immune system notes guide

1. Chapter 17 The Immune System
Note-taking Guide
http://www.slideshare.net/hohlert/chapter-4517-notes
Lymphatic System
• Drain ___________________________________.
• Transport __________________________________.
• Carry out _____________________________________.
• Consistof_____________________________________ similartobloodvessels.
• Contain_________________________________________ to filterinterstitial fluid.
Lymphatic Organs and Tissues
• Thymus- two-lobedorgan,locatedmedial tothe lungsandsuperiortothe heart,
______________________________________________________________________________
• Lymphnodes- 600 beanshapednodes,
______________________________________________________________________________
______________________________________________________________________________
• Spleen- betweenstomachand
diaphragm,_______________________________________________________, macrophages
destroypathogens,storage of platelets, productionof fetal bloodcells,BandT cellscarryout
immune responses
• Lymphaticnodulesare eggshaped,tonsils

2. • 5 tonsils
• Pharyngeal,adenoid,twopalatine tonsils(obviousones) 2lingual tonsilsatthe base of the
tongue.
Barrier Defenses-Non- specificimmune response
• External barrierspreventpathogensfromenteringthe body:
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•
•
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•
•
•
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Internal Defenses
• Interferon- ________________________________________________________________
• Complementsystem-_______________________________________________________
• Natural killercells- _________________________________________________________
• Phagocytes- ______________________________________________________
• Macrophages- _______________________________________________________

3. Inflammationand FeverResponse
• Helps preventthe _____________________________________________________________
• Allowsmore ________________________________ to flow tothe injurysite.
• ___________________________________________________________________.
• Carries _________________________________________________ to the site faster
• Feveriscausedby ______________________________________.
• Elevatedbodytemperatureincreasesthe effectsof
__________________________________________, and speedsupbodilyreactionsandrepair.
Lymphocytes-specificimmune response
• ______________________________________________________.
• Containantigenreceptors.
• Cell-mediatedresponse- ________________________________________
• Antibodymediatedresponse- _____________________________________________________.
Antigensand Antibodies
• An antigencausesthe bodyto _____________________________________________________.
• Specific______________________________________ will reacttocertainproteinsandtoxins.
• ______________________________________________ (majorhistocompatibilitycomplex)-
unique proteinsthatidentifyyoutohelpT cellsrecognize foreigninvaders.

4. • Major roadblockto ______________________________________________.
• Antigensinduce plasmacellsto ___________________________________________ called
antibodies againstthem.
• The antibodyfitsagainstthe ______________________________________________ on the
surface of the microbe.
• Antibodiesbelongtoa groupof proteinscalled
______________________________________________________.
• Each has a distinctfunction andchemical structure.
T Cells
• The presence of ____________________________ informthe T cellstobeginattackbut it only
becomes________________________ once the foreignantigenbindswithit.
• _______________________________________ must ingestaforeignantigen,processitand
presentitto a T cell for recognition.
________________________________________________________________can do this.
• T cellsalsoneeda secondstimulatortopreventfalsealarms. ______________________ does
this.
• Once activated,the T cell _______________________ itself intoanarmy.
• Causesswollen_____________________.
3 Typesof T-cells
• HelperT cells __________________________________ ______________

5. • CytotoxicTcells __________________________________________ withprecision using
_____________________.
• MemoryT cells _________________________________________________.
B Cells
• Usuallystayin the __________________________.
• Secrete ______________________ once activatedbyT cellsandinterleukins.
• Can receive _____________________________ antigensbutrespondfastertoprocessedones
• Can become _______________ to respondtothe same antigeninthe future
AcquiredImmunity
• NaturallyAcquired
Active_________________________________________________________________________
______________________________________________________________________________.
• NaturallyAcquiredPassive-
______________________________________________________________________________
_________________________________________________________________________.
• ArtificiallyAcquiredActive-
______________________________________________________________________________
_________________________________________________________________________.

6. • ArtificiallyAcquiredPassive-
______________________________________________________________________________
_________________________________________________________________________.