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CANALOPLASTY
FAQ
?
? ?
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Canaloplasty (pronounced Kah-NAL-oh-plas-tee)
is a new glaucoma treatment that gives many people
with this potentially blinding condition the hope of
saving the vision they have. Canaloplasty can re-
duce pressure in the eye (IOP) by nearly 40%, and
many glaucoma patients who have had Canaloplasty
no longer need medications. This “minimally inva-
sive” procedure is available alone or can be done
with cataract extraction (phacocanaloplasty). It is a
“non-penetrating” surgical procedure that does not
require creation of a fistula nor result in a “bleb”
such as with traditional trabeculectomy surgery. In-
sertion of a micro-catheter into Schlemm’s canal
(the eye’s internal drainage duct) facilitates exit of
eye fluid through the natural outflow. The canal is
then dilated by injecting a sterile, gel-like material
called a viscoelastic. After the drainage channel is
made larger the micro-catheter is removed and a
Canaloplasty Surgery
FAQ
suture is placed within the canal system. Suture ten-
sion within this system keeps it open for years re-
sulting in a controlled eye pressure.
What is Canaloplasty?
CANALOPLASTY
New GlaucomaTreatment
Go to http://new-glaucoma-treatments.com/canaloplasty/
See how Canaloplasty is done.
Watch Dr. Richardson’s video online
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Safety. Canaloplasty is safer than traditional glau-
coma surgery (trabeculectomy). If you are consid-
ering glaucoma surgery to prevent further vision
loss then choosing a surgery that has fewer risks
makes sense.
Age. Younger patients need a better option than
traditional glaucoma surgery. Traditional glaucoma
surgery is less likely to succeed in younger patients
and carries a lifetime risk of infection. Success
with Canaloplasty is not age dependent and there is
no lifetime risk of infection.
Active Lifestyle. If you are an energetic person
who enjoys such activities as watersports, it is im-
portant for you to know that having traditional
Why Canaloplasty?
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glaucoma surgery will severely limit your ability to
participate in certain sports. No such limitation ex-
ists with Canaloplasty. Once healed, patients who
have had Canaloplasty are able to return to their
previous active lifestyles without restriction or lim-
itation.
Nearsighted. People who are very nearsighted
(highly myopic) are at a much higher risk of vision-
threatening complications from traditional glauco-
ma surgeries. This is not true with Canaloplasty.
Ethnicity. Traditional glaucoma surgery has a high
failure rate among African American patients. In
contrast, Canaloplasty has a well-established track
record of success among many races.
Fear of Cataract. If you do not currently have a
cataract, you should know that the risk of devel-
oping one increases substantially after traditional
glaucoma surgery. This risk is much lower with
Canaloplasty.
Difficulty with Glaucoma Medications. If
you are having trouble tolerating or affording your
glaucoma medications, then Canaloplasty may
be an option for you. With traditional glaucoma
surgeries, the risk is just too high to consider for
reasons of financial hardship or side effects of
medicines alone.
These are just some of the many reasons to con-
sider Canaloplasty. If you have open angle glau-
coma (the most common type) and are considering
glaucoma surgery, then you should explore your
available options before making a decision. Al-
though there are certainly instances where tradi-
tional glaucoma surgery is the best (or even only )
option available, most patients with glaucoma are
candidates for Canaloplasty and should consider
this safer option.
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How long has Canaloplasty been
around? The answer to this question is
not as straightforward as it might seem. Al-
though the iTrack catheter (required to perform
canaloplasty) has only been FDA approved since
2008, the surgical technique used to perform Ca-
naloplasty has been around for decades*
. The mod-
ern procedure is essentially a modification of vis-
cocanalostomy, which was first described by Dr.
Stegmann in 1991. Because viscocanalostomy is a
technically difficult surgery to perform, it was not
very popular among most eye surgeons. Howev-
er, with the invention (and FDA approval) of the
iTrack, the impressive results and superior safety
profile of Canaloplasty have convinced a number
of surgeons (myself included) to become adept at
this procedure.
What does“Minimally Invasive” re-
ally mean? Traditional glaucoma surger-
ies (trabeculectomy or shunt surgery) re-
quire the creation of a full-thicknes hole (or fistula)
through the wall of the eye (sclera). This allows
*	 Fyodorov SN, Ioffe DI, Ronkina TI: [Glaucoma sur-
gery—- deep sclerectomy]. Vestn Oftalmol 4:6--10, 1982
fluid to flow from the inside of the front of the
eye (anterior chamber) through the scleral hole to
a bleb (cyst, or blister-like elevation of the con-
junctiva). From here the fluid somehow finds its
way back into the venous system. These surgeries
are called “penetrating.” Canaloplasty, on the oth-
er hand, is a non-penetrating (or “minimally inva-
sive”) surgery because only a partial thickness flap
is created in the sclera. This flap is then sewn back
in place after Schlemm’s canal is opened so there is
no fistula created between the inside and outside of
the eye. Instead, fluid in the eye drains out through
the (newly opened) natural drainage system of the
eye.
How long does Canaloplasty take?
Canaloplasty is not a quick surgery (at least
by eye surgery standards). In order for the
surgery to work properly, your surgeon must make
a flap in the sclera (the white part of the eye) and
extend this all the way to a very thin and fragile
membrane called Descement’s membrane without
tearing it. This flap is created just above a vascu-
lar tissue (which easily bleeds) called the choroid.
All of this happens in a space no larger than the
fingernail on your “pinky” finger. It can be tedi-
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“
ous and requires both skill and patience from your
surgeon. Thus, it can take anywhere between 45
minutes and two hours. The benefits, however, can
last a lifetime.
What if my natural drainage
canal cannot be fully
catheterized? To get the full benefit of
Canaloplasty, it is important for your surgeon to
canulate the full 360 degrees of Schlemm’s canal,
dilate the canal with viscoelastic, and stent it open
with a suture. The inability to complete any one of
these elements (say, from prior scarring of the ca-
nal) can limit the effectiveness of the surgery. How-
ever, even if a full Canaloplasty procedure cannot
be completed, your surgeon can most likely convert
to either a traditional trabeculectomy or viscocana-
lostomy. A recent study**
confirmed that, while not
as effective as Canaloplasty, viscocanalostomy can
significantly reduce the pressure in the eye provid-
ing for some protection from glaucoma.
**	 Canaloplasty in One Eye Compared With Viscoca-
nalostomy in the Contralateral Eye in Patients With Bilateral
Open-angle Glaucoma. Koerber, N. Journal of Glaucoma.
Online ahead of print, January 26, 2011.
Is Canaloplasty surgery painful?
No. During surgery your eye will be anes-
thetized (numbed). After surgery you will
be given drops to reduce inflammation and prevent
pain. Generally, people do notice a “foreign body
sensation” (scratchy sensation) under the upper
eyelid for up to a few weeks after surgery. This is
caused by the slowly dissolving sutures and resolves
on its own. If you have Canaloplasty surgery and
have more severe pain than what is described here,
you should immediately contact your surgeon.
5
If something doesn’t work, then
try something else. Because this
new procedure is un-
believable. I can’t say
enough about it. I’m
just thrilled. It’s like
giving me a new life!
