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Cholesterol and you
AUGUST 2009                                                                                                     PUBLICATION # 55



About Cholesterol
                                                                                                        Special points of interest:
                                 In the bloodstream                   arterial walls. Eventually
                                 cholesterol is carried in            this buildup can narrow             Types of Cholesterol
                                 lipid particles called               your arteries and cause a
                                 lipoproteins. There are              blood clot to form, which           Cholesterol guidelines for chil-
                                 several versions of these            may lead to a heart attack          dren
                                 lipoproteins, but two are            or a stroke.
                                 relevant in cholesterol                                                  Cholesterol guidelines for adults.
                                                                      A person's cholesterol
                                 control:
                                                                      level is one part of the            LDL
                                 HDL—High density lipo-               equation for determining
                                 proteins, or good choles-            risk for cardiovascular             HDL
                                 terol, which attempts to             disease (CVD). Other
                                 remove fatty deposits of             risks for CVD include               Facts & Statistics
                                 plaque from your arteries.           smoking, obesity, high
                                                                      blood pressure, family
                                 LDL—Low density lipo-
                                                                      history of heart disease,
                                 proteins, or bad
                                                                      and age (older than 45 for
                                 cholesterol, which tends
                                                                      men and older than 55 for
                                 to leave fatty deposits that
                                                                      women).
                                 accumulate in your blood-
                                 stream and build up on


  Cholesterol Guidelines for Children and Adults
  Cholesterol Level Guidelines for Children*           Cholesterol Level Guidelines for Adults*
                  (mg/dL) :                                           (mg/dL) :
    Total Cholesterol                                 Total Cholesterol
                                                              <200 Desirable
            Acceptable = less than 170                        200-239 Borderline high
            Borderline = 170 to 199                           >240 High
            High = 200 or greater
                                                       LDL Cholesterol
                                                                                                           Inside this issue:
    LDL Cholesterol                                         <100 Optimal
            Acceptable = less than 110                      100-129 Near /above optimal
            Borderline = 110 to 129                         130-159 Borderline high
                                                                                                           Facts About LDL            2
                                                            160-189 High
            High = 130 or greater
                                                            >190 Very high
                                                                                                           Facts About HDL            2
                                                       HDL Cholesterol
                                                            <40 Low
                                                            >60 High
                                                                                                           Cholesterol Fact Sheet     3

 *Cholesterol guidelines are evaluated and updated by the National Cholesterol Education Program           About Our Company          4
 (NCEP) Expert Panel by the National Institutes of Health, National Heart, Lung, and Blood Institute.
 The latest version of the ATP III Classification of LDL, Total, and HDL Cholesterol (mg/dL) is the
 Third Report by the Panel. National Cholesterol Education Program’s Expert Panel on Blood
 Cholesterol in Children and Adolescents sets the acceptable level for children and adolescents.
CHOLESTEROL AND YOU                                                                  Page 2




                            Facts About LDL Cholesterol
   High cholesterol level, par-     those who are on                  In order to reduce LDL
   ticularly high LDL choles-       cholesterol lowering              cholesterol you should:
   terol, is a major risk factor    medication, should eat less       exercise regularly; eat a diet
   for coronary heart disease,      than 200 mg of cholesterol        that is low in cholesterol,
   heart attack, and stroke.        daily.                            saturated fat, and trans fat,
                                                                      maintain a healthy weight
   LDL levels in the blood are      Postmenopausal women
                                                                      and BMI (body mass index
   controlled by the liver and      who are diagnosed with
                                                                      = weight in pounds multi-
   the intestines. Liver            heart disease should treat
                                                                      plied by 703, then divide
   synthesizes LDL                  high LDL levels with drug
                                                                      the total by your height in
   cholesterol, and disposes it,    therapy together with a diet
                                                                      inches squared), and avoid
   and the intestinal track is      that is rich in fruits, vegeta-
                                                                      smoking.
   the site of lipoprotein          bles, whole grains, high
   absorption. Many drugs can       fiber foods, and low fat          Limit cholesterol intake to
   be used to block the             dairy products.                   300 mg daily.
   absorption of cholesterol
                                    Substituting soy protein for
   from the intestinal track.
                                    animal protein has been
   In order to lower your LDL       shown to lower LDL
   cholesterol levels, limit        cholesterol levels.
   foods that are high in
   saturated fats and trans fats.

