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The Reference in Single Source CT
SOMATOM Definition Edge




                                          Answers for life.
SOMATOM Definition Edge
Siemens CT Vision




    Today’s reality                                 Our approach                                    • to maximize workflow efficiency
    Better healthcare for all patients is a key     In order to meet our share of responsibility    • to make state-of-the-art CT affordable
    priority for the entire medical industry.       in addressing these challenges, Siemens,        • to set the standard in customer care
    But the realities of clinical practice often    from the earliest stages of research, product
    make this simple-to-understand goal quite       development, and design, relies upon the        Our vision
    difficult to realize: staying within budgets,   advice and recommendations of external          As a partner to our customers, we create
    reducing hospital stays, speeding up time to    medical experts to determine our focus –        CT innovations that lift clinical practice to
    diagnosis, and dealing with personnel issues,   and this focus has been on the needs and        the next level of excellence and enable wide
    while maintaining high clinical standards       demands of our end users. Over the years,       access to better patient care. We believe
    and throughput. At the same time, patients      this focus has been fine-tuned in four          that even the farthest technical horizons
    demand better and faster results.               key areas:                                      are temporary and can be surpassed
                                                    • 	to lead technological and medical            with consistent dedication to improved
                                                       advancement                                  healthcare. This visionary approach, backed




2
up by the, by far, largest R&D budgets in the   standard for Single Source CT: the           patient radiation. With the SOMATOM
healthcare industry, has made Siemens the       SOMATOM Definition Edge with the revo-       Definition Edge, Siemens again pushes the
undisputed innovation leader in CT over         lutionary Stellar Detector with TrueSignal   boundaries of patient care.
the last 35 years. And our ambitious global     Technology. Developed with the clear goal
team continues to set the trend in an           of providing the latest in CT technology,
always changing environment, providing          the SOMATOM Definition Edge integrates
Answers for Life.                               the unique innovations of the SOMATOM
                                                Definition Flash into a groundbreaking
Our solution                                    Single Source CT system. Finally, Single
In 2008, Siemens introduced the gold            Source CT imaging can unleash its
standard in CT technology, still unrivaled      full potential: offering uncompromised
today: the SOMATOM® Definition Flash.           diagnostic outcome with highest image
And now, again, Siemens sets the                quality, acquired at impressively low




                                                                                                                                         3
SOMATOM Definition Edge
    The Reference in Single Source CT




4
See the Unseen					                                      09
Unprecedented spatial resolution	                        12
Uncompromised temporal resolution	                       14
Clinical field: Cardiovascular	                          16
Unparalleled acquisition speed		                         18
Clinical field: Acute care	                              20


Get More from Less	                                      23
Dose reduction in low-signal imaging	                    26
Dose reduction with SAFIRE	                              28
Dose reduction with CARE kV	                             30
Combined Applications to Reduce Exposure (CARE)	         32


Specify the Unspecific	                                  35
Calculi characterization in clinical routine	            38
Gout identification in clinical routine	                 40
Reducing metal artifacts in clinical routine	            42
Improved dynamic imaging in clinical routine	            44


Benefits and Technical Specifications 	                  46


International Version. Not for distribution in the US.




                                  Scan to see
                                  the unseen of
                                  Edge Technology
                                  features.


www.siemens.com/somatom-definition-edge


                                                              5
SOMATOM Definition Edge
    The Reference in Single Source CT




           See the unseen
           Get more from less
           Specify the unspecific




           For decades, Siemens has been the undisputed innovation leader in high-end CT
           imaging. But the clinical need for higher image quality persists. Therefore, we proudly
           introduce the SOMATOM Definition Edge with the revolutionary Stellar Detector,
           the first fully-integrated detector. Designed to minimize electronic noise, it takes
           CT imaging where it has never gone before.




6
The uniqueness of the Stellar Detector allows the SOMATOM Definition Edge
to generate ultra-thin slices, thus delivering the highest spatial resolution in CT.
You can visualize even the finest image details, for example, for the most
accurate stenosis and stent analysis. It lets you see what was previously unseen.
The minimized noise level of the Stellar Detector together with SAFIRE – our
raw-data-based iterative reconstruction – is perfect for ultra low-dose imaging,
eliminating the contradiction of outstanding image quality with minimal dose.
You get more diagnostic quality with less patient radiation.
Additionally, Dual Energy (DE) is a reality for Single Source CT imaging.
With the novel capabilities of the Stellar Detector and the only dose-optimized
Single Source DE scan mode, the SOMATOM Definition Edge enables you to
add tissue characteristics to the morphology. You can now specify formerly
unspecific information for higher diagnostic outcome.
With these unrivaled features, the SOMATOM Definition Edge enters new
frontiers in medical imaging, becoming: The Reference in Single Source CT.




                                                                                       7
Edge
Technology
See the Unseen
See the Unseen
                                         Introducing the latest generation of CT detector technology:
                                         Siemens’ unique Stellar Detector, together with innovative Edge
                                         Technology, delivers slices thinner than the detector spacing.




                                                            focal spot
                                                                                                                            The Stellar Detector
                  Edge Technology                                        A general principle in CT is that thinner slices   The Stellar Detector introduces the
     Minimized cross-talk from the                                       deliver more image detail, but also less light     next generation in detector technology,
         Stellar Detector creates an                                     quants per voxel, i.e., higher image noise.        succeeding gas and solid-state technology.
       almost perfect model of the
                                                                         This lowers the signal-to-noise ratio (SNR)        Using nanotechnology, it is possible to
     focal spot. The result is a slice
                thickness of 0.5 mm.
                                                                         and leads to slice blurring. Conventional CT       miniaturize the electronic components
                                                                         compensates by increasing dose. Clinical           on the detector elements, enabling their
        Conventional Technology                                          experience following the ALARA (As Low As          integration directly at the photodiode.
               Cross-talk resulting                                      Reasonably Achievable) principle has shown         So, for the first time, the electronics of
             from slice blurring in                                      that a 0.6 mm collimator width is the opti-        the detector elements are fully integrated
            conventional detector.                          detector
                                                                         mum combination of slice thickness and             in the photodiode. This full electronic
                                                            projection
                                                                         dose. So further reduction of slice thickness      integration is Siemens' revolutionary
                                                                         was limited. Until now.                            TrueSignal Technology.




10
Edge Technology
Electronic noise and cross-talk are mini-
mized thanks to full electronic integration.
Without cross-talk, intrinsic slice blurring
between neighboring detector rows can
be avoided and individual slice profiles
are much more precise. Siemens’ Edge
                                                                              Scan to learn
Technology creates an almost perfect model
                                                                              more about
of the focal spot and detector, generating
                                                                              the new
a slice thickness of 0.5 mm. Thanks to
                                                                              Stellar Detector.
minimized electronic noise, the 0.5 mm
slice has a sufficient signal contribution
to be used in clinical routine.
                                               www.siemens.com/edge-stellar




                                                                                                  11
0.30   mm



     Unprecedented
     spatial resolution

     Innovation delivers outstanding results            Increased image detail                          Higher signal-to-noise ratio
     High spatial resolution in combination             In addition to the Stellar Detector, the        But how can the reduced light quants of
     with a high signal-to-noise ratio (SNR) is a       SOMATOM Definition Edge is equipped with        a 0.5 mm slice be compensated for? The
     reliable indicator for excellent image quality.    Siemens’ renowned STRATON® tube with            secret is the TrueSignal Technology of the
     Together they describe the image detail level      z-Sharp™ Technology. This combination is        Stellar Detector. Instead of increasing dose,
     and sharpness that can be made visible while       the essence of increasing spatial resolution.   it makes more efficient use of the initially
     acquiring diagnostic CT images. In addition,       Using a flying focal spot with two distinct     available quants per voxel: As the electronic
     a homogenic slice profile with the same spa-       X-ray beams, z-Sharp acquires two individ-      noise of the detector is virtually eliminated,
     tial resolution and SNR everywhere in the          ual, overlapping slices. With Edge Technol-     the overall noise is reduced so that the quants
     entire Field of View (FOV) is essential for con-   ogy, the Stellar Detector now delivers slices   contribute to a higher SNR. Consequently,
     sistent high image quality. Other approaches       with a thickness of 0.5 mm, resulting in a      thin slices of 0.5 mm can be used in
     in the market had to make compromises, for         spatial resolution of up to 0.30 mm, which      clinical practice.
     example by reducing the FOV size.                  is equivalent to approximately 19 lp/cm.




12
More consistent image quality
By acquiring two distinct slices, z-Sharp
collects twice the amount of projections.
This avoids miscalculation of data points,
as they are measured and not interpolated,
providing a higher data quality. And as the
slices are acquired in parallel, the data points
are equidistant, resulting in a more consis-
tent slice thickness compared to conjugate
approaches. Adding the reduced slice blurring
of the Stellar Detector, the slice profile over-
all becomes more homogeneous with con-
sistent spatial resolution over the entire FoV.




                                                   13
142 msec



     Uncompromised
     temporal resolution

     Uncompromised rotation speed                                                                  Uncompromised performance
     The core technology to achieve high              noise. Until now, this typically had to be   The unique combination of Stellar Detector,
     rotation speed is the renowned STRATON           compensated for by increasing the applied    STRATON tube and new gantry is the key
     tube. Based on direct anode cooling, it          current which consequently required a        benefit of the SOMATOM Definition Edge.
     eliminates the need for heat storage and         higher generator power. But the Stellar      With a rotation speed of 0.28 sec, it delivers
     has an unmatched compact design.                 Detector with TrueSignal Technology          a temporal resolution of 142.5 msec. At the
     Together with new gantry architecture,           reduces electronic noise in the detector.    same time, it utilizes the unique spatial
     this enables an additional increase in the       This optimizes the initial SNR and thus      resolution of up to 0.30 mm provided by
     rotation speed of the SOMATOM Definition         avoids the need to further increase          the Stellar Detector. And its gantry concept
     Edge. Increased rotation speed means             generator power.                             now makes it possible to use it within the
     shorter rotation times. That means that the                                                   entire FoV of up to 500 mm. Only with this
     available signal per rotation is also reduced,                                                uncompromised performance can you
     which results in lower SNR or higher image                                                    achieve outstanding clinical results.