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Canaloplasty
ELIGIBILITY
I’ve had glaucoma laser surgery.
Can I have Canaloplasty? If you have
had either of the laser surgeries for open
angle glaucoma (Argon Laser Trabeculoplasty or
Selective Laser Trabeculoplasty), you may still be
a candidate for Canaloplasty. It depends, however,
on how much scarring there is from the laser sur-
gery. Although your surgeon can visually inspect
the area around Schelmm’s canal using a special
contact lens (a technique called gonioscopy), s/he
cannot tell if there has been permanent scarring
of the canal itself. It may not be possible to fully
catheterize the canal if there is dense scarring of
the canal (called stenosis). In that case, your sur-
geon would not be able to stent the canal open with
a suture, but would still inject a special gel (called a
viscoelastic) into the partially opened canal. When
the canal cannot be fully canulated and the stent
is not placed, this is called viscocanalostomy. Al-
though not as effective as canalopasty, it can still
lower the IOP.
I’ve already had traditional glau-
coma surgery (trabeculectomy).
Can I have Canaloplasty? The stand-
ard answer would be “no.” However, it is possible
(though technically quite challenging) for Canalo-
plasty to be done in an eye that has already had a
trabeculectomy that is no longer functioning. If
you and your surgeon are considering this option it
is important for you to have realistic (guarded) ex-
pectations of success. Many patients are interested
in the option of Canaloplasty because (compared
to other glaucoma surgeries) there are fewer risks.
But, if you are not the ideal candidate, there may
also be less of a potential benefit.
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I’ve used glaucoma drops for a very
long time. Will that affect the suc-
cess of Canaloplasty? Possibly*
. There
is growing evidence that Schelmm’s canal (the eye’s
natural drainage duct) decreases in size with long-
term use of glaucoma medications. If there is
significant stenosis (scarring down) of the canal,
then it may not be possible to thread the catheter
all of the way around the canal. However, even
if a stent cannot be left in the canal it is generally
possible to dilate a significant portion of the canal
with viscoelastic. When the cathether cannot be
fully threaded and a stent is not placed, this proce-
dure is called viscocanalostomy. Viscocanalostomy
has been around since 1991 and is also an effective
treatment for glaucoma (though less so than Cana-
loplasty).
*	 Dahan E, Drusedau MU: Nonpenetrating filtration
surgery for glaucoma: control by surgery only. J Cataract
Refract Surg 26:695--701, 2000
8 Fill out our brief online
evaluation form to see if
you or your loved one is
a candidate for this
exciting new surgery.
Go to http://new-glaucoma-treatments.com/canaloplasty-evaluation/
Visit Online
Evaluation Form
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Will my vision change after
Canaloplasty? If you are hoping for bet-
ter vision after canaloplasty, it is important
to point out that the purpose of any glaucoma treat-
ment (incuding Canaloplasty) is to preserve vision,
not improve it. That being said, your vision will
change in the following ways after surgery. First,
your vision will likely be worse the first few days (or
even weeks) after surgery. This is expected. When
Schlemm’s canal is dilated some blood refluxes
back through the newly dilated canal into the eye.
Some even consider this a sign of successful sur-
gery. This blood eventually is cleared out the same
way it got into the eye. Another cause of (gener-
ally temporary) fluctuations in vision is surgically
induced astigmatism from the suture used to close
the surgical incision. This almost always resolves
by a month or so after surgery Once the eye is fully
Canaloplasty
BENEFITS
9
healed (about three months after surgery) an inter-
esting thing happens: some patients note that their
vision does seem better than it was prior to surgery.
This is likely because glaucoma drops worsen a con-
dition called Tear Dysfunctional Syndrome that can
cause blurred vision. After successful Canaloplasty
surgery the need for glaucoma drops is reduced (or
even eliminated). Without these drops, Tear Dys-
functional Syn-
drome improves
which can
result in
clearer
vision
for some
patients.
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Will Canaloplasty cure my
glaucoma? No. To date there is no
cure for glaucoma. The best any treat-
ment can do is to halt (or slow) the progression of
this disease. The closer the IOP to 8mmHg, the
better (below that and the eye can lose vision from
the pressure being too low). Studies have shown
that for most glaucoma patients an IOP of less than
15mmHg can be protective (a goal often achieved
with Canaloplasty). Some forms of glaucoma (such
as advanced, low tension, or normal tension glau-
coma) require IOPs of less than 12mmHg in order
to avoid loss of vision. Only your eye surgeon can
determine what your eye’s goal should be.
WillIbeabletostopusing glau-
coma drops after Canaloplasty?
Possibly. Remember that the primary
objective of any glaucoma surgery (including Ca-
naloplasty) is to lower your IOP into a safer range
and protect you from further loss of vision. A sec-
ondary goal would be to reduce (or even eliminate)
the use of glaucoma drops. Studies have shown
Canaloplasty to be effective at achieving both of
these goals. Not only do most people who undergo
Canaloplasty have lower IOPs after surgery, but on
average, they are able to stop just under two medi-
cations. What does “just under two” mean? Well,
some people are able to stop one drop, some two,
others none and some are even able to stop all of
their drops. How many you will be able to stop if
you have Canaloplasty cannot be predicted, though
it’s likely that you will be able to stop at least one of
them if you are on multiple drops.
How long will my IOP stay con-
trolled with Canaloplasty? Be-
cause Canaloplasty has only been FDA
approved since 2008, we only have three-year re-
sults**
. There is no reason, however, to believe that
the surgery will “stop working.” In a study that
looked at the long-term (7 year) results of com-
bined cataract surgery and viscocanalostomy(the
less effective precursor to Canaloplasty), IOP was
reduced by over 33% (on average) at the last docu-
**	 Three-year results of circumferential viscodilation
and tensioning of Schlemm canal using a microcatheter to
treat open-angle glaucoma. Richard A. Lewis, Kurt von
Wolff, Manfred Tetz, Norbert Koerber, John R. Kearney,
Bradford J. Shingleton, Thomas W. Samuelson. Journal of
Cataract & Refractive Surgery - April 2011 (Vol. 37, Issue
4, Pages 682-690, DOI: 10.1016/j.jcrs.2010.10.055)
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mented visit.***
We can reasonably expect the long-
term results of Canaloplasty and Phacocanaloplasty
to be even better than those published for viscoca-
nalostomy and Phacoviscocanalostomy.
What if Canaloplasty doesn’t
work? Can I still have tradi-
tional glaucoma surgery after
Canaloplasty? Yes. Having Canaloplasty does
not affect your ability to have other types of glau-
coma surgery at a later date as long as your Cana-
loplasty surgeon operates in one of the superior
“quadrants” of the eye. Some Canaloplasty sur-
geons, however, operate at what is called the 12:00
position. This approach can make it difficult (but
not impossible) for a surgeon to perform tradition-
al glaucoma surgery at a later date.
I’m a very active person.
Will having Canaloplasty force
me to limit my activities?
