SlideShare a Scribd company logo
1 of 127
CHRONIC OBSTRUCTIVE PULMONARY DISEASE Dr.Sarma RVSN,  M.D., M.Sc (Canada) Consultant in Medicine and Chest, President IMA – Tiruvallur Branch JN Road, Jayanagar, Tiruvallur, TN +91 98940 60593, (4116) 260593
G LOBAL INITIATIVE    FOR CHRONIC O BSTRUCTIVE L UNG D ISEASE GOLD NHLBI AND WHO COLLABORATIVE INITIATIVE
WORLD COPD DAY November 19, EVERY YEAR Raising COPD Awareness Worldwide
PURPOSE OF THIS TALK RELEVANCE Present the  Global strategy for the  Diagnosis, Management  and Prevention  of COPD (updated Nov 2004) BASED ON THE GOLD, NICE NAEPP, CDC, BTS, GUIDELINES ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
DEFINITIONS
DEFINITION OF COPD CONTENTS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
1. CHRONIC BRONCHITIS 2. EMPHYSEMA ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
DEFINITION OF COPD CONTENTS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
OBSTRUCTIVE LUNG DISEASES ASTHMA COPD REVERSIBILITY OF AIR WAY OBSTRUTION FULL NONE ASTHMA EMPHYSEMA CHRONIC BRONCHITIS
EPIDEMIOLGY  OF COPD
KEY POINTS CONTENTS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
BURDEN OF ILLNESS ,[object Object],[object Object],[object Object],[object Object],[object Object],MORTALITY Deaths Cause 64,574 Diabetes 94,828 Accidents 114,318 COPD 158,060 CVA 534,947 Cancer 724,269 CHD
COPD PREVALENCE 2000 MORTALITY TRENDS 1965 - 2000 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],% Change Cause - 7% All other + 32% Accident + 163% COPD - 39% CVA - 64% Cancer - 59% CHD
WHAT IS WRONG ? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],MORBIDITY Consultations Year ↑↑↑↑ 2010 13.9 million 2000 11.8 million 1995 10.1 million 1990 7.4 million 1985 6.1 million 1980
SMOKING - THE CULPRIT
RISK FACTORS FOR COPD  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],MOST IMP RISK
WOMEN SMOKERS PASSIVE SMOKERS
TENDER AGE GROUPS COLLEGE STUDENTS INTENSE CAUSE FOR CONCERN ?
COPD NH – EFFECT OF SMOKING  Mortality among women smokers is on the rise globally
PATHOGENESIS  AND PATOLOGY
PATHOGENESIS  NOXIOUS AGENT (tobacco smoke, pollutants, occupational exposures COPD CONTENTS Genetic factors Respiratory infection Others ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
PATHOGENESIS  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
PATHOGENESIS  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],ATOPY
SHIFT IN THE DELICATE BALANCE  PROTEASES ANTI PROTEASES Nutrophil elastase Cathepsisns MMP-1, MMP- 9, MMP – 12 Granzymes Perforins Alpha  1  Anti-trypsin SLP  1 , Elastin, TIMPs COPD
PATHOLOGY  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],CONTENTS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
PATHOLOGY  in COPD Normal bronchial architecture ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],COPD
DISSECTING MICROSCOPIC APPEARENCE Normal parenchymal  architecture Emphysematous  Lung architecture
PATHOLOGY – COPD  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],ASTHMA ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
PULMONARY HYPERTENSION IN COPD Normal Pulmonary Artery ,[object Object],[object Object]
CLINICAL FEATURES
CHRONIC BRONCHITIS  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],EMPHYSEMA ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
CHRONIC BRONCHITIS  EMPHYSEMA BLUE BLOTTER  PINK PUFFER
ALPHA 1  ANTITRYPSIN  ↓   ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],EMPHYSEMA
ALPHA1 ANTITRYPSIN ↓  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],A 1 AT LEVELS
CLINICAL SIGNS  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],SPIROMETRY
MRC DYSPNOEA SCALE  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],ABOUT SMOKING Too breathless to leave house or breathless while dressing 4 Stops for breath on walking 100 m or  after 2 or 3 minutes continuously 3 Walks slower than contemporaries or  has to stop for breath while walking alone 2 Short of breath when walking uphill or while hurrying to catch a bus or train  1 No breathlessness except on  strenuous exercise 0 Degree of breathlessness - related activity Grade
OXYGEN COST DIAGRAM  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],OCCUPATIONAL Slow up hill walking Medium up hill walk Brisk walking on level 0 10 Sleeping Sitting Slow walking Light shopping Heavy shopping Medium walking Self washing Bed making Brisk up hill walk
PROGNOSTIC FACTORS  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],‘ SUPPORT’ STUDY
DIFF. Dx. of COPD & ASTHMA  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],WHY D.D  WITH ASTHMA ? Change > 15% Change < 15% Reversibility ICS IBD (Ipa+Salm) Most IMP Rx. Normal or Obstru. Obstructive Spirometry Useful ad on Rx. Not useful Anti leukotrn. Variable, static Progressive Course Episodic Persistent Dyspnea Mucoid or none Productive Sputum Nearly all Rare Age < 35 May or may not be Nearly all Smoker ASTHMA COPD Clinical
COPD IMAGES
CHEST SKIAGRAMS  OF EMPHYSEMA
V- P MISMATCH  NUCLEOTIDE IMAGING
CHEST SKIAGRAM OF CHRONIC BRONCHITIS
CHEST LATERAL VIEW CHRONIC BRONCHITIS
HRCT – NORMAL CHEST
HRCT – EMPHYSEMA
HRCT – EMPHYSEMA
ASSESSMENT  OF STABLE COPD
MANAGEMENT OF COPD  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Rx. OBJECTIVES
ASSESSMENT OF COPD  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],MANAGEMENT ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
ASSESSMENT OF COPD  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],SYMPTOMS EXPOSURE COUGH SPUTUM DYSPNEA SMOKING OCCUPATION INDOOR / OUTDOOR  Air Pollution  SPIROMETRY IS A MUST +  or  - More than  one month Age 35 +
ASSESSMENT OF COPD  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],MANAGEMENT ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
OTHER INVESTIGATIONS  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],TESTS
NORMAL AND COPD  SPIROMETRY
WITH BRONCHODILATOR  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],REVERSIBILITY PROTOCOL ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
WITH STEROIDS  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],REVERSIBILITY PROTOCOL ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
WHAT IS REVERSIBILITY ?  ,[object Object],[object Object],[object Object],[object Object],[object Object],TESTING ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
SEVERITY OF COPD  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],FACTORS
RISK REDUCTION STRATEGIES
IF ONE QUITS SMOKING  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],NO TOMORROW! * Packets per day x Years of smoking = Pack Years
[object Object],[object Object],[object Object],RISK FACTORS REDUCTION  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],5 RELAPSE TRIGGERS
NICOTINE REPLACEMENTS  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],DRUG TO QUIT ?
COPD MANAGEMENT LATEST GUIDELINES
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],GOALS OF MANAGEMENT  MANAGEMENT ,[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],OUTCOME MEASURES  HOW TO ASSESS? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],MANAGEMENT - IBD  BRONCHO-  DILATORS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],BUT UNFORTUNATELY  MANAGEMENT ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],MANAGEMENT  RULES THE RULES ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],IS IT A PARADOX ?  BRONCHO DILATORS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
BRONCHODILATION  SYNERGISM IPATROPIUM SABA and LABA
