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ROBB FRALEY, PH.D.
CHIEF TECHNOLOGY OFFICER


GOLDMAN SACHS TENTH ANNUAL
AGRICULTURAL BIOTECH FORUM
February 14, 2006




                             1
Forward-Looking Statements




Certain statements contained in this presentation are “forward-looking statements,” such as statements concerning
the company’s anticipated financial results, current and future product performance, regulatory approvals,
business and financial plans and other non-historical facts. These statements are based on current expectations
and currently available information. However, since these statements are based on factors that involve risks and
uncertainties, the company’s actual performance and results may differ materially from those described or implied
by such forward-looking statements. Factors that could cause or contribute to such differences include, among
others: continued competition in seeds, traits and agricultural chemicals; the company’s exposure to various
contingencies, including those related to intellectual property protection, regulatory compliance and the speed with
which approvals are received, and public acceptance of biotechnology products; the success of the company’s
research and development activities; the outcomes of major lawsuits, including proceedings related to Solutia Inc.;
developments related to foreign currencies and economies; successful completion and operation of recent and
proposed acquisitions; fluctuations in commodity prices; compliance with regulations affecting our manufacturing;
the accuracy of the company’s estimates related to distribution inventory levels; the company’s ability to fund its
short-term financing needs and to obtain payment for the products that it sells; the effect of weather conditions,
natural disasters and accidents on the agriculture business or the company’s facilities; and other risks and factors
detailed in the company’s filings with the SEC. Undue reliance should not be placed on these forward-looking
statements, which are current only as of the date of this release. The company disclaims any current intention or
obligation to update any forward-looking statements or any of the factors that may affect actual results.
Trademarks
Roundup, Roundup Ready, Roundup Ready2Yield, Bollgard, Bollgard II, YieldGard, Monsanto, Imagine, Vine
Design, Asgrow, DEKALB, Monsanto Choice Genetics, Posilac, Processor Preferred, and Vistive are trademarks
owned by Monsanto Company and its wholly-owned subsidiaries and are italicized the first time they appear in this
presentation. Mavera™ is a trademark of Renessen.


                                                                                                                       2
Non-GAAP Financial Information




This presentation may use the non-GAAP financial measures of “free cash flow,” earnings per share (EPS) on an
ongoing basis, and Return on Capital (ROC). We define free cash flow as the total of cash flows from operating
activities and investing activities. A non-GAAP EPS financial measure, which we refer to as on-going EPS, excludes
certain after-tax items that we do not consider part of ongoing operations, which are identified in the reconciliation.
ROC means net income (without the effect of certain items) exclusive of after-tax interest expenses, divided by the
average of the beginning year and ending year net capital employed, as defined in the reconciliation. Our
presentation of non-GAAP financial measures is intended to supplement investors’ understanding of our operating
performance. These non-GAAP financial measures are not intended to replace net income (loss), cash flows,
financial position, or comprehensive income (loss), as determined in accordance with accounting principles
generally accepted in the United States. Furthermore, these non-GAAP financial measures may not be comparable
to similar measures used by other companies. The non-GAAP financial measures used in this presentation are
reconciled to the most directly comparable financial measures calculated and presented in accordance with GAAP,
which can be found at the end of this presentation.
Fiscal Year
In this presentation, unless otherwise specified, references to Monsanto’s fiscal years refer to the 12-month period
ending August 31.
Trademarks
Roundup, Roundup Ready, Roundup Ready2Yield, Bollgard, Bollgard II, YieldGard, Monsanto, Imagine, Vine
Design, Asgrow, DEKALB, Monsanto Choice Genetics, Posilac, Processor Preferred, Vistive, and French Kiss are
trademarks owned by Monsanto Company and its wholly-owned subsidiaries and are italicized the first time they
appear in this presentation.
Mavera™ is a trademark of Renessen.

                                                                                                                          3
OVERVIEW

Breeding and Biotech Provide Parallel R&D Paths to
Commercial Products


   BREEDING and BIOTECHNOLOGY form two R&D pathways
   Separate, but parallel, the BREEDING and BIOTECHNOLOGY pathways are linked
   by shared tools.


                 DISCOVERY          PHASE I             PHASE II
    R&D PHASE:                                                          PHASE III     PHASE IV       LAUNCH




                                              BREEDING




                                                                                        COMMERCIAL
                                                          IT PLATFORM
                                            GERMPLASM




                                                                          ANALYTICS
                                  MARKERS
                       GENOMICS




                                                                                                     SEED
                                               ELITE




Germplasm                                                                                            SOLD TO
                                                                                                     FARMERS
           R

                                    BIOTECHNOLOGY

                                                                                                               4
OVERVIEW

        Combination of Predictable Progress and Early-Phase
        Additions Created Milestone Year Across Pipeline
                                                                                          R&D PIPELINE SCORECARD
                                                                                        KEY METRICS MEASURING PIPELINE PROGRESS

                                                                             2005 PERFORMANCE
                               December   No
                         ry                  v
                    ua                           em
                      PORTFOLIO ber
                  an                                                                BIOTECH TRAIT PIPELINE
              J
                       UPDATE
             PRIORITY          DATA                                                                          Fifteen projects either advanced from one
        ry




                                                      Oc
    rua




             UPDATE                                                                                          phase to another or were added to the
                           ANALYSIS
                                                         tob

                                                                                     PIPELINE PROGRESS
   b




                                                                                                             pipeline, representing positive movement
Fe




                                                             e
                                                             r

                                                                                                             in >50% of current pipeline projects
                                                                 September
March




                                                                                                             Ten projects were added to Phase I or later
                                            DATA
                                                                                     PIPELINE ADDITIONS      as a result of Discovery work or
                                      COLLECTION                                                             collaborative partnerships

                                                                                    BREEDING PIPELINE
Ap




                                                           t
                                                        us
   ri




                                                         g
    l




                                                      Au




                                                                                                             Field trial yield differentials versus
                               FIELD                                                 CORN BREEDING           competitors even greater than in 2004
             Ma
                              TESTING
               y                                 ly                                                          First-generation molecular breeding
                                            Ju
                                                                                                             varieties showed better yield results than
                               June
                                                                                     SOYBEAN BREEDING        current competitive commercial set in field
        ANNUAL R&D CYCLE:                                                                                    trials

          SEEDS & TRAITS                                                                                     Breeding effort strengthens Stoneville’s
                                                                                     COTTON BREEDING         offerings and enables entrance of Cotton
                                                                                                             States into cotton germplasm market
                                                                                                             Strong breeding base in place, currently
                                                                                                             working on targets across farmer,
                                                                                     SEMINIS BREEDING        processor and consumer segments, as
                                                                                                             well as converting open-pollinated crops




                                                                                                                                                           5
PIPELINE UPDATE

  Corn Germplasm Improvements Are Tightly Linked to
  Market Share Gains                     U.S.
                                                   KEY MARKET ACRES                                                        BRAZIL ARGENTINA
                                                                                               BRAND LICENSED      ASI

                       Corn breeding                                                                       80M               30M                6M
                                                   AVAILABLE MARKET

 CREATING VALUE                                                                                 16%        32%     3%        35%                49%
                                                   PERCENT PENETRATED

                                                                                               2005 CORN YIELD (BU/A)
                PROJECT UPDATE                                                                                                MONSANTO BRANDS
                                                                                         200
                                                                                                                              COMPETITORS
                                           Corn Breeding                                 190

2005 PERFORMANCE                                                                         180




                                                             RESULTS
• Average yield differential of Monsanto versus
                                                                                         170
  competitors’ best material is better than one-third
  greater in 2005 compared with 2004 testing
                                                                                         160
• Strong yield advantages are consistent across maturity
  zones and outperform best competitive commercial                                       150
  material sold in 2005                                                                        95       100     105      110          115
                                                                                                      RELATIVE MATURITIES (DAYS)
2006 FOCUS
                                                                                           CORN PIPELINE HYBRID PERFORMANCE (110 RM)
• Continue marker-based breeding approach                                                120

• Continue focus on broadening genetic base of                                           115
                                                                       SELECTION INDEX
  commercial products, including strengthening our                                       110
  international portfolio
                                                             RESULTS



                                                                                         105
• On pace to gain market share in U.S. corn seed for fifth                               100
  consecutive year                                                                        95

                                                                                          90

                                                                                          85
                                                                                          MONSANTO    MONSANTO     OTHER MONSANTO           COMPETITIVE
                                                                                         COMMERCIAL   NEW 2006     PIPELINE HYBRIDS             HYBRID
                                                                                            LEADERS   HYBRIDS                                  LEADERS



                                                                                                                                                          6
PIPELINE UPDATE

 Cotton Breeding Program Provides Rich Source of Germplasm
 to Branded and Licensed Businesses                 U.S.
                                                                                                                                       COTTON
                                                                                                                    STONEVILLE
                                                                                               KEY MARKET ACRES                        STATES

                       Cotton breeding                                                                                           14M
                                                                                               AVAILABLE MARKET

 CREATING VALUE                                                                                                        14%               0%
                                                                                               PERCENT PENETRATED


                 PROJECT UPDATE                                                            2005 COTTON GERMPLASM PERFORMANCE
                                                                                                      (19 LOCATIONS)
                                          Cotton Breeding                               1600

                                                                                        1400
2005 PERFORMANCE
                                                                                        1200
• Monsanto varieties competitive with current market




                                                                        LBS LINT/ACRE
                                                                                        1000
  leaders and include Roundup Ready Flex stacked with
  Bollgard II                                                                            800
• Stoneville will offer 9 varieties either with the Roundup                              600




                                                              RESULTS
  Ready Flex trait or with Roundup Ready Flex stacked
                                                                                         400
  with Bollgard II
                                                                                         200
• Cotton States will have 5 licensees in 2006
                                                                                           0
                                                                                                                                 2005
                                                                                                     MONSANTO
2006 FOCUS
                                                                                                                             COMPETITIVE
                                                                                                     VARIETIES
                                                                                                                               LEADERS
• Introduce 4-6 new, improved varieties with latest trait
  offerings
• Continue marker-based breeding approach
• Expand breeding program and evaluations of additional
  varieties