14
Uncompromised image detail
High temporal resolution is essential for
motion-artifact-free imaging, e.g., in cardiac
examinations to perform accurate stenosis
measurements. But this benefit is contra-
dicted when compromises like reduced
image detail or limited FoV have to be made
in order to utilize high rotation speeds.
Therefore, the SOMATOM Definition Edge
was specifically designed to go beyond
these limitations. Its revolutionary Stellar
Detector provides unprecedented image
detail independent of rotation speed.




                                                 15
Clinical field:
                                      Cardiovascular

                                      High spatial resolution                       High temporal resolution                        In-stent restenosis
  Cardiac imaging combines two        In cardiology, high spatial resolution only   Spatial resolution is of no benefit without     A common clinical question typically posed
        crucial requirements in CT    makes sense when it can be provided in        high temporal resolution. Limited spatial       in stent follow-up examinations is whether
 imaging: high spatial resolution     concert with high temporal resolution.        resolution can lead to motion artifacts from    the vessel has re-occluded after the stent
at high temporal resolution. One
                                      With only limited spatial resolution, the     the respective vessel. This increases the       has been set. As stents are very small
  example that demonstrates the
  benefits of the new SOMATOM
                                      visualization of small occlusions might be    danger of false positive findings, meaning      objects within constantly moving vessels,
        Definition Edge regarding     impaired, resulting in blurring artifacts.    a stenosis is diagnosed, although the           this procedure requires precise image details
   artifact-free high resolution is   These may affect the diagnosis, as it can     finding is a result of the misinterpreted       without motion artifacts. With the unique
      stent imaging in cardiology.    conceal the actual stenosis. With higher      fuzzy visualization of the vessel. Therefore,   combination of highest spatial resolution at
                                      spatial resolution, blurring artifacts are    high spatial resolution must be delivered       uncompromised temporal resolution, the
                                      reduced, allowing better assessment of        together with high temporal resolution;         SOMATOM Definition Edge offers the most
                                      the lumen.                                    not one or the other.                           advanced solution for this clinical challenge.




16
collimation:
128 x 0.5 mm
spatial resolution:
0.30 mm
temp resolution:
142 msec
scan time:
5 sec
scan length:
119 mm
rotation time:
0.28 sec
CTDIvol:
38 mGy
DLP:
656 mGy cm
eff. dose:
9.2 mSv




High resolution imaging of
stents at uncompromised
temporal resolutions allows
for sound exclusion of
in-stent stenosis.




                              17
230
                                                              mm / sec



     Unparalleled
     acquisition speed

                                               Uncompromised spatial resolution
          In conventional CT systems, high     One of the most challenging demands          In such cases the SOMATOM Definition
              resolution means scanning at     in CT is providing high acquisition speed    Edge is in a class of its own. The new level
                reduced pitch. With z-Sharp,   without compromising spatial resolution;     of image detail with a spatial resolution of
             high resolution is independent
                                               for example, in acute-care scenarios when    up to 0.30 mm provided by the Stellar
           of pitch, making high resolution
              available for high-pitch acute
                                               unconscious or uncooperative patients        Detector allows visualizations of even the
                         care examinations.    have to be scanned quickly. Here the         finest fractures or lesions. Additionally,
                                               ‘golden hour’ to diagnosis mandates          the newly designed gantry, together with
                                               precise localization and identification of   Siemens’ most advanced patient table,
                                               critical injuries. The goal is to prevent    now allows an acquisition speed of up to
                                               motion artifacts when patients have only     230 mm/sec. This takes motion out of
                                               a limited ability to hold their breath.      the equation, increasing the diagnostic
                                                                                            reliability in such crucial cases.




18
Conventional technology                                                        z-Sharp technology


                 R2        R1          R2     R1           R2 R1                                R1           R1            R1




                  pitch = 1.4         pitch = 1.0        pitch = 0.55                      pitch = 1.4   pitch = 1.0   pitch = 0.55




High-pitch high-resolution CT
Increasing spatial resolution beyond the            The uniqueness of the SOMATOM Definition
detector width requires overlapping slices.         Edge is the combination of the Stellar
For conventional CT systems, this means             Detector, the STRATON tube with z-Sharp,
reducing pitch to facilitate the slice overlap.     the new gantry with 0.28 sec rotation speed,
For scans requiring high pitch, the reduced         and the patient table that supports a pitch
or missing overlap then reduces spatial             of 1.7. This allows a scan speed of up to
resolution. But with z-Sharp, the overlap           230 mm/sec. Clinically, this means scanning
results from an acquisition with two distinct       the whole heart in half a second, a 50 cm
projections coming from the STRATON tube.           thorax in roughly two seconds or performing
Consequently, the two slices overlap inde-          a two-meter scan of the entire body in
pendently of the pitch used and can always          nearly eight-and-a-half seconds, all at a
provide highest resolution.                         spatial resolution of up to 0.30 mm.




                                                                                                                                      19
Clinical field:
                                      acute care

                                      The golden hour                                  High-resolution high-speed imaging
    Acute care is one of the most     Acute care demands the highest spatial           In addition to the fact that every second        whether very small fractures of the spine
   challenging applications in CT.    resolution at the fastest possible acquisition   counts in the golden hour, there is another      have impacted the spinal cord. So it is
This clinical field shows how the     speed, which is very challenging. The            reason to use the fastest possible acquisition   imperative to acquire the highest possible
 new SOMATOM Definition Edge
                                      reason is that the ‘golden hour’ is crucial:     speed. Acute-care patients are often             spatial resolution at the fastest possible
  is the answer when examining
an acute-care patient with severe
                                      Appropriate therapy which is instituted          uncooperative, so it is essential that the       acquisition speed. The SOMATOM Definition
       injuries of the upper spine.   within this time frame is likely to have a       CT scan is performed as fast as possible to      Edge with the unique STRATON tube makes
                                      much more significant impact on improving        reduce movement artifacts. But you want to       spatial resolution independent of the
                                      patient outcome by decreasing morbidity          be sure you are not reducing spatial resolu-     selected pitch. And having the patient table
                                      and mortality. Consequently, the guiding         tion. When looking at fractures, for example,    from the SOMATOM Definition Flash at
                                      imaging for these decisions must deliver the     it is essential to assess whether larger         a pitch of 1.7 is possible. This allows an
                                      required answers quickly. Therefore, CT is       fractures or broken bones have ruptured small    acquisition speed of up to 230 mm/sec at
                                      the modality of choice.                          vessels and caused internal bleeding, or         a spatial resolution of 0.30 mm.




20
collimation:
128 x 0.5 mm
spatial resolution:
0.30 mm
scan time:
7.6 sec
scan length:
230 mm
rotation time:
1.0 sec
CTDIvol:
22.4 mGy
DLP:
590 mGy cm
eff. dose:
8.9 mSv




Spine image of a 70-year-old
patient with vertebrae
degeneration visualizing even
the finest bone structures.




                                21
TrueSignal
Technology
Get More from Less
Get More from Less
     The unique Stellar Detector with TrueSignal Technology
     reflects the continuation of Siemens’ commitment to
     deliver best image quality at lowest signal or lowest dose.




                                                                                                    TrueSignal Technology
                         The low signal capability   There are various reasons to scan with         TrueSignal Technology with the full
                  of a detector can be described     low signals. For example, bariatric patients   integration of the Stellar Detector virtually
                  best by a high SNR. The Stellar    can cause strong attenuation. But low          eliminates electronic noise in the detector
                         Detector with TrueSignal
                                                     signals can be fully intentional, mainly       elements. The resulting SNR is increased so
                Techno­ogy minimizes electronic
                       l
                   noise – optimal for low signal
                                                     driven by the desire to reduce dose. Many      that even very low signals are sufficiently
                               and dose imaging.     recent innovations, especially iterative       strong enough for the detector to cope with.
                                                     reconstruction solutions, reflect this.        Low-signal images benefit from increased
                                                     They were explicitly developed to lower the    sharpness and clarity, as the detector can
                                                     applied dose. So it follows to introduce a     now differentiate the signal of an individual
                                                     detector that is specially optimized for       voxel much better than the surrounding
                                                     low-signal imaging: the Stellar Detector       image data.
                                                     with TrueSignal Technology.




24
SOMATOM                   noise
                Definition Edge           [HU]
                	   40 cm
                	   40 cm fit

                Conventional CT
                	   40 cm
                                    300
                	   40 cm fit                                             -25%         at 200 mA


                                                                                                   -20%     at 300 mA
                                    200

                                                                                                                        -12%     at 400 mA

                                    100




                                      0                                                                                                            current [mA]   Dose savings at the
                                                                                                                                                                  same noise level with
                                           0        50     100      150          200       250        300       350        400       450     500                  SOMATOM Definition Edge




Comparable noise level at lower signal
The outcome can be best visualized when           Due to minimized electronic noise, the
looking at noise measurements of large            available signal is less impaired, so that the
patients. When comparing conventional CT          same noise level can be achieved with
technology with the SOMATOM Definition            significantly lower signal levels. This means
Edge and the Stellar Detector with TrueSignal     that when there is high attenuation from
Technology, the resulting noise is more or        very large patients, the detector can make
less the same for high signals. But when          better use of the resulting low signal. Or,
the signal is lowered – either by high            the dose can be further reduced to achieve
attenuations from obese or broad-                 a comparable image quality.
shouldered patients, or by reducing the
applied mA – the impact of TrueSignal
Technology increases.




