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Lecture 2. Wound management
products WOUND AND PAIN
           MANAGEMENT
           3971
   1


       RALUCA DUCAR/ 3971NRS/ 2010-2011
LEARNING OBJECTIVES

1.Understand the “TIME” concept in wound
management
2.Discuss debridement as part of treatment plan.
3.Identify signs of infection and discuss interventions
related measures.
4.Discuss the benefits of maintaining moist wound
environment.
5. Describe the properties of the eight main categories
of wound dressing.

                                                      2
6. State indication, precautions and contraindications
of the each of the wound dressings
7. Discuss new advances in wound management
(tissue adhesive, growth factors, biosynthetic dressing
).
8. Compare sterile with clean techniques for wound
care.
9.Identify types of antiseptic agents used for wound
care




                                                      3
EXPECTED OUTCOMES
By the end of the session you will be able to:



  1.Demostrate understanding of wound
  management principles related to “TIME” frame.
  (wound debridement, managing infection,
  keeping moisture wound environment)
  2. Recognize types of antiseptic agents used for
  wound care
  3. Differentiate between the 8 main types of
  dressings

                                                     4
4.Demonstrate willingness to gain more knowledge
    related to advanced methods used in wound care (web
    search)
    5. Apply learned principles of dressing techniques in
    clinical settings

    PREREQUISITES
-   MYERS (2008) chapters 5 ,6,7 (pp.70-155)
-   Potter,P.A.,Perry,A.G.,(2009).Fundamentals of
    Nursing.(7th ed).Mosby pp.1313-1321
-   Lecture handout



                                                        5
WOUND BED PREPARATION -WBP
To achieve an effective outcome, a wound should
   have:
1.   Well-vascularized wound bed
2.   Minimal bacterial burden
3.   Little or no exudate




                                                  6
WBP has 4 aspects


1.   Debridement
2.   Exudate management
3.   Bacterial imbalance resolution
4.   Undermined epidermal margin

                               (Schulth et.al.2003)


                                                      7
FALANGA (2004) HAS UTILIZED THE WORK OF
SCHULTZER ET AL. (2003) TO DEVELOP A FRAMEWORK
CALLED TIME TO PROVIDE A COMPREHENSIVE
APPROACH TO CHRONIC WOUND CARE.


    T    Tissue management ( non-
         viable)

     I   Inflammation & infection control

    M    Moisture Balance


     E   Epithelial Edge advance            8
T-TISSUE MANAGEMENT
       PREDOMINAT TYPE OF NECROSIS

ESCHAR          SLOUGH          FIBRIN        HYPERKERATIN      GANGRE
                                              OSIS              NE
Hard            Soft, soggy     Soft, soggy   Hard              Hard

Soft, soggy     Soft stringy    Soft,         Soft, soggy
                Mucinous        stringy
Black/brown     Yellow/tan      Mucinous      White/gray        Black/brow
                                yellow/whit                     n
Firmly          Firmly          e             Firmly attached
attached        attached                                        Firmly
                                Attached      Surrounds wound   attached
Attached base   Attached base   base          adges
                Loosely         Loosely
                attached        attached
                                                                       9
                clumps          clumps
Tissue management
   Assessment for non viable tissue.
   Wound debridement is the principle intervention




        Is the removal of
        necrotic tissue, foreign
        material and debris
        from the wound bed
                 (Myers, 2008)




                                                     10
T-TISSUE MANAGEMENT
Purposes of debridement
• Decrease bacterial concentration within the
  wound bed and the risk of infection.
• Increase the effectiveness of topical
  antimicrobials.
• Improve the bactericidal activity of leukocytes.

• Shorten the inflammatory phase of wound healing.

• Decrease the energy required by the body for
  wound healing.
• Eliminate the physical barrier to wound healing.

• Decrease wound odor.
                                                11
Debridement options
•   Sharp or surgical
•   Autolytic
•   Enzymatic
•   Mechanical
•   Biosurgery or larval therapy




                                   12
Sharp or surgical:                involves using forceps,
scissors, or a scalpel to selectively remove devitalized
tissue, from a wound bed. Fastest and most aggressive.


Autolytic:       uses the body’s own (endogenous)
enzymes, including collagenase to digest necrotic tissue
and macrophage to phagocytose debris by applying a
moisture retentive dressing and leaving it in place for
several days (Hydrocolloids, hydrogels, & alignates).