                                                                                                                                                7
COMMERCIAL OPPORTUNITY


Seminis Addition to Monsanto Quickly Contributes to Growth
And Opens New Business and Research Opportunities

                             EUROPE-AFRICA
                                              2005
                          Market Share        19%
                          Market Position        1
                                                                 ASIA-PACIFIC
    NORTH AMERICA
                                                                              2005
                   2005
                                                            Market Share        7%
 Market Share      34%
                                                            Market Position     3
 Market Position    1



                                                                                              OPPORTUNITY
                                                                                     Fruit & vegetable seeds only
                                                                                     represent approximate
                                                                                     farmgate value (corn: 13.2%;
                                                                                     soybeans: 11.4%)
                                                                                     Significant growth
                                                                                     opportunities in hybrid
                                                                                     creation
                                                                                     Seminis has the largest
                                   SOUTH AMERICA
                                                                                     global vegetable germplasm
                                                     2005
                                                                                     library; molecular breeding
                               Market Share          37%
                                                                                     tools honed in row crops
                               Market Position        1
                                                                                     will be applied to vegetables


                                                                                                                     8
LEADERSHIP

     Efficient Discovery Program Is in Full Gear, Fueling
     Pipeline Expansion and Performance
                                                                                          PHASE II                        PHASE III
                       DISCOVERY                        PHASE I                                                                                            PHASE IV
                                                                                          Early Development               Advanced
                                                        Proof Of Concept                                                                                   Pre-launch
                       Gene/Trait                                                                                         Development
                       Identification
  AVERAGE
                           24 to 48 MONTHS                  12 to 24 MONTHS                  12 to 24 MONTHS                  12 to 24 MONTHS                  12 to 36 MONTHS
  DURATION1

  AVERAGE
                              5 PERCENT                        25 PERCENT                       50 PERCENT                       75 PERCENT                       90 PERCENT
  PROBABILITY
  OF SUCCESS2




                                                                                                                                                                          ION
                                                                                                                                                                       AT
                                                                                                                                                                    GR
                                                                                                                                                                   E
                                                                                                                                                                INT
                                                                                                                                                          AIT
                                                                                                                                                        TR
                                                                                                                                                                       ING
                                                                                                                                                                  TEST
                                                                                                                                                              D
                                                                                                                                                          FIEL
                             MONSANTO
                             DISCOVERY +                                                                                                    REGULATORY DATA GENERATION
                             COLLABORATIVE                                                                                                      REG
                                                                                                                                                   ULA
                             PARTNERS                                                                                                                 TOR
                                                                                                                                                         Y SU
                                                                                                                                                              BMIS
                                                                                                                                                                   SION
                                                                                               KEY INFLECTON POINT:                                   SE
                                                                                                                                                        ED
                                                                                                                                                           BU
                                                                                               AFTER PHASE II COMMERCIAL                                     LK
                                                                                                                                                                UP
                                                                                               SUCCESS GOES TO >50%
                                                                                               WITH LEADS ON COMMERCIAL
                                                                                               TRACK

                        TENS OF THOUSANDS                      THOUSANDS                              10s                              <5                                1
  GENES IN
  TESTING

                       •HIGH-THROUGHPUT                 •GENE OPTIMIZATION                •TRAIT                          •TRAIT INTEGRATION               •REGULATORY
  KEY ACTIVITY
                        SCREENING                                                          DEVELOPMENT                                                      SUBMISSION
                                                        •CROP                                                             •FIELD TESTING
                       •MODEL CROP                       TRANSFORMATION                   •PRE-REGULATORY                                                  •SEED BULK-UP
                                                                                                                          •REGULATORY DATA
                        TESTING                                                            DATA                            GENERATION                      •PRE-MARKETING
                                                                                          •LARGE-SCALE
                                                                                           TRANSFORMATION
1. Time estimates are based on our experience; they can overlap. Total development time for any particular product may be shorter or longer than the time estimated here.
2. This is the estimated average probability that the traits will ultimately become commercial products, based on our experience. These probabilities may change over time.
                                                                                                                                                                                 9
LEADERSHIP

Monsanto Is Upgrading the Entire Commercial Trait
Portfolio to Second- and Third-Generation Traits
                                                 TECHNOLOGY UPGRADES IN THE PIPELINE
                                                                                                                                           CORE FIRST-
                                                                                                                  COMMERCIALIZED
DISCOVERY          PHASE I               PHASE II                PHASE III                PHASE IV
                                                                                                                                           GENERATION
                                                                                                                  SECOND-
                   Proof Of Concept      Early Development       Advanced Development     Pre-launch
Gene/Trait
                                                                                                                                           TECHNOLOGY
                                                                                                                  GENERATION
Identification


                                                                                                                                              YIELDGARD CORN
                                                                   2ND GEN YIELDGARD
                                                                                                                                                   BORER
                                                                       CORN BORER
                                                                                                                                                   (1997)
                                                                 UPGRADE: BROADER                                                          BENEFIT: FULL-SEASON
                                                                 INSECT CONTROL;                                                           CONTROL OF EUROPEAN
                                                                 BETTER IRM PROPERTIES                                                     CORN BORER


                                                                                                                                              ROUNDUP READY
                                                                                                                      ROUNDUP READY
                                                                                                                                                  CORN
                                                                                                                         CORN 2
                                                                                                                                                  (1998)
                                                                                                                          (2001)
                                                                                                                                           BENEFIT: NEW WEED
                                                                                                                  UPGRADE: SIMPLIFIED
                                                                                                                                           CONTROL SYSTEM
                                                                                                                  WEED CONTROL,
                                                                                                                  GREATER FLEXIBILITY

                                                                                                                                                YIELDGARD
                      YIELDGARD                                                            2ND GEN YIELDGARD
                                                                                                                                                ROOTWORM
                     ROOTWORM II                                                               ROOTWORM
                                                                                                                                                  (2003)
                 UPGRADE: NEW MODE OF                                                    UPGRADE: IMPROVED                                 BENEFIT: CONTROL OF
                 ACTION FOR INSECT                                                       EFFICIENCY OF STACKING                            CORN ROOTWORM
                 CONTROL                                                                 IN ELITE GERMPLASM


                                                                                                                                              ROUNDUP READY
                                                                        ROUNDUP
                                           DICAMBA-TOLERANT
                                                                                                                                                SOYBEANS
                                                                      RREADY2YIELD
                                               SOYBEANS
                                                                                                                                                  (1996)
                                                                        SOYBEANS
                                          UPGRADE: ADDITIONAL                                                                              BENEFIT: NEW WEED
                                                                  UPGRADE: GREATER
                                          MODE OF ACTION                                                                                   CONTROL SYSTEM
                                                                  FLEXIBILITY; YIELD
                                                                  BENEFIT


                                                                                                                                                 BOLLGARD
                                                                                                                       BOLLGARD II
                                              BOLLGARD III
                                                                                                                                                  COTTON
                                                                                                                         COTTON
                                                COTTON
                                                                                                                                                   (1996)
                                                                                                                          (2003)
                                         BENEFIT: BROADER
                                                                                                                                           BENEFIT: IN-PLANT
                                                                                                                  BENEFIT: BROADER
                                         INSECT CONTROL;
                                                                                                                                           CONTROL OF THE
                                                                                                                  INSECT CONTROL;
                                         BETTER IRM PROPERTIES
                                                                                                                                           BOLLWORM
                                                                                                                  BETTER IRM PROPERTIES


                                                                                                                                              ROUNDUP READY
                                                                                                                     ROUNDUP READY
                     DICAMBA-TOLERANT
                                                                                                                                                 COTTON
                                                                                                                      FLEX COTTON
                          COTTON
                                                                                                                                                  (1997)
                                                                                                                         (2006)
                   BENEFIT: ADDITIONAL                                                                                                     BENEFIT: NEW WEED
                                                                                                                  BENEFIT: GREATER
                   MODE OF ACTION                                                                                                          CONTROL SYSTEM
                                                                                                                  FLEXIBILITY; HERBICIDE
                                                                                                                  REPLACEMENT


                                                                                                                                                                  10
LEADERSHIP

   Roundup Ready Flex Launch To Be Most Significant in
   10-Year History of Biotech Traits
                                                                          KEY MARKET ACRES           U.S.     INDIA    AUSTRALIA

                        Roundup Ready                                                                         10-15M
                                                                          AVAILABLE MARKET          10-15M              0.5-0.8M

                        Flex Cotton
      2006 STATUS
                                                                                                                          0%
                                                                                                      0%       0%
                                                                          PERCENT PENETRATED

                                    Anticipated trait launch of 2-3 million acres in U.S. in 2006 through 10 cotton
     ROUNDUP READY
      FLEX COTTON
         (2006)                     seed suppliers
• Pricing at a                      Roundup Ready Flex will be only stacked with Bollgard II at approximately
  premium of $6-$11                 70-80% of mix
  an acre over the
                                    Introductory acres planted in Australia; full launch set for 2007
  first-generation of
  Roundup Ready                     Trait in initial breeding phase with licensees in India in preparation for filing
  cotton                            for regulatory field trials


                                                             The Roundup Ready
                                                              Flex cotton trait will
                                                              be coupled with our
                                                             Stoneville brand and
                                                                our Cotton States
                                                                    licensing as a
                                                                      showcase of
                                                               Monsanto’s cotton
                                                                       business




                        DISCOVERY      PHASE I                                PHASE III
                                                          PHASE II                               PHASE IV           LAUNCH
                                       Proof of Concept                       Adv. Development
                                                          Early Development                      Pre-Launch

                                                                                                                                   11
LEADERSHIP

Within Discovery Platforms, Products Are Maturing into
Families
                                                   TECHNOLOGY UPGRADES IN THE PIPELINE
                                                                                                                                             FIRST-
  DISCOVERY        PHASE I                     PHASE II                 PHASE III                 PHASE IV           COMMERCIALIZED
                                                                                                                                             GENERATION
                                                                                                                     SECOND-
                   Proof Of Concept            Early Development        Advanced                  Pre-launch
  Gene/Trait
                                                                        Development
                                                                                                                                             TECHNOLOGY
  Identification
                                                                                                                     GENERATION