                                                                                                                                                                                            25
Up to


                                                                                                25%
                                      Dose reduction in
                                      low-signal imaging

                                      Obesity – the new global disease              Optimized bariatric imaging
  More and more patients suffer       One example of how reducing electronic        By minimizing electronic noise, the              State-of-the-art CT systems have to react
     from obesity. Therefore, the     noise with TrueSignal Technology benefits     detector’s SNR increases, providing much         to the new challenges presented by the
       capability to deliver sound    low-signal efficiency is bariatric imaging.   more flexibility in handling low signals. This   increasing number of bariatric patients. This
 bariatric imaging is essential for
                                      Obesity is on the rise: In the US and some    is essential for bariatric imaging, as often     means having the appropriate ergonomics
      state-of-the-art CT imaging.
                                      European countries, more than 1/3 of the      maximum power is applied, but the signal         to handle these patients, as well as having
                                      population is considered obese. Therefore,    reaching the detector is very low. Conven-       the technology to achieve the image quality
                                      there is a growing need to scan large         tional detectors have a comparatively high       necessary for reaching sound diagnoses.
                                      patients. However, obese patients attenuate   intrinsic noise level and impaired image         The SOMATOM Definition Edge delivers the
                                      a significant portion of the signal, so       quality. Due to the electronic integration of    ideal solution with a 78 cm gantry bore, and
                                      regardless of scanner ergonomics, many        the Stellar Detector, this noise level is        a table load capacity of more than 300 kg,
                                      conventional CT systems are unsuitable,       significantly lower, so the available signal     all enhanced by the new Stellar Detector
                                      as the signal is too low.                     can be processed more efficiently.               with TrueSignal Technology.




26
collimation:
64 x 0.6 mm
spatial resolution:
0.33 mm
scan time:
1.5 sec
scan length:
155 mm
rotation time:
0.5 sec
CTDIvol:
21 mGy
DLP:
325 mGy cm
eff. dose:
4.55 mSv




Conventional detector
technologies have difficulties
handling low signals, resulting,
for example, in streak artifacts
(left). With its higher SNR,
the Stellar Detector is perfectly
designed to cope with low
signals (right).




                                27
Up to


                                                                                                         60%
                                             Dose reduction
                                             with SAFIRE

                                             Low dose is low-signal imaging                  Iterative reconstruction                       SAFIRE and the Stellar Detector
* The following test method was used         The significant reduction of mA when scan-      After the initial reconstruction using         Superior image quality in regard to
   to determine a 60% dose reduction         ning with iterative reconstruction solutions    weighted filtered back projection (WFBP),      contrast and noise can be obtained with
                 when using the SAFIRE
         reconstruction software: Noise,     like SAFIRE (Sinogram Affirmed Iterative        the CT images are retransferred to raw data.   this methodology. And it can be used to
              CT numbers, homogeneity,       Reconstruction) also results in lower signals   By comparing this new synthetic raw data       initially acquire the data at lower mA and
      low-contrast resolution and high-      at the detector, so these examinations also     with the acquired data, differences can be     then compensate the image quality during
     contrast resolution were assessed
            in a Gammex 438 phantom.         benefit from the advantages of TrueSignal       identified by applying a dynamic raw-data      the reconstruction. By using this approach,
    Low-dose data reconstructed with         Technology. The computational power of          based noise model. An updated image is         SAFIRE enables a dose reduction of up to
        SAFIRE showed the same image         systems like FAST IRS fascilitate iterative     then reconstructed, with reduced image         60%.* This reduction in dose means a lower
    quality compared to full-dose data
         based on this test. Data on file.   reconstruction in a wider range of clinical     noise but without noticeable loss of sharp-    signal at the detector. So now unique low-
                                             applications. The number of iterative           ness. This is repeated several times – image   signal capabilities of the Stellar Detector
                                             reconstruction scans is thereby increased,      noise can be incrementally reduced and         further optimize the image quality, resulting
                                             resulting in more benefits for patients.        geometrical imperfections corrected.           in even higher sharpness and clarity.




28
collimation:
128 x 0.6 mm
spatial resolution:
0.33 mm
scan time:
11 sec
scan length:
245 mm
rotation time:
0.5 sec
CTDIvol:
8.5 mGy
DLP:
460 mGy cm
eff. dose:
6.9 mSv




Significantly improved image
quality at lower dose using
SAFIRE with the Stellar Detector
(right) compared to a regular
WFPB on a conventional
detector (left).




                              29
Up to


                                                                                               60%
                                    Dose reduction
                                    with CARE kV

                                    Real time dose modulation                      CNR optimized kV settings
         The main dose-relevant     In 1994, Siemens introduced CARE Dose4DTM      After the patient’s stature and the mAs, the    kV, and sets all other parameters accordingly
parameters for a CT scan are the    to actively modulate the applied power for     selected voltage (kV) is the third dose-        to get the defined CNR. Reducing the tube
    applied current and voltage,    scans, according to patients’ anatomy.         relevant value for a CT scan. Selecting the     voltage helps optimizing dose and improves
 depending on the examination
                                    CARE Dose4D aims to regulate mA in real        right kV settings is essential for achieving    image quality, e.g., for contrast-media
  type and the patient's habitus.
Only when taking all parameters
                                    time so that image quality is uniform across   optimal clinical outcome. CARE kV can auto-     enhanced examinations. With the new,
        into consideration, does    the whole scan range. But CT scanning is       matically suggest kV and effective mA to        improved STRATON tube, the voltage range
dose protection become compre-      not only adapting mA values: The right kV      optimize the contrast-to-noise ratio (CNR) of   is lowered to 70 kV. This, together with the
     hensive and patient-centric.   settings play an equal if not more important   the image, while limiting the applied dose.     unique CARE Child scan modes, helps further
                                    role in achieving optimum clinical outcome.    CARE kV takes the patient’s habitus from the    reduce the dose for pediatric or neonate
                                    Changing kV values also means adapting all     topogram and the chosen examination type        patients. With these features, an additional
                                    other values according to the respective       (non-contrast, bone, soft tissue, vascular)     dose reduction of up to 60% is possible.
                                    patient and examination type.                  into consideration, proposes the appropriate    Additionally, the system identifies bariatric




30
kV usage [%]




                                                     100
                                                       90
                                                                                                                         Without CARE kV
                                                       80

                                                       70
                                                       60
                                                                                                                         With CARE kV
                                                       50

                                                       40

                                                       30
                                                       20
                                                       10

                                                        0                                                                Tube voltage [kV]   Lower dose in 67% of patients
                                                                70         80         100        120       140                               with CARE kV




                                               Benefit for many patients
patients and sets the parameters accordingly   An evaluation of CARE kV with more than         30% came with no compromise in image
to make full use of the system’s reserves to   12,000 patients in the first months after its   quality; CNR could be maintained with
optimize CNR, and achieve the best image       introduction showed that there was a clear      no impact on workflow, as all system
quality possible for these patients.           shift towards 100 kV and 80 kV scans (see       parameters are automatically set.
                                               above). Dose could be saved in more than
                                               two thirds of these patients, compared to
                                               the initial protocols. And the dose reduction
                                               itself was significant. For example, regular
                                               abdomen scans could be reduced to below
                                               10 mGy using 100 kV, down from 14.1 mGy
                                               with the former standard protocol set at
                                               120 kV. This dose reduction of approximately




                                                                                                                                                                             31
Combined Applications
                                    to Reduce Exposure (CARE)

                                      Radiation
                                      exposure 9
                                                                                                                         Comprehensive dose protection
       Dose reduction lies at the     [mSv]                                               Dose reduction in cardiac CT   Following the ALARA principle, Siemens
   heart of the CARE philosophy.                8
                                                                                                                         introduced its CARE philosophy in the
  Each application is designed to              7                                                                         mid-1990s. The idea is to utilize every
contribute dose reduction during
                                               6                                                                         means available to reduce patient exposure.
   every step of the examination
 process resulting in an absolute
                                                                                                                         Siemens is the only vendor to offer a
                                               5
             minimum exposure.                                                                                           dose protection portfolio that comprehen-
                                               4                                                                         sively takes all relevant scan parameters
                                               3                                                                         into consideration and optimizes the
                                                                                                                         scan accordingly, from patient size to
                                               2
                                                                                                                         examination type, from mA to kV, and
                                               1                                                                         from scan preparation to data evaluation.
                                               0
                                                     Adaptive     CARE kV    CARE    MinDose    Adaptive     SAFIRE
                                                    ECG Pulsing             Dose4D             Dose Shield




32
collimation:
128 x 0.5 mm
spatial resolution:
0.30 mm
temp resolution:
142 msec
scan time:
5 sec
scan length:
119 mm
rotation time:
0.28 sec
CTDIvol:
7 mGy
DLP:
95 mGy cm
eff. dose:
1.33 mSv




Cardiac examinations are
amongst the most sensitive
when it comes to dose,
so combining all available
applications to reduce
exposure is key.




                             33
HiDynamics
Specify the Unspecific
Specify the Unspecific
                                        The TrueSignal Technology of the Stellar Detector brings yet another
                                        innovation: HiDynamics. Its unique, full dynamic range provides higher
                                        image sensitivity, especially for low-signal and low-energy scans.




                                                                                                     HiDynamics
 A larger dynamic range expands                                                                      Thanks to the full electronic integration of
 the detector’s sensitivity. As in a                                                                 the TrueSignal Technology, the Stellar
      backlit photo with a conven-                                                                   Detector can now utilize its full dynamic
 tional camera, the front regions
                                                                                                     range instead of having to switch bandwidth
turn black. But with higher sensi-
      tivity, details remain visible.     1st scan                   140 kV                          like conventional detectors. This unique
                                                                                                     feature is called HiDynamics. It increases the
                                                                                                     detector’s sensitivity at the respective energy
                                                                                                     level and allows for differentiation of
                                          2nd scan                   80 kV                           even the slightest signal changes, especially
                                                                                                     when scanning with very low kV levels.




36
Comparison of the 80 kV Dual
                                                                                                                                                Energy data set (left) with the
                                                                                                                                                140 kV Dual Energy data set
                                                                                                                                                (right) shows: almost identical
                                                                                                                                                image detail level in 80 kV due
                                                                                                                                                to the improvement resulting
                                                                                                                                                from HiDynamics.