***	 Seven-year follow-up of combined cataract extrac-
tion and viscocanalostomy. Manijeh S. Wishart, Evgenios
Dagres. Journal of Cataract & Refractive Surgery - De-
cember 2006 (Vol. 32, Issue 12, Pages 2043-2049, DOI:
10.1016/j.jcrs.2006.08.035)
The answer to this question depends on what time,
after surgery, you are referring. Immediately after
surgery (and at least for a few days, but sometimes
up to weeks after) your vision will be blurry in the
eye that had canaloplasty. Therefore, any activities
that require good binocular vision (such as work-
ing with heavy machinery) should be avoided until
the vision improves. Additionally, it is generally a
good idea to keep the eye clean and dry (no garden-
ing or swimming) for at least a few weeks. Once
the incision has healed over (about a month after
surgery) it is generally OK to resume all of your
usual activities.
Contrast this with traditional glacuoma surgery
(trabeculectomy) which does limit your activities
for the rest of your life. Because of the fragile na-
ture of a bleb after trabeculectomy (and the risk of
rupture and/or infec-
tion), once someone
has had trabeculec-
tomy surgery s/he
cannot participate
in most water sports
without high-quality
protective eyewear.
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I wear soft contact lenses. Can I
continue to wear them after
Canaloplasty? Yes, but you may
have to wait until the eye is healed from surgery.
How soon you may restart use of contact lenses
will be up to your surgeon. Additionally, it may be
necessary to get fitted for new contact lenses after
Canaloplasty as the surgery can sometimes change
your refractive error.
Contrast this with traditional glacuoma surgery
(trabeculectomy). Because of the fragile nature of
a bleb after trabeculectomy (and the risk of rup-
ture and/or infection), once someone has had trab-
eculectomy surgery s/he cannot wear soft contact
lenses after surgery for as long as the bleb is func-
tioning. Hard contact lenses, however, are gener-
ally OK to wear even with trabeculectomy (though
a refitting may be needed after surgery).
I’ve heard that Canaloplasty is
not as effective as more tradi-
tional glaucoma surgery
(trabeculectomy). Is this true? No, although
this is widely believed by many surgeons who do
not perform Canaloplasty. It has generally been
thought that trabeculectomy is the only way to
get intraocular pressures (IOPs) under 12mmHg.
However, a recent head-to-head study ****
comparing
one year results of Canaloplasty vs. trabeculectomy
showed no significant difference in average IOP
between the two surgeries. Granted, average IOP
does not address the issue of the lowest IOP achiev-
able. Nevertheless, some of my own patients who
have had Canaloplasty now have pressures between
8-10mmHg. This is by no means the average result,
but does speak to the issue of whether it is possible
for Canaloplasty to lower the IOP below 10mmHg.
Is Canaloplasty really safer than
traditional glaucoma surgery
(trabeculectomy)? Yes. A recent
study*****
compared one year results of Canaloplasty
vs. trabeculectomy. Although there was no significant
difference in the final intraocular pressures (IOPs)
between the two surgeries (meaning both surgeries
were equally good at lowering IOP), two differences
were noted: (1) Canaloplasty patients experienced
fewer side effects and complications compared to
those who had trabeculectomy; and (2) the patients
who had Canaloplasty had better vision than those
patients who had trabeculectomy.
****	 Non-Penetrating Schlemm’s Canaloplasty versusTrab-
eculectomy: A Head-to-Head Comparison. Tam D, Calafati J,
Ahmed I. [Submitted for publication, December 2010].
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RISKS
Canaloplasty
What are
the Risks of
Canaloplasty?
Although it is true that there are
fewer risks with Canaloplasty than
there are with traditional glaucoma
surgery (trabeculectomy), it is not
without risk. All surgeries (there
are no exceptions) have risks associated with them.
The important thing to consider when faced with
the need for surgery is the relative risk of the pro-
cedure compared to going without the procedure.
If your glaucoma is not under control then (given
enough time) you will lose vision. Glaucoma sur-
geries offer a method of preventing that loss of
vision. The most commonly encountered risks of
Canaloplasty are:
1. Bleeding in the eye. Almost 30% of people
who have Canaloplasty have some bleeding in the
front of the eye. However, as mentioned earlier,
this bleeding (called a hyphema or microhyphema)
is pretty much to be expected (and may actually be
desired *
). This resolves with time and rarely causes
any permanent reduction in vision.
2. Intraocular pressure“spikes”during the heal-
ing period after surgery. About 5% (one in twenty)
people will have a short period after surgery when
*	 Canaloplasty and Transient Anterior Chamber
Haemorrhage: a Prognostic Factor? Koch J, Heiligenhaus
A, Heinz C. Klinische Monatsblätter für Augenheilkunde
(Clinical Journal of Ophthalmology) 2010 Nov 16. (online
ahead of print).
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the IOP is actually higher than it was before sur-
gery. This almost always resolves.
3. The formation of a bleb (blister) on the sur-
face of the eye in the area of the incision (6%). It
is worth noting that with trabeculectomy, the for-
mation of a stable bleb is necessary for success,
while with Canaloplasty, it is considered to be an
undesireable outcome, or “risk.” These blebs rare-
ly limit the effectiveness of Canaloplasty. Howev-
er, blebs can be associated with Tear Dysfunctional
Syndrome (Dry Eye Syndrome) and could limit
your ability to participate in certain activities (such
as certain water sports).
4. Descemet’s Membrane Separation, or De-
tachment (3%). In order to open Schlemm’s canal,
a gel-like substance (called a viscoelastic) is injected
into the canal. If the canal is particularly “tight”
it is possible for the gel to follow the path of least
resistance and dissect beneath Descement’s Mem-
brane (the thin film on the back of the cornea). If
this happens, the vision could be affected. How-
ever, with time (weeks to months) these almost al-
ways resolve on their own. If it is not spontane-
ously improving, it is generally possible for your
surgeon to inject a gas bubble in your eye to press
this membrane back against the cornea.
5. The need to perform traditional glaucoma
surgery (4%). Less than one in twenty Canalo-
plasty surgeries “fail” and must be converted to
either trabeculectomy or a “shunt.” This may be
done either at the time of initial surgery or at a
later date. Your surgeon would make this decision
as clinically appropriate.
6. Hypotony (IOP too low). “Too low?” you may
be wondering, “I thought the problem was that
the pressure was too high?” Well, if the IOP drops
below 5mmHg (millimeters of Mercury) and stays
there, vision can be lost from a condition known as
“hypotony maculopathy.” Fortunately, this condi-
tion is pretty rare with Canaloplasty (only one per-
son in 200 would be expected to have prolonged
hypotony). Compare this to trabeculectomy in
which at least 1 out of every 10 people is likely to
experience hypotony.
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7. Infection. To date, vision-threatening infec-
tion of the eye (called “endophthalmitis”) has not
been documented with Canaloplasty. In theory,
however, anytime an incision is made in the eye, an
infection could be possible. So, although the risk
seems to be less than 1 in 1,000, it’s probably not
zero. Compare this to trabeculectomy which car-
ries up to a 5% chance per year of developing an
infection called “blebitis” that (if not caught early
and treated) can result in endophthalmitis and loss
of vision.
