that smell Stick them needles in your arm Ooooh that smell I know I been there before The smell of death surrounds you One little problem that confronts you Angel of darkness is upon you Got a monkey on your back Stuck a needle in your arm Just one more fix, Lord might do the trick So take another toke, have a blow for your nose One hell of a price for you to get your kicks One more drink fool, will drown you Ooooh that smell Ooooh that smell Can't you smell that smell Can't you smell that smell Ooooh that smell Ooooh that smell The smell of death surrounds you The smell of death surrounds you Ooooh that smell Now they call you Prince Charming Can't you smell that smell Can't speak a word when you're full of 'ludes Ooooh that smell Say you'll be all right come tomorrow The smell of death surrounds you But tomorrow might not be here for you
  • 3. Escape. Because of Stress. (to help relax) To reduce pain both physical and emotional (to feel better.) Curiosity. Recreation- excitement-energy. To be social/lose inhibitions/fit in. Addiction.
  • 4.
  • 5. they work! If they didn’t … they do in fact create at least a temporary change in how we feel and act.
  • 6. Brain Basics: The brain consists of many different types of cells; the cells involved in storing and processing information are called neurons. Your body and brain have over 100 billion neurons that communicate with each other.
  • 7. Neurons communicate with each other throughout the brain and body by both electrical signals through the neuron and chemical messages between them. Neurons look a lot like trees and their form fits their function. Think about what trees do over their life, they grow new branches and roots. So do neurons.
  • 8. Over time they grow to form networks of communications through their branches.
  • 9. These networks create our perceptions, thoughts, and memories. Consider the brain then as a forest of specialized cells (neurons) with pathways (connections) through it that take us to different experiences.
  • 10. Some parts of the brain send or receive messages from the body. (sensory and motor neurons) Some parts of the brain send and receive messages to other parts of the brain. Some parts of the brain are analytical while others create our moods and emotions. All of these connections require that the brain use chemical signals between the various neurons.
  • 11. The chemical messages are called neurotransmitters. The many types of neurotransmitters work on a lock and key model.
  • 12. Dopamine: A reward neurotransmitter that causes parts of the brain to fire creating a sensation of excitability, energy, power. Norepinephrine: (a chemical in adrenaline) causing hyper-vigilance and excitability. Serotonin: a calming, relaxing, focusi ng neurotransmitter that is one of the most common in the brain.
  • 13. Substance P: signals pain in the brain. Endorphins: The body’s natural pain killers.
  • 14. #1 The drug can chemically resemble and work like the actual neurotransmitter. #2 The drug can stimulate neurons to release their neurotransmitters. #3 The drug can prevent the reuptake of neurotransmitters by the signaling neuron.
  • 15. This is a common drug used at raves. It works by blocking the reuptake of the neurotransmitter, serotonin, causing an increase in the amount of serotonin to signal other neurons in the brain to fire, changing their perceptions. The individual may then experience increased energy, euphoria, and the suppression of certain inhibitions in relating to other people. In other words, they get high.
  • 16. So… if drugs and alcohol work like the actual neurotransmitters or work with the brain, why then can they be a bad choice for us?
  • 17. Illegal-addictive-change perception to the point of intoxication causing people to make poor decisions-benefit is usually temporary-masks real issues we need to address-many have serious side effects both physical and emotional. It should also be noted that drugs also can cause serious imbalance in neurotransmitter levels in the brain.
  • 18. When the brain chemistry becomes out of balance this can lead to mental/emotional disease and other brain disorders. These changes can become long lasting.
  • 19. Prescription drugs to individuals suffering from a physical or mental disorder. They are controlled, monitored and legal. Many carry with them side effects. Despite side effects, the benefits can outweigh the detriments of the drug.
  • 20. If drugs and alcohol work by imitating, or releasing more neurotransmitters; doesn’t that mean the brain must already have the ability to achieve feelings of relaxation, well being, energy and excitability on its own?
  • 21. Our brain has the potential to reward itself. This is how we are often motivated to do things that require effort. Many people already take advantage of this on some level. You can too!
  • 23. Legal in all 50 states.  Created by your own brain chemistry without the use of drugs or alcohol. Work by the release of neurotransmitters under authentic experiences. Are free of harmful physical and mental side effects. Can create positive addictions that benefit the overall well being of the individual.
  • 24.
  • 25. When we help others our brain releases endorphins, and the neurotransmitter dopamine, these neurotransmitters hit a brain reward button.
  • 26. Regular daily meditation can create tremendous feelings of well being, peace and tranquility that carry over into the rest of your day. How does it do it?
  • 27. Regular strenuous exercise elevates energy, mood, endurance, and tremendous mind and body benefits. How does it do it?
  • 28. College Study In a controlled study, college students who exercised regularly decreased their binge drinking by 30%. Those who meditated decreased their binge drinking by 30%. Those who both meditated and exercised regularly decreased their binge drinking by 60%. How does it do that?
  • 29. Hobbies/avocations let us escape the everyday stressors.
  • 30. Attending shows/concerts/movies. Performing music/plays/comedy/sporting events. Travel Listening to music. Writing & Reading Getting a massage Pets Being outdoors Falling in Love Celebrations/parties Dancing Creating art. With whom do you spend he most time?
  • 31. Natural highs require some effort, knowledge and commitment. Find something you want and like to do. Work at it, practice it, learn about it. And you will be able to better achieve …
  • 32. Health! Success! Friendships/Love! Well Being! Happiness!
  • 33. Enjoy your brain and exploit its potential to bring you peace of mind, happiness, and physical well being for a lifetime.

Editor's Notes

  1. Why do people take drugs (including alcohol)?
  2. What if every time someone took drugs or alcohol it felt like this?
  3. Based on the reasons we listed and their real effects on the mind and body, drugs must offer us something. In other words…
  4. So…How do drugs work? In order to understand how drugs work, you have to understand how neurons work.
  5. The basic neuron
  6. Just like trees neurons are dynamic: they can change over time with experiences.
  7. Neurons work together, and by signaling each other in networks, we learn to perceive our world.
  8. Many of these networks are in parts of the brain that are specialized for different processing and perceptions
  9. The way to understanding drug’s effects on the brain is to understand the chemical messages being sent by Neurons. Do you know the name of the chemical messengers in the brain?
  10. You may have heard of some of the types of neurotransmitters.
  11. All neurotransmitters have specific functions and roles in the brain. Science has identified over 100 different types of neurotransmitters but predict there may be many more.
  12. So… how do neurotransmitters relate to the way drugs and alcohol work on our brains?
  13. It is important to note that some drugs can actually provide benefits to certain individuals.
  14. Obviously the answer is yes!
  15. What is it called when we do something without the use of drugs/alcohol that makes us feel good, happy, relaxed, excited, or content?
  16. Natural Highs … lead to positive addictions. (after slide animations) what are ways to achieve natural highs and what are some positive addictions?
  17. Doing exciting things can release adrenaline and dopamine creating a controlled rush of energy and euphoria.
  18. Because we are complex social organisms we have evolved a brain that allows us to reward ourselves for doing things for others.
  19. Meditation releases stress by reducing/balancing stress hormones and releasing serotonin throughout the brain.
  20. Regular strenuous exercise creates a complex natural high, releasing endorphins, dopamine and serotonin.
  21. They keep us in the moment. They provide us with something to anticipate.Release dopamine, serotonin, adrenaline.
  22. Other Natural Highs (before animation) spending time with your best friend, and there are many more.
  23. So why don’t people just use natural highs instead of drugs and alcohol?
  24. What are the side effects associated with Stress Reduction & Wellness management