The benefits of the Stellar Detector           Dose-optimized Single Source DE
The benefits of TrueSignal Technology and      When multiple scans of the same region          The scan mode consists of two successive
HiDynamics are also clear in functional        have to be performed, dose protection           spiral scans at different energy levels. In
imaging applications, such as Dual Energy,     becomes even more important in order to         order to avoid doubling the dose, both spi-
as well as in dynamic examinations. They       adhere to the ALARA principle. Therefore,       rals are performed at half the dose, so that
acquire multiple scans of the same region      it is imperative to exploit every possibility   there is no dose penalty for the resulting
to add functional information, such as         to reduce dose. Following this philosophy,      Dual Energy image. But, as it uses regular
tissue characteristics or perfusion data to    Siemens has introduced a Single Source          spirals, all dose reduction features can be
the morphology. In both cases, the scan        Dual Energy scan mode that utilizes all         utilized without limitations. The capabilities
modes acquire data at low kV. HiDynamics       dose-reduction functionalities without          of the Stellar Detector regarding low
significantly increases the detail level and   limitations: e.g., CARE Dose4D for real-time    dose / signal imaging represents the
sharpness of the images for these data sets.   mA modulation, or SAFIRE to reduce the          industry’s only Single Source Dual Energy
                                               mA created by iterative reconstruction.         scan mode optimized for low dose.




                                                                                                                                                                                  37
Calculi characterization
                                      in clinical routine

                                      Urinary stone disease
          Kidney stones are a good    Approximately 13% of men and 7% of            require intervention later. Current evidence    does not require intravenous contrast and
             example of how tissue    women in the United States will be            from the study “Urological Diseases in          covers the entire abdomen and pelvis. With
          characterization can lead   diagnosed with urinary stone disease in       America” suggests an increasing prevalence      this imaging modality, nearly all stone types
         to finding the appropriate
                                      their lives. Most stones are symptomatic      of urinary stone disease in the United          can be visualized. The essential benefit in
     therapy. Dual Energy informa-
      tion adds tissue information
                                      and cause pain, obstruction, and infection.   States. In addition, the likelihood of recur-   the diagnosis with Dual Energy CT is that
                 to the morphology.   They frequently require visits to the emer-   rence is estimated to be up to 50 % during      the stone type can be identified. With this
                                      gency room, hospitalization, mechanical       a five-year period. Thus, the diagnosis of      information at hand, the appropriate
                                      extraction or even surgical removal. Some     kidney stones has substantial impact with       treatment can be applied. For patients, this
                                      stones may be asymptomatic and are            respect to patient morbidity and healthcare     means that many interventional treatments
                                      only detected incidentally. However, even     budgets. The imaging modality of choice for     can be avoided, as it can be determined
                                      when stones are initially asymptomatic,       urinary stone disease is a low-dose, non-       upfront if a stone can be treated with
                                      symptoms may develop very quickly and         contrast CT scan. It is very easy to perform,   drugs or not.




38
collimation:
128 x 0.6 mm
spatial resolution:
0.33 mm
scan time:
1.3 sec
scan length:
117 mm
rotation time:
0.5 sec
CTDIvol:
5.28 + 3.02 mGy
(140 / 80 kV)
DLP:
80 + 40 mGy cm
(140 / 80 kV)
eff. dose:
1.8 mSv




Characterization with syngo
Single Source DE Kidney Stones
supports treatment decisions.




                             39
Gout identification in
                                      clinical routine

                                      Gout
     Gout is the most widespread      Gout is the most widespread form of            recurrent episodes. The classic symptoms         duced by the disease is directly verified,
form of crystal arthropathy and a     crystal arthropathy and the most common        of gout are painful, visibly swollen             confirming the definite diagnosis of gout.
     common inflammatory joint        inflammatory joint disease in men. It is       peripheral joints. However, gout is difficult    The benefit for patients is not only that
disease. However, gout is difficult
                                      caused by the deposition of uric acid          to diagnose, as there are various forms of       the painful puncture in a conventional
    to diagnose. Dual Energy can
   detect gout in regions that are
                                      crystals in joints. Up to 1 in 200 people in   arthritis that have similar symptoms. With       examination can be avoided, but also
                 often overlooked.    the western world, 2.1 million people in the   Dual Energy CT and syngo® Dual Energy            that the risk of false negative outcomes
                                      US, and some 1.5 million people in Germany     Gout, a non-invasive assessment of gout is       is reduced in cases where the puncture
                                      are currently afflicted by this painful,       feasible. The algorithm color codes different    misses the respective tissue.
                                      destructive disease. Furthermore, due to our   attenuation values at different energy levels
                                      eating habits, these figures are constantly    so that the uric acid crystals are color coded
                                      increasing. Gout can affect numerous joints    in red, while calcium and bone formations
                                      throughout the body, especially during         are displayed in blue. Thus, uric acid pro-




40
collimation:
128 x 0.6 mm
spatial resolution:
0.33 mm
scan time:
4 sec
scan length:
181 mm
rotation time:
0.5 sec
CTDIvol:
3.32 + 4.46 mGy
(140 / 80 kV)
DLP:
71 + 95 mGy cm
(140 / 80 kV)
eff. dose:
0.13 mSv




Clear identification with syngo
Single Source DE Gout avoids
false negative diagnosis of
conventional procedures.




                              41
Reducing metal
                                       artifacts in clinical routine

                                       Metal artifact reduction with Dual Energy
       Metal artifacts pose severe     A big challenge in CT imaging is the impact       artifact free as possible. For example, when    And syngo Dual Energy Monoenergetic
        difficulties in CT imaging     of metal objects on image quality. Due to         assessing organs in the pelvic region, images   Imaging enables the minimization of metal
     due to the resulting artifacts.   the high attenuation of metal compared to         are often impaired if the patient has a hip     artifacts by specifically selecting the respec-
       Single Source Dual Energy
                                       the surrounding tissue, images can suffer         prosthesis. The high attenuation of this mas-   tive kV level at which the metal objects have
          now delivers a solution.
                                       from streaks or even shadows around               sive metal object causes adjoining regions      least impact on image quality. With this
                                       the metal objects. The cause for this is          to suffer from very low signals. Until now,     unique combination, implants, clamps or
                                       so-called ‘beam starvation.’ Typical metal        these artifacts could not be compensated        screws can be ideally dealt with in order to
                                       artifacts result from implants, e.g., in teeth,   for. But now, two solutions come together:      obtain the highest diagnostic outcome.
                                       or when clamps and screws are used in             The unique Stellar Detector in the
                                       invasive treatments. But when it comes to         SOMATOM Definition Edge is specifically
                                       treatment decisions or treatment follow-up,       optimized to handle low signals with its
                                       it is essential that the image is as              TrueSignal Technology and HiDynamics.




42
collimation:
128 x 0.6 mm
spatial resolution:
0.33 mm
scan time:
5 sec
scan length:
228 mm
rotation time:
0.5 sec
CTDIvol:
12.31 + 4.46 mGy
(140 / 80 kV)
DLP:
380 + 129 mGy cm
(140 / 80 kV)
eff. dose:
7.64 mSv




Significant reduction of metal
artifacts from hip implant with
syngo Single Source DE Monoen-
ergetic delivers much higher
diagnostic image quality




                            43
Improved dynamic
                                     imaging in clinical routine

                                                                                     Adaptive 4D Spiral and HiDynamics
        Perfusion information is     Stroke is one of the three most frequent        With the Adaptive 4D Spiral, Siemens has        Spiral are specifically set to this length
   crucial in many clinical fields   causes of death worldwide. The diagnosis        introduced a scan mode that performs per-       for stroke evaluations. In addition, the
         such as stroke or tumor     and treatment of stroke cases is a clinical     fusion evaluations beyond the limitations of    SOMATOM Definition Edge, with the Stellar
  assessments. The Adaptive 4D
                                     field in which time is of the essence – or      a static detector. By applying a continuously   Detector and HiDynamics, is the perfect
   Spiral is key to making these
exams ready for clinical practice.
                                     where ‘time is brain,’ meaning that the right   repeated bi-directional, smooth table           choice for better differentiation of the
                                     decisions have to be made ideally within the    movement over the desired scan range,           perfusion level, as brain perfusion studies
                                     first hours after the first symptoms have       a perfusion assessment covering a region        are typically performed at 80 kV. Regardless
                                     occurred. Consequently, it is essential that    of up to 15 cm can be performed. Recent         of cause – from infarctions due to stroke
                                     the diagnostic information is delivered         publications have shown that a scan range       and extensive bleeding, to subarachnoid
                                     quickly, reliably, and accurately, and gives    of approximately 10 cm is ideal to assess       hemorrhage or a ruptured aneurysm – 
                                     a comprehensive overview about the status       brain perfusion. Consequently, the neuro        seeing clearly makes a crucial difference
                                     of the disease.                                 perfusion scan modes with the Adaptive 4D       in determining treatment.




44
collimation:
128 x 0.6 mm
scan time:
45 sec
scan length:
100 mm
rotation time:
0.285 sec
CTDIvol:
260 mGy
DLP:
3069 mGy cm
eff. dose:
6.4 mSv




Comprehensive perfusion
evaluation with syngo VPCT
Neuro delivers crucial
information regarding tissue
at risk after a stroke.