   Individuals with high LDL
   blood cholesterol levels, or



Facts About HDL Cholesterol
  HDL cholesterol assists in
  the removal of cholesterol
  from the bloodstream.
  When LDL cholesterol is too
  high, cholesterol begins to be
  deposited into the walls of
  arteries. This attracts other
  material such as fat, calcium,
  cholesterol, cellular waste,
  and fibrin. Plaque begins to
                                    a risk factor for heart           avoid smoking, cut trans
  build up and overtime, ather-
                                    disease.                          fats from your diet, add
  osclerosis develops. This may
                                                                      soluble fiber such as fruits,
  eventually lead to a heart        HDL levels that are greater       oats, beans, and nuts), and
  attack or even a stroke. High     than 60 tend to have car-         increase the amount of
  HDL lowers your chance of         dio-protective effects.           monounsaturated fats.
  getting        atherosclerosis
  or heart disease, by remov-       Ways to raise your HDL            Consuming no more than 1
  ing the cholesterol and pre-      Cholesterol levels include:       or 2 servings of alcoholic
  venting the plaque buildup.       exercise regularly, maintain      beverages per day.
                                    a healthy weight and BMI,
  An HDL level less than 40 is
Page 3                                                                    PUBLICATION # 55


                                    Cholesterol Facts
   Coronary heart disease is         tends to protect    premen-
   the leading cause of death        opausal women from hav-
   in the United States.             ing high levels of LDL
                                     (bad) cholesterol or be at
   Over 43 percent of hospital       risk for cardiovascular dis-
   patients treated for              ease.
   coronary heart disease are
   under the age of 65.              Cholesterol levels tend to
                                     increase as we age.
   According to the United
   States Center for Disease         The process of developing
   Control, 106.9 million            atherosclerosis, usually
   American adults have a            begins in childhood. High
   blood cholesterol level of        fat diet in childhood can
   200 mg/dL or greater; 37.7        lead to fatty deposit in the
   of which have cholesterol         bloodstream of children           Keep your sodium intake at
   levels higher than 240 mg/        (Bogalusa Heart Study).           2300 mg or less daily (1
   dL. This places them at an                                          teaspoon). This will help
                                     High intake of Omega-3
   increased risk of having                                            with blood pressure control
                                     fatty acids, commonly
   heart disease or a stroke.                                          and the work load on the
                                     found in fish, is known to
                                     reduce the risk of heart          heart, particularly if you
   Everyone 20 and older
                                     disease.                          have high level of LDL
   should have their
                                                                       cholesterol.
   cholesterol levels checked
                                     A diet that is rich in soluble                                  High intake of
   at least once every five                                            Use margarine in place of
                                     fiber, fruits and whole                                         Omega-3 fatty
   years.                                                              butter to avoid saturated
                                     grains will lower blood                                         acids, commonly
                                     cholesterol levels.               fats. Choose margarines
   The overweight and obese                                                                          found in fish, is
                                                                       that have zero grams of
   are likely to have higher                                                                         known to reduce
                                     Ways to help keep control         trans fat.
   cholesterol level than the                                                                        the risk of heart
                                     of your cholesterol levels
   lean. However, even lean                                            It is important to follow a   disease.
                                     include: attending periodic
   individuals can have high                                           heart healthy diet from
                                     checks with your physician,
   cholesterol level due to                                            childhood which includes
                                     maintaining a healthy
   familial hypercholesterole-                                         plenty of fresh fruits and
                                     weight and BMI, participat-
   mia.                                                                vegetables, whole grains
                                     ing in moderate intensity
                                     exercise for at least 30          and lean meats, and
   The liver makes cholesterol,
                                     minutes per day, and eating       includes physical activity.
   which is used to make bile
                                     a diet that is low in             You can be a role model by
   acids. The liver also assists
                                     cholesterol, saturated fat,       being active and enjoying a
   in the removal of cholester-
                                     and trans fat.                    variety of healthful foods.
   ol from the blood.

