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Inheriting Traits
• Eye color, nose
  shape and many
  other physical
  features are some
  of the traits that are
  inherited from
  parents.
• An organism is a
  collection of traits,
  all inherited from it
  parents.
Vocabulary
Heredity – passing of traits from parent to offspring

Genetics – the study of traits passed from parents to offspring

Trait – genetically determined variant of a characteristic

Trait vs. Characteristic – if a characteristic is “eye color”, blue
   eyes would be a possible trait

Alleles – different forms of a trait
• Every sex cell has
  one allele for each
  trait
• Genetics is the
  study of how traits
  are inherited
  through the
  interactions of
  alleles
Father of Genetics
• Gregor Mendel began experimenting with garden peas
  in 1856
• Carefully observed the pea plants, resulting in the first
  recorded study of how traits pass from one generation to
  the next
• Used the math of
  probability to
  explain heredity

• The first to trace
  one trait through
  several
  generations
Genetics in a Garden
• Each time Mendel studied a trait, he
  crossed two plants with different
  expressions of the trait and found that the
  new plants all looked like one of the two
  parents.
Genetics in a Garden
• He called these new plants hybrids
  because they received different genetic
  information, or different alleles, for a trait
  from each parent.
Genetics in a Garden
Purebred – an organism that always produces the
  same traits generation after generation
Ex. Tall plants that always produce seeds that produce
  tall plants are purebred for the trait of tall height
Self-pollination – when
  pollen from a plant is
  transferred to a flower on
  the same plant
Cross pollination – when
  pollen from a plant is
  transferred to a flower on
  a different plant

*In his experiments, Mendel
   used pollen from the
   flowers of purebred tall
   plants to pollinate by
   hand the flowers of
   purebred short plants
• Mendel found that tall plants
  crossed with short plants produced
  all tall plants.

• DOMINANT vs. RECESSIVE
• DOMINANT – Mendel called the tall form
  dominant because it dominated, or
  covered up, the short form

• RECESSIVE – He called the form that
  seemed to disappear the recessive factor
Probability – Make a prediction
• Mendel used probability (a branch of math
  that helps you predict the chance that
  something will happen.)
• His predictions were accurate because he
  worked with a large number of plants
  (almost 30,000 pea plants in 8 years),
  thereby increasing his chances of seeing a
  repeatable pattern.
Punnett Squares
• A tool used to predict
  results in genetics is
  the Punnett square.
  It helps you predict
  what offspring would
  look like.

• In a Punnett square,
  letters represent
  dominant and
  recessive alleles.
An uppercase letter stands for a dominant
                  allele




An lowercase letter stands for a recessive
                  allele
• Punnett squares show the genotype or
  the genetic makeup of an organism
  inherited from its parents
• It also shows the phenotype, which is the
  appearance of an organism (ex. Tall or
  short)
• Most cells in your
  body have two alleles
  for every trait. The
  alleles are located on
  chromosomes within
  the nucleus.

Ex. Trait - Height
T allele would be for Tall
t allele would be for
   short
• An organism with
  two alleles that are
  the same is called
  homozygous. Ex.
  TT

• An organism that
  has two different
  alleles for a trait is
  called
  heterozygous.
  Example Tt
Making a Punnett Square
     B         B

b    Bb       Bb


b    Bb        Bb
Dominance
• An allele’s effect is Dominant or recessive.
• More common traits tend to be dominant and
  less common are recessive.
                 Ex. T – Tall, t – short
                   TT would be Tall
  Tt would still be Tall (because big T is dominant
                   tt would be short
Activity

     A = normal
     pigmentation

     a = albinism




1.    What fraction of this couple’s children would you expect to be AA?
2.    What fraction of this couple’s children would you expect to be Aa?
3.    What fraction of this couple’s children would you expect to be aa?
4.    What fraction of this couple’s children would you expect to have normal
      pigmentation?
5.    What fraction of this couple’s children would you expect to have albinism?
Mendel’s Laws of Genetics
1. Law of Segregation
2. Law of Independent Assortment
1. Law of Segregation
• For any particular trait, the pair of alleles of
  each parent separate and only one allele
  passes from each parent on to an
  offspring.
• Which allele in a parent’s pair is inherited
  is a matter of chance.
Ex. Each parent gives only one allele to an
 egg or sperm. When fertilization
 occurs, the offspring’s gene pair is
 determined by which allele each sex cell
 carried.
2. Law of Independent Assortment
• Different pairs of alleles are passed to
  offspring independently of each other.
• This means that the offspring can have
  combinations of genes that neither parent
  has. So, the offspring can look differently
  than both parents.