                                                                                                                                                 ROUNDUP READY
                                                    DICAMBA-                  ROUNDUP
                                                                                                                                                   SOYBEANS
                                                    TOLERANT                RREADY2YIELD      2                                              1
                                                                    3   2                                                                            (1996)
                                                    SOYBEANS                  SOYBEANS

    HERBICIDE                                                                                                            ROUNDUP READY
                         DICAMBA-                                                                                                                ROUNDUP READY
                                                                                                                          FLEX COTTON
    TOLERANCE            TOLERANT                                                                                                                   COTTON
                                       3                                                                                                 2   1
                                                                                                                     2       (2006)
                          COTTON                                                                                                                     (1997)

                                                                                                                         ROUNDUP READY           ROUNDUP READY
                                                                                                                            CORN 2                   CORN
                                                                                                                                         2   1
                                                                                                                             (2001)                  (1998)


                           2nd GEN                   DROUGHT-
                                       2       1
                         DROUGHT-                  TOLERANT CORN
                       TOLERANT CORN

     STRESS              DROUGHT-
                         TOLERANT
                   1
   TOLERANCE             SOYBEANS

                         DROUGHT-
                   1     TOLERANT
                          COTTON


                          HIGHER-
                   1   YIELDING CORN


   GRAIN YIELD           NITROGEN-
                        UTILIZATION
                   1
                           CORN

                                               HIGHER-YIELDING
                                           1      SOYBEANS


                                                 VISTIVE III LOW
                                                                            VISTIVE II LOW                                                       VISTIVE LOW LIN
                                                LIN - MID OLEIC –
                                                                                                                                             1
                                                                            LIN - MID OLEIC                                                         SOYBEANS
                                                                        2                     2
                                                                    3
                                                    LOW SAT
                                                                              SOYBEANS
                                                   SOYBEANS
    HEALTHIER
                                                                               OMEGA-3
      FOODS                                                                   SOYBEANS


                                                                                                  IMPROVED-PROTEIN
                                                                                                      SOYBEANS


                                                                                                                                                                   12
LEADERSHIP

Weed Control Family Is Progressing Fastest on Multi-
Generational, Multi-Crop Offerings
                                             TECHNOLOGY UPGRADES IN THE PIPELINE
                                                                                                                               FIRST-
  DISCOVERY        PHASE I                 PHASE II                PHASE III              PHASE IV     COMMERCIALIZED
                                                                                                                               GENERATION
                                                                                                       SECOND-
                   Proof Of Concept        Early Development       Advanced               Pre-launch
  Gene/Trait
                                                                   Development
                                                                                                                               TECHNOLOGY
  Identification
                                                                                                       GENERATION

                                                                                                                                   ROUNDUP READY
                                               DICAMBA-                  ROUNDUP
                                                                                                                                     SOYBEANS
                                               TOLERANT                RREADY2YIELD   2                                        1
                                                               3   2                                                                   (1996)
                                               SOYBEANS                  SOYBEANS

    HERBICIDE                                                                                              ROUNDUP READY
                       DICAMBA-                                                                                                    ROUNDUP READY
                                                                                                            FLEX COTTON
    TOLERANCE          TOLERANT                                                                                                       COTTON
                                      3                                                                                    2   1
                                                                                                       2       (2006)
                        COTTON                                                                                                         (1997)

                                                                                                           ROUNDUP READY           ROUNDUP READY
                                                                                                              CORN 2                   CORN
                                                                                                                           2   1
                                                                                                               (2001)                  (1998)




                               Herbicide Tolerance Family
                               •          First-mover advantage has enabled
                                          development of family of products
                                          and extension into multiple crops
                               •          Expansion possible because of
                                          strength of internal discovery
                                          program and licensing relationships
                               •          Pricing on next-generation traits
                                          reflects flexibility in weed control,
                                          yield gains and other benefits that
                                          accrue to the farmer
                                                                                                                                                   13
PIPELINE UPDATE

  Second-Generation Platform Expands Soybean Weed
  Control Window, Benefits for Growers
                                                                            KEY MARKET ACRES          U.S.     BRAZIL ARGENTINA

                          Roundup RReady2Yield                                                        70M       50M       35M
                                                                            AVAILABLE MARKET

                          soybeans
 CREATING VALUE                                                                                       0%        0%            0%
                                                                            PERCENT PENETRATED


                 PROJECT UPDATE
                          Roundup RReady2Yield soybeans
DISCOVERY      PHASE I       PHASE II     PHASE III    PHASE IV




2005 PERFORMANCE
• Lead event confirmed in April of 2005




                                                                  RESULTS
• 2005 U.S. field trials confirmed target yield and wider
  window of application benefits
• Trait integration efforts started
• Implementation of marker-assisted selection
2006 FOCUS

• Continued field testing to build data for regulatory
  submissions
• Continued field testing to confirm glyphosate activity in
                                                                               2005 U.S. field tests confirmed yield targets;
  suppressing Asian rust in soybeans
                                                                            The use of marker-assisted selection helped
                                                                            teams working on trait selection

                         DISCOVERY      PHASE I            PHASE II                               PHASE IV           LAUNCH
                                                                               PHASE III
                                        Proof of Concept   Early Development                      Pre-Launch
                                                                               Adv. Development

                                                                                                                                   14
PIPELINE UPDATE

  Third-Generation of Soy Weed Control Encouraging in
  2005 Field Trials
                                                                            KEY MARKET ACRES          U.S.     BRAZIL ARGENTINA

                         Dicamba-tolerant                                                             70M       50M       35M
                                                                            AVAILABLE MARKET

                         soybeans
 CREATING VALUE                                                                                       0%        0%            0%
                                                                            PERCENT PENETRATED


                PROJECT UPDATE
                                                                                                  WITH TRAIT
                               Dicamba-tolerant soybeans
DISCOVERY     PHASE I       PHASE II     PHASE III    PHASE IV




2005 PERFORMANCE
• Third-generation project enters pipeline in Phase II as a
  result of University of Nebraska collaboration




                                                                 RESULTS
  announced in 2005
• Predicted value added in the range of $2.50-$12/acre,
  depending on the weed spectrum
                                                                              WITHOUT
2006 FOCUS                                                                     TRAIT

• Continue to screen events in field conditions,
  screening for leads with commercial potential                               Tolerance demonstrated at both pre-emergence
                                                                           and post-emergence application timing, with no
                                                                           visual crop injury at rates of 1.5lb/acre, which is
                                                                           three times the labeled use rate (above)



                        DISCOVERY      PHASE I            PHASE II                                PHASE IV           LAUNCH
                                                                               PHASE III
                                       Proof of Concept   Early Development                       Pre-Launch
                                                                               Adv. Development

                                                                                                                                   15
LEADERSHIP

Stress Family Has Already Entered Second-Generation
Discovery, Expanded Into New Crops
                                                TECHNOLOGY UPGRADES IN THE PIPELINE
                                                                                                            FIRST-
  DISCOVERY        PHASE I                  PHASE II            PHASE III     PHASE IV     COMMERCIALIZED
                                                                                                            GENERATION
                                                                                           SECOND-
                   Proof Of Concept         Early Development   Advanced      Pre-launch
  Gene/Trait
                                                                Development
                                                                                                            TECHNOLOGY
  Identification
                                                                                           GENERATION

                           2nd GEN                DROUGHT-
                                       2    1
                         DROUGHT-               TOLERANT CORN
                       TOLERANT CORN

     STRESS              DROUGHT-
                         TOLERANT
                   1
   TOLERANCE             SOYBEANS

                         DROUGHT-
                   1     TOLERANT
                          COTTON




                               Stress Tolerance Family
                               •           Initial discovery focus on drought
                                           tolerance
                               •           Rapid pace of discovery has led to
                                           second-generation corn trait
                                           entering Phase I as first-generation
                                           advances to Phase II
                               •           Expansion already made into
                                           multiple crops



                                                                                                                         16
PIPELINE UPDATE

  Drought-Tolerant Corn Advances to Phase II Based on
  Second-Year Field Test Results
                                                                                                       KEY MARKET ACRES                  U.S.     BRAZIL ARGENTINA

                         Drought-tolerant corn                                                                                           80M       30M           6M
                                                                                                       AVAILABLE MARKET

 CREATING VALUE                                                                                                                          0%        0%            0%
                                                                                                       PERCENT PENETRATED


                PROJECT UPDATE                                                                         8




                                                                               DURING DROUGHT STRESS
                                                                                                                                                        Drought
                                       Drought-tolerant corn                                                                                         tolerance




                                                                               % IMPROVED GROWTH
                                                                                                       6                                             established
DISCOVERY     PHASE I       PHASE II      PHASE III    PHASE IV




                                                                  RESULTS
                                                                                                                                                     through plant
                                                                                                                                                     physiology
                                                                                                       4
                                                                                                                                                     (performance)
2005 PERFORMANCE
                                                                                                                                                     over three
                                                                                                       2
• Moved into Phase II                                                                                                                                years
                                                                                                              2003          2004           2005
• In second year, lead genes tested in drought conditions
  in 7 locations, broad-acre application in 10 locations
• Physiological drought tolerance repeated over past 3                                          40                                                       In multiple
  years                                                                                                                                              locations of

                                                                            % YIELD ADVANTAGE
                                                                                                                                                     drought-
                                                                                                20
2006 FOCUS                                                                                                                                           condition field
                                                                  RESULTS

                                                                                                                                                     trials, best-
• Continue to screen lead events for performance
                                                                                                       0                                             performing
• Continue commercial transformations for second                                                                                                     events show
                                                                                                               60      80          100     120
  generation of drought tolerance; Second set of genes                                                                                               significant yield
                                                                                                -20
  are being evaluated in Discovery and Phase I                                                                                                       advantage over
                                                                                                                                                     conventional
• Select optimal germplasm for drought genes
                                                                                                                                                     checks
                                                                                                -40
                                                                                                       LOCATIONS WITH INCREASING DROUGHT SEVERITY


