This document discusses the neuro-motor system and causes of cerebral and lower motor neuron disorders. It describes the anatomy including upper and lower motor neurons, motor units, and control circuits. Common cerebral motor disorders like cerebral palsy can present with cognitive, language, or seizure issues and abnormal tone like spasticity, leadpipe, or hypotonia. Investigations include brain MRI. Lower motor neuron causes may be genetic like spinal muscular atrophy or acquired such as polio, Guillain-Barré syndrome, or peripheral neuropathy. Neuromuscular junction disorders and muscular diseases are also discussed. Cerebral palsy suggestions include normal brain function with isolated motor dysfunction and floppy hypotonia with areflexia.