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Effect of preemptive gabapentin on postoperative pain and opioid use

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The Effect Of Preemptive Gabapentin On Postoperative Pain And Opioid Requirement Following Head And Neck Surgeries Dr Nikhil M P Dr N R Bhat Dr Prashanth mallya Dr Ambareesha M
Introduction 1* ,[object Object]
Introduction cont….2* ,[object Object]
Introduction cont…3* ,[object Object]
Preemptive analgesia 4* ,[object Object]
Gabapentin 5* ,[object Object]
Aim 6* ,[object Object]
Materials and methods 7* ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Materials and methods cont….8* ,[object Object],[object Object]
Materials and methods cont….9* ,[object Object],[object Object],[object Object]
Materials and methods cont….10* ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Materials and methods cont….11* ,[object Object],[object Object],[object Object]
Materials and methods cont….12* ,[object Object],[object Object]
Observation and results 13* ,[object Object],[object Object],[object Object]
Intergroup comparison of pain scores postoperatively for 24 hours following surgery at different time intervals Time Group N Mean Std.deviation t p value 0-6 Control Case 30 30 3.16 1.69 0.34 0.47 13.8 p=0.001 7-12 Control Case 30 30 2.35 2.05 0.67 0.53 2.094 p=0.041 13-18 Control Case 30 30 1.85 1.45 0.76 0.53 2.4 p=0.019 19-24 Control Case 30 30 1.39 1.003 0.76 0.40 2.5 p=0.015
Intergroup comparison of pain scores postoperatively for 24 hours at different time intervals
Intergroup comparison of pethidine requirement postoperatively for 24 hours Groups N Mean Std.deviation Z Control 30 163.16 39.7 6.67 Case 30 47.00 23.5 p=0.001
Intergroup comparison of pethidine requirement postoperatively for 24 hours
Intergroup comparison of heart rate postoperatively for 24 hours Time Group N Mean Std. deviation t P value 0 -6 control case 30 30 90.2 79.7 6.96 4.9 6.74 P=0.001 7-12 control case 30 30 88.46 75.86 6.5 4.9 8.41 P=0.001 13-18 control case 30 30 84.5 71.5 5.4 4.8 9.76 P=0.001 19-24 control case 30 30 79.7 69.5 8.19 4.006 6.26 P=0.001
Intergroup comparison of SBP postoperatively for 24 hours Time Group N Mea n std. deviation t p value 0-6 control case 30 30 139.8 131.2 9.03 5.18 4.52 p=0.001 7-12 control case 30 30 137.6 129.0 8.77 3.14 5.09 p=0.001 13-18 control case 30 30 134.1 125.3 8.51 4.43 5.01 p=0.001 19-24 control case 30 30 131.8 121.2 8.37 3.87 4.51 p=0.001
Intergroup comparison of DBP postoperatively for 24 hours Time Group N Mea n std. deviation t p value 0-6 control case 30 30 82.4 80.06 4.28 1.33 2.9 p=0.005 7-12 control case 30 30 82.2 79.9 5.12 1.23 2.41 p=0.019 13-18 control case 30 30 81.8 79.5 4.75 1.25 2.6 p=0.012 19-24 control case 30 30 81.06 78.4 5.1 3.37 2.35 p=0.022
Intergroup comparison of nausea postoperatively for 24 hours
Intergroup comparison of nausea postoperatively for 24 hours
Discussion 14* ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Discussion cont… ,[object Object]
Discussion cont.. ,[object Object]
Discussion cont.. ,[object Object]
Discussion cont.. ,[object Object],[object Object],[object Object]
Limitation ,[object Object],[object Object]
conclusion ,[object Object]
conclusion cont…. ,[object Object]
References ,[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 

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Effect of preemptive gabapentin on postoperative pain and opioid use

  • 1. The Effect Of Preemptive Gabapentin On Postoperative Pain And Opioid Requirement Following Head And Neck Surgeries Dr Nikhil M P Dr N R Bhat Dr Prashanth mallya Dr Ambareesha M
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  • 15. Intergroup comparison of pain scores postoperatively for 24 hours following surgery at different time intervals Time Group N Mean Std.deviation t p value 0-6 Control Case 30 30 3.16 1.69 0.34 0.47 13.8 p=0.001 7-12 Control Case 30 30 2.35 2.05 0.67 0.53 2.094 p=0.041 13-18 Control Case 30 30 1.85 1.45 0.76 0.53 2.4 p=0.019 19-24 Control Case 30 30 1.39 1.003 0.76 0.40 2.5 p=0.015
  • 16. Intergroup comparison of pain scores postoperatively for 24 hours at different time intervals
  • 17. Intergroup comparison of pethidine requirement postoperatively for 24 hours Groups N Mean Std.deviation Z Control 30 163.16 39.7 6.67 Case 30 47.00 23.5 p=0.001
  • 18. Intergroup comparison of pethidine requirement postoperatively for 24 hours
  • 19. Intergroup comparison of heart rate postoperatively for 24 hours Time Group N Mean Std. deviation t P value 0 -6 control case 30 30 90.2 79.7 6.96 4.9 6.74 P=0.001 7-12 control case 30 30 88.46 75.86 6.5 4.9 8.41 P=0.001 13-18 control case 30 30 84.5 71.5 5.4 4.8 9.76 P=0.001 19-24 control case 30 30 79.7 69.5 8.19 4.006 6.26 P=0.001
  • 20. Intergroup comparison of SBP postoperatively for 24 hours Time Group N Mea n std. deviation t p value 0-6 control case 30 30 139.8 131.2 9.03 5.18 4.52 p=0.001 7-12 control case 30 30 137.6 129.0 8.77 3.14 5.09 p=0.001 13-18 control case 30 30 134.1 125.3 8.51 4.43 5.01 p=0.001 19-24 control case 30 30 131.8 121.2 8.37 3.87 4.51 p=0.001
  • 21. Intergroup comparison of DBP postoperatively for 24 hours Time Group N Mea n std. deviation t p value 0-6 control case 30 30 82.4 80.06 4.28 1.33 2.9 p=0.005 7-12 control case 30 30 82.2 79.9 5.12 1.23 2.41 p=0.019 13-18 control case 30 30 81.8 79.5 4.75 1.25 2.6 p=0.012 19-24 control case 30 30 81.06 78.4 5.1 3.37 2.35 p=0.022
  • 22. Intergroup comparison of nausea postoperatively for 24 hours
  • 23. Intergroup comparison of nausea postoperatively for 24 hours
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