                        DISCOVERY       PHASE I            PHASE II                                                            PHASE IV                 LAUNCH
                                                                                                           PHASE III
                                        Proof of Concept   Early Development                                                   Pre-Launch
                                                                                                           Adv. Development

                                                                                                                                                                      17
PIPELINE UPDATE



Drought-Tolerant Cotton Performance Encouraging in
Early Field Evaluation           KEY MARKET ACRES U.S.                                                               AUSTRALIA


                        Drought-Tolerant Cotton
                                                                            AVAILABLE MARKET               7M          0.5M
CREATING VALUE
                                                                                                           0%           0%
                                                                            PERCENT PENETRATED

                PROJECT UPDATE
                                                                                                                 FROM
                                  Drought-tolerant cotton
                                                                                                                GREENHOUSE
DISCOVERY     PHASE I      PHASE II      PHASE III       PHASE IV
                                                                                                                TESTING TO….
                                                                                                                      …FIRST
                                                                                              DROUGHT-             YEAR FIELD
2005 PERFORMANCE                                                                CONTROL
                                                                                              TOLERANT
                                                                                                                     TRIALS
• Drought leads are working across crops
• First leads into cotton are showing promise

2006 FOCUS

• Continue to evaluate to assess drought performance




                                                                                                                DROUGHT-
                                                                                     CONTROL
                                                                                                                TOLERANT


                   DISCOVERY          PHASE I                                   PHASE III
                                                            PHASE II                               PHASE IV       LAUNCH
                                      Proof of Concept                          Adv. Development
                                                            Early Development                      Pre-Launch

                                                                                                                               18
LEADERSHIP

Yield Family Expanding in Corn and Soy with Multiple
Approaches to Enhancing Intrinsic Yield
                                             TECHNOLOGY UPGRADES IN THE PIPELINE
                                                                                                           FIRST-
  DISCOVERY        PHASE I                 PHASE II            PHASE III     PHASE IV     COMMERCIALIZED
                                                                                                           GENERATION
                                                                                          SECOND-
                   Proof Of Concept        Early Development   Advanced      Pre-launch
  Gene/Trait
                                                               Development
                                                                                                           TECHNOLOGY
  Identification
                                                                                          GENERATION

                          HIGHER-
                   1   YIELDING CORN


   GRAIN YIELD           NITROGEN-
                        UTILIZATION
                   1
                           CORN

                                           HIGHER-YIELDING
                                       1      SOYBEANS




                               Grain Yield Family
                               •       Objective is to maximize intrinsic
                                       yield of germplasm
                               •       Nitrogen utilization in corn is lead
                                       product in the family




                                                                                                                        19
PIPELINE UPDATE

  Nitrogen Utilization Corn Emerged from Discovery
  Engine to First-Year Field Testing
                                                                                                KEY MARKET ACRES               U.S.     BRAZIL ARGENTINA

                         Nitrogen utilization corn                                                                             80M       30M              6M
                                                                                                AVAILABLE MARKET

 CREATING VALUE                                                                                                                0%        0%               0%
                                                                                                PERCENT PENETRATED


                PROJECT UPDATE
                                                                                                                                               G
                                                                                                                                                en
                                    Nitrogen utilization corn                                                                                        es
DISCOVERY     PHASE I       PHASE II      PHASE III    PHASE IV




                                                                  RESULTS
                                                                                                                                               HIGH N
                                                                                                                               MED N
                                                                                                                 LOW N
2005 PERFORMANCE
                                                                                                   Broad screens of hundreds of traits in low,
• Emerged from Discovery to Phase I field testing
                                                                                                medium and high nitrogen situations allow us to
• Lead events show roughly 10 percent increase in yield
                                                                                                identify candidates for more intensive field testing
  in multi-location field trials
                                                                                              190                                        At standard
2006 FOCUS


                                                                            YIELD (BU/ACRE)
                                                                                                                                      nitrogen rates
                                                                                              170
• Enhanced nitrogen utilization is a challenging trait, so                                                                            (120 lbs/ac) there
                                                                                                                              EVENT 1 is yield
  industrial scale genomics is continuing to identify more
                                                                  RESULTS

                                                                                              150
                                                                                                                              EVENT 2 advantage over
  leads
                                                                                                                              CONTROL conventional
• Continue to refine the gene constructs for optimal                                          130
                                                                                                                                      check
  performance
                                                                                              110
                                                                                                    0       50     100     150 200
                                                                                                         POUNDS OF N APPLIED/ACRE


                        DISCOVERY       PHASE I            PHASE II                                                        PHASE IV           LAUNCH
                                                                                                        PHASE III
                                        Proof of Concept   Early Development                                               Pre-Launch
                                                                                                        Adv. Development

                                                                                                                                                               20
PIPELINE UPDATE

  Higher-Yielding Soybeans Showing Good Results in
  Second-Year Field Tests
                                                                                             KEY MARKET ACRES            U.S.     BRAZIL ARGENTINA

                         Higher-yielding soybeans                                                                        80M        50M         35M
                                                                                             AVAILABLE MARKET

 CREATING VALUE                                                                                                          0%         0%            0%
                                                                                             PERCENT PENETRATED


                PROJECT UPDATE                                                                                                      WITH
                                                                                                                                    TRAIT
                                 Higher-yielding soybeans
DISCOVERY     PHASE I       PHASE II     PHASE III    PHASE IV




                                                                 RESULTS
                                                                                                      CONTROL
2005 PERFORMANCE
                                                                                         Higher yield potential is being validated in field
• Advanced to Phase II
                                                                                      environment versus conventional checks, with
• Tested hundreds of events in both first- and second-
                                                                                      visible plant height differences
  year field testing over approximately 20 locations
• Volume of current events in testing as a result of
                                                                                                                           2004
                                                                                        10                                                   Yield
  partnership with Mendel
                                                                                                                           2005           advantage
                                                                                             8
                                                                           YIELD ADVANTAGE
                                                                            (% OF CONTROL)
2006 FOCUS                                                                                                                                over
                                                                                                                                          conventional
                                                                 RESULTS
                                                                                             6
• Initiate commercial transformations and optimization to                                                                                 checks
  improve trait performance                                                                  4                                            improved in
                                                                                                                                          leads in
                                                                                             2
                                                                                                                                          second-year
                                                                                                                                          testing
                                                                                             0
                                                                                                   Event 1     Event 2        Event 3


                        DISCOVERY      PHASE I            PHASE II                                                  PHASE IV             LAUNCH
                                                                                                 PHASE III
                                       Proof of Concept   Early Development                                         Pre-Launch
                                                                                                 Adv. Development

                                                                                                                                                         21
LEADERSHIP

Pipeline and Commercial Prospects Are Strong, Diverse
Across Food-Trait Platforms
                                         TECHNOLOGY UPGRADES IN THE PIPELINE
                                                                                                                              FIRST-
  DISCOVERY        PHASE I             PHASE II                 PHASE III                 PHASE IV           COMMERCIALIZED
                                                                                                                              GENERATION
                                                                                                             SECOND-
                   Proof Of Concept    Early Development        Advanced                  Pre-launch
  Gene/Trait
                                                                Development
                                                                                                                              TECHNOLOGY
  Identification
                                                                                                             GENERATION
                                         VISTIVE III LOW
                                                                    VISTIVE II LOW                                                VISTIVE LOW LIN
                                        LIN - MID OLEIC –
                                                                                                                              1
                                                                    LIN - MID OLEIC                                                  SOYBEANS
                                                                2                     2
                                                            3
                                            LOW SAT
                                                                      SOYBEANS
                                           SOYBEANS
    HEALTHIER
                                                                       OMEGA-3
      FOODS                                                           SOYBEANS


                                                                                          IMPROVED-PROTEIN
                                                                                              SOYBEANS




                               Healthier Foods Family
                               •      Vistive low-linolenic soybeans to
                                      expand to 500,000 acres in 2006
                               •      Agreement signed with Solae
                                      Company to use improved-protein
                                      soybeans in a new product line
                               •      Positive progress made across the
                                      family, including Omega-3 soybeans
                                      advancing phases



                                                                                                                                                    22
PIPELINE UPDATE

  2005 Marked Successful Completion of Initial Taste,
  Smell and Oil Stability Testing for Omega-3 Soybeans
                                                                                                     KEY MARKET ACRES                U.S.    BRAZIL ARGENTINA

                         Omega-3 soybeans                                                                                            TBD       TBD         TBD
                                                                                                     AVAILABLE MARKET

 CREATING VALUE                                                                                                                       0%       0%            0%
                                                                                                     PERCENT PENETRATED


                PROJECT UPDATE                                                                       400
                                                                                                                                 Stabilized 20% SDA
                                        Omega-3 soybeans                                             350
DISCOVERY     PHASE I       PHASE II     PHASE III    PHASE IV
                                                                                                               20% SDA w/ CA
                                                                                                     300




                                                                           PEROXIDE VALUE, MEQ/KG
                                                                                                                 Stabilized Fish Oil
                                                                                                     250
2005 PERFORMANCE
                                                                                                     200
• Moved into Phase III
• Field trials continue to confirm expression of




                                                                 RESULTS
                                                                                                     150
  stearidonic acid (SDA) levels at concept targets
                                                                                                     100
• Initial sensory data superior to fish oil
                                                                                                      50
2006 FOCUS
                                                                                                       0
• Continue to screen to select the lead event for
                                                                                                           0   2   4   6   8 10 12 14 16 18 20 22 24 26 28 30
  regulatory submission                                                                                                      DAYS AT 55°C
                                                                                                       In testing for oil stability, SDA oil produced
                                                                                                    from Omega-3 soybean plants showed less
                                                                                                    oxidation – an indicator of stability – than fish oil
                                                                                                    where both oils were stabilized with commercial
                                                                                                    products

                        DISCOVERY      PHASE I            PHASE II                                                              PHASE IV            LAUNCH
                                                                                                        PHASE III
                                       Proof of Concept   Early Development                                                     Pre-Launch
                                                                                                        Adv. Development