Ex. Explains why the human inheritance of a
 particular eye color does not increase or
 decrease the likelihood of having 6 fingers on
 each hand.
Types of Genetic Crosses
• Monohybrid cross – cross involving
  single trait
Ex. Flower color
• Dihybrid cross – cross involving two traits
Ex. Flower color and plant height
More Words
• P Generation – parent generation in a
  genetic cross
• F1 generation – first generation offspring
  resulting from a cross between parents
• F2 generation – second generation
  offspring resulting from a cross between
  the F1 offspring
Sex Determination
XX – girls
XY – boys

Females produce eggs
 with X chromosomes
 only.
Males produce sperm with
 X and Y chromosomes
Sex-Linked Disorders
• An allele inherited on a sex
  chromosome is called a
  sex-linked gene.
Ex. Color blindness is a sex-
  linked disorder in which
  people cannot distinguish
  between certain
  colors, particularly red and
  green
• This trait is a recessive allele on the X
    chromosome.
  • Because males have only one X
    chromosome, a male with this allele on his
    X chromosome is color blind.
  • A color blind female occurs only when both
    of her X chromosomes have the allele for
    this trait.

So, are you color blind or
not?
Pedigree
• A visual tool for
  following a trait through
  generations of a family.
• Males – squares,
  Females – circles
• Completely filled circle
  or square – trait is seen
  in that person
• Half colored – indicate
  carriers
• Empty – do not have
  the trait and are not
  carriers
Homework
1. You are newly married and want to find
   out the probability of you having kids with
   blue eyes. You have brown eyes, while
   your spouse has blue eyes. Will you
   have kids with blue eyes? And if so, how
   many?
2. What other sex-linked genetic disorders
   are there? Give examples and a brief
   description.