   The intestines have the           When selecting food, keep
   ability to absorb cholesterol.    in mind that the first
   Sources of cholesterol in         ingredient on the Nutrition
   the intestinal track are food     Facts Panel is the one that
   and bile.                         is the main ingredient in the
                                     food.
   Estrogen, a female
   hormone, tends o raise            Always choose foods that
   HDL cholesterol levels.           have fats and oils listed later
   This property of estrogen         on in the list of ingredients.
Your Risk for Heart Disease
Determine your other risk                          low HDL cholesterol                                Increasing intake of soluble fiber
factors for heart disease
                                                   family history of early coronary heart             Reducing weight if you are overweight
If you have already diagnosed coronary
heart disease, atherosclerosis, or diabetes,       disease                                            - especially if you have metabolic syn-
the guidelines would place you into the                                                               drome
                                                   age (for men, age 45 or older; for wom-
high risk category, even if you have no            en, age 55 or older)                               Increasing physical activity—regular
symptoms of heart disease.                                                                            physical activity is recommended for
                                               Improve your cholesterol
In addition to high LDL, atherosclerosis                                                              everyone.
                                               numbers
or diabetes, other important risk factors      The new guidelines emphasize preventing                Controlling high blood pressure
for heart disease are:                         heart disease in the short- and long-term,
                                                                                                      Quitting smoking
    Cigarette smoking                          and recommend "therapeutic lifestyle chang-
                                               es (TLC)" to lower LDL. These involve:          Working with a dietitian or nutritionist is
    High blood pressure (140/90 mm                                                             extremely helpful.
    Hg and above or on blood pressure              Reducing saturated fat and cholesterol
    medication)                                    intake


                                                     About Pennington
    Mission:
    To promote healthier lives through research and education in
    nutrition and preventive medicine.
     The Pennington Center has several research areas, including:              Pennington Nutrition Series No 55, 2009
         Clinical Obesity Research
                                                                               Authors
         Experimental Obesity
         Functional Foods
         Health and Performance Enhancement                                    Beth Kalicki
         Nutrition and Chronic Diseases                                        Heli J. Roy, PhD, RD
         Nutrition and the Brain
         Dementia, Alzheimer’s and healthy aging
         Diet, exercise, weight loss and weight loss maintenance               Division of Education
    The research fostered in these areas can have a profound                   Pennington Biomedical Research Center
    impact on healthy living and on the prevention of common
    chronic diseases, such as heart disease, cancer, diabetes,                 8/10
    hypertension and osteoporosis.
     The Division of Education provides education and
    information to the scientific community and the public about
    research findings, training programs and research areas, and
    coordinates educational events for the public on various health
    issues.
     We invite people of all ages and backgrounds to participate in                           Pennington Biomedical
    the exciting research studies being conducted at the                                         Research Center
    Pennington Center in Baton Rouge, Louisiana. If you would                                   6400 Perkins Road
    like to take part, visit the clinical trials web page at                                  Baton Rouge, LA 70808
    www.pbrc.edu or call (225) 763-3000.                                                          (225) 763-2500
    clinical trials web page at www.pbrc.edu                                                      www.pbrc.edu
    or call (225) 763-3000.

