Coloides

[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],HISTORIA

DIFERENCIAS EN COMPOSICIÓN ,[object Object],[object Object],70% proteínas del LEC Determina la presión oncótica Intersticio Volumen sanguíneo Células

GENERALIDADES ,[object Object],[object Object],[object Object],[object Object]

The Journal of TRAUMA.2003,53:S82’88

Velanovich V. Crystalloids vs colloids fluid resuscitation: a meta-analysis of mortality. Surgery. 1989; 105:65 Bisonni RS. Colloids vs crystalliods in fluid resuscitation: an analisis of randomized controlled trials. J Fam Pract 1991; 32: 387-90. Schierhout G. Fluid resuscitation with colloid or crystalloid solutions in crytically ill patients: a systematic review of randomised trials. BMJ. 1998; 316: 961-964. Alderson P. Colloids vs Crystalloids for fluid resuscitation in critacally ill patients. Cochrane Database Sysr Rev. 2000 Choi, P. Crystalloids vs colloids fluid resuscitation: a systematic review. Crit Care Medicine 1999; 27: 200-10

Schierhout G. BMJ 1998, 316; 961-64

[object Object],[object Object],[object Object],[object Object],[object Object],Boldt J, Lang K. Anesth Analg 2001; 93, 405-9 Anesthesiology 1995, 82; 975-82 L. A. McIntyre. Can J Anesth, October 1, 2007; 54(10): 790 - 798.

[object Object],[object Object]

The Journal of TRAUMA.2003,53:S82’88 EFECTO DE LAS DIFERENTES SOLUCIONES EN LA EXPANSIÓN DE VOLUMEN

[object Object],[object Object],[object Object],[object Object]

OTROS EFECTOS DE LOS COLOIDES ,[object Object],[object Object],[object Object],Funk, W. Anesthesiology 1995; 82: 975-82 Salmon JB. Blood Review 1993; 7: 114-20 Lang K, Boldt J, Suttner S. Anesth Analg 2001; 93: 405-9

UNIONES CELULARES ENDOTELIALES

Inflammatory mediator release Albumin 18 x H2O NaCl

EFECTOS SECUNDARIOS EN GENERAL

CARACTERÍSTICAS DE UN COLOIDE IDEAL Boldt. J, Suttner S. Minerva Anestesiol 2005; 71: 741-58 GENERALES PROPIEDADES FARMACOCINÉTICAS Distribución solo intravascular T1/2 de 6-12 horas Disponible rápidamente No sea almacenado Barato NO TÓXICO-NO EFECTOS ADVERSOS No requerimientos especiales de almacenamiento o infusión No antigénico, No pirogénico PROPIEDADES FÍSICAS No alteraciones hemostasia Iso-oncótico No trastorno renal Isotónico No trastornos ácido básico Baja viscosidad No alteraciones del sistema inmune Contaminación fácil de detectar

Chamorro C. Emergencias 2004; 16: S28-S35

ALBÚMINA ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],BMJ 1998; 317: 235-240 Ann Intern Med 2001; 135: 149-164 NEJM 2004; 350: 2247-56

DEXTRANES ,[object Object],[object Object],[object Object],[object Object],Dextransucrosa leucunostoc mesenteroides

[object Object],[object Object],[object Object],[object Object],[object Object],DEXTRANES

EFECTOS SECUNDARIOS DEXTRANOS ,[object Object],[object Object],[object Object],[object Object]

GELATINAS ,[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],GELATINAS Stockwell MA. Anaesthesia 1992; 47: 7-9

EFECTOS SECUNDARIOS GELATINAS ,[object Object],[object Object],[object Object]

ALMIDONES HES ,[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],ALMIDONES HES

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],ALMIDONES HES

[object Object],[object Object],[object Object],[object Object],[object Object],ALMIDONES HES

DISPONIBILIDAD ,[object Object],[object Object],[object Object],[object Object],[object Object]

CONCLUSIONES ,[object Object],[object Object]

Coloides

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