                                                            13
Enzymatic or chemical debridement: is
the use of a topical exogenous enzyme
(collagenase, elastase, & fibrinolysin) to
remove devitalized tissue.

Mechanical: involves the use of force to
remove devitalized tissue, foreign matter, and
debris. Nonselective debridement type that
includes:
 - Wet-to-dry dressings
 - High Pressure wound irrigation
 - Whirlpool baths                           14
Biosurgical or larval parasitic
1. Mechanical movement loosen surface
   debris
2. larvae secrete enzymes into the wound
   that break down necrotic tissue to a
   semi-liquid form
3. Larvae ingest the dead tissue, leaving
   only the healthy tissue.



                                        15
GENERAL DEBRIDEMENT INDICATIONS
THE RED-YELLOW-BLACK SYSTEM
COLOR      WOUND BED               TREATMENT GOALS
           DESCRIPTION


RED        Pale, pink,beefy red    Protect wound
           granulation tissue      Maintain worm , moist
                                   environment
                                   Protect periwound



YELLOW     Moist yellow slough     Debride necrotic tissue
           Vary in adherence       Absorb drainage
                                   Protect periwound


BLACK      Thick ,black,adherent   Debride necrotic tissue
           eschar,
                                                        16
GENERAL CONSIDERATIONS FOR
DEBRIDEMENT
  Wound characteristics- etiology, size, presence of
  infection, amount of necrotic tissue
  Patient’s general health, nutrition and other
  medical conditions (immunosuppression,
  thrombocytopenia)




                                                       17
I   INFLAMMATION/ INFECTION




                              18
Specific Treatment Objectives for Infected
 wounds
•   To identify the infective organism.
•   To control and/or eliminate wound infection.
•   To remove devitalized tissue from the wound
    bed.
•   To cleanse the wound surface.
•   To absorb excess exudate production.
•   To protect the surrounding skin from the
    effects of maceration.
•   To control pain/discomfort.


                                                   19
HOW DO WE KNOW THE WOUND IS
INFECTED?
  ASSESSMENT:
- five cardinal signs of infection:R.C.T.D.F
- Decline in wound status

- Detect presence of silent infectinos- abcess

  Presence of biofilms with incresed bacterial
  resistance
  Wound cultures (tissue biopsy and swab
  cultures)


                                                 20
HOW DO WE TREAT AN INFECTED
WOUND?

 1.Topical antimicrobial therapy- in order
 to provide an agent that destroys the offending
 organism
          - topical ointments or creams are applied to
 wound surface, penetrate the wound bed to the site
 of infection and inhibit bacterial growth
          - use of antimicrobial-impregnated wound
 dressings
          - use of silver as broad spectrum
 antimicrobial
                                                     21
Advantage of topical antimicrobial use is :
       -lower cost than systemic therapy and ease
of application
       -it will decrease bacterial load if applied
properly
       -they are applied direct to wound bed – better
to treat wounds with compromised circulation

Disadvantage :- needs frequent application
       -sensitivity and allergic reactions
       - increased chance for microbes to become
resistant


                                                   22
2. ANTISEPTIC AGENTS
(ACETIC ACID,
                                       Antimicrobial solution
CHLORHEXIDINE, HYDROGEN                    that prevents
PEROXIDE, POVIDONE-IODINE)              infection by killing
                                         microorganisms



  Previously were considered to reduce the rate of
    infection and speed wound repair

    Research showed that beside being broad-spectrum
    anti microbial, antiseptic agents are also cytotoxic to
    fibroblast, kerationcytes and neutrophyls

    ----------increse the duration of inflammatory response
    and delay epithelialization and wound contraction 23
Used to decrease bacterial growth on inanimate objects
Reduce bacterial concentrations on intact skin- used as
surgical scrub
Can be used for short period of time on open wounds
               e.g. patients with bite from animals in
the farm can have short term use of povidone-iodine
because this wounds are multimicrobial

                        (Myers, 2008;p.104-113)



                                                     24
3.SYSTEMIC ANTIMICROBIAL
THERAPY
 Prescribed for patients with sepsis or deep space
 infections , alone or in combination with topical
 antibiotics
 Advantage –reduce bacterial load, better patient
 compliance with treatment
 Disadvantage- more frequent and severe adverse
 reactions, development of resistant stains