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],BRONCHODILATORS ß AGONISTS ,[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],BRONCHODILATORS ANTI ACH ,[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],CORTICOSTEROIDS ORAL STEROIDS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],BRONCHODILATORS THEOPHYLLINE ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],MANAGEMENT  INHALED Rx. ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],MANAGEMENT  NO SYSTEMIC STEROIDS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
MANGEMENT AS PER STAGING
[object Object],[object Object],[object Object],[object Object],MANAGEMENT -  STAGE 0 AT RISK  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],MANAGEMENT –  STAGE I   MILD COPD ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],MANAGEMENT –  STAGE II   MODERATE COPD ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],MANAGEMENT –  STAGE III   SEVERE COPD ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],MANAGEMENT –  STAGE IV   V. SEVERE COPD ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
DRUG DELIVERY SYSTEMS - OPTIONS
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],DRUG DELIVERY - OPTIONS  DRUG DELIVERY ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
NEBULISED THERAPY ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
EDUCATION AND REHABILITATION
REHABILITATION  For the lungs to get more air PURSED-LIP BREATHING (like breathing out slowly into a straw) INHALE EXHALE
REHABILITATION  For the lungs to get more air DIAPHRAGMATIC BREATHING Sit comfortably and  relax your shoulders  Put one hand on your abdomen. Now inhale slowly through your nose. (Push your abdomen out while you breathe in)  Then push in your abdominal muscles and breathe out using the pursed-lip technique Note:  •  Repeat the above maneuver three times and then take a little rest. • This exercise can be done many times a day.  3. Then push in your abdominal muscles and breathe out using the pursed-lip technique. (You should feel your abdomen go down)  2. Put one hand on your abdomen. Now inhale slowly through your nose. (Push your abdomen out while you breathe in)  1. Sit comfortably and relax your shoulders.
HEALTH EDUCATION – TEAM WORK
EXACERBATIONS RESP. FAILURE
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],MANAGEMENT – REFERRAL  OXIGENERATOR
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],D.D. of EXACERBATIONS WHEN SUSPECT? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],MANAGE EXACERBATIONS WHAT EXTRA ? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
LONG TERM OXYGEN THERAPY ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],INDICATIONS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
CORPULMONALE ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],FEATURES ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],RESPIRATORY FAILURE RESP. FAILURE ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],LUNG RESECTION SURGERY ,[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],WHAT ELSE WE CAN GIVE  WHAT NOT ! ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
COPD - FUTURE DEVELOPMENTS
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],FUTURE DEVELOPMENTS  NEXT DECADE ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],TAKE HOME MESSAGES
SELF SCREENING
Do you know what COPD is ?  This chronic lung disease is a major cause of illness.  Many people have it and yet don’t know it.  If you answer these questions, it will help you find out if you could have COPD.     1.  Do you  cough several times most days?     Yes ___ No  ___   2.  Do you bring up phlegm or mucus most days?    Yes ___ No  ___   3.  Do you get out of breath more easily than others your age?   Yes ___ No  ___   4.  Are you older than 40 years?    Yes ___ No  ___   5.  Are you a current smoker or an ex-smoker?       Yes ___ No  ___ If you answered yes to three or more of these questions,  ask your doctor if you might have  COPD and should have a simple breathing test.  If COPD is found early, there are steps you  can take to prevent further lung damage and make you feel better.    Take time to think about your lungs……Learn about COPD ! Could it be COPD?
ASTHMA V/s COPD Take HOME GUIDE
ASTHMA V/s COPD ETIOLOGICAL BASIS Smoking is the noxious ag. No noxious external agent Any body may be effected Innate Atopy is essential Chronic exposure -Noxious Sensitizing trigger needed COPD ASTHMA
ASTHMA V/s COPD PATHOLOGY Disease of alveloli, bronchi Small airways - bronchioles Alveolar destruc. Br fibrosis No destruction or fibrosis Primary ↑ in bronchial tone Secondary bronchospasm Destructive Inflammation Primarily Allergic Inflamm. COPD ASTHMA
ASTHMA V/s COPD PATHOGENESIS CD 8 T, MF, Neutrophils CD4 T, Mast cells, Eosino LT B4, IL 8, TNF- α LT D4, IL 4, IL 5, - Th2 ↑  Proteases,  ↓ in antiprote. ↑↑  IgE + other atopic disea. Emphysema,  Bronchial fibr. Airway remodeling occurs Progressive destr. inflamm. Recurrent allergic inflamm. COPD ASTHMA
ASTHMA V/s COPD CLINICAL FEATURES Progressive dyspn, Hr. Gr. Episodic dyspnea – moder. Perennial symptoms Seasonal symptoms Sputum purulent & copious Sputum mucoid or none Chronic, progressive, Exaca Episodic, recurrent, normal Age always > 35 yrs, smoke Young subjects, any age COPD ASTHMA
ASTHMA V/s COPD SPIROMETRY Irreversible - < 15 %  ↑ Reversible - > 15 %  ↑ Resp. failure,Corpulmonale Resp. failure rare  FEV 1  ÷ FVC < 60% FEV 1  ÷ FVC < 70% FEV 1  < 70% may be < 40% FEV 1  < 80% but > 60% Always obstructive pattern Normal or obstructive COPD ASTHMA
Treatment ASTHMA V/s COPD. - Rx. LTA have no role at all LTA are very useful Cromolyn, Ketotifen no use Mast cell stabilizers useful LTOT must in stage III and IV LTOT not needed mostly Ipatrop., Tiotrop. are first line Ipatropium add on only SR Theophylline contraindic. SR Theophylline?? some role Oral steroids in stage III & IV Oral steroids have little role SABA not much, ICS useful SABA for acute attacks LABA + Antibiotics – Ac. exa ICS are the main stay Quitting of smoking crucial Relievers and Preventers COPD ASTHMA
“ The old order changeth yielding place to new; Lest, one good custom should corrupt the world.” This is most pertinent today  to Asthma and COPD Tennyson Sir Lord, Alfred Holm and Harris & NEJM
PREVENT COPD
THE  DEADLIEST  DEVIL
SURE TO GRAVE
AND FINALLY Tell me what harm smoking  does not  cause  ??
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],PROVEN DISASTERS  TELL ME THE ORGAN SPARED ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Most of these effects have dose-response relationship.  Most of them are reversible if smoking is stopped early. Reducing the # reduces the risk – inverse response.  If we are a smoker, let us  quit  smoking – set an example. Let us motivate every month  at least one  person to quit. What right we have, to make others passive smokers? The Onus here is on us
Pledge to stop smoking
WHAT CAN WE DO ??
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],MY SINS  SINS PUNYAS IF CARE NOT  TO DO  THESE – THEN ALL
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],MY GAINS  HAVE NO MEANING & ARE MERELY FUTILE SINS PUNYAS
REMEMBER, WE ARE BLESSED  WITH THE OPPORTUNITY
Om Asatho maa sad gamaya Om Tamaso maa jyothir gamaya Om Mrityor maa amritam gamaya Om Sarveshaam swasthir bhavathu Om Sarveshaam shaantir bhavathu Om Shaantihi Shaantihi Shaantihi ||
A CD format  of today’s presentation  is ready 1. COPD, Asthma and basics of spirometry In addition it, also contains   2. ECG workshop presented earlier  3. Guidelines on Hypertension treatment This can be used in Computer & DVD player Important Announcement
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Resources for  COPD and Asthma
Dr.Sarma RVSN,  M.D., M.Sc (Canada) JN Road, Jayanagar, Tiruvallur, TN +91 98940 60593, (4116) 260593 PLEASE CONTACT US  Dr. Kumaran.M,  B.Sc., M.B.B.S., 10 North Raja St, Tiruvallur, TN +91 98941 10450, (4116) 260288 WE WILL MEET AGAIN SOON
NANRI, VANAKKAM