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Cholesterol and you

  • 1. PBRC Cholesterol and you AUGUST 2009 PUBLICATION # 55 About Cholesterol Special points of interest: In the bloodstream arterial walls. Eventually cholesterol is carried in this buildup can narrow Types of Cholesterol lipid particles called your arteries and cause a lipoproteins. There are blood clot to form, which Cholesterol guidelines for chil- several versions of these may lead to a heart attack dren lipoproteins, but two are or a stroke. relevant in cholesterol Cholesterol guidelines for adults. A person's cholesterol control: level is one part of the LDL HDL—High density lipo- equation for determining proteins, or good choles- risk for cardiovascular HDL terol, which attempts to disease (CVD). Other remove fatty deposits of risks for CVD include Facts & Statistics plaque from your arteries. smoking, obesity, high blood pressure, family LDL—Low density lipo- history of heart disease, proteins, or bad and age (older than 45 for cholesterol, which tends men and older than 55 for to leave fatty deposits that women). accumulate in your blood- stream and build up on Cholesterol Guidelines for Children and Adults Cholesterol Level Guidelines for Children* Cholesterol Level Guidelines for Adults* (mg/dL) : (mg/dL) : Total Cholesterol Total Cholesterol <200 Desirable Acceptable = less than 170 200-239 Borderline high Borderline = 170 to 199 >240 High High = 200 or greater LDL Cholesterol Inside this issue: LDL Cholesterol <100 Optimal Acceptable = less than 110 100-129 Near /above optimal Borderline = 110 to 129 130-159 Borderline high Facts About LDL 2 160-189 High High = 130 or greater >190 Very high Facts About HDL 2 HDL Cholesterol <40 Low >60 High Cholesterol Fact Sheet 3 *Cholesterol guidelines are evaluated and updated by the National Cholesterol Education Program About Our Company 4 (NCEP) Expert Panel by the National Institutes of Health, National Heart, Lung, and Blood Institute. The latest version of the ATP III Classification of LDL, Total, and HDL Cholesterol (mg/dL) is the Third Report by the Panel. National Cholesterol Education Program’s Expert Panel on Blood Cholesterol in Children and Adolescents sets the acceptable level for children and adolescents.
  • 2. CHOLESTEROL AND YOU Page 2 Facts About LDL Cholesterol High cholesterol level, par- those who are on In order to reduce LDL ticularly high LDL choles- cholesterol lowering cholesterol you should: terol, is a major risk factor medication, should eat less exercise regularly; eat a diet for coronary heart disease, than 200 mg of cholesterol that is low in cholesterol, heart attack, and stroke. daily. saturated fat, and trans fat, maintain a healthy weight LDL levels in the blood are Postmenopausal women and BMI (body mass index controlled by the liver and who are diagnosed with = weight in pounds multi- the intestines. Liver heart disease should treat plied by 703, then divide synthesizes LDL high LDL levels with drug the total by your height in cholesterol, and disposes it, therapy together with a diet inches squared), and avoid and the intestinal track is that is rich in fruits, vegeta- smoking. the site of lipoprotein bles, whole grains, high absorption. Many drugs can fiber foods, and low fat Limit cholesterol intake to be used to block the dairy products. 300 mg daily. absorption of cholesterol Substituting soy protein for from the intestinal track. animal protein has been In order to lower your LDL shown to lower LDL cholesterol levels, limit cholesterol levels. foods that are high in saturated fats and trans fats. Individuals with high LDL blood cholesterol levels, or Facts About HDL Cholesterol HDL cholesterol assists in the removal of cholesterol from the bloodstream. When LDL cholesterol is too high, cholesterol begins to be deposited into the walls of arteries. This attracts other material such as fat, calcium, cholesterol, cellular waste, and fibrin. Plaque begins to a risk factor for heart avoid smoking, cut trans build up and overtime, ather- disease. fats from your diet, add osclerosis develops. This may soluble fiber such as fruits, eventually lead to a heart HDL levels that are greater oats, beans, and nuts), and attack or even a stroke. High than 60 tend to have car- increase the amount of HDL lowers your chance of dio-protective effects. monounsaturated fats. getting atherosclerosis or heart disease, by remov- Ways to raise your HDL Consuming no more than 1 ing the cholesterol and pre- Cholesterol levels include: or 2 servings of alcoholic venting the plaque buildup. exercise regularly, maintain beverages per day. a healthy weight and BMI, An HDL level less than 40 is
