1. Drugs in viva
Kripali rai
080201336

2. Catogaries:
• Emergency drugs
• Antibiotics
• Drugs in asthama
• Steroids
• Anticonvulsants
• Cardiac drugs

3. antibiotics
• Ceftazidime, cefotaxime.
• Procaine penicillin, benzyl penicillin,
benzathin penicillin, ampicillin.
• Gentamycin, amikacin, streptomycin.

4. Cephalosporins:
• Ceftazidime :
3rdgeneration(pseudomonas).
route: parentral.
side effects: neutropenia,
thrombocytopenia, ↑ serum
transaminase and blood urea.
use: febrile neutropenia.

5. Cephalosporins:
• Cefotaxime: not active against
anaerobes
route: parentral
indications: meningitis, life
threatening resistant/ hospital
acquired infection,septicemia &
infections in immunocompromised.

6. Cephalosporins:
Adverse effects:
• Pain (thrombophlebitis)
• Diarrhoea
• Hypersenstivity
• Nephrotoxicity
• Bleeding
• Neutropenia, thrombocytopenia

7. Cephalosporins:
Uses:
• Alternative to PnG
• Respiratory, soft tissue & urinary
infections,Septicemia.
• Surgical prophylaxis
• Gonorrhoea,thyphoid
• Hospital acquired infections &
infections in neutropenic patients.

8. ß-lactam antibiotics:
Penicillin-g(benzyl penicillin):
• Narrow spectrum gram +ve.
• Route: intravenous.
• Short acting.
• Dose: mild infections :50,000U–
100,000U/kg/day in divided doses
every 4-6 hrsX7 days.
Severe infections :200,000U–
600,000U/kg/day in divided doses
every 2-6 hrsX14 days.

9. ß-lactam antibiotics:
Procaine penicillin :
• Route: intramuscular.
• Long acting.
• Dose: 150,000 – 300,000U IM OD or
BID X7 days.

10. ß-lactam antibiotics:
Benzathene penicillin:
• Route: intramuscular.
• Long acting.
• Dose: 0.6 – 1.2million U IM monthly.

11. ß-lactam antibiotics:
Adverse effects:
• Local irritancy & direct toxicity.
• Hypersensitivity.
• Jarisch-herxheimer reaction.

12. ß-lactam antibiotics:
Uses:
• Streptococcal, pneumococcal,
meningococcal infections.
• Syphillis, diphtheria, tetanus and gas
gangrene.
• Rare infections.
• Prophylactic uses: RF, bacterial
endocarditis, agranulocytosis.

13. ß-lactam antibiotics:
Ampicillin: oral/IV/IM
• Uses: UTI.
respiratory infections.
meningitis.
gonorrhoea.
typhoid, cholecystitis.
bacillary desentry.
SABE.
septicaemias.

14. Aminoglycosides:
Streptomycin: gram –ve
• Route: intramuscular.
• Uses: tuberculosis(15mg/kg).
SABE.
Tuberculocidal
Acts on extracellular bacilli
plague.
Category ІІ in initial phase (3Xper
tularemia.
week)

15. Aminoglycosides:
Gentamycin: more potent broader
spectrum.
• Route: parentral/eye drops/skin
creams.
• Uses: respiratory infections.
pseudomonas,klebsiella/proteus
meningitis.

16. Aminoglycosides:
• Amikacin: widest spectrum

17. Aminoglycosides:
Adverse effects:
• Ototoxicity.
• Nephrotoxicity.
• Neuromuscular blockage.
• Foetal ototoxicity during pregnancy.
• Avoid: amphotericin B, vancomycin,
cyclosporin, cysplatin.

18. Asthalin respules:
• Inhalation through mouth via a
suitable nebulizer.
• beta 2 -agonist providing short-acting
(4-6 hours) bronchodilatation with a
fast onset (within 5 minutes) in
reversible airways obstruction.
• 10%-20% of the dose reaches the
lower airways.

19. Asthalin respules:
• Measured amount of drug + NS 2.5-
3ml.
• Minimum starting dose: 0.5 ml (2.5
mg of salbutamol), diluted to 2-2.5 ml
with sterile NS (<12 yrs).

20. Rotahaler:

21. Rotahaler:

22. Dextrose:
• Hypoglycemia.
• 0.5 g/kg (2 mL/kg of 25% dextrose)
IV infusion over 2-3mins.
• 1 mg glucagon SC/IM.