More Related Content

What's hot

Copd seminar
Copd seminarCopd seminar
Copd seminarhemin sab
 
Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease Ashraf ElAdawy
 
COPD - Chronic obstructive pulmonary disease - Aby
COPD - Chronic obstructive pulmonary disease - Aby COPD - Chronic obstructive pulmonary disease - Aby
COPD - Chronic obstructive pulmonary disease - Aby Aby Thankachan
 
CODP ( Chronic Obstructive Pulmonary Disease )
CODP ( Chronic Obstructive Pulmonary Disease )CODP ( Chronic Obstructive Pulmonary Disease )
CODP ( Chronic Obstructive Pulmonary Disease )Dr. Akram Yousif
 
COPD systemic effects and comorbidities
COPD systemic effects and comorbiditiesCOPD systemic effects and comorbidities
COPD systemic effects and comorbiditiesAshique Ali
 
Clinical pharmacy COPD
Clinical pharmacy COPDClinical pharmacy COPD
Clinical pharmacy COPDaldawaa
 
Chronic obstructive airway disease (coad)
Chronic obstructive airway disease (coad)Chronic obstructive airway disease (coad)
Chronic obstructive airway disease (coad)Nandinii Ramasenderan
 
Chronic obstructive pulmonary disease (copd)
Chronic obstructive pulmonary disease (copd)Chronic obstructive pulmonary disease (copd)
Chronic obstructive pulmonary disease (copd)Rahil Dalal
 
Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease Ashraf ElAdawy
 
Chronic obstructive lung disease(copd)
Chronic obstructive lung disease(copd)Chronic obstructive lung disease(copd)
Chronic obstructive lung disease(copd)CutiePie35
 
Chronic Obstructive Pulmonary Disease (COPD) by Dr Kemi Dele
Chronic Obstructive Pulmonary Disease (COPD) by Dr Kemi DeleChronic Obstructive Pulmonary Disease (COPD) by Dr Kemi Dele
Chronic Obstructive Pulmonary Disease (COPD) by Dr Kemi DeleKemi Dele-Ijagbulu
 
Chronic obstructive pulmonary disease
Chronic obstructive pulmonary diseaseChronic obstructive pulmonary disease
Chronic obstructive pulmonary diseaseimangalal
 

What's hot (20)

Copd seminar
Copd seminarCopd seminar
Copd seminar
 
Copd ppt
Copd pptCopd ppt
Copd ppt
 
COPD ppt
COPD pptCOPD ppt
COPD ppt
 
Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease
 
COPD - Chronic obstructive pulmonary disease - Aby
COPD - Chronic obstructive pulmonary disease - Aby COPD - Chronic obstructive pulmonary disease - Aby
COPD - Chronic obstructive pulmonary disease - Aby
 
CODP ( Chronic Obstructive Pulmonary Disease )
CODP ( Chronic Obstructive Pulmonary Disease )CODP ( Chronic Obstructive Pulmonary Disease )
CODP ( Chronic Obstructive Pulmonary Disease )
 
Copd
CopdCopd
Copd
 
COPD systemic effects and comorbidities
COPD systemic effects and comorbiditiesCOPD systemic effects and comorbidities
COPD systemic effects and comorbidities
 
Clinical pharmacy COPD
Clinical pharmacy COPDClinical pharmacy COPD
Clinical pharmacy COPD
 
Chronic obstructive airway disease (coad)
Chronic obstructive airway disease (coad)Chronic obstructive airway disease (coad)
Chronic obstructive airway disease (coad)
 
Chronic obstructive pulmonary disease (copd)
Chronic obstructive pulmonary disease (copd)Chronic obstructive pulmonary disease (copd)
Chronic obstructive pulmonary disease (copd)
 
COPD back to basis
COPD back to basisCOPD back to basis
COPD back to basis
 
Copd
CopdCopd
Copd
 
Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease
 
COPD
COPD COPD
COPD
 
Chronic obstructive lung disease(copd)
Chronic obstructive lung disease(copd)Chronic obstructive lung disease(copd)
Chronic obstructive lung disease(copd)
 
COPD
COPDCOPD
COPD
 
1.1.2 drugs for copd
1.1.2 drugs for copd1.1.2 drugs for copd
1.1.2 drugs for copd
 
Chronic Obstructive Pulmonary Disease (COPD) by Dr Kemi Dele
Chronic Obstructive Pulmonary Disease (COPD) by Dr Kemi DeleChronic Obstructive Pulmonary Disease (COPD) by Dr Kemi Dele
Chronic Obstructive Pulmonary Disease (COPD) by Dr Kemi Dele
 
Chronic obstructive pulmonary disease
Chronic obstructive pulmonary diseaseChronic obstructive pulmonary disease
Chronic obstructive pulmonary disease
 

Viewers also liked

What Is COPD? Summary, Exercise & Guidelines
What Is COPD? Summary, Exercise & GuidelinesWhat Is COPD? Summary, Exercise & Guidelines
What Is COPD? Summary, Exercise & GuidelinesAdam Bentley
 