                                                     25
REVIEW:
 T- TISSUE MANAGEMENT
      DEBRIDMENT Sharp or surgical
                    Autolytic
                    Enzymatic
                    Mechanical
                    Biosurgery or larval therapy
 I- INFECTION/ INFLAMMATION




                                               26
M
    M MOIST WOUND HEALING
Traditional theory says: “wounds should be kept dry and
clean so that scab can form over the wound” Sussman,Bates-
Jensen(2008)


Practice shows that scab is a barrier to healing- because it
interferes with moving of epithelial cells- poor cosmetic
results and scarring
The wounds should be managed in a moist environment so
epithelial cells will be able to move

Moist wound heals 3-5 times faster than dry wound because
moist facilitates the three phases of wound healing process
.Myers (2008)                                           27
The amount of moisture is not known exactly-
-a wound too dry will result in crust formation and will
  lack the enzymes and growth factors that facilitate
  healing
-a wound that is to wet can delay healing because of the
  extra fluid around the wound which will produce
  maceration of tissue




                                                       28
DRESSINGS -FUNCTION
Create a moist wound environment
      - if wound too wet-dressing will absorb the excess
exudate
      - if wound too dry- dressing will donate moisture
to it
Provide thermal insulation maintain temp.37-
38degrees C
       -this temp. increases oxygen saturation and
decreases hemoglobin’s affinity for oxygen.


                                                      29
-wound dressing should protect against infection
- wound dressing should protect exposed nerve
endings, decreasing the pain
-provide hemostasis, edema control elimination of dead
           -dead space=void left by a wound cavity,
undermining or tunneling---it must be avoided to
prevent abscess formation and premature wound
closure
Provide gas exchange between wound and
environment




                                                    30
TYPES OF WOUND DRESSING

  PRIMARY DRESSING
-Comes in direct contact with wound
            e.g.Band Eid
  SECONDARY DRESSING
-Placed over primary dressing to improve
  protection
            e.g. Self-adhesive bandage
  placed over primary dressing
                                           31
CLINICAL DECISION MAKING
    MOST APPROPRIATE WOUND CARE

-




                                  32
MOISTURE RETENTIVE DRESSING
Maintain an ideal wound healing enviromnent
Are specialized synthetic or organic dressings that are
more occlusive than gauze



Describes the ability of a dressing to transmit
moisture ,vapor and gases from wound to
atmosphere


Have a lower moisture vapor transmission rate than
gauze
Allows patients to bathe, swim without contaminating
the wound                                          33
Maintain wound temperature better than gauze
Protect the wound from trauma and infection
Are adhesive---there is no need for secondary
dressing
Are elastic and stay in place for 3-7 days
Stimulate granulation tissue formation, collagen
synthesis and epithelialization

Main risk for using moisture retentive dressing
             INFECTION
        TRAUMA TO THE WOUND BED
     MACERATION OF SURROUNDING SKIN

                                                   34
8 TYPES OF DRESSING
1.GAUZE DRESSING
2.IMPREGNATED GAUZE
3.SEMIPERMEABLE FILMS
4.SHEET HYDROGELS
5.SEMIPERMEABLE FOAMS
6.HYDROCOLLOIDS
7.ALGINATES
8.COMPOSITE DRESSINGS




                        35
1.
.            GAUZE DRESINGS


  WOVEN GAUZE-
-made of cotton yarn or thread
  NONWOVEN GAUZE –
-made of synthetic fibers pressed together (have grater
  absorbency)

    Loose weave gauze- aids in medical debridement but
    should not be placed over granulating tissue
    Gauze is highly permeable and nonocclusive and can
    be used as primary or secondary wound dressing     36
MULTILAYER GAUZE DRESSINGS
-   Outer nonocclusive layer ----allows gas exchange
-   Middle antisher layer ---------moves with the patient
-   Nonadherent contact layer—allows absorbtion of exudates,
    reduces moisture less risk for maceration



  ANTIMICROBIAL-IMPREGNATED GAUZE
- The use of such products should be limited ----reduce the
  potential of developing resistant microorganisms
                                                          37
COMMON USES
Both infected and noninfected wounds
Large wounds or irregularly shaped
Packing strips to prevent premature closure or keep
away exudates in tunneling or underminig wounds

