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Abstract Background: Hypertension is the most common non-communicable disease and the leading cause of cardiovascular disease in the world. Current management of hypertension stressed the importance of salt and diet modifications. Unfortunately, many hypertensive patients do not have proper knowledge of this, which results to inadequate practice. Therefore, there is need to develop strategies that will help to improve knowledge and practice of salt and diet modifications among hypertensive. Objective : To determine the effect of nursing intervention on knowledge and practice of salt and diet modifications among hypertensive patients. Materials and Methods : A quasi experimental design was conducted using purposive sampling to select the sample size of 38 participants. A researcher-developed questionnaire derived from the literature review and Hypertension Self-Care Activity Level Effects (H-SCALE) adapted from Warren-Find low and Seymour (2011) was used to measure knowledge and practice of salt and diet modification among the participants. Data gathered from participants were expressed using tables and percentages while research questions were answered with descriptive statistics of mean and standard deviation through statistical package for the social science software version 21. Results : the study revealed that higher percentage of the participants (81.6%) had poor of knowledge of salt and diet modification pre-intervention, also 92.1% of the participants reported poor practice before intervention. Intervention was given to the participants and results showed a positive change in knowledge and practice of salt and diet practice post-intervention. Conclusion : regular training should be given to hypertensive patients by nurses to improve their knowledge and practice of salt and diet modification for effective blood pressure control. Keywords : Hypertension, Knowledge, Practice, Salt and Diet modification, Nigeria Introduction The burden of hypertension and other noncommunicable diseases is rapidly increasing and this poses a serious threat to the economic development of many nations. Hypertension is a global public health challenge due to its high prevalence and the associated risk of stroke and cardiovascular diseases in adults. Globally, hypertension is implicated to be responsible for 7.1 million deaths and about 12.8% of the total annual deaths (World Health Organization (WHO), 2018). Africa, among other WHO regions was rated highest with increased prevalence of high blood pressure, estimated at 46% from age 25 years and above in which Nigeria contributes significantly to this increase (Okwuonu, Emmanuel, & Ojimadu 2014; Ekwunife, Udeogaranya, & Nwatu, 2018; WHO, 2018). This is so in spite of the availability to safe and potent drugs for hypertension and existence of clear treatment guidelines, hypertension is still grossly not controlled in a large proportion of.
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1 Epidemiology and Health Epidemiology and Health Volume: 36, Article ID: e2014009, 8 pages http://dx.doi.org/10.4178/epih/e2014009 REVIEW Open Access Dietary assessment methods in epidemiologic studies Jee-Seon Shim1, Kyungwon Oh2, Hyeon Chang Kim1,3 1Cardiovascular and Metabolic Diseases Etiology Research Center, Yonsei University College of Medicine, Seoul; 2Division of Health and Nutrition Survey, Korea Centers for Disease Control and Prevention, Osong; 3Department of Preventive Medicine, Yonsei University College of Medicine, Seoul, Korea Diet is a major lifestyle-related risk factor of various chronic diseases. Dietary intake can be assessed by sub- jective report and objective observation. Subjective assessment is possible using open-ended surveys such as dietary recalls or records, or using closed-ended surveys including food frequency questionnaires. Each meth- od has inherent strengths and limitations. Continued efforts to improve the accuracy of dietary intake assess- ment and enhance its feasibility in epidemiological studies have been made. This article reviews common di- etary assessment methods and their feasibility in epidemiological studies. KEY WORDS: Dietary assessment, Food frequency questionnaire, 24-hour dietary recall, Dietary record INTRODUCTION Diet is a major lifestyle-related risk factor of a wide range of chronic diseases. Changes in dietary habits have been found to reduce cancer incidence by one-third [1]. Dietary information has been useful in cardiovascular disease risk prediction [2] and consuming a nutrient-dense diet was associated with a low risk of all-cause mortality [3]. Contrary to other lifestyle risk factors (e.g., smoking), dietary exposures are very difficult to measure because all individuals eat foods, even if the amount and the kind of food consumed is various between subjects, and people rarely perceive what they eat and how much they do [4]. Inac- curate dietary assessment may be a serious obstacle of under- standing the impact of dietary factors on disease. Specific biochemical markers have been used as a surrogate to measure the dietary intake of selected nutrients or dietary components in epidemiological studies [5-7]. Previous studies have found these markers to be highly correlated with dietary intake levels, free of a social desirability bias, independent of memory, and not based on subjects’ ability to describe the type and quantity of food consumed [8]. Thus, these biochemical markers may provide more accurate measures than dietary in- take estimates do. However, a number of biomarkers have been known to provide integrated measures reflecting their absorp- tion and metabolism after consumption, and they are also af- fected by disease or homeostatic regulation, thus their values cannot be translated into the subject’s absolute dietary intake [9]. Moreover, the results based on biomarkers cannot provide dietary recommendations to modify a subject’s .
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Traditionally, physicians recruited clinical trial subjects, but pharmaceutical companies have become ever more involved through centralized campaigns. Physicians are vital to a trial and the pharmaceutical effort helps shift some of the recruitment demands away from the site to allow them to focus on the subjects. Thus, it is practical to understand if different recruitment methods could change or skew the study population. This study determines if differences or similarities occurred between subjects recruited by physicians and pharmaceutical companies. It discovered that some of both occurred. The pharmaceutical company efforts helped recruit potential subjects from the general population that were similar to subjects recruited by the physicians, but this particular campaign was limited by language which affected recruitment of Hispanic subjects. The social impact of this study provides insight about pharmaceutical company recruitment. Since the National Library of Medicine has indicated that clinical trials should reflect the broader diseased population, the efforts of the pharmaceutical company can help support the physicians’ efforts by recruiting from the broader population. Together, both efforts can create a global good by allowing the trial to reflect the population of post-approval use. These findings still raise a question about the proper balance between the two recruitment groups so that the intended characteristics of the diseased population are maintained. Because differences between physician and pharmaceutical recruited subjects can exist, the potential of one group to bias the trial results exist. As such, some analysis by recruitment method can help ensure that variations in the study population are minimal without skewing the data to create positive study results.
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# 5th lect clinical trial process
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1Epidemiology and HealthEpidemiology and HealthVolum.docx
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In this lecture on circulatory shock, Dr. Faiza, an Assistant Professor of Physiology, delves into the profound implications of inadequate blood flow throughout the body, leading to tissue damage. The session begins by defining circulatory shock and elucidating its physiological causes, including decreased cardiac output, diminished blood volume, decreased vascular tone, obstruction to blood flow, excess metabolic rate, and abnormal perfusion patterns. Dr. Faiza categorizes shock into various types, such as cardiogenic shock, hypovolemic shock, neurogenic shock, obstructive shock, anaphylactic shock, and septic shock, and explores the pathophysiological basis of each. Furthermore, the lecture examines the stages of shock, from the non-progressive phase where compensatory mechanisms aim for full recovery to the progressive phase where shock worsens steadily without intervention, potentially leading to irreversible damage. Dr. Faiza discusses therapeutic interventions for shock, including replacement therapy, blood and plasma transfusion, sympathomimetic drugs, and other adjunctive treatments like head-down positioning, oxygen therapy, and glucocorticoids.
Circulatory Shock, types and stages, compensatory mechanisms
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Design and synthesis of novel JNK inhibitors targeting liver pyruvate kinase for the treatment of non-alcoholic fatty liver disease and hepatocellular carcinoma.
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ANATOMY AND PHYSIOLOGY OF REPRODUCTIVE SYSTEM.pptx
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Circulatory Shock, types and stages, compensatory mechanisms
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