State-of-the-Art Overview of COPD and its Management
State-of-the-Art Overview of COPD and its ManagementState-of-the-Art Overview of COPD and its Management
State-of-the-Art Overview of COPD and its ManagementDr.Mahmoud Abbas
 
Lecture 6 , COPD Course Pulmonary Rehabilitation
Lecture 6 , COPD Course  Pulmonary RehabilitationLecture 6 , COPD Course  Pulmonary Rehabilitation
Lecture 6 , COPD Course Pulmonary RehabilitationDr.Mahmoud Abbas
 
Pulmonary rehabilitation
Pulmonary rehabilitationPulmonary rehabilitation
Pulmonary rehabilitationkhushali52
 
Low Back Pain: Diagnosis to Treatment!
Low Back Pain: Diagnosis to Treatment!Low Back Pain: Diagnosis to Treatment!
Low Back Pain: Diagnosis to Treatment!Bernard Racey
 
Low Back Pain
Low Back PainLow Back Pain
Low Back Paindrkmliau
 
A clinic visit by debbie kennedy to patient support group 5th novemebr 2010a
A clinic visit by debbie kennedy to patient support group 5th novemebr 2010aA clinic visit by debbie kennedy to patient support group 5th novemebr 2010a
A clinic visit by debbie kennedy to patient support group 5th novemebr 2010aGraham Atherton
 

Viewers also liked (12)

ECI COPD Course Lecture 3
ECI COPD Course Lecture 3ECI COPD Course Lecture 3
ECI COPD Course Lecture 3
 
What Is COPD? Summary, Exercise & Guidelines
What Is COPD? Summary, Exercise & GuidelinesWhat Is COPD? Summary, Exercise & Guidelines
What Is COPD? Summary, Exercise & Guidelines
 
Pulmonary rehab clinic protocol
Pulmonary rehab clinic protocolPulmonary rehab clinic protocol
Pulmonary rehab clinic protocol
 
State-of-the-Art Overview of COPD and its Management
State-of-the-Art Overview of COPD and its ManagementState-of-the-Art Overview of COPD and its Management
State-of-the-Art Overview of COPD and its Management
 
Lecture 6 , COPD Course Pulmonary Rehabilitation
Lecture 6 , COPD Course  Pulmonary RehabilitationLecture 6 , COPD Course  Pulmonary Rehabilitation
Lecture 6 , COPD Course Pulmonary Rehabilitation
 
Pulmonary rehabilitation
Pulmonary rehabilitationPulmonary rehabilitation
Pulmonary rehabilitation
 
Low back pain
Low back painLow back pain
Low back pain
 
Pathology of COPD
Pathology of COPDPathology of COPD
Pathology of COPD
 
Low Back Pain
Low  Back  PainLow  Back  Pain
Low Back Pain
 
Low Back Pain: Diagnosis to Treatment!
Low Back Pain: Diagnosis to Treatment!Low Back Pain: Diagnosis to Treatment!
Low Back Pain: Diagnosis to Treatment!
 
Low Back Pain
Low Back PainLow Back Pain
Low Back Pain
 
A clinic visit by debbie kennedy to patient support group 5th novemebr 2010a
A clinic visit by debbie kennedy to patient support group 5th novemebr 2010aA clinic visit by debbie kennedy to patient support group 5th novemebr 2010a
A clinic visit by debbie kennedy to patient support group 5th novemebr 2010a
 

Similar to C O P D By Dr Sarma

Gold - global initiative against COPD
Gold - global initiative against COPDGold - global initiative against COPD
Gold - global initiative against COPDadithya2115
 
COPD - Chronic Obstructive Pulmonary Disease
COPD - Chronic Obstructive Pulmonary DiseaseCOPD - Chronic Obstructive Pulmonary Disease
COPD - Chronic Obstructive Pulmonary DiseaseShashikiran Umakanth
 
COPD(Chronic Obstructive Pulmonary Disease)Ayurveda
COPD(Chronic Obstructive Pulmonary Disease)AyurvedaCOPD(Chronic Obstructive Pulmonary Disease)Ayurveda
COPD(Chronic Obstructive Pulmonary Disease)AyurvedaRaghavendraPujari1
 
Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease  Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease YMC Medicine
 
Ckd chief (2)
Ckd chief (2)Ckd chief (2)
Ckd chief (2)Rajiv Lal
 
Copd lecture notes
Copd lecture notesCopd lecture notes
Copd lecture noteshomebwoi
 
1_COPD_Part_1_Definition,_Epidemiology_and_Pathophysiology.pdf
1_COPD_Part_1_Definition,_Epidemiology_and_Pathophysiology.pdf1_COPD_Part_1_Definition,_Epidemiology_and_Pathophysiology.pdf
1_COPD_Part_1_Definition,_Epidemiology_and_Pathophysiology.pdframbhoopal1
 
Copd overview and update 2016
Copd overview and update 2016Copd overview and update 2016
Copd overview and update 2016Ajay Kumar
 
Copd And The Gold Guidelines 02 21 2005[2]
Copd And The Gold Guidelines 02 21 2005[2]Copd And The Gold Guidelines 02 21 2005[2]
Copd And The Gold Guidelines 02 21 2005[2]MedicineAndDermatology
 
Pnumonia21.03.2023.pptx
Pnumonia21.03.2023.pptxPnumonia21.03.2023.pptx
Pnumonia21.03.2023.pptxTanvirIslam94
 
COPD:CLINICAL REVIEW AND ANESTHESIA CONSIDERATION
COPD:CLINICAL REVIEW AND ANESTHESIA CONSIDERATIONCOPD:CLINICAL REVIEW AND ANESTHESIA CONSIDERATION
COPD:CLINICAL REVIEW AND ANESTHESIA CONSIDERATIONDr.RMLIMS lucknow
 
Non Communicable Diseases: COPD
Non Communicable Diseases: COPDNon Communicable Diseases: COPD
Non Communicable Diseases: COPDRalph Bawalan
 

Similar to C O P D By Dr Sarma (20)

Gold - global initiative against COPD
Gold - global initiative against COPDGold - global initiative against COPD
Gold - global initiative against COPD
 
Copd and anaesthesia
Copd and anaesthesiaCopd and anaesthesia
Copd and anaesthesia
 
COPD.pptx
COPD.pptxCOPD.pptx
COPD.pptx
 
COPD - Chronic Obstructive Pulmonary Disease
COPD - Chronic Obstructive Pulmonary DiseaseCOPD - Chronic Obstructive Pulmonary Disease
COPD - Chronic Obstructive Pulmonary Disease
 
COPD(Chronic Obstructive Pulmonary Disease)Ayurveda
COPD(Chronic Obstructive Pulmonary Disease)AyurvedaCOPD(Chronic Obstructive Pulmonary Disease)Ayurveda
COPD(Chronic Obstructive Pulmonary Disease)Ayurveda
 
Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease  Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease
 
Ckd chief (2)
Ckd chief (2)Ckd chief (2)
Ckd chief (2)
 
copd.pptx
copd.pptxcopd.pptx
copd.pptx
 
Copd lecture notes
Copd lecture notesCopd lecture notes
Copd lecture notes
 
COPD
COPDCOPD
COPD
 
1_COPD_Part_1_Definition,_Epidemiology_and_Pathophysiology.pdf
1_COPD_Part_1_Definition,_Epidemiology_and_Pathophysiology.pdf1_COPD_Part_1_Definition,_Epidemiology_and_Pathophysiology.pdf
1_COPD_Part_1_Definition,_Epidemiology_and_Pathophysiology.pdf
 
Copd overview and update 2016
Copd overview and update 2016Copd overview and update 2016
Copd overview and update 2016
 
Copd And The Gold Guidelines 02 21 2005[2]
Copd And The Gold Guidelines 02 21 2005[2]Copd And The Gold Guidelines 02 21 2005[2]
Copd And The Gold Guidelines 02 21 2005[2]
 
Pnumonia21.03.2023.pptx
Pnumonia21.03.2023.pptxPnumonia21.03.2023.pptx
Pnumonia21.03.2023.pptx
 
Copd
Copd Copd
Copd
 
COPD:CLINICAL REVIEW AND ANESTHESIA CONSIDERATION
COPD:CLINICAL REVIEW AND ANESTHESIA CONSIDERATIONCOPD:CLINICAL REVIEW AND ANESTHESIA CONSIDERATION
COPD:CLINICAL REVIEW AND ANESTHESIA CONSIDERATION
 
Pneumonia
Pneumonia Pneumonia
Pneumonia
 
COPD.pptx
COPD.pptxCOPD.pptx
COPD.pptx
 
COPD.pptx
COPD.pptxCOPD.pptx
COPD.pptx
 
Non Communicable Diseases: COPD
Non Communicable Diseases: COPDNon Communicable Diseases: COPD
Non Communicable Diseases: COPD
 

Recently uploaded

Call Girls Faridabad Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Faridabad Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Faridabad Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Faridabad Just Call 9907093804 Top Class Call Girl Service AvailableDipal Arora
 
Call Girls Bhubaneswar Just Call 9907093804 Top Class Call Girl Service Avail...
Call Girls Bhubaneswar Just Call 9907093804 Top Class Call Girl Service Avail...Call Girls Bhubaneswar Just Call 9907093804 Top Class Call Girl Service Avail...
Call Girls Bhubaneswar Just Call 9907093804 Top Class Call Girl Service Avail...Dipal Arora
 
Top Rated Bangalore Call Girls Ramamurthy Nagar ⟟ 9332606886 ⟟ Call Me For G...
Top Rated Bangalore Call Girls Ramamurthy Nagar ⟟  9332606886 ⟟ Call Me For G...Top Rated Bangalore Call Girls Ramamurthy Nagar ⟟  9332606886 ⟟ Call Me For G...
Top Rated Bangalore Call Girls Ramamurthy Nagar ⟟ 9332606886 ⟟ Call Me For G...narwatsonia7
 
Best Rate (Hyderabad) Call Girls Jahanuma ⟟ 8250192130 ⟟ High Class Call Girl...
Best Rate (Hyderabad) Call Girls Jahanuma ⟟ 8250192130 ⟟ High Class Call Girl...Best Rate (Hyderabad) Call Girls Jahanuma ⟟ 8250192130 ⟟ High Class Call Girl...
Best Rate (Hyderabad) Call Girls Jahanuma ⟟ 8250192130 ⟟ High Class Call Girl...astropune
 
Call Girls Bangalore Just Call 8250077686 Top Class Call Girl Service Available
Call Girls Bangalore Just Call 8250077686 Top Class Call Girl Service AvailableCall Girls Bangalore Just Call 8250077686 Top Class Call Girl Service Available
Call Girls Bangalore Just Call 8250077686 Top Class Call Girl Service AvailableDipal Arora
 
Top Quality Call Girl Service Kalyanpur 6378878445 Available Call Girls Any Time
Top Quality Call Girl Service Kalyanpur 6378878445 Available Call Girls Any TimeTop Quality Call Girl Service Kalyanpur 6378878445 Available Call Girls Any Time
Top Quality Call Girl Service Kalyanpur 6378878445 Available Call Girls Any TimeCall Girls Delhi
 
Call Girls Gwalior Just Call 8617370543 Top Class Call Girl Service Available
Call Girls Gwalior Just Call 8617370543 Top Class Call Girl Service AvailableCall Girls Gwalior Just Call 8617370543 Top Class Call Girl Service Available
Call Girls Gwalior Just Call 8617370543 Top Class Call Girl Service AvailableDipal Arora
 
Premium Bangalore Call Girls Jigani Dail 6378878445 Escort Service For Hot Ma...
Premium Bangalore Call Girls Jigani Dail 6378878445 Escort Service For Hot Ma...Premium Bangalore Call Girls Jigani Dail 6378878445 Escort Service For Hot Ma...
Premium Bangalore Call Girls Jigani Dail 6378878445 Escort Service For Hot Ma...tanya dube
 
Mumbai ] (Call Girls) in Mumbai 10k @ I'm VIP Independent Escorts Girls 98333...
Mumbai ] (Call Girls) in Mumbai 10k @ I'm VIP Independent Escorts Girls 98333...Mumbai ] (Call Girls) in Mumbai 10k @ I'm VIP Independent Escorts Girls 98333...
Mumbai ] (Call Girls) in Mumbai 10k @ I'm VIP Independent Escorts Girls 98333...Ishani Gupta
 
Call Girls Varanasi Just Call 8250077686 Top Class Call Girl Service Available
Call Girls Varanasi Just Call 8250077686 Top Class Call Girl Service AvailableCall Girls Varanasi Just Call 8250077686 Top Class Call Girl Service Available
Call Girls Varanasi Just Call 8250077686 Top Class Call Girl Service AvailableDipal Arora
 
Top Rated Bangalore Call Girls Richmond Circle ⟟ 9332606886 ⟟ Call Me For Ge...
Top Rated Bangalore Call Girls Richmond Circle ⟟  9332606886 ⟟ Call Me For Ge...Top Rated Bangalore Call Girls Richmond Circle ⟟  9332606886 ⟟ Call Me For Ge...
Top Rated Bangalore Call Girls Richmond Circle ⟟ 9332606886 ⟟ Call Me For Ge...narwatsonia7
 