CAN BE USED ALONE OR IN COMBINATION
WITH ANTIBIOTICS, ENZYMES, GROWTH
FACTORS, ALGINATES,SEMIPERMEABLE FOAMS
OR FILMS

                                                      38
PRECAUTINONS /CONTRAINDICATIONS

 1.woven gauze require more force to remove----
 potential wound trauma
 2.woven gauze may leave residue to which body will
 respond by forming granuloma
  rolled gauze should be applied snuggly but without
 tension---to prevent a tourniquet like effect
 Telfa dressing---nonadherent, little absorption , keeps
 wound exudates close to wound---maceration of tissue


                                                       39
2
IMPREGNATED GAUZE DRESSING

    Mesh gauze non adherent, moderate occlusive,
    Impregnated with petrolatum, bismuth, zinc
    Petrolatum impregnated gauze might facilitate wound
    healing by decreasing trauma during dressing
    Can be used as contact layer on granulating wound
    beds, combined with secondary gauze dressing
    Used to burn wounds because have pain free removal


                                                     40
PRECAUTIONS/CONTRAINDICATION
S

 Bismuth (from xeroform dressings) is cytotoxic to
 inflammatory cells-----cause increased
 inflammatory response (not advisable for pt with
 venous insufficiency ulcer)
 Iodine-impregnated gauze cytotoxic to human
 cells only mild antimicrobial




                                                     41
3.
  SEMI PERMEABLE FILMS
Thin flexible transparent sheets with adhesive backing
Permeable to water vapor, O2, CO2 but impermeable
to bacteria and water
Have little absorptive capabilities , but are comfortable
because of elasticity
Should be applied without tension and wrinkles and
can stay in place for 5-7 days
Should NOT be used in cavity wounds or when heavy
drainage is noted


                                                       42
•COMMONLY USED FOR SUPERFICIAL
WOUNDS (TEARS, LACERATIONS,
ABRASIONS), INTRAVENOUS CATHETER
SITES, AREAS OF FRICTION
   to prevent maceration ---apply on areas of intact skin
-skin should not be oily or wet
-if a channel or wrinkle forms----change dressing
-NOT to be used on infected wounds




                                                            43
4.
 SHEET HYDROGELS
80-90% water or glycerin based wound dressing
Absorb minimum amount of fluid by swelling
Donate moisture to dry wounds
Decrease pain by cooling the wound bed
Are permeable to gas and water---less effective
bacterial barrier




                                                  44
PRECAUTIONS/CONTRAINDICATIONS
   Are not able to absorb heavy drainage
   Are absorbing very slowly----should not be used on
   bleeding wounds
   Require secondary dressing

 : USE             minimal or moderate draining wound
         -can be used within casts or splints to decrease
   pressure
 - Effective at softening eschar to facilitate autolytic
   debridment
                                                            45
5.
      SEMIPERMEABLE FOAMS
Made of polyurethaine, permeable to gas but not
to bacteria
have high moisture vapor transmission
Provide thermal insulation
Effective in treatment of stage II and III pressure
ulcer




                                                      46
- WOUNDS WITH MINIMAL AND HEAVY
USES EXUDATES
        -GRANULATING OR SLOUGH COVERED
        PARTIAL AND FULL THICKNESS WOUND
        -SEMIPERMEABLE FOAMS –USED IN DONOR
        SITES , OSTOMY SITES, MINOR BURNS,
        DIABETIC ULCER
  PRECAUTIONS
-Not recommended in dry or eschar-covered wounds
-not indicated for arterial ulcers---because of enhancing
  dryness
- Not indicated for area of high friction—heel ulcers



                                                        47
6.HYDROCOLLOIDS

Contain hydrophilic colloid particles like gelatin,
pectin,
Have various absorption abilities
Absolves exudates by swelling into a gel-like
mass
Provide thermal insulation to wound bed
Impermeable to water, oxygen ,bacteria




                                                      48
Uses- indicated for partial and full-thickness wounds
       -can be used on granular and necrotic wounds
       -used on minor burns, and pressure ulcers




          Duo Derm- effective
         barrier against urine,
             stool, MRSA,
            hepaB,HIV and
            Pseudomonas
               Arginosa