In summary, although not without risk, Canalo-
plasty is associated with significantly fewer risks
(both in number and severity) than traditional glau-
coma surgeries such as trabeculectomy
I’m afraid of having something
placed in my eye. What are the
risks of the stent? Although this is
an understandable concern, the only thing left in
the eye after Canaloplasty is a suture. The material
used in this suture (polypropylene) has been used
in eye surgery for decades and has a very good safe-
ty record. In fact, this material has been used in
the eye far longer than most of the materials used
to make the intraocular lenses (IOLs) in modern
cataract surgery. It is very unlikely that this suture
would ever erode into or through the eye wall as it
is securely threaded through Schlemm’s canal. In
the few reported cases where the suture has erod-
ed into the anterior chamber it seldom causes any
problem.
What is the big
deal about a
bleb, anyway?
With traditional glaucoma surgery
(trabeculectomy), a blister-like
fluid collection (called a “bleb”)
must be present on the surface of
the eye for the surgery to work.
Aqueous fluid (the fluid inside the
eye) flows through the fistula into this bleb where it
then finds its way out of the eye. If this bleb scars
down, the the surgery fails and the intraocular pres-
sure (IOP) goes back up potentially causing a fur-
ther loss of vision from glaucoma. Unfortunately,
the body wants to scar down the bleb as part of
the natural healing response. In order to prevent
this from happening most modern trabeculectomy
surgeons use a chemical called an “antimetabolite”
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to preserve the bleb. The most commonly used
antimetabolite (Mitomycin-C, or MMC) causes per-
manent damage to the eye tissue in the area of the
surgery.
The tissue exposed to MMC is very fragile and does
not heal well. Fluid in the bleb exerts pressure
which can result in what is called a “high bleb.”
This is essentially a thin bubble-shaped bleb. These
can cause (or may exacerbate) Tear Dysfunctional
Syndrome resulting in chronic irritation, tearing,
and blurred vision. Because the wall of the bleb is
so thin any trauma to the eye can rupture it. Since
it does not heal well any damage to the bleb may
require surgical revision.
Finally, and most concerning, is that when MMC
is used during trabeculectomy, there is up to a 5%
risk per year of bleb leak**
which can progress to
**	 Greenfield DS, Suñer IJ, Miller MP, Kangas TA,
Palmberg PF, Flynn HW Jr. Endophthalmitis after filtering
surgery with mitomycin. Arch Ophthalmol 1996;114:943-
949.
infection of the inside of the eye (endophthalmitis,
up to 1% per year) if not successfully treated. En-
dophthalmitis often leads to severe loss of vision
or blindness. This risk continues for the life of the
patient unless the bleb scars down (fails).
Canaloplasty is a “blebless” (or bleb-free) pro-
cedure. With Canaloplasty no fistuas are created
and there is no need to modify the natural healing
of the eye. Without a bleb, there is no worsening
of Tear Dysfunctional Syndrome or risk of blebi-
tis. Occasionally (about 6% of the time), a bleb will
spontaneously form with Canaloplasty. However,
because most Canaloplasty surgeons do not use
MMC, the bleb is usually “shallow” and unlikely to
result in Tear Dysfunctional Syndrom or blebitis.
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Surgeons & References
Canaloplasty
Are all Canaloplasty surgeons Glaucoma
Specialists? No. For example, Dr. Richardson is
not fellowship trained but does specialize in treat-
ing glaucoma with advanced procedures such as Canaloplasty. A
“fellowship trained” glaucoma specialist is someone who spends
one to two additional years after residency learning how to deal
with advanced and unusual forms of glaucoma. Because Canalo-
plasty can most effectively treat earlier (less advanced) forms of
the more common types of open angle glaucoma, it is often per-
formed by general ophthalmologists and/or cataract surgeons.
Indeed, it is particularly effective when done at the same time as
cataract surgery - in which case it is called “phacocanaloplasty.”
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What training is required to
become an Interventional
Ophthalmologist
(CanaloplastySurgeon)?Interventional Oph-
thalmologists must first complete their training as
EyeMDs (completion of a bachelor’s degree fol-
lowed by four years of medical school, one year of
internship, and three years of residency training in
eye diseases and surgery). Once proficient as an
eye surgeon, an ophthalmologist can request to be
trained in the technique of Canaloplasty. Doctors
are required to complete a “wet-lab” (practice on
cadaver eyes) prior to performing Canaloplasty sur-
gery on humans. Then, the first 10
surgeries are conducted under the
direct monitoring of a Clinical Spe-
cialist. Only a fraction of surgeons
who start the Canalo-
plasty training complete
the monitoring require-
ments and go on to be-
come Canaloplasty sur-
geons.
Where can I find a
Canaloplasty surgeon
near me? Visit the iScience web-
site*
. This site will provide a list of Canaloplasty
surgeons near you.
How much does Canaloplasty
cost? The amount charged for cana-
loplasty varies by surgeon and surgery
center. If you do not have insurance, the total cost
for canaloplasty can range from $4,000 to upwards
of $8,000 per eye. Fortunately, Medicare and many
insurances pay for Canaloplasty when surgical treat-
ment of glaucoma is indicated. Even if you do not
have insurance, however, Canaloplasty can pay for
itself over time simply by saving you thousands of
dollars per year in the cost of glaucoma drops that
may no longer be necessary after this surgery.
*	 http://canaloplasty.com/iscience/find_a_physician.php
22 23
24
1
5
10
15
21
Last
© 2013 New-Glaucoma-Treatments.com
Where can I learn more about Canaloplasty?
Below are some additional resources that could help you to decide if Canaloplasty is right for
you:
1. Canaloplasty.com - Created by iScience, the manufacturer of the catheter used in Cana-
loplasty. This is where you would go to find a Canaloplasty surgeon near you.
	
2. YouTube.com - If you want to see what this surgery actually looks like (and aren’t too
squeamish).
3. New-Glaucoma-Treatments.com - This website was created by Dr. Richardson in order
to provide a ‘one stop solution’ for those patients looking for the latest information about Ca-
naloplasty. Dr. Richardson updates this site weekly with the latest news about this and other
glaucoma treatments.
4. Find a Canaloplasty sur-
geon and schedule a consul-
tation - There is no better way
to find out if Canaloplasty is
right for you than to have your
eye evaluated by a surgeon cer-
tified to perform Canaloplasty.
25
Go to http://new-glaucoma-treatments.com/canaloplasty-evaluation/
Fill out our brief online
evaluation form to see if
you or your loved one is
a candidate for this
exciting new surgery.
Visit Online
Evaluation Form
Dr. David Richardson has performed thousands of eye surgeries using the most advanced techniques. He is trusted not only
by thousands of patients, but also by other medical professionals. Dr. Richardson was named a “Super Doctor” by his peers in the
Los Angeles Magazine in 2010, 2011, 2012 and 2013. In a similar survey conducted by Pasadena Magazine, Dr. Richardson was
also voted as a “Top Doc” for the past 6 consecutive years (2008-2013). Actions, though, speak louder than words - Dr. Richard-
son is the personal eye surgeon for many of the most respected doctors in the San Gabriel valley. Dr. David Richardson is among
a select group of ophthalmologists in Southern California offering Canaloplasty as a treatment option for his glaucoma patients.
Do you want to receive other patient-focused materials regarding glaucoma or cataract? Visit -> drmd.me/newsletter-pdf
experience the Dr. Richardson difference...