                                                                                                                                                                  23
DISCOVERY        PHASE I            PHASE II      PHASE III     PHASE IV
     OVERVIEW
                                                                                  Proof Of Concept   Early         Advanced      Pre-launch
                                                                 Gene/Trait
                             2006 Pipeline                                                           Development   Development
                                                                 Identification
                             AS OF JANUARY 1, 2006
            Roundup Ready Flex cotton
            Roundup RReady2Yield soybeans
            Roundup RReady2Yield canola
            Dicamba-tolerant soybeans
            Dicamba-tolerant cotton
            2nd-Gen YieldGard Rootworm
            2nd-Gen YieldGard Corn Borer
            Insect-protected soybeans
            YieldGard Rootworm II
FARMER




            Soybean nematode-resistance
            Bollgard III
            Drought-tolerant corn
            2nd-Gen Drought-tolerant corn
            Higher-yielding canola
            Drought-tolerant soybeans
            Drought-tolerant cotton
            Higher-yielding corn
            Nitrogen utilization corn
            Higher-yielding soybeans
            Mavera™ High-value corn with lysine
PROCESSOR




            Mavera™ I High-value soybeans
            Mavera™ II High-value soybeans
            2nd-Gen High-value corn with lysine
            Feed Corn with balanced proteins
            High oil soybeans for processing
CONSUMER




            Improved-protein soybeans
            Vistive II Low Lin – Mid Oleic soybeans
            Vistive III Low Lin – Mid Oleic – Low Sat soybeans
            Omega-3 soybeans


                                                                                                                                              24
LEADERSHIP

             Monsanto’s Pipeline Is Balanced Across Multiple
             Market Opportunities

                                                         OMEGA 3
                                                         SOYBEANS                                                                     VISTIVE III
                         >$30/ ACRE




                                                                                                                                      SOYBEANS
                           HIGH:




                                                                                                                                                            DICAMBA-
                                                                                                                                                            TOLERANT
                                                                                                                                                            SOYBEANS

                                                                                                   DICAMBA-                                                ROUNDUP
                                                                                                                                                                                        YIELDGARD
                                                                                                   TOLERANT                                                RREADY2YIELD
                                                                                                                          BOLLGARD III
                                                                                                                                                                                        ROOTWORM II
                                                                                                   COTTON                                                  SOYBEANS

                                                                                               2ND GEN HIGH-VALUE
                                                                                                                                      VISTIVE II
                                                                                               CORN WITH LYSINE
RETAIL VALUE PER ACRE2




                                                                                                                                      SOYBEANS
                         <$30/ ACRE




                                                                                                  ROUNDUP READY
                          MEDIUM:




                                             HIGHER-        ROUNDUP                                                                                          2ND GEN
                                                                                                  FLEX COTTON
                                             YIELDING       RREADY2YIELD                                                                                     YIELDGARD
                                                                                                          FEED CORN WITH
                                             CANOLA         CANOLA                                                                                                                        NITROGEN-
                                                                                                                                                             ROOTWORM
                                                                                                          BALANCED PROTEINS                                                               UTILIZATION CORN
                                                                                                                                                             2ND GEN
                                                                                               MAVERATM II HIGH-                                                                          DROUGHT-TOLERANT
                                                                                                                                                             YIELDGARD
                                                            IMPROVED-                          VALUE SOYBEANS     DROUGHT-                                                                CORN
                                                                                                                                                             CORN BORER
                                                            PROTEIN                                               TOLERANT                                                                HIGHER-YIELDING
                                                            SOYBEANS                                              COTTON                                                                  SOYBEANS
                                      MAVERATM HIGH-VALUE                                  INSECT-                                                          SOYBEAN                       DROUGHT-
                                      CORN WITH LYSINE                                     PROTECTED                                                        NEMATODE                      TOLERANT
                                                                                           SOYBEANS                                                         RESISTANCE                    SOYBEANS
                         <$10/ ACRE
                           SMALL:




                                                                                                             HIGH OIL
                                                                                                             SOYBEANS FOR
                                      MAVERATM HIGH-
                                                                                                             PROCESSING
                                      VALUE SOYBEANS



                                       SMALL: <5M ACRES                                             MEDIUM: <20M ACRES                                               HIGH: >20M ACRES
                               TOTAL ACRE OPPORTUNITY1
1. “Total Acre Opportunity” represents the maximum acre penetration by the trait individually and as a stacked trait during the three-year span of its peak; Second- and third-generation traits may cannibalize acre
   opportunities of preceding product offerings
2. “Retail Value Per Acre” represents the per-acre average value for the individual trait in the three-year span during the trait penetration peak
                                                                                                                                                                                                                        25
OVERVIEW

  Drivers of Growth in Mid-Term and Long-Term Horizons
  Are On Track
FY2006 AND FY2007 TARGETS                                           FY2008 - FY2010
                                     2006             2007
                 2006
                                                                         LEADERSHIP
              COMMITMENT           FORECAST        COMMITMENT
              $2.35-$2.50                           $2.82-$3.00
                                  $2.35-$2.50                     Accelerate Current
EARNINGS      UP TO 20%                            20% GROWTH
                                TOWARD UPPER                      Commercial Platform
PER SHARE    GROWTH FROM                            FROM 2006
                                END OF RANGE
                 2005                              PROJECTION        Expanded long–term opportunity
                                                                     for corn traits, reflecting
FREE CASH                                                            opportunity in licensing,
             $825M - $900M      $825M - $900M      $875-$950M
FLOW                                                                 stacking and price-to-value
                                                                     strategies
KEY COMMERCIAL COMMITMENTS
                                                                  Expand in New Markets
US CORN
                1 – 2 pts           1 – 2pts
SHARE                                                                Penetration of new markets in
                                                                     Asia, Europe and South America
US RR CORN     30M ACRES          34M ACRES                          with existing traits
                                                                     New opportunity in the high-
US YGRW        8M ACRES           10M ACRES                          margin Seminis business

                                                                  Discover New Opportunities
US COTTON
              1 – 2 POINTS        1 – 2 POINTS
                                                                  Through Research
SHARE
                                                                     Refreshing of first-generation
US RR FLEX    2 – 3M ACRES       2 – 3M ACRES
                                                                     trait portfolio
AUSTRALIA                                                            Breeding programs expand our
                 80-85%
                                90% penetration
COTTON                                                               genetic footprint
               penetration
TRAITS
                                                                  Translate Growth to Value
BRAZIL RR    5 – 10 cents per   5 – 10 cents per
                                                                     Gross profit mix reflects higher-
EPS               share              share                           margin seeds and traits

                                                                                                         26
Reconciliation of Non-GAAP Financial Measures



    Reconciliation of Free Cash Flow

                                                         Fiscal Year       Fiscal Year
                                                            2006              2007
 $ Millions                                                Target            Target

 Net Cash Provided by Operations                        $1,300 - $1,375   $1,375 - $1,450

 Net Cash Provided (Required) by Investing Activities       $(475)            $(500)

        Free Cash Flow                                   $825 - $900        $875-$950
 Net Cash Provided (Required) by Financing Activities         N/A               N/A
 Net Increase in Cash and Cash Equivalents                    N/A               N/A




                                                                                            27

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CTO Rob Fraley's Agricultural Biotech Forum Presentation