  • 3. Page 3 PUBLICATION # 55 Cholesterol Facts Coronary heart disease is tends to protect premen- the leading cause of death opausal women from hav- in the United States. ing high levels of LDL (bad) cholesterol or be at Over 43 percent of hospital risk for cardiovascular dis- patients treated for ease. coronary heart disease are under the age of 65. Cholesterol levels tend to increase as we age. According to the United States Center for Disease The process of developing Control, 106.9 million atherosclerosis, usually American adults have a begins in childhood. High blood cholesterol level of fat diet in childhood can 200 mg/dL or greater; 37.7 lead to fatty deposit in the of which have cholesterol bloodstream of children Keep your sodium intake at levels higher than 240 mg/ (Bogalusa Heart Study). 2300 mg or less daily (1 dL. This places them at an teaspoon). This will help High intake of Omega-3 increased risk of having with blood pressure control fatty acids, commonly heart disease or a stroke. and the work load on the found in fish, is known to reduce the risk of heart heart, particularly if you Everyone 20 and older disease. have high level of LDL should have their cholesterol. cholesterol levels checked A diet that is rich in soluble High intake of at least once every five Use margarine in place of fiber, fruits and whole Omega-3 fatty years. butter to avoid saturated grains will lower blood acids, commonly cholesterol levels. fats. Choose margarines The overweight and obese found in fish, is that have zero grams of are likely to have higher known to reduce Ways to help keep control trans fat. cholesterol level than the the risk of heart of your cholesterol levels lean. However, even lean It is important to follow a disease. include: attending periodic individuals can have high heart healthy diet from checks with your physician, cholesterol level due to childhood which includes maintaining a healthy familial hypercholesterole- plenty of fresh fruits and weight and BMI, participat- mia. vegetables, whole grains ing in moderate intensity exercise for at least 30 and lean meats, and The liver makes cholesterol, minutes per day, and eating includes physical activity. which is used to make bile a diet that is low in You can be a role model by acids. The liver also assists cholesterol, saturated fat, being active and enjoying a in the removal of cholester- and trans fat. variety of healthful foods. ol from the blood. The intestines have the When selecting food, keep ability to absorb cholesterol. in mind that the first Sources of cholesterol in ingredient on the Nutrition the intestinal track are food Facts Panel is the one that and bile. is the main ingredient in the food. Estrogen, a female hormone, tends o raise Always choose foods that HDL cholesterol levels. have fats and oils listed later This property of estrogen on in the list of ingredients.
  • 4. Your Risk for Heart Disease Determine your other risk low HDL cholesterol Increasing intake of soluble fiber factors for heart disease family history of early coronary heart Reducing weight if you are overweight If you have already diagnosed coronary heart disease, atherosclerosis, or diabetes, disease - especially if you have metabolic syn- the guidelines would place you into the drome age (for men, age 45 or older; for wom- high risk category, even if you have no en, age 55 or older) Increasing physical activity—regular symptoms of heart disease. physical activity is recommended for Improve your cholesterol In addition to high LDL, atherosclerosis everyone. numbers or diabetes, other important risk factors The new guidelines emphasize preventing Controlling high blood pressure for heart disease are: heart disease in the short- and long-term, Quitting smoking Cigarette smoking and recommend "therapeutic lifestyle chang- es (TLC)" to lower LDL. These involve: Working with a dietitian or nutritionist is High blood pressure (140/90 mm extremely helpful. Hg and above or on blood pressure Reducing saturated fat and cholesterol medication) intake About Pennington Mission: To promote healthier lives through research and education in nutrition and preventive medicine. The Pennington Center has several research areas, including: Pennington Nutrition Series No 55, 2009 Clinical Obesity Research Authors Experimental Obesity Functional Foods Health and Performance Enhancement Beth Kalicki Nutrition and Chronic Diseases Heli J. Roy, PhD, RD Nutrition and the Brain Dementia, Alzheimer’s and healthy aging Diet, exercise, weight loss and weight loss maintenance Division of Education The research fostered in these areas can have a profound Pennington Biomedical Research Center impact on healthy living and on the prevention of common chronic diseases, such as heart disease, cancer, diabetes, 8/10 hypertension and osteoporosis. The Division of Education provides education and information to the scientific community and the public about research findings, training programs and research areas, and coordinates educational events for the public on various health issues. We invite people of all ages and backgrounds to participate in Pennington Biomedical the exciting research studies being conducted at the Research Center Pennington Center in Baton Rouge, Louisiana. If you would 6400 Perkins Road like to take part, visit the clinical trials web page at Baton Rouge, LA 70808 www.pbrc.edu or call (225) 763-3000. (225) 763-2500 clinical trials web page at www.pbrc.edu www.pbrc.edu or call (225) 763-3000.