                               45
SOMATOM Definition Edge
     The Reference in Single Source CT


     See the unseen
     Edge Technology – The
     reference in image quality
     • Unprecedented spatial resolution
     • Uncompromised temporal resolution
     •  nparalleled acquisition speed
       U

     Get more from less
     TrueSignal Technology – The
     reference in dose efficiency
     • Optimized low-signal imaging
     •  ptimized low-dose imaging
       O
     •  ptimized patient-centric imaging
       O

     Specify the unspecific
     HiDynamics – The reference
     in functional imaging
     • Routine ready Single Source Dual Energy
     • Routine ready metal artifact reduction
     • Routine ready dynamic imaging




46
Technical Specifications
• 	Stellar Detector with TrueSignal Technology
• 	256 x 0.5 mm slices and 0.30 mm spatial
   resolution with Edge Technology
• 	Dose-optimized Single Source Dual Energy
   and HiDynamics
• 	128-slice acquisition with STRATON tube
   and z-Sharp Technology
• 	Up to 384-slice reconstruction
• 	0.28 sec rotation time with
   142.5 sec temporal resolution
• 	1.7 maximum pitch with
   230 mm/sec acquisition speed
• 	Patient table: 227 kg capacity
   (300 kg optional), 200 cm scan range
• 	With up to 60 fps FBP and
   20 fps SAFIRE reconstruction speed
• 	4D scan range: 15 cm for perfusion,
   48 cm for CTA imaging with
   Adaptive 4D Spiral
• 	Reduced energy consumption by up to
   20% in system stand-by with the
   Stellar Detector




                                                 47
In the event that upgrades require FDA approval,            SOMATOM Definition Edge is under development,
Siemens cannot predict whether or when the FDA will         and is not commercially available in the US.
issue its approval. Therefore, if regulatory clearance
                                                            The information about SAFIRE (Sinogram Affirmed
is obtained and is applicable to this package, it will be
                                                            Iterative Reconstruction) is being provided for planning
made available according to the terms of this offer.
                                                            purposes. The product is pending 510(k) review, and is
On account of certain regional limitations of sales         not yet commercially available in the US. In clinical
rights and service availability, we cannot guarantee        practice, the use of SAFIRE may reduce CT patient dose
that all products included in this brochure are available   depending on the clinical task, patient size, anatomical
through the Siemens sales organization worldwide.           location, and clinical practice. A consultation with a
Availability and packaging may vary by country and is       radiologist and a physicist should be made to deter-
subject to change without prior notice. Some/all of the     mine the appropriate dose to obtain diagnostic image
features and products described herein may not be           quality for the particular clinical task.
available in the United States.
The information in this document contains general
technical descriptions of specifications and options as
well as standard and optional features which do not         Courtesy list                                              Global Business Unit
always have to be present in individual cases.              Department of Radiology, University of Erlangen, Germany   Siemens AG
                                                            Mayo Clinic, Rochester (Minnesota), USA                    Medical Solutions
Siemens reserves the right to modify the design,
                                                            Nan Xi Shan Hospit al / Guilin, P.R. China                 Computed Tomography
packaging, specifications, and options described herein
                                                            Beihua University 1st Hospital / Jilin, P.R. China          Radiation Oncology
without prior notice. Please contact your local Siemens
                                                                                                                       Siemensstr. 1
sales representative for the most current information.
                                                                                                                       DE-91301 Forchheim
Note: Any technical data contained in this document                                                                    Germany
may vary within defined tolerances. Original images         Order No. A91CT-04015-51C1-7600 | Printed in Germany       Phone: +49 9191 18 0
always lose a certain amount of detail when reproduced.     CC CT WS 11111.5 | © 11.2011, Siemens AG                   Fax: +49 9191 18 9998




Global Siemens Headquarters                                 Global Siemens Healthcare ­ eadquarters
                                                                                      H                                Legal Manufacturer
Siemens AG                                                  Siemens AG
                                                                                                                       Siemens AG
Wittelsbacherplatz 2                                        Healthcare Sector
                                                                                                                       Wittelsbacherplatz 2
80333 Muenchen                                              Henkestrasse 127
                                                                                                                       DE-80333 Muenchen
Germany                                                     91052 Erlangen                                             Germany
                                                            Germany
                                                            Phone: +49 9131 84 0
                                                            www.siemens.com/healthcare

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Somatom Definition Edge -SIEMENS