  • 1. ROBB FRALEY, PH.D. CHIEF TECHNOLOGY OFFICER GOLDMAN SACHS TENTH ANNUAL AGRICULTURAL BIOTECH FORUM February 14, 2006 1
  • 2. Forward-Looking Statements Certain statements contained in this presentation are “forward-looking statements,” such as statements concerning the company’s anticipated financial results, current and future product performance, regulatory approvals, business and financial plans and other non-historical facts. These statements are based on current expectations and currently available information. However, since these statements are based on factors that involve risks and uncertainties, the company’s actual performance and results may differ materially from those described or implied by such forward-looking statements. Factors that could cause or contribute to such differences include, among others: continued competition in seeds, traits and agricultural chemicals; the company’s exposure to various contingencies, including those related to intellectual property protection, regulatory compliance and the speed with which approvals are received, and public acceptance of biotechnology products; the success of the company’s research and development activities; the outcomes of major lawsuits, including proceedings related to Solutia Inc.; developments related to foreign currencies and economies; successful completion and operation of recent and proposed acquisitions; fluctuations in commodity prices; compliance with regulations affecting our manufacturing; the accuracy of the company’s estimates related to distribution inventory levels; the company’s ability to fund its short-term financing needs and to obtain payment for the products that it sells; the effect of weather conditions, natural disasters and accidents on the agriculture business or the company’s facilities; and other risks and factors detailed in the company’s filings with the SEC. Undue reliance should not be placed on these forward-looking statements, which are current only as of the date of this release. The company disclaims any current intention or obligation to update any forward-looking statements or any of the factors that may affect actual results. Trademarks Roundup, Roundup Ready, Roundup Ready2Yield, Bollgard, Bollgard II, YieldGard, Monsanto, Imagine, Vine Design, Asgrow, DEKALB, Monsanto Choice Genetics, Posilac, Processor Preferred, and Vistive are trademarks owned by Monsanto Company and its wholly-owned subsidiaries and are italicized the first time they appear in this presentation. Mavera™ is a trademark of Renessen. 2
  • 3. Non-GAAP Financial Information This presentation may use the non-GAAP financial measures of “free cash flow,” earnings per share (EPS) on an ongoing basis, and Return on Capital (ROC). We define free cash flow as the total of cash flows from operating activities and investing activities. A non-GAAP EPS financial measure, which we refer to as on-going EPS, excludes certain after-tax items that we do not consider part of ongoing operations, which are identified in the reconciliation. ROC means net income (without the effect of certain items) exclusive of after-tax interest expenses, divided by the average of the beginning year and ending year net capital employed, as defined in the reconciliation. Our presentation of non-GAAP financial measures is intended to supplement investors’ understanding of our operating performance. These non-GAAP financial measures are not intended to replace net income (loss), cash flows, financial position, or comprehensive income (loss), as determined in accordance with accounting principles generally accepted in the United States. Furthermore, these non-GAAP financial measures may not be comparable to similar measures used by other companies. The non-GAAP financial measures used in this presentation are reconciled to the most directly comparable financial measures calculated and presented in accordance with GAAP, which can be found at the end of this presentation. Fiscal Year In this presentation, unless otherwise specified, references to Monsanto’s fiscal years refer to the 12-month period ending August 31. Trademarks Roundup, Roundup Ready, Roundup Ready2Yield, Bollgard, Bollgard II, YieldGard, Monsanto, Imagine, Vine Design, Asgrow, DEKALB, Monsanto Choice Genetics, Posilac, Processor Preferred, Vistive, and French Kiss are trademarks owned by Monsanto Company and its wholly-owned subsidiaries and are italicized the first time they appear in this presentation. Mavera™ is a trademark of Renessen. 3
  • 4. OVERVIEW Breeding and Biotech Provide Parallel R&D Paths to Commercial Products BREEDING and BIOTECHNOLOGY form two R&D pathways Separate, but parallel, the BREEDING and BIOTECHNOLOGY pathways are linked by shared tools. DISCOVERY PHASE I PHASE II R&D PHASE: PHASE III PHASE IV LAUNCH BREEDING COMMERCIAL IT PLATFORM GERMPLASM ANALYTICS MARKERS GENOMICS SEED ELITE Germplasm SOLD TO FARMERS R BIOTECHNOLOGY 4
  • 5. OVERVIEW Combination of Predictable Progress and Early-Phase Additions Created Milestone Year Across Pipeline R&D PIPELINE SCORECARD KEY METRICS MEASURING PIPELINE PROGRESS 2005 PERFORMANCE December No ry v ua em PORTFOLIO ber an BIOTECH TRAIT PIPELINE J UPDATE PRIORITY DATA Fifteen projects either advanced from one ry Oc rua UPDATE phase to another or were added to the ANALYSIS tob PIPELINE PROGRESS b pipeline, representing positive movement Fe e r in >50% of current pipeline projects September March Ten projects were added to Phase I or later DATA PIPELINE ADDITIONS as a result of Discovery work or COLLECTION collaborative partnerships BREEDING PIPELINE Ap t us ri g l Au Field trial yield differentials versus FIELD CORN BREEDING competitors even greater than in 2004 Ma TESTING y ly First-generation molecular breeding Ju varieties showed better yield results than June SOYBEAN BREEDING current competitive commercial set in field ANNUAL R&D CYCLE: trials SEEDS & TRAITS Breeding effort strengthens Stoneville’s COTTON BREEDING offerings and enables entrance of Cotton States into cotton germplasm market Strong breeding base in place, currently working on targets across farmer, SEMINIS BREEDING processor and consumer segments, as well as converting open-pollinated crops 5
  • 6. PIPELINE UPDATE Corn Germplasm Improvements Are Tightly Linked to Market Share Gains U.S. KEY MARKET ACRES BRAZIL ARGENTINA BRAND LICENSED ASI Corn breeding 80M 30M 6M AVAILABLE MARKET CREATING VALUE 16% 32% 3% 35% 49% PERCENT PENETRATED 2005 CORN YIELD (BU/A) PROJECT UPDATE MONSANTO BRANDS 200 COMPETITORS Corn Breeding 190 2005 PERFORMANCE 180 RESULTS • Average yield differential of Monsanto versus 170 competitors’ best material is better than one-third greater in 2005 compared with 2004 testing 160 • Strong yield advantages are consistent across maturity zones and outperform best competitive commercial 150 material sold in 2005 95 100 105 110 115 RELATIVE MATURITIES (DAYS) 2006 FOCUS CORN PIPELINE HYBRID PERFORMANCE (110 RM) • Continue marker-based breeding approach 120 • Continue focus on broadening genetic base of 115 SELECTION INDEX commercial products, including strengthening our 110 international portfolio RESULTS 105 • On pace to gain market share in U.S. corn seed for fifth 100 consecutive year 95 90 85 MONSANTO MONSANTO OTHER MONSANTO COMPETITIVE COMMERCIAL NEW 2006 PIPELINE HYBRIDS HYBRID LEADERS HYBRIDS LEADERS 6
  • 7. PIPELINE UPDATE Cotton Breeding Program Provides Rich Source of Germplasm to Branded and Licensed Businesses U.S. COTTON STONEVILLE KEY MARKET ACRES STATES Cotton breeding 14M AVAILABLE MARKET CREATING VALUE 14% 0% PERCENT PENETRATED PROJECT UPDATE 2005 COTTON GERMPLASM PERFORMANCE (19 LOCATIONS) Cotton Breeding 1600 1400 2005 PERFORMANCE 1200 • Monsanto varieties competitive with current market LBS LINT/ACRE 1000 leaders and include Roundup Ready Flex stacked with Bollgard II 800 • Stoneville will offer 9 varieties either with the Roundup 600 RESULTS Ready Flex trait or with Roundup Ready Flex stacked 400 with Bollgard II 200 • Cotton States will have 5 licensees in 2006 0 2005 MONSANTO 2006 FOCUS COMPETITIVE VARIETIES LEADERS • Introduce 4-6 new, improved varieties with latest trait offerings • Continue marker-based breeding approach • Expand breeding program and evaluations of additional varieties 7
  • 8. COMMERCIAL OPPORTUNITY Seminis Addition to Monsanto Quickly Contributes to Growth And Opens New Business and Research Opportunities EUROPE-AFRICA 2005 Market Share 19% Market Position 1 ASIA-PACIFIC NORTH AMERICA 2005 2005 Market Share 7% Market Share 34% Market Position 3 Market Position 1 OPPORTUNITY Fruit & vegetable seeds only represent approximate farmgate value (corn: 13.2%; soybeans: 11.4%) Significant growth opportunities in hybrid creation Seminis has the largest SOUTH AMERICA global vegetable germplasm 2005 library; molecular breeding Market Share 37% tools honed in row crops Market Position 1 will be applied to vegetables 8