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Genetics and Heredity

  • 1.
  • 2. Inheriting Traits • Eye color, nose shape and many other physical features are some of the traits that are inherited from parents. • An organism is a collection of traits, all inherited from it parents.
  • 3. Vocabulary Heredity – passing of traits from parent to offspring Genetics – the study of traits passed from parents to offspring Trait – genetically determined variant of a characteristic Trait vs. Characteristic – if a characteristic is “eye color”, blue eyes would be a possible trait Alleles – different forms of a trait
  • 4. • Every sex cell has one allele for each trait • Genetics is the study of how traits are inherited through the interactions of alleles
  • 5. Father of Genetics • Gregor Mendel began experimenting with garden peas in 1856 • Carefully observed the pea plants, resulting in the first recorded study of how traits pass from one generation to the next
  • 6. • Used the math of probability to explain heredity • The first to trace one trait through several generations
  • 7. Genetics in a Garden • Each time Mendel studied a trait, he crossed two plants with different expressions of the trait and found that the new plants all looked like one of the two parents.
  • 8. Genetics in a Garden • He called these new plants hybrids because they received different genetic information, or different alleles, for a trait from each parent.
  • 9. Genetics in a Garden Purebred – an organism that always produces the same traits generation after generation Ex. Tall plants that always produce seeds that produce tall plants are purebred for the trait of tall height
  • 10. Self-pollination – when pollen from a plant is transferred to a flower on the same plant Cross pollination – when pollen from a plant is transferred to a flower on a different plant *In his experiments, Mendel used pollen from the flowers of purebred tall plants to pollinate by hand the flowers of purebred short plants
  • 11. • Mendel found that tall plants crossed with short plants produced all tall plants. • DOMINANT vs. RECESSIVE
  • 12. • DOMINANT – Mendel called the tall form dominant because it dominated, or covered up, the short form • RECESSIVE – He called the form that seemed to disappear the recessive factor
  • 13. Probability – Make a prediction • Mendel used probability (a branch of math that helps you predict the chance that something will happen.) • His predictions were accurate because he worked with a large number of plants (almost 30,000 pea plants in 8 years), thereby increasing his chances of seeing a repeatable pattern.
  • 14. Punnett Squares • A tool used to predict results in genetics is the Punnett square. It helps you predict what offspring would look like. • In a Punnett square, letters represent dominant and recessive alleles.
  • 15. An uppercase letter stands for a dominant allele An lowercase letter stands for a recessive allele
  • 16. • Punnett squares show the genotype or the genetic makeup of an organism inherited from its parents • It also shows the phenotype, which is the appearance of an organism (ex. Tall or short)
  • 17. • Most cells in your body have two alleles for every trait. The alleles are located on chromosomes within the nucleus. Ex. Trait - Height T allele would be for Tall t allele would be for short
  • 18. • An organism with two alleles that are the same is called homozygous. Ex. TT • An organism that has two different alleles for a trait is called heterozygous. Example Tt
  • 19. Making a Punnett Square B B b Bb Bb b Bb Bb
  • 20. Dominance • An allele’s effect is Dominant or recessive. • More common traits tend to be dominant and less common are recessive. Ex. T – Tall, t – short TT would be Tall Tt would still be Tall (because big T is dominant tt would be short
  • 21.
  • 22. Activity A = normal pigmentation a = albinism 1. What fraction of this couple’s children would you expect to be AA? 2. What fraction of this couple’s children would you expect to be Aa? 3. What fraction of this couple’s children would you expect to be aa? 4. What fraction of this couple’s children would you expect to have normal pigmentation? 5. What fraction of this couple’s children would you expect to have albinism?
  • 23. Mendel’s Laws of Genetics 1. Law of Segregation 2. Law of Independent Assortment
  • 24. 1. Law of Segregation • For any particular trait, the pair of alleles of each parent separate and only one allele passes from each parent on to an offspring. • Which allele in a parent’s pair is inherited is a matter of chance.
  • 25. Ex. Each parent gives only one allele to an egg or sperm. When fertilization occurs, the offspring’s gene pair is determined by which allele each sex cell carried.
  • 26. 2. Law of Independent Assortment • Different pairs of alleles are passed to offspring independently of each other. • This means that the offspring can have combinations of genes that neither parent has. So, the offspring can look differently than both parents. Ex. Explains why the human inheritance of a particular eye color does not increase or decrease the likelihood of having 6 fingers on each hand.
  • 27.
  • 28. Types of Genetic Crosses • Monohybrid cross – cross involving single trait Ex. Flower color • Dihybrid cross – cross involving two traits Ex. Flower color and plant height
  • 29. More Words • P Generation – parent generation in a genetic cross • F1 generation – first generation offspring resulting from a cross between parents • F2 generation – second generation offspring resulting from a cross between the F1 offspring
  • 30.
  • 31. Sex Determination XX – girls XY – boys Females produce eggs with X chromosomes only. Males produce sperm with X and Y chromosomes
  • 32. Sex-Linked Disorders • An allele inherited on a sex chromosome is called a sex-linked gene. Ex. Color blindness is a sex- linked disorder in which people cannot distinguish between certain colors, particularly red and green
  • 33. • This trait is a recessive allele on the X chromosome. • Because males have only one X chromosome, a male with this allele on his X chromosome is color blind. • A color blind female occurs only when both of her X chromosomes have the allele for this trait. So, are you color blind or not?
  • 34. Pedigree • A visual tool for following a trait through generations of a family. • Males – squares, Females – circles • Completely filled circle or square – trait is seen in that person • Half colored – indicate carriers • Empty – do not have the trait and are not carriers
  • 35.
  • 36.
  • 37.
  • 38. Homework 1. You are newly married and want to find out the probability of you having kids with blue eyes. You have brown eyes, while your spouse has blue eyes. Will you have kids with blue eyes? And if so, how many? 2. What other sex-linked genetic disorders are there? Give examples and a brief description.