1. Paediatrics seminar

2. COMPOSITION OF BODY FLUIDS
&
FLUID LOSS

3. Total Body Water
TOTAL BODY FLUID IS DIVIDED INTO 2
COMPARTEMENTS:-
1.Intracellular(ICF)
2.Extracellular(ECF)

4. INTRACELLULAR COMPARTMENT
 Consists of 40% of body weight

5. EXTRACELLULAR COMPARTMENT
Consists of 20% of body water
 Interstitial fluid- 80% of ECF
 Plasma- 20% of ECF
 Transcellular fluid
 Gastrointestinal
 CSF
 Peritonial & ocular

6. ICF & ECF
ICF (30-40%)
Interstitiial
(15%) Plasma(5%)

8. An equilibrium is always
maintained between
&
ICF ECF

9. Sodium ion
Pottasium ion

10. Intracellular Anions
Plasma anions
Chloride ion
Cl-
HCO3- 3 10 Cl-
14 6 2 40 HCO3-
24 Proteins 107
104 Proteins
Phophates
Others
Phosphate
s

11. FLUID LOSS
Plasma water loss
dehydration,anaemia
polycythemia,heart failure
hypoalbuminemia,
abnormal plasma osmolality

12. Fluid loss in neonates
Insensible water loss ----15 –30ml/kg
Renal water loss -----------60—90ml/kg
Stool water loss-------------10 ml/kg
Growth --------------10—15 ml/kg
Water of oxidation-----------15---18ml/kg

13. Insensible fluid loss in neonates
causes -----
Increase in surface area per unit body mass
Decrease in subcutaneous fat tissue
Thin epidermis
Increased permeability of epidermis