Impeccable Personalized Care
Newsletter
Sign-up

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Canaloplasty Surgery FAQ by Dr. David Richardson

  • 2. 1 5 10 15 21 Last © 2013 New-Glaucoma-Treatments.com Canaloplasty (pronounced Kah-NAL-oh-plas-tee) is a new glaucoma treatment that gives many people with this potentially blinding condition the hope of saving the vision they have. Canaloplasty can re- duce pressure in the eye (IOP) by nearly 40%, and many glaucoma patients who have had Canaloplasty no longer need medications. This “minimally inva- sive” procedure is available alone or can be done with cataract extraction (phacocanaloplasty). It is a “non-penetrating” surgical procedure that does not require creation of a fistula nor result in a “bleb” such as with traditional trabeculectomy surgery. In- sertion of a micro-catheter into Schlemm’s canal (the eye’s internal drainage duct) facilitates exit of eye fluid through the natural outflow. The canal is then dilated by injecting a sterile, gel-like material called a viscoelastic. After the drainage channel is made larger the micro-catheter is removed and a Canaloplasty Surgery FAQ suture is placed within the canal system. Suture ten- sion within this system keeps it open for years re- sulting in a controlled eye pressure. What is Canaloplasty? CANALOPLASTY New GlaucomaTreatment Go to http://new-glaucoma-treatments.com/canaloplasty/ See how Canaloplasty is done. Watch Dr. Richardson’s video online
  • 3. 1 5 10 15 21 Last © 2013 New-Glaucoma-Treatments.com Safety. Canaloplasty is safer than traditional glau- coma surgery (trabeculectomy). If you are consid- ering glaucoma surgery to prevent further vision loss then choosing a surgery that has fewer risks makes sense. Age. Younger patients need a better option than traditional glaucoma surgery. Traditional glaucoma surgery is less likely to succeed in younger patients and carries a lifetime risk of infection. Success with Canaloplasty is not age dependent and there is no lifetime risk of infection. Active Lifestyle. If you are an energetic person who enjoys such activities as watersports, it is im- portant for you to know that having traditional Why Canaloplasty?
  • 4. 1 5 10 15 21 Last © 2013 New-Glaucoma-Treatments.com glaucoma surgery will severely limit your ability to participate in certain sports. No such limitation ex- ists with Canaloplasty. Once healed, patients who have had Canaloplasty are able to return to their previous active lifestyles without restriction or lim- itation. Nearsighted. People who are very nearsighted (highly myopic) are at a much higher risk of vision- threatening complications from traditional glauco- ma surgeries. This is not true with Canaloplasty. Ethnicity. Traditional glaucoma surgery has a high failure rate among African American patients. In contrast, Canaloplasty has a well-established track record of success among many races. Fear of Cataract. If you do not currently have a cataract, you should know that the risk of devel- oping one increases substantially after traditional glaucoma surgery. This risk is much lower with Canaloplasty. Difficulty with Glaucoma Medications. If you are having trouble tolerating or affording your glaucoma medications, then Canaloplasty may be an option for you. With traditional glaucoma surgeries, the risk is just too high to consider for reasons of financial hardship or side effects of medicines alone. These are just some of the many reasons to con- sider Canaloplasty. If you have open angle glau- coma (the most common type) and are considering glaucoma surgery, then you should explore your available options before making a decision. Al- though there are certainly instances where tradi- tional glaucoma surgery is the best (or even only ) option available, most patients with glaucoma are candidates for Canaloplasty and should consider this safer option.
  • 5. 1 5 10 15 21 Last © 2013 New-Glaucoma-Treatments.com How long has Canaloplasty been around? The answer to this question is not as straightforward as it might seem. Al- though the iTrack catheter (required to perform canaloplasty) has only been FDA approved since 2008, the surgical technique used to perform Ca- naloplasty has been around for decades* . The mod- ern procedure is essentially a modification of vis- cocanalostomy, which was first described by Dr. Stegmann in 1991. Because viscocanalostomy is a technically difficult surgery to perform, it was not very popular among most eye surgeons. Howev- er, with the invention (and FDA approval) of the iTrack, the impressive results and superior safety profile of Canaloplasty have convinced a number of surgeons (myself included) to become adept at this procedure. What does“Minimally Invasive” re- ally mean? Traditional glaucoma surger- ies (trabeculectomy or shunt surgery) re- quire the creation of a full-thicknes hole (or fistula) through the wall of the eye (sclera). This allows * Fyodorov SN, Ioffe DI, Ronkina TI: [Glaucoma sur- gery—- deep sclerectomy]. Vestn Oftalmol 4:6--10, 1982 fluid to flow from the inside of the front of the eye (anterior chamber) through the scleral hole to a bleb (cyst, or blister-like elevation of the con- junctiva). From here the fluid somehow finds its way back into the venous system. These surgeries are called “penetrating.” Canaloplasty, on the oth- er hand, is a non-penetrating (or “minimally inva- sive”) surgery because only a partial thickness flap is created in the sclera. This flap is then sewn back in place after Schlemm’s canal is opened so there is no fistula created between the inside and outside of the eye. Instead, fluid in the eye drains out through the (newly opened) natural drainage system of the eye. How long does Canaloplasty take? Canaloplasty is not a quick surgery (at least by eye surgery standards). In order for the surgery to work properly, your surgeon must make a flap in the sclera (the white part of the eye) and extend this all the way to a very thin and fragile membrane called Descement’s membrane without tearing it. This flap is created just above a vascu- lar tissue (which easily bleeds) called the choroid. All of this happens in a space no larger than the fingernail on your “pinky” finger. It can be tedi- 1 2 3
  • 6. 1 5 10 15 21 Last © 2013 New-Glaucoma-Treatments.com “ ous and requires both skill and patience from your surgeon. Thus, it can take anywhere between 45 minutes and two hours. The benefits, however, can last a lifetime. What if my natural drainage canal cannot be fully catheterized? To get the full benefit of Canaloplasty, it is important for your surgeon to canulate the full 360 degrees of Schlemm’s canal, dilate the canal with viscoelastic, and stent it open with a suture. The inability to complete any one of these elements (say, from prior scarring of the ca- nal) can limit the effectiveness of the surgery. How- ever, even if a full Canaloplasty procedure cannot be completed, your surgeon can most likely convert to either a traditional trabeculectomy or viscocana- lostomy. A recent study** confirmed that, while not as effective as Canaloplasty, viscocanalostomy can significantly reduce the pressure in the eye provid- ing for some protection from glaucoma. ** Canaloplasty in One Eye Compared With Viscoca- nalostomy in the Contralateral Eye in Patients With Bilateral Open-angle Glaucoma. Koerber, N. Journal of Glaucoma. Online ahead of print, January 26, 2011. Is Canaloplasty surgery painful? No. During surgery your eye will be anes- thetized (numbed). After surgery you will be given drops to reduce inflammation and prevent pain. Generally, people do notice a “foreign body sensation” (scratchy sensation) under the upper eyelid for up to a few weeks after surgery. This is caused by the slowly dissolving sutures and resolves on its own. If you have Canaloplasty surgery and have more severe pain than what is described here, you should immediately contact your surgeon. 5 If something doesn’t work, then try something else. Because this new procedure is un- believable. I can’t say enough about it. I’m just thrilled. It’s like giving me a new life! 4