  • 1. www.siemens.com/somatom-definition-edge The Reference in Single Source CT SOMATOM Definition Edge Answers for life.
  • 3. Siemens CT Vision Today’s reality Our approach • to maximize workflow efficiency Better healthcare for all patients is a key In order to meet our share of responsibility • to make state-of-the-art CT affordable priority for the entire medical industry. in addressing these challenges, Siemens, • to set the standard in customer care But the realities of clinical practice often from the earliest stages of research, product make this simple-to-understand goal quite development, and design, relies upon the Our vision difficult to realize: staying within budgets, advice and recommendations of external As a partner to our customers, we create reducing hospital stays, speeding up time to medical experts to determine our focus –  CT innovations that lift clinical practice to diagnosis, and dealing with personnel issues, and this focus has been on the needs and the next level of excellence and enable wide while maintaining high clinical standards demands of our end users. Over the years, access to better patient care. We believe and throughput. At the same time, patients this focus has been fine-tuned in four that even the farthest technical horizons demand better and faster results. key areas: are temporary and can be surpassed • to lead technological and medical with consistent dedication to improved advancement healthcare. This visionary approach, backed 2
  • 4. up by the, by far, largest R&D budgets in the standard for Single Source CT: the patient radiation. With the SOMATOM healthcare industry, has made Siemens the SOMATOM Definition Edge with the revo- Definition Edge, Siemens again pushes the undisputed innovation leader in CT over lutionary Stellar Detector with TrueSignal boundaries of patient care. the last 35 years. And our ambitious global Technology. Developed with the clear goal team continues to set the trend in an of providing the latest in CT technology, always changing environment, providing the SOMATOM Definition Edge integrates Answers for Life. the unique innovations of the SOMATOM Definition Flash into a groundbreaking Our solution Single Source CT system. Finally, Single In 2008, Siemens introduced the gold Source CT imaging can unleash its standard in CT technology, still unrivaled full potential: offering uncompromised today: the SOMATOM® Definition Flash. diagnostic outcome with highest image And now, again, Siemens sets the quality, acquired at impressively low 3
  • 5. SOMATOM Definition Edge The Reference in Single Source CT 4
  • 6. See the Unseen 09 Unprecedented spatial resolution 12 Uncompromised temporal resolution 14 Clinical field: Cardiovascular 16 Unparalleled acquisition speed 18 Clinical field: Acute care 20 Get More from Less 23 Dose reduction in low-signal imaging 26 Dose reduction with SAFIRE 28 Dose reduction with CARE kV 30 Combined Applications to Reduce Exposure (CARE) 32 Specify the Unspecific 35 Calculi characterization in clinical routine 38 Gout identification in clinical routine 40 Reducing metal artifacts in clinical routine 42 Improved dynamic imaging in clinical routine 44 Benefits and Technical Specifications 46 International Version. Not for distribution in the US. Scan to see the unseen of Edge Technology features. www.siemens.com/somatom-definition-edge 5
  • 7. SOMATOM Definition Edge The Reference in Single Source CT See the unseen Get more from less Specify the unspecific For decades, Siemens has been the undisputed innovation leader in high-end CT imaging. But the clinical need for higher image quality persists. Therefore, we proudly introduce the SOMATOM Definition Edge with the revolutionary Stellar Detector, the first fully-integrated detector. Designed to minimize electronic noise, it takes CT imaging where it has never gone before. 6
  • 8. The uniqueness of the Stellar Detector allows the SOMATOM Definition Edge to generate ultra-thin slices, thus delivering the highest spatial resolution in CT. You can visualize even the finest image details, for example, for the most accurate stenosis and stent analysis. It lets you see what was previously unseen. The minimized noise level of the Stellar Detector together with SAFIRE – our raw-data-based iterative reconstruction – is perfect for ultra low-dose imaging, eliminating the contradiction of outstanding image quality with minimal dose. You get more diagnostic quality with less patient radiation. Additionally, Dual Energy (DE) is a reality for Single Source CT imaging. With the novel capabilities of the Stellar Detector and the only dose-optimized Single Source DE scan mode, the SOMATOM Definition Edge enables you to add tissue characteristics to the morphology. You can now specify formerly unspecific information for higher diagnostic outcome. With these unrivaled features, the SOMATOM Definition Edge enters new frontiers in medical imaging, becoming: The Reference in Single Source CT. 7
  • 11. See the Unseen Introducing the latest generation of CT detector technology: Siemens’ unique Stellar Detector, together with innovative Edge Technology, delivers slices thinner than the detector spacing. focal spot The Stellar Detector Edge Technology A general principle in CT is that thinner slices The Stellar Detector introduces the Minimized cross-talk from the deliver more image detail, but also less light next generation in detector technology, Stellar Detector creates an quants per voxel, i.e., higher image noise. succeeding gas and solid-state technology. almost perfect model of the This lowers the signal-to-noise ratio (SNR) Using nanotechnology, it is possible to focal spot. The result is a slice thickness of 0.5 mm. and leads to slice blurring. Conventional CT miniaturize the electronic components compensates by increasing dose. Clinical on the detector elements, enabling their Conventional Technology experience following the ALARA (As Low As integration directly at the photodiode. Cross-talk resulting Reasonably Achievable) principle has shown So, for the first time, the electronics of from slice blurring in that a 0.6 mm collimator width is the opti- the detector elements are fully integrated conventional detector. detector mum combination of slice thickness and in the photodiode. This full electronic projection dose. So further reduction of slice thickness integration is Siemens' revolutionary was limited. Until now. TrueSignal Technology. 10
  • 12. Edge Technology Electronic noise and cross-talk are mini- mized thanks to full electronic integration. Without cross-talk, intrinsic slice blurring between neighboring detector rows can be avoided and individual slice profiles are much more precise. Siemens’ Edge Scan to learn Technology creates an almost perfect model more about of the focal spot and detector, generating the new a slice thickness of 0.5 mm. Thanks to Stellar Detector. minimized electronic noise, the 0.5 mm slice has a sufficient signal contribution to be used in clinical routine. www.siemens.com/edge-stellar 11
  • 13. 0.30 mm Unprecedented spatial resolution Innovation delivers outstanding results Increased image detail Higher signal-to-noise ratio High spatial resolution in combination In addition to the Stellar Detector, the But how can the reduced light quants of with a high signal-to-noise ratio (SNR) is a SOMATOM Definition Edge is equipped with a 0.5 mm slice be compensated for? The reliable indicator for excellent image quality. Siemens’ renowned STRATON® tube with secret is the TrueSignal Technology of the Together they describe the image detail level z-Sharp™ Technology. This combination is Stellar Detector. Instead of increasing dose, and sharpness that can be made visible while the essence of increasing spatial resolution. it makes more efficient use of the initially acquiring diagnostic CT images. In addition, Using a flying focal spot with two distinct available quants per voxel: As the electronic a homogenic slice profile with the same spa- X-ray beams, z-Sharp acquires two individ- noise of the detector is virtually eliminated, tial resolution and SNR everywhere in the ual, overlapping slices. With Edge Technol- the overall noise is reduced so that the quants entire Field of View (FOV) is essential for con- ogy, the Stellar Detector now delivers slices contribute to a higher SNR. Consequently, sistent high image quality. Other approaches with a thickness of 0.5 mm, resulting in a thin slices of 0.5 mm can be used in in the market had to make compromises, for spatial resolution of up to 0.30 mm, which clinical practice. example by reducing the FOV size. is equivalent to approximately 19 lp/cm. 12
  • 14. More consistent image quality By acquiring two distinct slices, z-Sharp collects twice the amount of projections. This avoids miscalculation of data points, as they are measured and not interpolated, providing a higher data quality. And as the slices are acquired in parallel, the data points are equidistant, resulting in a more consis- tent slice thickness compared to conjugate approaches. Adding the reduced slice blurring of the Stellar Detector, the slice profile over- all becomes more homogeneous with con- sistent spatial resolution over the entire FoV. 13
  • 15. 142 msec Uncompromised temporal resolution Uncompromised rotation speed Uncompromised performance The core technology to achieve high noise. Until now, this typically had to be The unique combination of Stellar Detector, rotation speed is the renowned STRATON compensated for by increasing the applied STRATON tube and new gantry is the key tube. Based on direct anode cooling, it current which consequently required a benefit of the SOMATOM Definition Edge. eliminates the need for heat storage and higher generator power. But the Stellar With a rotation speed of 0.28 sec, it delivers has an unmatched compact design. Detector with TrueSignal Technology a temporal resolution of 142.5 msec. At the Together with new gantry architecture, reduces electronic noise in the detector. same time, it utilizes the unique spatial this enables an additional increase in the This optimizes the initial SNR and thus resolution of up to 0.30 mm provided by rotation speed of the SOMATOM Definition avoids the need to further increase the Stellar Detector. And its gantry concept Edge. Increased rotation speed means generator power. now makes it possible to use it within the shorter rotation times. That means that the entire FoV of up to 500 mm. Only with this available signal per rotation is also reduced, uncompromised performance can you which results in lower SNR or higher image achieve outstanding clinical results. 14
  • 16. Uncompromised image detail High temporal resolution is essential for motion-artifact-free imaging, e.g., in cardiac examinations to perform accurate stenosis measurements. But this benefit is contra- dicted when compromises like reduced image detail or limited FoV have to be made in order to utilize high rotation speeds. Therefore, the SOMATOM Definition Edge was specifically designed to go beyond these limitations. Its revolutionary Stellar Detector provides unprecedented image detail independent of rotation speed. 15
  • 17. Clinical field: Cardiovascular High spatial resolution High temporal resolution In-stent restenosis Cardiac imaging combines two In cardiology, high spatial resolution only Spatial resolution is of no benefit without A common clinical question typically posed crucial requirements in CT makes sense when it can be provided in high temporal resolution. Limited spatial in stent follow-up examinations is whether imaging: high spatial resolution concert with high temporal resolution. resolution can lead to motion artifacts from the vessel has re-occluded after the stent at high temporal resolution. One With only limited spatial resolution, the the respective vessel. This increases the has been set. As stents are very small example that demonstrates the benefits of the new SOMATOM visualization of small occlusions might be danger of false positive findings, meaning objects within constantly moving vessels, Definition Edge regarding impaired, resulting in blurring artifacts. a stenosis is diagnosed, although the this procedure requires precise image details artifact-free high resolution is These may affect the diagnosis, as it can finding is a result of the misinterpreted without motion artifacts. With the unique stent imaging in cardiology. conceal the actual stenosis. With higher fuzzy visualization of the vessel. Therefore, combination of highest spatial resolution at spatial resolution, blurring artifacts are high spatial resolution must be delivered uncompromised temporal resolution, the reduced, allowing better assessment of together with high temporal resolution; SOMATOM Definition Edge offers the most the lumen. not one or the other. advanced solution for this clinical challenge. 16
  • 18. collimation: 128 x 0.5 mm spatial resolution: 0.30 mm temp resolution: 142 msec scan time: 5 sec scan length: 119 mm rotation time: 0.28 sec CTDIvol: 38 mGy DLP: 656 mGy cm eff. dose: 9.2 mSv High resolution imaging of stents at uncompromised temporal resolutions allows for sound exclusion of in-stent stenosis. 17
  • 19. 230   mm / sec Unparalleled acquisition speed Uncompromised spatial resolution In conventional CT systems, high One of the most challenging demands In such cases the SOMATOM Definition resolution means scanning at in CT is providing high acquisition speed Edge is in a class of its own. The new level reduced pitch. With z-Sharp, without compromising spatial resolution; of image detail with a spatial resolution of high resolution is independent for example, in acute-care scenarios when up to 0.30 mm provided by the Stellar of pitch, making high resolution available for high-pitch acute unconscious or uncooperative patients Detector allows visualizations of even the care examinations. have to be scanned quickly. Here the finest fractures or lesions. Additionally, ‘golden hour’ to diagnosis mandates the newly designed gantry, together with precise localization and identification of Siemens’ most advanced patient table, critical injuries. The goal is to prevent now allows an acquisition speed of up to motion artifacts when patients have only 230 mm/sec. This takes motion out of a limited ability to hold their breath. the equation, increasing the diagnostic reliability in such crucial cases. 18