  • 9. LEADERSHIP Efficient Discovery Program Is in Full Gear, Fueling Pipeline Expansion and Performance PHASE II PHASE III DISCOVERY PHASE I PHASE IV Early Development Advanced Proof Of Concept Pre-launch Gene/Trait Development Identification AVERAGE 24 to 48 MONTHS 12 to 24 MONTHS 12 to 24 MONTHS 12 to 24 MONTHS 12 to 36 MONTHS DURATION1 AVERAGE 5 PERCENT 25 PERCENT 50 PERCENT 75 PERCENT 90 PERCENT PROBABILITY OF SUCCESS2 ION AT GR E INT AIT TR ING TEST D FIEL MONSANTO DISCOVERY + REGULATORY DATA GENERATION COLLABORATIVE REG ULA PARTNERS TOR Y SU BMIS SION KEY INFLECTON POINT: SE ED BU AFTER PHASE II COMMERCIAL LK UP SUCCESS GOES TO >50% WITH LEADS ON COMMERCIAL TRACK TENS OF THOUSANDS THOUSANDS 10s <5 1 GENES IN TESTING •HIGH-THROUGHPUT •GENE OPTIMIZATION •TRAIT •TRAIT INTEGRATION •REGULATORY KEY ACTIVITY SCREENING DEVELOPMENT SUBMISSION •CROP •FIELD TESTING •MODEL CROP TRANSFORMATION •PRE-REGULATORY •SEED BULK-UP •REGULATORY DATA TESTING DATA GENERATION •PRE-MARKETING •LARGE-SCALE TRANSFORMATION 1. Time estimates are based on our experience; they can overlap. Total development time for any particular product may be shorter or longer than the time estimated here. 2. This is the estimated average probability that the traits will ultimately become commercial products, based on our experience. These probabilities may change over time. 9
  • 10. LEADERSHIP Monsanto Is Upgrading the Entire Commercial Trait Portfolio to Second- and Third-Generation Traits TECHNOLOGY UPGRADES IN THE PIPELINE CORE FIRST- COMMERCIALIZED DISCOVERY PHASE I PHASE II PHASE III PHASE IV GENERATION SECOND- Proof Of Concept Early Development Advanced Development Pre-launch Gene/Trait TECHNOLOGY GENERATION Identification YIELDGARD CORN 2ND GEN YIELDGARD BORER CORN BORER (1997) UPGRADE: BROADER BENEFIT: FULL-SEASON INSECT CONTROL; CONTROL OF EUROPEAN BETTER IRM PROPERTIES CORN BORER ROUNDUP READY ROUNDUP READY CORN CORN 2 (1998) (2001) BENEFIT: NEW WEED UPGRADE: SIMPLIFIED CONTROL SYSTEM WEED CONTROL, GREATER FLEXIBILITY YIELDGARD YIELDGARD 2ND GEN YIELDGARD ROOTWORM ROOTWORM II ROOTWORM (2003) UPGRADE: NEW MODE OF UPGRADE: IMPROVED BENEFIT: CONTROL OF ACTION FOR INSECT EFFICIENCY OF STACKING CORN ROOTWORM CONTROL IN ELITE GERMPLASM ROUNDUP READY ROUNDUP DICAMBA-TOLERANT SOYBEANS RREADY2YIELD SOYBEANS (1996) SOYBEANS UPGRADE: ADDITIONAL BENEFIT: NEW WEED UPGRADE: GREATER MODE OF ACTION CONTROL SYSTEM FLEXIBILITY; YIELD BENEFIT BOLLGARD BOLLGARD II BOLLGARD III COTTON COTTON COTTON (1996) (2003) BENEFIT: BROADER BENEFIT: IN-PLANT BENEFIT: BROADER INSECT CONTROL; CONTROL OF THE INSECT CONTROL; BETTER IRM PROPERTIES BOLLWORM BETTER IRM PROPERTIES ROUNDUP READY ROUNDUP READY DICAMBA-TOLERANT COTTON FLEX COTTON COTTON (1997) (2006) BENEFIT: ADDITIONAL BENEFIT: NEW WEED BENEFIT: GREATER MODE OF ACTION CONTROL SYSTEM FLEXIBILITY; HERBICIDE REPLACEMENT 10
  • 11. LEADERSHIP Roundup Ready Flex Launch To Be Most Significant in 10-Year History of Biotech Traits KEY MARKET ACRES U.S. INDIA AUSTRALIA Roundup Ready 10-15M AVAILABLE MARKET 10-15M 0.5-0.8M Flex Cotton 2006 STATUS 0% 0% 0% PERCENT PENETRATED Anticipated trait launch of 2-3 million acres in U.S. in 2006 through 10 cotton ROUNDUP READY FLEX COTTON (2006) seed suppliers • Pricing at a Roundup Ready Flex will be only stacked with Bollgard II at approximately premium of $6-$11 70-80% of mix an acre over the Introductory acres planted in Australia; full launch set for 2007 first-generation of Roundup Ready Trait in initial breeding phase with licensees in India in preparation for filing cotton for regulatory field trials The Roundup Ready Flex cotton trait will be coupled with our Stoneville brand and our Cotton States licensing as a showcase of Monsanto’s cotton business DISCOVERY PHASE I PHASE III PHASE II PHASE IV LAUNCH Proof of Concept Adv. Development Early Development Pre-Launch 11
  • 12. LEADERSHIP Within Discovery Platforms, Products Are Maturing into Families TECHNOLOGY UPGRADES IN THE PIPELINE FIRST- DISCOVERY PHASE I PHASE II PHASE III PHASE IV COMMERCIALIZED GENERATION SECOND- Proof Of Concept Early Development Advanced Pre-launch Gene/Trait Development TECHNOLOGY Identification GENERATION ROUNDUP READY DICAMBA- ROUNDUP SOYBEANS TOLERANT RREADY2YIELD 2 1 3 2 (1996) SOYBEANS SOYBEANS HERBICIDE ROUNDUP READY DICAMBA- ROUNDUP READY FLEX COTTON TOLERANCE TOLERANT COTTON 3 2 1 2 (2006) COTTON (1997) ROUNDUP READY ROUNDUP READY CORN 2 CORN 2 1 (2001) (1998) 2nd GEN DROUGHT- 2 1 DROUGHT- TOLERANT CORN TOLERANT CORN STRESS DROUGHT- TOLERANT 1 TOLERANCE SOYBEANS DROUGHT- 1 TOLERANT COTTON HIGHER- 1 YIELDING CORN GRAIN YIELD NITROGEN- UTILIZATION 1 CORN HIGHER-YIELDING 1 SOYBEANS VISTIVE III LOW VISTIVE II LOW VISTIVE LOW LIN LIN - MID OLEIC – 1 LIN - MID OLEIC SOYBEANS 2 2 3 LOW SAT SOYBEANS SOYBEANS HEALTHIER OMEGA-3 FOODS SOYBEANS IMPROVED-PROTEIN SOYBEANS 12
  • 13. LEADERSHIP Weed Control Family Is Progressing Fastest on Multi- Generational, Multi-Crop Offerings TECHNOLOGY UPGRADES IN THE PIPELINE FIRST- DISCOVERY PHASE I PHASE II PHASE III PHASE IV COMMERCIALIZED GENERATION SECOND- Proof Of Concept Early Development Advanced Pre-launch Gene/Trait Development TECHNOLOGY Identification GENERATION ROUNDUP READY DICAMBA- ROUNDUP SOYBEANS TOLERANT RREADY2YIELD 2 1 3 2 (1996) SOYBEANS SOYBEANS HERBICIDE ROUNDUP READY DICAMBA- ROUNDUP READY FLEX COTTON TOLERANCE TOLERANT COTTON 3 2 1 2 (2006) COTTON (1997) ROUNDUP READY ROUNDUP READY CORN 2 CORN 2 1 (2001) (1998) Herbicide Tolerance Family • First-mover advantage has enabled development of family of products and extension into multiple crops • Expansion possible because of strength of internal discovery program and licensing relationships • Pricing on next-generation traits reflects flexibility in weed control, yield gains and other benefits that accrue to the farmer 13
  • 14. PIPELINE UPDATE Second-Generation Platform Expands Soybean Weed Control Window, Benefits for Growers KEY MARKET ACRES U.S. BRAZIL ARGENTINA Roundup RReady2Yield 70M 50M 35M AVAILABLE MARKET soybeans CREATING VALUE 0% 0% 0% PERCENT PENETRATED PROJECT UPDATE Roundup RReady2Yield soybeans DISCOVERY PHASE I PHASE II PHASE III PHASE IV 2005 PERFORMANCE • Lead event confirmed in April of 2005 RESULTS • 2005 U.S. field trials confirmed target yield and wider window of application benefits • Trait integration efforts started • Implementation of marker-assisted selection 2006 FOCUS • Continued field testing to build data for regulatory submissions • Continued field testing to confirm glyphosate activity in 2005 U.S. field tests confirmed yield targets; suppressing Asian rust in soybeans The use of marker-assisted selection helped teams working on trait selection DISCOVERY PHASE I PHASE II PHASE IV LAUNCH PHASE III Proof of Concept Early Development Pre-Launch Adv. Development 14
  • 15. PIPELINE UPDATE Third-Generation of Soy Weed Control Encouraging in 2005 Field Trials KEY MARKET ACRES U.S. BRAZIL ARGENTINA Dicamba-tolerant 70M 50M 35M AVAILABLE MARKET soybeans CREATING VALUE 0% 0% 0% PERCENT PENETRATED PROJECT UPDATE WITH TRAIT Dicamba-tolerant soybeans DISCOVERY PHASE I PHASE II PHASE III PHASE IV 2005 PERFORMANCE • Third-generation project enters pipeline in Phase II as a result of University of Nebraska collaboration RESULTS announced in 2005 • Predicted value added in the range of $2.50-$12/acre, depending on the weed spectrum WITHOUT 2006 FOCUS TRAIT • Continue to screen events in field conditions, screening for leads with commercial potential Tolerance demonstrated at both pre-emergence and post-emergence application timing, with no visual crop injury at rates of 1.5lb/acre, which is three times the labeled use rate (above) DISCOVERY PHASE I PHASE II PHASE IV LAUNCH PHASE III Proof of Concept Early Development Pre-Launch Adv. Development 15
  • 16. LEADERSHIP Stress Family Has Already Entered Second-Generation Discovery, Expanded Into New Crops TECHNOLOGY UPGRADES IN THE PIPELINE FIRST- DISCOVERY PHASE I PHASE II PHASE III PHASE IV COMMERCIALIZED GENERATION SECOND- Proof Of Concept Early Development Advanced Pre-launch Gene/Trait Development TECHNOLOGY Identification GENERATION 2nd GEN DROUGHT- 2 1 DROUGHT- TOLERANT CORN TOLERANT CORN STRESS DROUGHT- TOLERANT 1 TOLERANCE SOYBEANS DROUGHT- 1 TOLERANT COTTON Stress Tolerance Family • Initial discovery focus on drought tolerance • Rapid pace of discovery has led to second-generation corn trait entering Phase I as first-generation advances to Phase II • Expansion already made into multiple crops 16
  • 17. PIPELINE UPDATE Drought-Tolerant Corn Advances to Phase II Based on Second-Year Field Test Results KEY MARKET ACRES U.S. BRAZIL ARGENTINA Drought-tolerant corn 80M 30M 6M AVAILABLE MARKET CREATING VALUE 0% 0% 0% PERCENT PENETRATED PROJECT UPDATE 8 DURING DROUGHT STRESS Drought Drought-tolerant corn tolerance % IMPROVED GROWTH 6 established DISCOVERY PHASE I PHASE II PHASE III PHASE IV RESULTS through plant physiology 4 (performance) 2005 PERFORMANCE over three 2 • Moved into Phase II years 2003 2004 2005 • In second year, lead genes tested in drought conditions in 7 locations, broad-acre application in 10 locations • Physiological drought tolerance repeated over past 3 40 In multiple years locations of % YIELD ADVANTAGE drought- 20 2006 FOCUS condition field RESULTS trials, best- • Continue to screen lead events for performance 0 performing • Continue commercial transformations for second events show 60 80 100 120 generation of drought tolerance; Second set of genes significant yield -20 are being evaluated in Discovery and Phase I advantage over conventional • Select optimal germplasm for drought genes checks -40 LOCATIONS WITH INCREASING DROUGHT SEVERITY DISCOVERY PHASE I PHASE II PHASE IV LAUNCH PHASE III Proof of Concept Early Development Pre-Launch Adv. Development 17