  • 7. 1 5 10 15 21 Last © 2013 New-Glaucoma-Treatments.com Canaloplasty ELIGIBILITY I’ve had glaucoma laser surgery. Can I have Canaloplasty? If you have had either of the laser surgeries for open angle glaucoma (Argon Laser Trabeculoplasty or Selective Laser Trabeculoplasty), you may still be a candidate for Canaloplasty. It depends, however, on how much scarring there is from the laser sur- gery. Although your surgeon can visually inspect the area around Schelmm’s canal using a special contact lens (a technique called gonioscopy), s/he cannot tell if there has been permanent scarring of the canal itself. It may not be possible to fully catheterize the canal if there is dense scarring of the canal (called stenosis). In that case, your sur- geon would not be able to stent the canal open with a suture, but would still inject a special gel (called a viscoelastic) into the partially opened canal. When the canal cannot be fully canulated and the stent is not placed, this is called viscocanalostomy. Al- though not as effective as canalopasty, it can still lower the IOP. I’ve already had traditional glau- coma surgery (trabeculectomy). Can I have Canaloplasty? The stand- ard answer would be “no.” However, it is possible (though technically quite challenging) for Canalo- plasty to be done in an eye that has already had a trabeculectomy that is no longer functioning. If you and your surgeon are considering this option it is important for you to have realistic (guarded) ex- pectations of success. Many patients are interested in the option of Canaloplasty because (compared to other glaucoma surgeries) there are fewer risks. But, if you are not the ideal candidate, there may also be less of a potential benefit. 6 7
  • 8. 1 5 10 15 21 Last © 2013 New-Glaucoma-Treatments.com I’ve used glaucoma drops for a very long time. Will that affect the suc- cess of Canaloplasty? Possibly* . There is growing evidence that Schelmm’s canal (the eye’s natural drainage duct) decreases in size with long- term use of glaucoma medications. If there is significant stenosis (scarring down) of the canal, then it may not be possible to thread the catheter all of the way around the canal. However, even if a stent cannot be left in the canal it is generally possible to dilate a significant portion of the canal with viscoelastic. When the cathether cannot be fully threaded and a stent is not placed, this proce- dure is called viscocanalostomy. Viscocanalostomy has been around since 1991 and is also an effective treatment for glaucoma (though less so than Cana- loplasty). * Dahan E, Drusedau MU: Nonpenetrating filtration surgery for glaucoma: control by surgery only. J Cataract Refract Surg 26:695--701, 2000 8 Fill out our brief online evaluation form to see if you or your loved one is a candidate for this exciting new surgery. Go to http://new-glaucoma-treatments.com/canaloplasty-evaluation/ Visit Online Evaluation Form
  • 9. 1 5 10 15 21 Last © 2013 New-Glaucoma-Treatments.com Will my vision change after Canaloplasty? If you are hoping for bet- ter vision after canaloplasty, it is important to point out that the purpose of any glaucoma treat- ment (incuding Canaloplasty) is to preserve vision, not improve it. That being said, your vision will change in the following ways after surgery. First, your vision will likely be worse the first few days (or even weeks) after surgery. This is expected. When Schlemm’s canal is dilated some blood refluxes back through the newly dilated canal into the eye. Some even consider this a sign of successful sur- gery. This blood eventually is cleared out the same way it got into the eye. Another cause of (gener- ally temporary) fluctuations in vision is surgically induced astigmatism from the suture used to close the surgical incision. This almost always resolves by a month or so after surgery Once the eye is fully Canaloplasty BENEFITS 9 healed (about three months after surgery) an inter- esting thing happens: some patients note that their vision does seem better than it was prior to surgery. This is likely because glaucoma drops worsen a con- dition called Tear Dysfunctional Syndrome that can cause blurred vision. After successful Canaloplasty surgery the need for glaucoma drops is reduced (or even eliminated). Without these drops, Tear Dys- functional Syn- drome improves which can result in clearer vision for some patients.
  • 10. 1 5 10 15 21 Last © 2013 New-Glaucoma-Treatments.com Will Canaloplasty cure my glaucoma? No. To date there is no cure for glaucoma. The best any treat- ment can do is to halt (or slow) the progression of this disease. The closer the IOP to 8mmHg, the better (below that and the eye can lose vision from the pressure being too low). Studies have shown that for most glaucoma patients an IOP of less than 15mmHg can be protective (a goal often achieved with Canaloplasty). Some forms of glaucoma (such as advanced, low tension, or normal tension glau- coma) require IOPs of less than 12mmHg in order to avoid loss of vision. Only your eye surgeon can determine what your eye’s goal should be. WillIbeabletostopusing glau- coma drops after Canaloplasty? Possibly. Remember that the primary objective of any glaucoma surgery (including Ca- naloplasty) is to lower your IOP into a safer range and protect you from further loss of vision. A sec- ondary goal would be to reduce (or even eliminate) the use of glaucoma drops. Studies have shown Canaloplasty to be effective at achieving both of these goals. Not only do most people who undergo Canaloplasty have lower IOPs after surgery, but on average, they are able to stop just under two medi- cations. What does “just under two” mean? Well, some people are able to stop one drop, some two, others none and some are even able to stop all of their drops. How many you will be able to stop if you have Canaloplasty cannot be predicted, though it’s likely that you will be able to stop at least one of them if you are on multiple drops. How long will my IOP stay con- trolled with Canaloplasty? Be- cause Canaloplasty has only been FDA approved since 2008, we only have three-year re- sults** . There is no reason, however, to believe that the surgery will “stop working.” In a study that looked at the long-term (7 year) results of com- bined cataract surgery and viscocanalostomy(the less effective precursor to Canaloplasty), IOP was reduced by over 33% (on average) at the last docu- ** Three-year results of circumferential viscodilation and tensioning of Schlemm canal using a microcatheter to treat open-angle glaucoma. Richard A. Lewis, Kurt von Wolff, Manfred Tetz, Norbert Koerber, John R. Kearney, Bradford J. Shingleton, Thomas W. Samuelson. Journal of Cataract & Refractive Surgery - April 2011 (Vol. 37, Issue 4, Pages 682-690, DOI: 10.1016/j.jcrs.2010.10.055) 11 12 10