(👑VVIP ISHAAN ) Russian Call Girls Service Navi Mumbai🖕9920874524🖕Independent...
(👑VVIP ISHAAN ) Russian Call Girls Service Navi Mumbai🖕9920874524🖕Independent...(👑VVIP ISHAAN ) Russian Call Girls Service Navi Mumbai🖕9920874524🖕Independent...
(👑VVIP ISHAAN ) Russian Call Girls Service Navi Mumbai🖕9920874524🖕Independent...Taniya Sharma
 
Best Rate (Guwahati ) Call Girls Guwahati ⟟ 8617370543 ⟟ High Class Call Girl...
Best Rate (Guwahati ) Call Girls Guwahati ⟟ 8617370543 ⟟ High Class Call Girl...Best Rate (Guwahati ) Call Girls Guwahati ⟟ 8617370543 ⟟ High Class Call Girl...
Best Rate (Guwahati ) Call Girls Guwahati ⟟ 8617370543 ⟟ High Class Call Girl...Dipal Arora
 
Top Rated Bangalore Call Girls Mg Road ⟟ 9332606886 ⟟ Call Me For Genuine S...
Top Rated Bangalore Call Girls Mg Road ⟟   9332606886 ⟟ Call Me For Genuine S...Top Rated Bangalore Call Girls Mg Road ⟟   9332606886 ⟟ Call Me For Genuine S...
Top Rated Bangalore Call Girls Mg Road ⟟ 9332606886 ⟟ Call Me For Genuine S...narwatsonia7
 
Call Girls Cuttack Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Cuttack Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Cuttack Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Cuttack Just Call 9907093804 Top Class Call Girl Service AvailableDipal Arora
 
Call Girls in Delhi Triveni Complex Escort Service(🔝))/WhatsApp 97111⇛47426
Call Girls in Delhi Triveni Complex Escort Service(🔝))/WhatsApp 97111⇛47426Call Girls in Delhi Triveni Complex Escort Service(🔝))/WhatsApp 97111⇛47426
Call Girls in Delhi Triveni Complex Escort Service(🔝))/WhatsApp 97111⇛47426jennyeacort
 
Call Girls Coimbatore Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Coimbatore Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Coimbatore Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Coimbatore Just Call 9907093804 Top Class Call Girl Service AvailableDipal Arora
 
Top Rated Hyderabad Call Girls Erragadda ⟟ 9332606886 ⟟ Call Me For Genuine ...
Top Rated  Hyderabad Call Girls Erragadda ⟟ 9332606886 ⟟ Call Me For Genuine ...Top Rated  Hyderabad Call Girls Erragadda ⟟ 9332606886 ⟟ Call Me For Genuine ...
Top Rated Hyderabad Call Girls Erragadda ⟟ 9332606886 ⟟ Call Me For Genuine ...chandars293
 
Book Paid Powai Call Girls Mumbai 𖠋 9930245274 𖠋Low Budget Full Independent H...
Book Paid Powai Call Girls Mumbai 𖠋 9930245274 𖠋Low Budget Full Independent H...Book Paid Powai Call Girls Mumbai 𖠋 9930245274 𖠋Low Budget Full Independent H...
Book Paid Powai Call Girls Mumbai 𖠋 9930245274 𖠋Low Budget Full Independent H...Call Girls in Nagpur High Profile
 

Recently uploaded (20)

Call Girls Faridabad Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Faridabad Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Faridabad Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Faridabad Just Call 9907093804 Top Class Call Girl Service Available
 
Call Girls Bhubaneswar Just Call 9907093804 Top Class Call Girl Service Avail...
Call Girls Bhubaneswar Just Call 9907093804 Top Class Call Girl Service Avail...Call Girls Bhubaneswar Just Call 9907093804 Top Class Call Girl Service Avail...
Call Girls Bhubaneswar Just Call 9907093804 Top Class Call Girl Service Avail...
 
Top Rated Bangalore Call Girls Ramamurthy Nagar ⟟ 9332606886 ⟟ Call Me For G...
Top Rated Bangalore Call Girls Ramamurthy Nagar ⟟  9332606886 ⟟ Call Me For G...Top Rated Bangalore Call Girls Ramamurthy Nagar ⟟  9332606886 ⟟ Call Me For G...
Top Rated Bangalore Call Girls Ramamurthy Nagar ⟟ 9332606886 ⟟ Call Me For G...
 
Best Rate (Hyderabad) Call Girls Jahanuma ⟟ 8250192130 ⟟ High Class Call Girl...
Best Rate (Hyderabad) Call Girls Jahanuma ⟟ 8250192130 ⟟ High Class Call Girl...Best Rate (Hyderabad) Call Girls Jahanuma ⟟ 8250192130 ⟟ High Class Call Girl...
Best Rate (Hyderabad) Call Girls Jahanuma ⟟ 8250192130 ⟟ High Class Call Girl...
 
Call Girls Bangalore Just Call 8250077686 Top Class Call Girl Service Available
Call Girls Bangalore Just Call 8250077686 Top Class Call Girl Service AvailableCall Girls Bangalore Just Call 8250077686 Top Class Call Girl Service Available
Call Girls Bangalore Just Call 8250077686 Top Class Call Girl Service Available
 
Top Quality Call Girl Service Kalyanpur 6378878445 Available Call Girls Any Time
Top Quality Call Girl Service Kalyanpur 6378878445 Available Call Girls Any TimeTop Quality Call Girl Service Kalyanpur 6378878445 Available Call Girls Any Time
Top Quality Call Girl Service Kalyanpur 6378878445 Available Call Girls Any Time
 
Call Girls Gwalior Just Call 8617370543 Top Class Call Girl Service Available
Call Girls Gwalior Just Call 8617370543 Top Class Call Girl Service AvailableCall Girls Gwalior Just Call 8617370543 Top Class Call Girl Service Available
Call Girls Gwalior Just Call 8617370543 Top Class Call Girl Service Available
 
Premium Bangalore Call Girls Jigani Dail 6378878445 Escort Service For Hot Ma...
Premium Bangalore Call Girls Jigani Dail 6378878445 Escort Service For Hot Ma...Premium Bangalore Call Girls Jigani Dail 6378878445 Escort Service For Hot Ma...
Premium Bangalore Call Girls Jigani Dail 6378878445 Escort Service For Hot Ma...
 
Mumbai ] (Call Girls) in Mumbai 10k @ I'm VIP Independent Escorts Girls 98333...
Mumbai ] (Call Girls) in Mumbai 10k @ I'm VIP Independent Escorts Girls 98333...Mumbai ] (Call Girls) in Mumbai 10k @ I'm VIP Independent Escorts Girls 98333...
Mumbai ] (Call Girls) in Mumbai 10k @ I'm VIP Independent Escorts Girls 98333...
 
