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ProfessorYuka Itokawa , ProfessorYeunhwa GU  Prepared by: Japan Suzuka University of  Medical Science   30P1-am238 Register #
Research Background ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Methods 2 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Methods 3 ,[object Object],[object Object],[object Object],[object Object],[object Object]
Antioxidation assay ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Methods 4 (Anti-cancer effect) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Methods 5 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Methods 6 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
SOD-like activity (after 15th) This histograph is the image of SOD ( 15days later ) . Each  histograph represents the mean value ±SE.  SOD-like activity (after 15th)
SOD-like activity (after 30th) This histograph is the image of SOD ( 30days later ) .Each histograph represents the mean value ±SE. Analyzed by Dunett-test SOD-like activity (after 30th) *
leukocytes This change in number of leukocytes the blood took from the tail vein ICR mice. Each line gram represents the mean value ±SE. Analyzed by Fisher-test. *p<0.05,**p<0.01 vs control. (↑ 2Gy  whole body irradiation ) *  ** ** ** *  *  *  *  *  *  Gu Lab
This change in number of  l ymphocyte the blood took from the tail vein ICR mice. Each line gram represents the mean value ±SE. Analyzed by Fisher-test. *p<0.05,**p<0.01 vs control  (↑ 2Gy whole body irradiation ) *  *  *  *  *  *  l ymphocyte Gu Lab
Effect on anti-tumor by the sample medication. Each line represents the mean value ±S.E  Analyzed by Dunnett-test. *  *  *  *  *  *  *  *  *  *  *  *  *  *  *  *  *  *  *  *  *  *  *  *  *  *  Tumor volume (non-irradiation group) *  *  *  *  *  *  *  *  *  *  *  *  *  *  *  *  *
Weight of tumor. Each line represents the mean value ±S.E. Analyzed by Dunett-test (n=7) Gu Lab Tumor weight (non-irradiation group)
Weight of tumor. Each line represents the mean value ±S.E.  It was analyzed by Dunett-test (n=7) Gu Lab Tumor weight (irradiation group)
The free radical removal by SOD O2 O2  - An injury factor C H O DAN polymerase SH A replication of DNA error Chromosomal anomalies Approval of autoimmune disease An auto-immunity antigen A - antibody complex Bacteria A virus XOD blood cells, a macrophageWhite  Stimulation We remove to SOD Deactivation
Reinforcement of removal + biophylaxis ability of a cause tumor inhibition mechanism Free radical elimination / antioxidation action The conduction that detoxication / Radhi Cal elimination is enzymatic Anti-inflammatory action DNA disorder (mutation) DNA restoration A mutation cell Cytostasis / apotosis conduction A cancer cell
Structure of tumor immunity by antigen-antibody reaction Natural killer cell Antigen fault acquired immunity Activation Natural killer cell A cancer cell An antibody An antibody-producing cell A killer cell T-helper cells B cell Antigen presentation A macrophage Antigen presenting cells Antigen acquired immunity A carcinoma antigen

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The Immune System, Anticancer Mechanism , Enzyme

  • 1. ProfessorYuka Itokawa , ProfessorYeunhwa GU Prepared by: Japan Suzuka University of Medical Science 30P1-am238 Register #
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  • 9. SOD-like activity (after 15th) This histograph is the image of SOD ( 15days later ) . Each histograph represents the mean value ±SE. SOD-like activity (after 15th)
  • 10. SOD-like activity (after 30th) This histograph is the image of SOD ( 30days later ) .Each histograph represents the mean value ±SE. Analyzed by Dunett-test SOD-like activity (after 30th) *
  • 11. leukocytes This change in number of leukocytes the blood took from the tail vein ICR mice. Each line gram represents the mean value ±SE. Analyzed by Fisher-test. *p<0.05,**p<0.01 vs control. (↑ 2Gy whole body irradiation ) * ** ** ** * * * * * * Gu Lab
  • 12. This change in number of l ymphocyte the blood took from the tail vein ICR mice. Each line gram represents the mean value ±SE. Analyzed by Fisher-test. *p<0.05,**p<0.01 vs control (↑ 2Gy whole body irradiation ) * * * * * * l ymphocyte Gu Lab
  • 13. Effect on anti-tumor by the sample medication. Each line represents the mean value ±S.E Analyzed by Dunnett-test. * * * * * * * * * * * * * * * * * * * * * * * * * * Tumor volume (non-irradiation group) * * * * * * * * * * * * * * * * *
  • 14. Weight of tumor. Each line represents the mean value ±S.E. Analyzed by Dunett-test (n=7) Gu Lab Tumor weight (non-irradiation group)
  • 15. Weight of tumor. Each line represents the mean value ±S.E. It was analyzed by Dunett-test (n=7) Gu Lab Tumor weight (irradiation group)
  • 16. The free radical removal by SOD O2 O2 - An injury factor C H O DAN polymerase SH A replication of DNA error Chromosomal anomalies Approval of autoimmune disease An auto-immunity antigen A - antibody complex Bacteria A virus XOD blood cells, a macrophageWhite Stimulation We remove to SOD Deactivation
  • 17. Reinforcement of removal + biophylaxis ability of a cause tumor inhibition mechanism Free radical elimination / antioxidation action The conduction that detoxication / Radhi Cal elimination is enzymatic Anti-inflammatory action DNA disorder (mutation) DNA restoration A mutation cell Cytostasis / apotosis conduction A cancer cell
  • 18. Structure of tumor immunity by antigen-antibody reaction Natural killer cell Antigen fault acquired immunity Activation Natural killer cell A cancer cell An antibody An antibody-producing cell A killer cell T-helper cells B cell Antigen presentation A macrophage Antigen presenting cells Antigen acquired immunity A carcinoma antigen

Notes de l'éditeur

  1. アロエべラと酵素の単独及び併用 活性水素水における免疫効果 と抗腫瘍効果などのメカニズムに関する研究について 具研究室 永井、花井が報告致します。
  2. はじめに研究背景です。近年、癌、心疾患、脳血管疾患などによる死亡が上位を占めるようになりました。このうち、悪性新生物による死亡数は年々増加傾向にあり、死因の 1 位を占めています。 そのため、難治性癌を克服するためにいろいろな対策が講じられています。末期医療や緩和医療によって癌で苦しまないようにする対策も充実してきました。 (☆) 癌そのものにならない予防法を推進することこそ癌克服の根本的な解決策であると考えられます。 (☆) そこで注目されるのが天然物を用いた代替医療です。代替医療は、放射線治療などによる副作用などが少なく、天然物質を組み合わせることで免疫を高め、癌の成長など遅らせることができるのではないかと考えられています。