  • 20. Conventional technology z-Sharp technology R2 R1 R2 R1 R2 R1 R1 R1 R1 pitch = 1.4 pitch = 1.0 pitch = 0.55 pitch = 1.4 pitch = 1.0 pitch = 0.55 High-pitch high-resolution CT Increasing spatial resolution beyond the The uniqueness of the SOMATOM Definition detector width requires overlapping slices. Edge is the combination of the Stellar For conventional CT systems, this means Detector, the STRATON tube with z-Sharp, reducing pitch to facilitate the slice overlap. the new gantry with 0.28 sec rotation speed, For scans requiring high pitch, the reduced and the patient table that supports a pitch or missing overlap then reduces spatial of 1.7. This allows a scan speed of up to resolution. But with z-Sharp, the overlap 230 mm/sec. Clinically, this means scanning results from an acquisition with two distinct the whole heart in half a second, a 50 cm projections coming from the STRATON tube. thorax in roughly two seconds or performing Consequently, the two slices overlap inde- a two-meter scan of the entire body in pendently of the pitch used and can always nearly eight-and-a-half seconds, all at a provide highest resolution. spatial resolution of up to 0.30 mm. 19
  • 21. Clinical field: acute care The golden hour High-resolution high-speed imaging Acute care is one of the most Acute care demands the highest spatial In addition to the fact that every second whether very small fractures of the spine challenging applications in CT. resolution at the fastest possible acquisition counts in the golden hour, there is another have impacted the spinal cord. So it is This clinical field shows how the speed, which is very challenging. The reason to use the fastest possible acquisition imperative to acquire the highest possible new SOMATOM Definition Edge reason is that the ‘golden hour’ is crucial: speed. Acute-care patients are often spatial resolution at the fastest possible is the answer when examining an acute-care patient with severe Appropriate therapy which is instituted uncooperative, so it is essential that the acquisition speed. The SOMATOM Definition injuries of the upper spine. within this time frame is likely to have a CT scan is performed as fast as possible to Edge with the unique STRATON tube makes much more significant impact on improving reduce movement artifacts. But you want to spatial resolution independent of the patient outcome by decreasing morbidity be sure you are not reducing spatial resolu- selected pitch. And having the patient table and mortality. Consequently, the guiding tion. When looking at fractures, for example, from the SOMATOM Definition Flash at imaging for these decisions must deliver the it is essential to assess whether larger a pitch of 1.7 is possible. This allows an required answers quickly. Therefore, CT is fractures or broken bones have ruptured small acquisition speed of up to 230 mm/sec at the modality of choice. vessels and caused internal bleeding, or a spatial resolution of 0.30 mm. 20
  • 22. collimation: 128 x 0.5 mm spatial resolution: 0.30 mm scan time: 7.6 sec scan length: 230 mm rotation time: 1.0 sec CTDIvol: 22.4 mGy DLP: 590 mGy cm eff. dose: 8.9 mSv Spine image of a 70-year-old patient with vertebrae degeneration visualizing even the finest bone structures. 21
  • 25. Get More from Less The unique Stellar Detector with TrueSignal Technology reflects the continuation of Siemens’ commitment to deliver best image quality at lowest signal or lowest dose. TrueSignal Technology The low signal capability There are various reasons to scan with TrueSignal Technology with the full of a detector can be described low signals. For example, bariatric patients integration of the Stellar Detector virtually best by a high SNR. The Stellar can cause strong attenuation. But low eliminates electronic noise in the detector Detector with TrueSignal signals can be fully intentional, mainly elements. The resulting SNR is increased so Techno­ogy minimizes electronic l noise – optimal for low signal driven by the desire to reduce dose. Many that even very low signals are sufficiently and dose imaging. recent innovations, especially iterative strong enough for the detector to cope with. reconstruction solutions, reflect this. Low-signal images benefit from increased They were explicitly developed to lower the sharpness and clarity, as the detector can applied dose. So it follows to introduce a now differentiate the signal of an individual detector that is specially optimized for voxel much better than the surrounding low-signal imaging: the Stellar Detector image data. with TrueSignal Technology. 24
  • 26. SOMATOM noise Definition Edge [HU] 40 cm 40 cm fit Conventional CT 40 cm 300 40 cm fit -25% at 200 mA -20% at 300 mA 200 -12% at 400 mA 100 0 current [mA] Dose savings at the same noise level with 0 50 100 150 200 250 300 350 400 450 500 SOMATOM Definition Edge Comparable noise level at lower signal The outcome can be best visualized when Due to minimized electronic noise, the looking at noise measurements of large available signal is less impaired, so that the patients. When comparing conventional CT same noise level can be achieved with technology with the SOMATOM Definition significantly lower signal levels. This means Edge and the Stellar Detector with TrueSignal that when there is high attenuation from Technology, the resulting noise is more or very large patients, the detector can make less the same for high signals. But when better use of the resulting low signal. Or, the signal is lowered – either by high the dose can be further reduced to achieve attenuations from obese or broad- a comparable image quality. shouldered patients, or by reducing the applied mA – the impact of TrueSignal Technology increases. 25
  • 27. Up to 25% Dose reduction in low-signal imaging Obesity – the new global disease Optimized bariatric imaging More and more patients suffer One example of how reducing electronic By minimizing electronic noise, the State-of-the-art CT systems have to react from obesity. Therefore, the noise with TrueSignal Technology benefits detector’s SNR increases, providing much to the new challenges presented by the capability to deliver sound low-signal efficiency is bariatric imaging. more flexibility in handling low signals. This increasing number of bariatric patients. This bariatric imaging is essential for Obesity is on the rise: In the US and some is essential for bariatric imaging, as often means having the appropriate ergonomics state-of-the-art CT imaging. European countries, more than 1/3 of the maximum power is applied, but the signal to handle these patients, as well as having population is considered obese. Therefore, reaching the detector is very low. Conven- the technology to achieve the image quality there is a growing need to scan large tional detectors have a comparatively high necessary for reaching sound diagnoses. patients. However, obese patients attenuate intrinsic noise level and impaired image The SOMATOM Definition Edge delivers the a significant portion of the signal, so quality. Due to the electronic integration of ideal solution with a 78 cm gantry bore, and regardless of scanner ergonomics, many the Stellar Detector, this noise level is a table load capacity of more than 300 kg, conventional CT systems are unsuitable, significantly lower, so the available signal all enhanced by the new Stellar Detector as the signal is too low. can be processed more efficiently. with TrueSignal Technology. 26
  • 28. collimation: 64 x 0.6 mm spatial resolution: 0.33 mm scan time: 1.5 sec scan length: 155 mm rotation time: 0.5 sec CTDIvol: 21 mGy DLP: 325 mGy cm eff. dose: 4.55 mSv Conventional detector technologies have difficulties handling low signals, resulting, for example, in streak artifacts (left). With its higher SNR, the Stellar Detector is perfectly designed to cope with low signals (right). 27
  • 29. Up to 60% Dose reduction with SAFIRE Low dose is low-signal imaging Iterative reconstruction SAFIRE and the Stellar Detector * The following test method was used The significant reduction of mA when scan- After the initial reconstruction using Superior image quality in regard to to determine a 60% dose reduction ning with iterative reconstruction solutions weighted filtered back projection (WFBP), contrast and noise can be obtained with when using the SAFIRE reconstruction software: Noise, like SAFIRE (Sinogram Affirmed Iterative the CT images are retransferred to raw data. this methodology. And it can be used to CT numbers, homogeneity, Reconstruction) also results in lower signals By comparing this new synthetic raw data initially acquire the data at lower mA and low-contrast resolution and high- at the detector, so these examinations also with the acquired data, differences can be then compensate the image quality during contrast resolution were assessed in a Gammex 438 phantom. benefit from the advantages of TrueSignal identified by applying a dynamic raw-data the reconstruction. By using this approach, Low-dose data reconstructed with Technology. The computational power of based noise model. An updated image is SAFIRE enables a dose reduction of up to SAFIRE showed the same image systems like FAST IRS fascilitate iterative then reconstructed, with reduced image 60%.* This reduction in dose means a lower quality compared to full-dose data based on this test. Data on file. reconstruction in a wider range of clinical noise but without noticeable loss of sharp- signal at the detector. So now unique low- applications. The number of iterative ness. This is repeated several times – image signal capabilities of the Stellar Detector reconstruction scans is thereby increased, noise can be incrementally reduced and further optimize the image quality, resulting resulting in more benefits for patients. geometrical imperfections corrected. in even higher sharpness and clarity. 28
  • 30. collimation: 128 x 0.6 mm spatial resolution: 0.33 mm scan time: 11 sec scan length: 245 mm rotation time: 0.5 sec CTDIvol: 8.5 mGy DLP: 460 mGy cm eff. dose: 6.9 mSv Significantly improved image quality at lower dose using SAFIRE with the Stellar Detector (right) compared to a regular WFPB on a conventional detector (left). 29
  • 31. Up to 60% Dose reduction with CARE kV Real time dose modulation CNR optimized kV settings The main dose-relevant In 1994, Siemens introduced CARE Dose4DTM After the patient’s stature and the mAs, the kV, and sets all other parameters accordingly parameters for a CT scan are the to actively modulate the applied power for selected voltage (kV) is the third dose- to get the defined CNR. Reducing the tube applied current and voltage, scans, according to patients’ anatomy. relevant value for a CT scan. Selecting the voltage helps optimizing dose and improves depending on the examination CARE Dose4D aims to regulate mA in real right kV settings is essential for achieving image quality, e.g., for contrast-media type and the patient's habitus. Only when taking all parameters time so that image quality is uniform across optimal clinical outcome. CARE kV can auto- enhanced examinations. With the new, into consideration, does the whole scan range. But CT scanning is matically suggest kV and effective mA to improved STRATON tube, the voltage range dose protection become compre- not only adapting mA values: The right kV optimize the contrast-to-noise ratio (CNR) of is lowered to 70 kV. This, together with the hensive and patient-centric. settings play an equal if not more important the image, while limiting the applied dose. unique CARE Child scan modes, helps further role in achieving optimum clinical outcome. CARE kV takes the patient’s habitus from the reduce the dose for pediatric or neonate Changing kV values also means adapting all topogram and the chosen examination type patients. With these features, an additional other values according to the respective (non-contrast, bone, soft tissue, vascular) dose reduction of up to 60% is possible. patient and examination type. into consideration, proposes the appropriate Additionally, the system identifies bariatric 30
  • 32. kV usage [%] 100 90 Without CARE kV 80 70 60 With CARE kV 50 40 30 20 10 0 Tube voltage [kV] Lower dose in 67% of patients 70 80 100 120 140 with CARE kV Benefit for many patients patients and sets the parameters accordingly An evaluation of CARE kV with more than 30% came with no compromise in image to make full use of the system’s reserves to 12,000 patients in the first months after its quality; CNR could be maintained with optimize CNR, and achieve the best image introduction showed that there was a clear no impact on workflow, as all system quality possible for these patients. shift towards 100 kV and 80 kV scans (see parameters are automatically set. above). Dose could be saved in more than two thirds of these patients, compared to the initial protocols. And the dose reduction itself was significant. For example, regular abdomen scans could be reduced to below 10 mGy using 100 kV, down from 14.1 mGy with the former standard protocol set at 120 kV. This dose reduction of approximately 31
  • 33. Combined Applications to Reduce Exposure (CARE) Radiation exposure 9 Comprehensive dose protection Dose reduction lies at the [mSv] Dose reduction in cardiac CT Following the ALARA principle, Siemens heart of the CARE philosophy. 8 introduced its CARE philosophy in the Each application is designed to 7 mid-1990s. The idea is to utilize every contribute dose reduction during 6 means available to reduce patient exposure. every step of the examination process resulting in an absolute Siemens is the only vendor to offer a 5 minimum exposure. dose protection portfolio that comprehen- 4 sively takes all relevant scan parameters 3 into consideration and optimizes the scan accordingly, from patient size to 2 examination type, from mA to kV, and 1 from scan preparation to data evaluation. 0 Adaptive CARE kV CARE MinDose Adaptive SAFIRE ECG Pulsing Dose4D Dose Shield 32
  • 34. collimation: 128 x 0.5 mm spatial resolution: 0.30 mm temp resolution: 142 msec scan time: 5 sec scan length: 119 mm rotation time: 0.28 sec CTDIvol: 7 mGy DLP: 95 mGy cm eff. dose: 1.33 mSv Cardiac examinations are amongst the most sensitive when it comes to dose, so combining all available applications to reduce exposure is key. 33
