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What are the causes of low testosterone in men? 
Testosterone controls the development of male characteristics during puberty and is secreted by the 
testicles. Blood levels of testosterone is controlled by the pituitary gland in the brain. Low 
testosterone in men, also called hypogonadism, can be caused by several factors. 
Klinefelter Syndrome 
Men are usually born with one X and one Y chromosome. In Klinefelter syndrome, a male child may 
have more than one X chromosome. This leads to under production of testosterone and 
hypogonadism in men. 
Aging 
As men get older, the amount of testosterone produced in their body decreases. This occurs as a 
result of normal aging. 
Injury 
The testicles are located outside the body, so they may incur injury easily. When both testicles are 
injured in an accident or by a blow, hypogonadism or low testosterone may be the outcome. If, 
however, one testicle is injured, the other can take over testosterone production. 
Pituitary Gland 
The pituitary gland releases hormones that stimulate the testicles to secrete testosterone. Disorders 
of the pituitary gland, such as a pituitary tumor, may cause low testosterone secretion in the body. 
Obesity 
Obesity in men may lead to low testosterone. This is because there is enhanced conversion of 
testosterone to estrogen in the presence of obesity in both men and women. 
Cancer Treatment 
Chemotherapy and radiation therapy are used in the treatment of cancer. A man undergoing either 
of these treatments may experience low testosterone levels due to the destruction of cells that 
produce testosterone. This effect may be amazonaws.com temporary or permanent. 
Source: 
Mayo Clinic: Male hypogonadism 
MedlinePlus: Hypogonadism

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What are the causes of low testosterone in men?

  • 1. What are the causes of low testosterone in men? Testosterone controls the development of male characteristics during puberty and is secreted by the testicles. Blood levels of testosterone is controlled by the pituitary gland in the brain. Low testosterone in men, also called hypogonadism, can be caused by several factors. Klinefelter Syndrome Men are usually born with one X and one Y chromosome. In Klinefelter syndrome, a male child may have more than one X chromosome. This leads to under production of testosterone and hypogonadism in men. Aging As men get older, the amount of testosterone produced in their body decreases. This occurs as a result of normal aging. Injury The testicles are located outside the body, so they may incur injury easily. When both testicles are injured in an accident or by a blow, hypogonadism or low testosterone may be the outcome. If, however, one testicle is injured, the other can take over testosterone production. Pituitary Gland The pituitary gland releases hormones that stimulate the testicles to secrete testosterone. Disorders of the pituitary gland, such as a pituitary tumor, may cause low testosterone secretion in the body. Obesity Obesity in men may lead to low testosterone. This is because there is enhanced conversion of testosterone to estrogen in the presence of obesity in both men and women. Cancer Treatment Chemotherapy and radiation therapy are used in the treatment of cancer. A man undergoing either of these treatments may experience low testosterone levels due to the destruction of cells that produce testosterone. This effect may be amazonaws.com temporary or permanent. Source: Mayo Clinic: Male hypogonadism MedlinePlus: Hypogonadism