  • 11. 1 5 10 15 21 Last © 2013 New-Glaucoma-Treatments.com mented visit.*** We can reasonably expect the long- term results of Canaloplasty and Phacocanaloplasty to be even better than those published for viscoca- nalostomy and Phacoviscocanalostomy. What if Canaloplasty doesn’t work? Can I still have tradi- tional glaucoma surgery after Canaloplasty? Yes. Having Canaloplasty does not affect your ability to have other types of glau- coma surgery at a later date as long as your Cana- loplasty surgeon operates in one of the superior “quadrants” of the eye. Some Canaloplasty sur- geons, however, operate at what is called the 12:00 position. This approach can make it difficult (but not impossible) for a surgeon to perform tradition- al glaucoma surgery at a later date. I’m a very active person. Will having Canaloplasty force me to limit my activities? *** Seven-year follow-up of combined cataract extrac- tion and viscocanalostomy. Manijeh S. Wishart, Evgenios Dagres. Journal of Cataract & Refractive Surgery - De- cember 2006 (Vol. 32, Issue 12, Pages 2043-2049, DOI: 10.1016/j.jcrs.2006.08.035) The answer to this question depends on what time, after surgery, you are referring. Immediately after surgery (and at least for a few days, but sometimes up to weeks after) your vision will be blurry in the eye that had canaloplasty. Therefore, any activities that require good binocular vision (such as work- ing with heavy machinery) should be avoided until the vision improves. Additionally, it is generally a good idea to keep the eye clean and dry (no garden- ing or swimming) for at least a few weeks. Once the incision has healed over (about a month after surgery) it is generally OK to resume all of your usual activities. Contrast this with traditional glacuoma surgery (trabeculectomy) which does limit your activities for the rest of your life. Because of the fragile na- ture of a bleb after trabeculectomy (and the risk of rupture and/or infec- tion), once someone has had trabeculec- tomy surgery s/he cannot participate in most water sports without high-quality protective eyewear. 13 14
  • 12. 1 5 10 15 21 Last © 2013 New-Glaucoma-Treatments.com I wear soft contact lenses. Can I continue to wear them after Canaloplasty? Yes, but you may have to wait until the eye is healed from surgery. How soon you may restart use of contact lenses will be up to your surgeon. Additionally, it may be necessary to get fitted for new contact lenses after Canaloplasty as the surgery can sometimes change your refractive error. Contrast this with traditional glacuoma surgery (trabeculectomy). Because of the fragile nature of a bleb after trabeculectomy (and the risk of rup- ture and/or infection), once someone has had trab- eculectomy surgery s/he cannot wear soft contact lenses after surgery for as long as the bleb is func- tioning. Hard contact lenses, however, are gener- ally OK to wear even with trabeculectomy (though a refitting may be needed after surgery). I’ve heard that Canaloplasty is not as effective as more tradi- tional glaucoma surgery (trabeculectomy). Is this true? No, although this is widely believed by many surgeons who do not perform Canaloplasty. It has generally been thought that trabeculectomy is the only way to get intraocular pressures (IOPs) under 12mmHg. However, a recent head-to-head study **** comparing one year results of Canaloplasty vs. trabeculectomy showed no significant difference in average IOP between the two surgeries. Granted, average IOP does not address the issue of the lowest IOP achiev- able. Nevertheless, some of my own patients who have had Canaloplasty now have pressures between 8-10mmHg. This is by no means the average result, but does speak to the issue of whether it is possible for Canaloplasty to lower the IOP below 10mmHg. Is Canaloplasty really safer than traditional glaucoma surgery (trabeculectomy)? Yes. A recent study***** compared one year results of Canaloplasty vs. trabeculectomy. Although there was no significant difference in the final intraocular pressures (IOPs) between the two surgeries (meaning both surgeries were equally good at lowering IOP), two differences were noted: (1) Canaloplasty patients experienced fewer side effects and complications compared to those who had trabeculectomy; and (2) the patients who had Canaloplasty had better vision than those patients who had trabeculectomy. **** Non-Penetrating Schlemm’s Canaloplasty versusTrab- eculectomy: A Head-to-Head Comparison. Tam D, Calafati J, Ahmed I. [Submitted for publication, December 2010]. 15 16 17
  • 13. 1 5 10 15 21 Last © 2013 New-Glaucoma-Treatments.com RISKS Canaloplasty What are the Risks of Canaloplasty? Although it is true that there are fewer risks with Canaloplasty than there are with traditional glaucoma surgery (trabeculectomy), it is not without risk. All surgeries (there are no exceptions) have risks associated with them. The important thing to consider when faced with the need for surgery is the relative risk of the pro- cedure compared to going without the procedure. If your glaucoma is not under control then (given enough time) you will lose vision. Glaucoma sur- geries offer a method of preventing that loss of vision. The most commonly encountered risks of Canaloplasty are: 1. Bleeding in the eye. Almost 30% of people who have Canaloplasty have some bleeding in the front of the eye. However, as mentioned earlier, this bleeding (called a hyphema or microhyphema) is pretty much to be expected (and may actually be desired * ). This resolves with time and rarely causes any permanent reduction in vision. 2. Intraocular pressure“spikes”during the heal- ing period after surgery. About 5% (one in twenty) people will have a short period after surgery when * Canaloplasty and Transient Anterior Chamber Haemorrhage: a Prognostic Factor? Koch J, Heiligenhaus A, Heinz C. Klinische Monatsblätter für Augenheilkunde (Clinical Journal of Ophthalmology) 2010 Nov 16. (online ahead of print). 18
  • 14. 1 5 10 15 21 Last © 2013 New-Glaucoma-Treatments.com the IOP is actually higher than it was before sur- gery. This almost always resolves. 3. The formation of a bleb (blister) on the sur- face of the eye in the area of the incision (6%). It is worth noting that with trabeculectomy, the for- mation of a stable bleb is necessary for success, while with Canaloplasty, it is considered to be an undesireable outcome, or “risk.” These blebs rare- ly limit the effectiveness of Canaloplasty. Howev- er, blebs can be associated with Tear Dysfunctional Syndrome (Dry Eye Syndrome) and could limit your ability to participate in certain activities (such as certain water sports). 4. Descemet’s Membrane Separation, or De- tachment (3%). In order to open Schlemm’s canal, a gel-like substance (called a viscoelastic) is injected into the canal. If the canal is particularly “tight” it is possible for the gel to follow the path of least resistance and dissect beneath Descement’s Mem- brane (the thin film on the back of the cornea). If this happens, the vision could be affected. How- ever, with time (weeks to months) these almost al- ways resolve on their own. If it is not spontane- ously improving, it is generally possible for your surgeon to inject a gas bubble in your eye to press this membrane back against the cornea. 5. The need to perform traditional glaucoma surgery (4%). Less than one in twenty Canalo- plasty surgeries “fail” and must be converted to either trabeculectomy or a “shunt.” This may be done either at the time of initial surgery or at a later date. Your surgeon would make this decision as clinically appropriate. 6. Hypotony (IOP too low). “Too low?” you may be wondering, “I thought the problem was that the pressure was too high?” Well, if the IOP drops below 5mmHg (millimeters of Mercury) and stays there, vision can be lost from a condition known as “hypotony maculopathy.” Fortunately, this condi- tion is pretty rare with Canaloplasty (only one per- son in 200 would be expected to have prolonged hypotony). Compare this to trabeculectomy in which at least 1 out of every 10 people is likely to experience hypotony.