  • 37. Specify the Unspecific The TrueSignal Technology of the Stellar Detector brings yet another innovation: HiDynamics. Its unique, full dynamic range provides higher image sensitivity, especially for low-signal and low-energy scans. HiDynamics A larger dynamic range expands Thanks to the full electronic integration of the detector’s sensitivity. As in a the TrueSignal Technology, the Stellar backlit photo with a conven- Detector can now utilize its full dynamic tional camera, the front regions range instead of having to switch bandwidth turn black. But with higher sensi- tivity, details remain visible. 1st scan 140 kV like conventional detectors. This unique feature is called HiDynamics. It increases the detector’s sensitivity at the respective energy level and allows for differentiation of 2nd scan 80 kV even the slightest signal changes, especially when scanning with very low kV levels. 36
  • 38. Comparison of the 80 kV Dual Energy data set (left) with the 140 kV Dual Energy data set (right) shows: almost identical image detail level in 80 kV due to the improvement resulting from HiDynamics. The benefits of the Stellar Detector Dose-optimized Single Source DE The benefits of TrueSignal Technology and When multiple scans of the same region The scan mode consists of two successive HiDynamics are also clear in functional have to be performed, dose protection spiral scans at different energy levels. In imaging applications, such as Dual Energy, becomes even more important in order to order to avoid doubling the dose, both spi- as well as in dynamic examinations. They adhere to the ALARA principle. Therefore, rals are performed at half the dose, so that acquire multiple scans of the same region it is imperative to exploit every possibility there is no dose penalty for the resulting to add functional information, such as to reduce dose. Following this philosophy, Dual Energy image. But, as it uses regular tissue characteristics or perfusion data to Siemens has introduced a Single Source spirals, all dose reduction features can be the morphology. In both cases, the scan Dual Energy scan mode that utilizes all utilized without limitations. The capabilities modes acquire data at low kV. HiDynamics dose-reduction functionalities without of the Stellar Detector regarding low significantly increases the detail level and limitations: e.g., CARE Dose4D for real-time dose / signal imaging represents the sharpness of the images for these data sets. mA modulation, or SAFIRE to reduce the industry’s only Single Source Dual Energy mA created by iterative reconstruction. scan mode optimized for low dose. 37
  • 39. Calculi characterization in clinical routine Urinary stone disease Kidney stones are a good Approximately 13% of men and 7% of require intervention later. Current evidence does not require intravenous contrast and example of how tissue women in the United States will be from the study “Urological Diseases in covers the entire abdomen and pelvis. With characterization can lead diagnosed with urinary stone disease in America” suggests an increasing prevalence this imaging modality, nearly all stone types to finding the appropriate their lives. Most stones are symptomatic of urinary stone disease in the United can be visualized. The essential benefit in therapy. Dual Energy informa- tion adds tissue information and cause pain, obstruction, and infection. States. In addition, the likelihood of recur- the diagnosis with Dual Energy CT is that to the morphology. They frequently require visits to the emer- rence is estimated to be up to 50 % during the stone type can be identified. With this gency room, hospitalization, mechanical a five-year period. Thus, the diagnosis of information at hand, the appropriate extraction or even surgical removal. Some kidney stones has substantial impact with treatment can be applied. For patients, this stones may be asymptomatic and are respect to patient morbidity and healthcare means that many interventional treatments only detected incidentally. However, even budgets. The imaging modality of choice for can be avoided, as it can be determined when stones are initially asymptomatic, urinary stone disease is a low-dose, non- upfront if a stone can be treated with symptoms may develop very quickly and contrast CT scan. It is very easy to perform, drugs or not. 38
  • 40. collimation: 128 x 0.6 mm spatial resolution: 0.33 mm scan time: 1.3 sec scan length: 117 mm rotation time: 0.5 sec CTDIvol: 5.28 + 3.02 mGy (140 / 80 kV) DLP: 80 + 40 mGy cm (140 / 80 kV) eff. dose: 1.8 mSv Characterization with syngo Single Source DE Kidney Stones supports treatment decisions. 39
  • 41. Gout identification in clinical routine Gout Gout is the most widespread Gout is the most widespread form of recurrent episodes. The classic symptoms duced by the disease is directly verified, form of crystal arthropathy and a crystal arthropathy and the most common of gout are painful, visibly swollen confirming the definite diagnosis of gout. common inflammatory joint inflammatory joint disease in men. It is peripheral joints. However, gout is difficult The benefit for patients is not only that disease. However, gout is difficult caused by the deposition of uric acid to diagnose, as there are various forms of the painful puncture in a conventional to diagnose. Dual Energy can detect gout in regions that are crystals in joints. Up to 1 in 200 people in arthritis that have similar symptoms. With examination can be avoided, but also often overlooked. the western world, 2.1 million people in the Dual Energy CT and syngo® Dual Energy that the risk of false negative outcomes US, and some 1.5 million people in Germany Gout, a non-invasive assessment of gout is is reduced in cases where the puncture are currently afflicted by this painful, feasible. The algorithm color codes different misses the respective tissue. destructive disease. Furthermore, due to our attenuation values at different energy levels eating habits, these figures are constantly so that the uric acid crystals are color coded increasing. Gout can affect numerous joints in red, while calcium and bone formations throughout the body, especially during are displayed in blue. Thus, uric acid pro- 40
  • 42. collimation: 128 x 0.6 mm spatial resolution: 0.33 mm scan time: 4 sec scan length: 181 mm rotation time: 0.5 sec CTDIvol: 3.32 + 4.46 mGy (140 / 80 kV) DLP: 71 + 95 mGy cm (140 / 80 kV) eff. dose: 0.13 mSv Clear identification with syngo Single Source DE Gout avoids false negative diagnosis of conventional procedures. 41
  • 43. Reducing metal artifacts in clinical routine Metal artifact reduction with Dual Energy Metal artifacts pose severe A big challenge in CT imaging is the impact artifact free as possible. For example, when And syngo Dual Energy Monoenergetic difficulties in CT imaging of metal objects on image quality. Due to assessing organs in the pelvic region, images Imaging enables the minimization of metal due to the resulting artifacts. the high attenuation of metal compared to are often impaired if the patient has a hip artifacts by specifically selecting the respec- Single Source Dual Energy the surrounding tissue, images can suffer prosthesis. The high attenuation of this mas- tive kV level at which the metal objects have now delivers a solution. from streaks or even shadows around sive metal object causes adjoining regions least impact on image quality. With this the metal objects. The cause for this is to suffer from very low signals. Until now, unique combination, implants, clamps or so-called ‘beam starvation.’ Typical metal these artifacts could not be compensated screws can be ideally dealt with in order to artifacts result from implants, e.g., in teeth, for. But now, two solutions come together: obtain the highest diagnostic outcome. or when clamps and screws are used in The unique Stellar Detector in the invasive treatments. But when it comes to SOMATOM Definition Edge is specifically treatment decisions or treatment follow-up, optimized to handle low signals with its it is essential that the image is as TrueSignal Technology and HiDynamics. 42
  • 44. collimation: 128 x 0.6 mm spatial resolution: 0.33 mm scan time: 5 sec scan length: 228 mm rotation time: 0.5 sec CTDIvol: 12.31 + 4.46 mGy (140 / 80 kV) DLP: 380 + 129 mGy cm (140 / 80 kV) eff. dose: 7.64 mSv Significant reduction of metal artifacts from hip implant with syngo Single Source DE Monoen- ergetic delivers much higher diagnostic image quality 43
  • 45. Improved dynamic imaging in clinical routine Adaptive 4D Spiral and HiDynamics Perfusion information is Stroke is one of the three most frequent With the Adaptive 4D Spiral, Siemens has Spiral are specifically set to this length crucial in many clinical fields causes of death worldwide. The diagnosis introduced a scan mode that performs per- for stroke evaluations. In addition, the such as stroke or tumor and treatment of stroke cases is a clinical fusion evaluations beyond the limitations of SOMATOM Definition Edge, with the Stellar assessments. The Adaptive 4D field in which time is of the essence – or a static detector. By applying a continuously Detector and HiDynamics, is the perfect Spiral is key to making these exams ready for clinical practice. where ‘time is brain,’ meaning that the right repeated bi-directional, smooth table choice for better differentiation of the decisions have to be made ideally within the movement over the desired scan range, perfusion level, as brain perfusion studies first hours after the first symptoms have a perfusion assessment covering a region are typically performed at 80 kV. Regardless occurred. Consequently, it is essential that of up to 15 cm can be performed. Recent of cause – from infarctions due to stroke the diagnostic information is delivered publications have shown that a scan range and extensive bleeding, to subarachnoid quickly, reliably, and accurately, and gives of approximately 10 cm is ideal to assess hemorrhage or a ruptured aneurysm –  a comprehensive overview about the status brain perfusion. Consequently, the neuro seeing clearly makes a crucial difference of the disease. perfusion scan modes with the Adaptive 4D in determining treatment. 44
  • 46. collimation: 128 x 0.6 mm scan time: 45 sec scan length: 100 mm rotation time: 0.285 sec CTDIvol: 260 mGy DLP: 3069 mGy cm eff. dose: 6.4 mSv Comprehensive perfusion evaluation with syngo VPCT Neuro delivers crucial information regarding tissue at risk after a stroke. 45
  • 47. SOMATOM Definition Edge The Reference in Single Source CT See the unseen Edge Technology – The reference in image quality • Unprecedented spatial resolution • Uncompromised temporal resolution • nparalleled acquisition speed U Get more from less TrueSignal Technology – The reference in dose efficiency • Optimized low-signal imaging • ptimized low-dose imaging O • ptimized patient-centric imaging O Specify the unspecific HiDynamics – The reference in functional imaging • Routine ready Single Source Dual Energy • Routine ready metal artifact reduction • Routine ready dynamic imaging 46
  • 48. Technical Specifications • Stellar Detector with TrueSignal Technology • 256 x 0.5 mm slices and 0.30 mm spatial resolution with Edge Technology • Dose-optimized Single Source Dual Energy and HiDynamics • 128-slice acquisition with STRATON tube and z-Sharp Technology • Up to 384-slice reconstruction • 0.28 sec rotation time with 142.5 sec temporal resolution • 1.7 maximum pitch with 230 mm/sec acquisition speed • Patient table: 227 kg capacity (300 kg optional), 200 cm scan range • With up to 60 fps FBP and 20 fps SAFIRE reconstruction speed • 4D scan range: 15 cm for perfusion, 48 cm for CTA imaging with Adaptive 4D Spiral • Reduced energy consumption by up to 20% in system stand-by with the Stellar Detector 47
  • 49.
  • 50. In the event that upgrades require FDA approval, SOMATOM Definition Edge is under development, Siemens cannot predict whether or when the FDA will and is not commercially available in the US. issue its approval. Therefore, if regulatory clearance The information about SAFIRE (Sinogram Affirmed is obtained and is applicable to this package, it will be Iterative Reconstruction) is being provided for planning made available according to the terms of this offer. purposes. The product is pending 510(k) review, and is On account of certain regional limitations of sales not yet commercially available in the US. In clinical rights and service availability, we cannot guarantee practice, the use of SAFIRE may reduce CT patient dose that all products included in this brochure are available depending on the clinical task, patient size, anatomical through the Siemens sales organization worldwide. location, and clinical practice. A consultation with a Availability and packaging may vary by country and is radiologist and a physicist should be made to deter- subject to change without prior notice. Some/all of the mine the appropriate dose to obtain diagnostic image features and products described herein may not be quality for the particular clinical task. available in the United States. The information in this document contains general technical descriptions of specifications and options as well as standard and optional features which do not Courtesy list Global Business Unit always have to be present in individual cases. Department of Radiology, University of Erlangen, Germany Siemens AG Mayo Clinic, Rochester (Minnesota), USA Medical Solutions Siemens reserves the right to modify the design, Nan Xi Shan Hospit al / Guilin, P.R. China Computed Tomography packaging, specifications, and options described herein Beihua University 1st Hospital / Jilin, P.R. China Radiation Oncology without prior notice. Please contact your local Siemens Siemensstr. 1 sales representative for the most current information. DE-91301 Forchheim Note: Any technical data contained in this document Germany may vary within defined tolerances. Original images Order No. A91CT-04015-51C1-7600 | Printed in Germany Phone: +49 9191 18 0 always lose a certain amount of detail when reproduced. CC CT WS 11111.5 | © 11.2011, Siemens AG Fax: +49 9191 18 9998 Global Siemens Headquarters Global Siemens Healthcare ­ eadquarters H Legal Manufacturer Siemens AG Siemens AG Siemens AG Wittelsbacherplatz 2 Healthcare Sector Wittelsbacherplatz 2 80333 Muenchen Henkestrasse 127 DE-80333 Muenchen Germany 91052 Erlangen Germany Germany Phone: +49 9131 84 0 www.siemens.com/healthcare