Call Girls Varanasi Just Call 8250077686 Top Class Call Girl Service Available
Call Girls Varanasi Just Call 8250077686 Top Class Call Girl Service AvailableCall Girls Varanasi Just Call 8250077686 Top Class Call Girl Service Available
Call Girls Varanasi Just Call 8250077686 Top Class Call Girl Service Available
 
Top Rated Bangalore Call Girls Richmond Circle ⟟ 9332606886 ⟟ Call Me For Ge...
Top Rated Bangalore Call Girls Richmond Circle ⟟  9332606886 ⟟ Call Me For Ge...Top Rated Bangalore Call Girls Richmond Circle ⟟  9332606886 ⟟ Call Me For Ge...
Top Rated Bangalore Call Girls Richmond Circle ⟟ 9332606886 ⟟ Call Me For Ge...
 
(👑VVIP ISHAAN ) Russian Call Girls Service Navi Mumbai🖕9920874524🖕Independent...
(👑VVIP ISHAAN ) Russian Call Girls Service Navi Mumbai🖕9920874524🖕Independent...(👑VVIP ISHAAN ) Russian Call Girls Service Navi Mumbai🖕9920874524🖕Independent...
(👑VVIP ISHAAN ) Russian Call Girls Service Navi Mumbai🖕9920874524🖕Independent...
 
Best Rate (Guwahati ) Call Girls Guwahati ⟟ 8617370543 ⟟ High Class Call Girl...
Best Rate (Guwahati ) Call Girls Guwahati ⟟ 8617370543 ⟟ High Class Call Girl...Best Rate (Guwahati ) Call Girls Guwahati ⟟ 8617370543 ⟟ High Class Call Girl...
Best Rate (Guwahati ) Call Girls Guwahati ⟟ 8617370543 ⟟ High Class Call Girl...
 
Top Rated Bangalore Call Girls Mg Road ⟟ 9332606886 ⟟ Call Me For Genuine S...
Top Rated Bangalore Call Girls Mg Road ⟟   9332606886 ⟟ Call Me For Genuine S...Top Rated Bangalore Call Girls Mg Road ⟟   9332606886 ⟟ Call Me For Genuine S...
Top Rated Bangalore Call Girls Mg Road ⟟ 9332606886 ⟟ Call Me For Genuine S...
 
Call Girls in Gagan Vihar (delhi) call me [🔝 9953056974 🔝] escort service 24X7
Call Girls in Gagan Vihar (delhi) call me [🔝  9953056974 🔝] escort service 24X7Call Girls in Gagan Vihar (delhi) call me [🔝  9953056974 🔝] escort service 24X7
Call Girls in Gagan Vihar (delhi) call me [🔝 9953056974 🔝] escort service 24X7
 
Call Girls Cuttack Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Cuttack Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Cuttack Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Cuttack Just Call 9907093804 Top Class Call Girl Service Available
 
Call Girls in Delhi Triveni Complex Escort Service(🔝))/WhatsApp 97111⇛47426
Call Girls in Delhi Triveni Complex Escort Service(🔝))/WhatsApp 97111⇛47426Call Girls in Delhi Triveni Complex Escort Service(🔝))/WhatsApp 97111⇛47426
Call Girls in Delhi Triveni Complex Escort Service(🔝))/WhatsApp 97111⇛47426
 
Call Girls Coimbatore Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Coimbatore Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Coimbatore Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Coimbatore Just Call 9907093804 Top Class Call Girl Service Available
 
Top Rated Hyderabad Call Girls Erragadda ⟟ 9332606886 ⟟ Call Me For Genuine ...
Top Rated  Hyderabad Call Girls Erragadda ⟟ 9332606886 ⟟ Call Me For Genuine ...Top Rated  Hyderabad Call Girls Erragadda ⟟ 9332606886 ⟟ Call Me For Genuine ...
Top Rated Hyderabad Call Girls Erragadda ⟟ 9332606886 ⟟ Call Me For Genuine ...
 
Book Paid Powai Call Girls Mumbai 𖠋 9930245274 𖠋Low Budget Full Independent H...
Book Paid Powai Call Girls Mumbai 𖠋 9930245274 𖠋Low Budget Full Independent H...Book Paid Powai Call Girls Mumbai 𖠋 9930245274 𖠋Low Budget Full Independent H...
Book Paid Powai Call Girls Mumbai 𖠋 9930245274 𖠋Low Budget Full Independent H...
 