  • 15. 1 5 10 15 21 Last © 2013 New-Glaucoma-Treatments.com 7. Infection. To date, vision-threatening infec- tion of the eye (called “endophthalmitis”) has not been documented with Canaloplasty. In theory, however, anytime an incision is made in the eye, an infection could be possible. So, although the risk seems to be less than 1 in 1,000, it’s probably not zero. Compare this to trabeculectomy which car- ries up to a 5% chance per year of developing an infection called “blebitis” that (if not caught early and treated) can result in endophthalmitis and loss of vision. In summary, although not without risk, Canalo- plasty is associated with significantly fewer risks (both in number and severity) than traditional glau- coma surgeries such as trabeculectomy I’m afraid of having something placed in my eye. What are the risks of the stent? Although this is an understandable concern, the only thing left in the eye after Canaloplasty is a suture. The material used in this suture (polypropylene) has been used in eye surgery for decades and has a very good safe- ty record. In fact, this material has been used in the eye far longer than most of the materials used to make the intraocular lenses (IOLs) in modern cataract surgery. It is very unlikely that this suture would ever erode into or through the eye wall as it is securely threaded through Schlemm’s canal. In the few reported cases where the suture has erod- ed into the anterior chamber it seldom causes any problem. What is the big deal about a bleb, anyway? With traditional glaucoma surgery (trabeculectomy), a blister-like fluid collection (called a “bleb”) must be present on the surface of the eye for the surgery to work. Aqueous fluid (the fluid inside the eye) flows through the fistula into this bleb where it then finds its way out of the eye. If this bleb scars down, the the surgery fails and the intraocular pres- sure (IOP) goes back up potentially causing a fur- ther loss of vision from glaucoma. Unfortunately, the body wants to scar down the bleb as part of the natural healing response. In order to prevent this from happening most modern trabeculectomy surgeons use a chemical called an “antimetabolite” 19 20
  • 16. 1 5 10 15 21 Last © 2013 New-Glaucoma-Treatments.com to preserve the bleb. The most commonly used antimetabolite (Mitomycin-C, or MMC) causes per- manent damage to the eye tissue in the area of the surgery. The tissue exposed to MMC is very fragile and does not heal well. Fluid in the bleb exerts pressure which can result in what is called a “high bleb.” This is essentially a thin bubble-shaped bleb. These can cause (or may exacerbate) Tear Dysfunctional Syndrome resulting in chronic irritation, tearing, and blurred vision. Because the wall of the bleb is so thin any trauma to the eye can rupture it. Since it does not heal well any damage to the bleb may require surgical revision. Finally, and most concerning, is that when MMC is used during trabeculectomy, there is up to a 5% risk per year of bleb leak** which can progress to ** Greenfield DS, Suñer IJ, Miller MP, Kangas TA, Palmberg PF, Flynn HW Jr. Endophthalmitis after filtering surgery with mitomycin. Arch Ophthalmol 1996;114:943- 949. infection of the inside of the eye (endophthalmitis, up to 1% per year) if not successfully treated. En- dophthalmitis often leads to severe loss of vision or blindness. This risk continues for the life of the patient unless the bleb scars down (fails). Canaloplasty is a “blebless” (or bleb-free) pro- cedure. With Canaloplasty no fistuas are created and there is no need to modify the natural healing of the eye. Without a bleb, there is no worsening of Tear Dysfunctional Syndrome or risk of blebi- tis. Occasionally (about 6% of the time), a bleb will spontaneously form with Canaloplasty. However, because most Canaloplasty surgeons do not use MMC, the bleb is usually “shallow” and unlikely to result in Tear Dysfunctional Syndrom or blebitis.
  • 17. 1 5 10 15 21 Last © 2013 New-Glaucoma-Treatments.com Surgeons & References Canaloplasty Are all Canaloplasty surgeons Glaucoma Specialists? No. For example, Dr. Richardson is not fellowship trained but does specialize in treat- ing glaucoma with advanced procedures such as Canaloplasty. A “fellowship trained” glaucoma specialist is someone who spends one to two additional years after residency learning how to deal with advanced and unusual forms of glaucoma. Because Canalo- plasty can most effectively treat earlier (less advanced) forms of the more common types of open angle glaucoma, it is often per- formed by general ophthalmologists and/or cataract surgeons. Indeed, it is particularly effective when done at the same time as cataract surgery - in which case it is called “phacocanaloplasty.” 21
  • 18. 1 5 10 15 21 Last © 2013 New-Glaucoma-Treatments.com What training is required to become an Interventional Ophthalmologist (CanaloplastySurgeon)?Interventional Oph- thalmologists must first complete their training as EyeMDs (completion of a bachelor’s degree fol- lowed by four years of medical school, one year of internship, and three years of residency training in eye diseases and surgery). Once proficient as an eye surgeon, an ophthalmologist can request to be trained in the technique of Canaloplasty. Doctors are required to complete a “wet-lab” (practice on cadaver eyes) prior to performing Canaloplasty sur- gery on humans. Then, the first 10 surgeries are conducted under the direct monitoring of a Clinical Spe- cialist. Only a fraction of surgeons who start the Canalo- plasty training complete the monitoring require- ments and go on to be- come Canaloplasty sur- geons. Where can I find a Canaloplasty surgeon near me? Visit the iScience web- site* . This site will provide a list of Canaloplasty surgeons near you. How much does Canaloplasty cost? The amount charged for cana- loplasty varies by surgeon and surgery center. If you do not have insurance, the total cost for canaloplasty can range from $4,000 to upwards of $8,000 per eye. Fortunately, Medicare and many insurances pay for Canaloplasty when surgical treat- ment of glaucoma is indicated. Even if you do not have insurance, however, Canaloplasty can pay for itself over time simply by saving you thousands of dollars per year in the cost of glaucoma drops that may no longer be necessary after this surgery. * http://canaloplasty.com/iscience/find_a_physician.php 22 23 24
  • 19. 1 5 10 15 21 Last © 2013 New-Glaucoma-Treatments.com Where can I learn more about Canaloplasty? Below are some additional resources that could help you to decide if Canaloplasty is right for you: 1. Canaloplasty.com - Created by iScience, the manufacturer of the catheter used in Cana- loplasty. This is where you would go to find a Canaloplasty surgeon near you. 2. YouTube.com - If you want to see what this surgery actually looks like (and aren’t too squeamish). 3. New-Glaucoma-Treatments.com - This website was created by Dr. Richardson in order to provide a ‘one stop solution’ for those patients looking for the latest information about Ca- naloplasty. Dr. Richardson updates this site weekly with the latest news about this and other glaucoma treatments. 4. Find a Canaloplasty sur- geon and schedule a consul- tation - There is no better way to find out if Canaloplasty is right for you than to have your eye evaluated by a surgeon cer- tified to perform Canaloplasty. 25 Go to http://new-glaucoma-treatments.com/canaloplasty-evaluation/ Fill out our brief online evaluation form to see if you or your loved one is a candidate for this exciting new surgery. Visit Online Evaluation Form
  • 20. Dr. David Richardson has performed thousands of eye surgeries using the most advanced techniques. He is trusted not only by thousands of patients, but also by other medical professionals. Dr. Richardson was named a “Super Doctor” by his peers in the Los Angeles Magazine in 2010, 2011, 2012 and 2013. In a similar survey conducted by Pasadena Magazine, Dr. Richardson was also voted as a “Top Doc” for the past 6 consecutive years (2008-2013). Actions, though, speak louder than words - Dr. Richard- son is the personal eye surgeon for many of the most respected doctors in the San Gabriel valley. Dr. David Richardson is among a select group of ophthalmologists in Southern California offering Canaloplasty as a treatment option for his glaucoma patients. Do you want to receive other patient-focused materials regarding glaucoma or cataract? Visit -> drmd.me/newsletter-pdf experience the Dr. Richardson difference... Impeccable Personalized Care Newsletter Sign-up