  • 18. PIPELINE UPDATE Drought-Tolerant Cotton Performance Encouraging in Early Field Evaluation KEY MARKET ACRES U.S. AUSTRALIA Drought-Tolerant Cotton AVAILABLE MARKET 7M 0.5M CREATING VALUE 0% 0% PERCENT PENETRATED PROJECT UPDATE FROM Drought-tolerant cotton GREENHOUSE DISCOVERY PHASE I PHASE II PHASE III PHASE IV TESTING TO…. …FIRST DROUGHT- YEAR FIELD 2005 PERFORMANCE CONTROL TOLERANT TRIALS • Drought leads are working across crops • First leads into cotton are showing promise 2006 FOCUS • Continue to evaluate to assess drought performance DROUGHT- CONTROL TOLERANT DISCOVERY PHASE I PHASE III PHASE II PHASE IV LAUNCH Proof of Concept Adv. Development Early Development Pre-Launch 18
  • 19. LEADERSHIP Yield Family Expanding in Corn and Soy with Multiple Approaches to Enhancing Intrinsic Yield TECHNOLOGY UPGRADES IN THE PIPELINE FIRST- DISCOVERY PHASE I PHASE II PHASE III PHASE IV COMMERCIALIZED GENERATION SECOND- Proof Of Concept Early Development Advanced Pre-launch Gene/Trait Development TECHNOLOGY Identification GENERATION HIGHER- 1 YIELDING CORN GRAIN YIELD NITROGEN- UTILIZATION 1 CORN HIGHER-YIELDING 1 SOYBEANS Grain Yield Family • Objective is to maximize intrinsic yield of germplasm • Nitrogen utilization in corn is lead product in the family 19
  • 20. PIPELINE UPDATE Nitrogen Utilization Corn Emerged from Discovery Engine to First-Year Field Testing KEY MARKET ACRES U.S. BRAZIL ARGENTINA Nitrogen utilization corn 80M 30M 6M AVAILABLE MARKET CREATING VALUE 0% 0% 0% PERCENT PENETRATED PROJECT UPDATE G en Nitrogen utilization corn es DISCOVERY PHASE I PHASE II PHASE III PHASE IV RESULTS HIGH N MED N LOW N 2005 PERFORMANCE Broad screens of hundreds of traits in low, • Emerged from Discovery to Phase I field testing medium and high nitrogen situations allow us to • Lead events show roughly 10 percent increase in yield identify candidates for more intensive field testing in multi-location field trials 190 At standard 2006 FOCUS YIELD (BU/ACRE) nitrogen rates 170 • Enhanced nitrogen utilization is a challenging trait, so (120 lbs/ac) there EVENT 1 is yield industrial scale genomics is continuing to identify more RESULTS 150 EVENT 2 advantage over leads CONTROL conventional • Continue to refine the gene constructs for optimal 130 check performance 110 0 50 100 150 200 POUNDS OF N APPLIED/ACRE DISCOVERY PHASE I PHASE II PHASE IV LAUNCH PHASE III Proof of Concept Early Development Pre-Launch Adv. Development 20
  • 21. PIPELINE UPDATE Higher-Yielding Soybeans Showing Good Results in Second-Year Field Tests KEY MARKET ACRES U.S. BRAZIL ARGENTINA Higher-yielding soybeans 80M 50M 35M AVAILABLE MARKET CREATING VALUE 0% 0% 0% PERCENT PENETRATED PROJECT UPDATE WITH TRAIT Higher-yielding soybeans DISCOVERY PHASE I PHASE II PHASE III PHASE IV RESULTS CONTROL 2005 PERFORMANCE Higher yield potential is being validated in field • Advanced to Phase II environment versus conventional checks, with • Tested hundreds of events in both first- and second- visible plant height differences year field testing over approximately 20 locations • Volume of current events in testing as a result of 2004 10 Yield partnership with Mendel 2005 advantage 8 YIELD ADVANTAGE (% OF CONTROL) 2006 FOCUS over conventional RESULTS 6 • Initiate commercial transformations and optimization to checks improve trait performance 4 improved in leads in 2 second-year testing 0 Event 1 Event 2 Event 3 DISCOVERY PHASE I PHASE II PHASE IV LAUNCH PHASE III Proof of Concept Early Development Pre-Launch Adv. Development 21
  • 22. LEADERSHIP Pipeline and Commercial Prospects Are Strong, Diverse Across Food-Trait Platforms TECHNOLOGY UPGRADES IN THE PIPELINE FIRST- DISCOVERY PHASE I PHASE II PHASE III PHASE IV COMMERCIALIZED GENERATION SECOND- Proof Of Concept Early Development Advanced Pre-launch Gene/Trait Development TECHNOLOGY Identification GENERATION VISTIVE III LOW VISTIVE II LOW VISTIVE LOW LIN LIN - MID OLEIC – 1 LIN - MID OLEIC SOYBEANS 2 2 3 LOW SAT SOYBEANS SOYBEANS HEALTHIER OMEGA-3 FOODS SOYBEANS IMPROVED-PROTEIN SOYBEANS Healthier Foods Family • Vistive low-linolenic soybeans to expand to 500,000 acres in 2006 • Agreement signed with Solae Company to use improved-protein soybeans in a new product line • Positive progress made across the family, including Omega-3 soybeans advancing phases 22
  • 23. PIPELINE UPDATE 2005 Marked Successful Completion of Initial Taste, Smell and Oil Stability Testing for Omega-3 Soybeans KEY MARKET ACRES U.S. BRAZIL ARGENTINA Omega-3 soybeans TBD TBD TBD AVAILABLE MARKET CREATING VALUE 0% 0% 0% PERCENT PENETRATED PROJECT UPDATE 400 Stabilized 20% SDA Omega-3 soybeans 350 DISCOVERY PHASE I PHASE II PHASE III PHASE IV 20% SDA w/ CA 300 PEROXIDE VALUE, MEQ/KG Stabilized Fish Oil 250 2005 PERFORMANCE 200 • Moved into Phase III • Field trials continue to confirm expression of RESULTS 150 stearidonic acid (SDA) levels at concept targets 100 • Initial sensory data superior to fish oil 50 2006 FOCUS 0 • Continue to screen to select the lead event for 0 2 4 6 8 10 12 14 16 18 20 22 24 26 28 30 regulatory submission DAYS AT 55°C In testing for oil stability, SDA oil produced from Omega-3 soybean plants showed less oxidation – an indicator of stability – than fish oil where both oils were stabilized with commercial products DISCOVERY PHASE I PHASE II PHASE IV LAUNCH PHASE III Proof of Concept Early Development Pre-Launch Adv. Development 23
  • 24. DISCOVERY PHASE I PHASE II PHASE III PHASE IV OVERVIEW Proof Of Concept Early Advanced Pre-launch Gene/Trait 2006 Pipeline Development Development Identification AS OF JANUARY 1, 2006 Roundup Ready Flex cotton Roundup RReady2Yield soybeans Roundup RReady2Yield canola Dicamba-tolerant soybeans Dicamba-tolerant cotton 2nd-Gen YieldGard Rootworm 2nd-Gen YieldGard Corn Borer Insect-protected soybeans YieldGard Rootworm II FARMER Soybean nematode-resistance Bollgard III Drought-tolerant corn 2nd-Gen Drought-tolerant corn Higher-yielding canola Drought-tolerant soybeans Drought-tolerant cotton Higher-yielding corn Nitrogen utilization corn Higher-yielding soybeans Mavera™ High-value corn with lysine PROCESSOR Mavera™ I High-value soybeans Mavera™ II High-value soybeans 2nd-Gen High-value corn with lysine Feed Corn with balanced proteins High oil soybeans for processing CONSUMER Improved-protein soybeans Vistive II Low Lin – Mid Oleic soybeans Vistive III Low Lin – Mid Oleic – Low Sat soybeans Omega-3 soybeans 24
  • 25. LEADERSHIP Monsanto’s Pipeline Is Balanced Across Multiple Market Opportunities OMEGA 3 SOYBEANS VISTIVE III >$30/ ACRE SOYBEANS HIGH: DICAMBA- TOLERANT SOYBEANS DICAMBA- ROUNDUP YIELDGARD TOLERANT RREADY2YIELD BOLLGARD III ROOTWORM II COTTON SOYBEANS 2ND GEN HIGH-VALUE VISTIVE II CORN WITH LYSINE RETAIL VALUE PER ACRE2 SOYBEANS <$30/ ACRE ROUNDUP READY MEDIUM: HIGHER- ROUNDUP 2ND GEN FLEX COTTON YIELDING RREADY2YIELD YIELDGARD FEED CORN WITH CANOLA CANOLA NITROGEN- ROOTWORM BALANCED PROTEINS UTILIZATION CORN 2ND GEN MAVERATM II HIGH- DROUGHT-TOLERANT YIELDGARD IMPROVED- VALUE SOYBEANS DROUGHT- CORN CORN BORER PROTEIN TOLERANT HIGHER-YIELDING SOYBEANS COTTON SOYBEANS MAVERATM HIGH-VALUE INSECT- SOYBEAN DROUGHT- CORN WITH LYSINE PROTECTED NEMATODE TOLERANT SOYBEANS RESISTANCE SOYBEANS <$10/ ACRE SMALL: HIGH OIL SOYBEANS FOR MAVERATM HIGH- PROCESSING VALUE SOYBEANS SMALL: <5M ACRES MEDIUM: <20M ACRES HIGH: >20M ACRES TOTAL ACRE OPPORTUNITY1 1. “Total Acre Opportunity” represents the maximum acre penetration by the trait individually and as a stacked trait during the three-year span of its peak; Second- and third-generation traits may cannibalize acre opportunities of preceding product offerings 2. “Retail Value Per Acre” represents the per-acre average value for the individual trait in the three-year span during the trait penetration peak 25
  • 26. OVERVIEW Drivers of Growth in Mid-Term and Long-Term Horizons Are On Track FY2006 AND FY2007 TARGETS FY2008 - FY2010 2006 2007 2006 LEADERSHIP COMMITMENT FORECAST COMMITMENT $2.35-$2.50 $2.82-$3.00 $2.35-$2.50 Accelerate Current EARNINGS UP TO 20% 20% GROWTH TOWARD UPPER Commercial Platform PER SHARE GROWTH FROM FROM 2006 END OF RANGE 2005 PROJECTION Expanded long–term opportunity for corn traits, reflecting FREE CASH opportunity in licensing, $825M - $900M $825M - $900M $875-$950M FLOW stacking and price-to-value strategies KEY COMMERCIAL COMMITMENTS Expand in New Markets US CORN 1 – 2 pts 1 – 2pts SHARE Penetration of new markets in Asia, Europe and South America US RR CORN 30M ACRES 34M ACRES with existing traits New opportunity in the high- US YGRW 8M ACRES 10M ACRES margin Seminis business Discover New Opportunities US COTTON 1 – 2 POINTS 1 – 2 POINTS Through Research SHARE Refreshing of first-generation US RR FLEX 2 – 3M ACRES 2 – 3M ACRES trait portfolio AUSTRALIA Breeding programs expand our 80-85% 90% penetration COTTON genetic footprint penetration TRAITS Translate Growth to Value BRAZIL RR 5 – 10 cents per 5 – 10 cents per Gross profit mix reflects higher- EPS share share margin seeds and traits 26
  • 27. Reconciliation of Non-GAAP Financial Measures Reconciliation of Free Cash Flow Fiscal Year Fiscal Year 2006 2007 $ Millions Target Target Net Cash Provided by Operations $1,300 - $1,375 $1,375 - $1,450 Net Cash Provided (Required) by Investing Activities $(475) $(500) Free Cash Flow $825 - $900 $875-$950 Net Cash Provided (Required) by Financing Activities N/A N/A Net Increase in Cash and Cash Equivalents N/A N/A 27