C O P D By Dr Sarma

  • 1. CHRONIC OBSTRUCTIVE PULMONARY DISEASE Dr.Sarma RVSN, M.D., M.Sc (Canada) Consultant in Medicine and Chest, President IMA – Tiruvallur Branch JN Road, Jayanagar, Tiruvallur, TN +91 98940 60593, (4116) 260593
  • 2. G LOBAL INITIATIVE FOR CHRONIC O BSTRUCTIVE L UNG D ISEASE GOLD NHLBI AND WHO COLLABORATIVE INITIATIVE
  • 3. WORLD COPD DAY November 19, EVERY YEAR Raising COPD Awareness Worldwide
  • 4.
  • 6.
  • 7.
  • 8.
  • 9. OBSTRUCTIVE LUNG DISEASES ASTHMA COPD REVERSIBILITY OF AIR WAY OBSTRUTION FULL NONE ASTHMA EMPHYSEMA CHRONIC BRONCHITIS
  • 11.
  • 12.
  • 13.
  • 14.
  • 15. SMOKING - THE CULPRIT
  • 16.
  • 18. TENDER AGE GROUPS COLLEGE STUDENTS INTENSE CAUSE FOR CONCERN ?
  • 19. COPD NH – EFFECT OF SMOKING Mortality among women smokers is on the rise globally
  • 20. PATHOGENESIS AND PATOLOGY
  • 21.
  • 22.
  • 23.
  • 24. SHIFT IN THE DELICATE BALANCE PROTEASES ANTI PROTEASES Nutrophil elastase Cathepsisns MMP-1, MMP- 9, MMP – 12 Granzymes Perforins Alpha 1 Anti-trypsin SLP 1 , Elastin, TIMPs COPD
  • 25.
  • 26.
  • 27. DISSECTING MICROSCOPIC APPEARENCE Normal parenchymal architecture Emphysematous Lung architecture
  • 28.
  • 29.
  • 31.
  • 32. CHRONIC BRONCHITIS EMPHYSEMA BLUE BLOTTER PINK PUFFER
  • 33.
  • 34.
  • 35.
  • 36.
  • 37.
  • 38.
  • 39.
  • 41. CHEST SKIAGRAMS OF EMPHYSEMA
  • 42. V- P MISMATCH NUCLEOTIDE IMAGING
  • 43. CHEST SKIAGRAM OF CHRONIC BRONCHITIS
  • 44. CHEST LATERAL VIEW CHRONIC BRONCHITIS
  • 48. ASSESSMENT OF STABLE COPD
  • 49.
  • 50.
  • 51.
  • 52.
  • 53.
  • 54. NORMAL AND COPD SPIROMETRY
  • 55.
  • 56.
  • 57.
  • 58.
  • 60.
  • 61.
  • 62.
  • 64.
  • 65.
  • 66.
  • 67.
  • 68.
  • 69.
  • 70. BRONCHODILATION SYNERGISM IPATROPIUM SABA and LABA
  • 71.
  • 72.
  • 73.
  • 74.
  • 75.
  • 76.
  • 77. MANGEMENT AS PER STAGING
  • 78.
  • 79.
  • 80.
  • 81.
  • 82.
  • 84.
  • 85.
  • 87. REHABILITATION For the lungs to get more air PURSED-LIP BREATHING (like breathing out slowly into a straw) INHALE EXHALE
  • 88. REHABILITATION For the lungs to get more air DIAPHRAGMATIC BREATHING Sit comfortably and relax your shoulders Put one hand on your abdomen. Now inhale slowly through your nose. (Push your abdomen out while you breathe in) Then push in your abdominal muscles and breathe out using the pursed-lip technique Note: • Repeat the above maneuver three times and then take a little rest. • This exercise can be done many times a day. 3. Then push in your abdominal muscles and breathe out using the pursed-lip technique. (You should feel your abdomen go down) 2. Put one hand on your abdomen. Now inhale slowly through your nose. (Push your abdomen out while you breathe in) 1. Sit comfortably and relax your shoulders.
  • 89. HEALTH EDUCATION – TEAM WORK
  • 91.
  • 92.
  • 93.
  • 94.
  • 95.
  • 96.
  • 97.
  • 98.
  • 99. COPD - FUTURE DEVELOPMENTS
  • 100.
  • 101.
  • 103. Do you know what COPD is ? This chronic lung disease is a major cause of illness. Many people have it and yet don’t know it. If you answer these questions, it will help you find out if you could have COPD.   1. Do you cough several times most days? Yes ___ No ___   2. Do you bring up phlegm or mucus most days? Yes ___ No ___   3. Do you get out of breath more easily than others your age? Yes ___ No ___   4. Are you older than 40 years? Yes ___ No ___   5. Are you a current smoker or an ex-smoker? Yes ___ No ___ If you answered yes to three or more of these questions, ask your doctor if you might have COPD and should have a simple breathing test. If COPD is found early, there are steps you can take to prevent further lung damage and make you feel better.   Take time to think about your lungs……Learn about COPD ! Could it be COPD?
  • 104. ASTHMA V/s COPD Take HOME GUIDE
  • 105. ASTHMA V/s COPD ETIOLOGICAL BASIS Smoking is the noxious ag. No noxious external agent Any body may be effected Innate Atopy is essential Chronic exposure -Noxious Sensitizing trigger needed COPD ASTHMA
  • 106. ASTHMA V/s COPD PATHOLOGY Disease of alveloli, bronchi Small airways - bronchioles Alveolar destruc. Br fibrosis No destruction or fibrosis Primary ↑ in bronchial tone Secondary bronchospasm Destructive Inflammation Primarily Allergic Inflamm. COPD ASTHMA
  • 107. ASTHMA V/s COPD PATHOGENESIS CD 8 T, MF, Neutrophils CD4 T, Mast cells, Eosino LT B4, IL 8, TNF- α LT D4, IL 4, IL 5, - Th2 ↑ Proteases, ↓ in antiprote. ↑↑ IgE + other atopic disea. Emphysema, Bronchial fibr. Airway remodeling occurs Progressive destr. inflamm. Recurrent allergic inflamm. COPD ASTHMA
  • 108. ASTHMA V/s COPD CLINICAL FEATURES Progressive dyspn, Hr. Gr. Episodic dyspnea – moder. Perennial symptoms Seasonal symptoms Sputum purulent & copious Sputum mucoid or none Chronic, progressive, Exaca Episodic, recurrent, normal Age always > 35 yrs, smoke Young subjects, any age COPD ASTHMA
  • 109. ASTHMA V/s COPD SPIROMETRY Irreversible - < 15 % ↑ Reversible - > 15 % ↑ Resp. failure,Corpulmonale Resp. failure rare FEV 1 ÷ FVC < 60% FEV 1 ÷ FVC < 70% FEV 1 < 70% may be < 40% FEV 1 < 80% but > 60% Always obstructive pattern Normal or obstructive COPD ASTHMA
  • 110. Treatment ASTHMA V/s COPD. - Rx. LTA have no role at all LTA are very useful Cromolyn, Ketotifen no use Mast cell stabilizers useful LTOT must in stage III and IV LTOT not needed mostly Ipatrop., Tiotrop. are first line Ipatropium add on only SR Theophylline contraindic. SR Theophylline?? some role Oral steroids in stage III & IV Oral steroids have little role SABA not much, ICS useful SABA for acute attacks LABA + Antibiotics – Ac. exa ICS are the main stay Quitting of smoking crucial Relievers and Preventers COPD ASTHMA
  • 111. “ The old order changeth yielding place to new; Lest, one good custom should corrupt the world.” This is most pertinent today to Asthma and COPD Tennyson Sir Lord, Alfred Holm and Harris & NEJM
  • 113. THE DEADLIEST DEVIL
  • 115. AND FINALLY Tell me what harm smoking does not cause ??
  • 116.
  • 117. Most of these effects have dose-response relationship. Most of them are reversible if smoking is stopped early. Reducing the # reduces the risk – inverse response. If we are a smoker, let us quit smoking – set an example. Let us motivate every month at least one person to quit. What right we have, to make others passive smokers? The Onus here is on us
  • 118. Pledge to stop smoking
  • 119. WHAT CAN WE DO ??
  • 120.
  • 121.
  • 122. REMEMBER, WE ARE BLESSED WITH THE OPPORTUNITY
  • 123. Om Asatho maa sad gamaya Om Tamaso maa jyothir gamaya Om Mrityor maa amritam gamaya Om Sarveshaam swasthir bhavathu Om Sarveshaam shaantir bhavathu Om Shaantihi Shaantihi Shaantihi ||
  • 124. A CD format of today’s presentation is ready 1. COPD, Asthma and basics of spirometry In addition it, also contains 2. ECG workshop presented earlier 3. Guidelines on Hypertension treatment This can be used in Computer & DVD player Important Announcement
  • 125.
  • 126. Dr.Sarma RVSN, M.D., M.Sc (Canada) JN Road, Jayanagar, Tiruvallur, TN +91 98940 60593, (4116) 260593 PLEASE CONTACT US Dr. Kumaran.M, B.Sc., M.B.B.S., 10 North Raja St, Tiruvallur, TN +91 98941 10450, (4116) 260288 WE WILL MEET AGAIN SOON