                                                        49
7.        ALGINATES
  Contain salts of alginic acid from sea weeds and
  covered in calcium/sodium salts
  When placed on wound, it reacts with the serum and
  forms a hydrophilic gel
  Are highly permeable and non occlusive----require
  secondary dressing
  Stimulate macrophage activity
  Uses: highly draining wounds
-partial and full-thickness wound
-granular and eschar-covered wounds
                                                       50
PRECAUTIONS/CONTRAINDICATIONS

Not recommended for use on full thickness burns
Not to be used on wounds with exposed tendon, joint
capsule, bone
Use with moisture barer to protect periwound skin
from maceration




                                                      51
8.
        COMPOSITE DRESSING
 Multilayer dressing that can be used as primary
 or secondary wound dressings

 3 layers
              1. -inner contact-non adherent,
 prevents trauma to wound bed when dressing
 changes
 2.-middle layer-absorbs moisture and keeps it
 away from wound bed to prevent maceration
 3.-outer layer-bacterial barrier

                                                   52
SILVER DRESSING
-silver is antiseptic
-dressings may be primary or secondary, adhesive or
  non-adhesive
-release of silver ions----blue-black wound discoloration
No evidence that silver is effective in presence of slough
  or eschar
Silver is cytotoxic to fibroblast




                                                         53
CHARCOAL DRESSING
 Key function of dressings is to control wound odor by
 absorbing odor producing gases released by bacteria----
 --improve the quality of life for patients by allowing
 them to share with normal social activities




                                                      54
SUMMARY
MANAGING EXUDATES WITH
DRESSING

Type of wound          Optimal dressing

0=dry                  Hydrogels, hydrocolloids,
                       interactive wet dressings

1=minimum exudates     Hydrogels, hydrocolloids,
                       semipermeable films, calcium
                       alginates

2= moderate exudates   Calcium alginate, hydrofibre,
                       hydrocolloid paste/powder, foams

3=heavy exudates       Hydrofibre dressings, foam
                       sheets/cavity, wound/ostomy bags
                                                          55
WHEN CHOOSING TYPE OF
DRESSING USED WE HAVE TO
CONSIDER ALSO THE
SURROUNDING SKIN

             EDGE ,EPITELIAL ADVANCEMENT
     E

Signs of epithelial (edge) advancement

1.   WB filled with granulating tissue.
2.   Epithelialization at the wound margins.



                                               56
THE FOLLOWING QUESTIONS
SHOULD BE ANSWERED PRIOR TO
THE CLEANSING OF ANY WOUND:


1. What is the purpose of wound
   cleansing?
2. What method of wound cleansing would
   be most appropriate?
3. Does the wound require cleaning at
   each dressing change?
4. What type of wound cleansing product
   would be most appropriate?         57
1.THE PURPOSE OF WOUND CLEANSING:

 •   Wound infection.
 •   Excessive exudate.
 •   Presence of foreign bodies, debris,
     eschar or slough.
 •   A need to reduce contamination or
     devitalised tissue prior to suturing,
     in wounds healing by delayed
     primary intention (i.e. tertiary
     intention).                             58
DECIDING TO CLEANSE A WOUND
SHOULD BE BASED ON THE
FOLLOWING:

• The size, shape and location of the
  patient’s wound.
• The condition of the wound and
  stage of healing.
• The availability and effectiveness of
  different methods of cleansing.
• The availability and effectiveness of
  different cleansing agents.
• The patient’s perceptions and needs

                                          59
CLEANSING TECHNIQUE

•   Clean versus sterile technique
•   Use of Normal saline and tap water
•   Hand washing is essential to reduce infection
•   Wound field concept
•   Dirty hand & clean hand




                                                    60
IRRIGATION VS.
SWABBING

Swabbing the wound surface of a wound
may      mechanically   dislodge  loose,
devitalised tissue but does not actively
remove pathogens from the wound.

Irrigation under pressure is an effective
method of cleansing wounds that are
infected or heavily contaminated. High
pressure irrigation using a 30ml syringe
and an 18-20G needle lowers the infection
rates in contaminated wounds.               61
STERILE VS.CLEAN TECHNIQUE
   Sterile technique -is defined as use of sterile
   equipment, ( gloves,wound dressing, instruments) in
   order to reduce exposure to microorganisms.
-----------only sterile items may contact the pt’s wound,
------------use of sterile gloves and sterile field
------------meticulous set-up and maintenance of sterile
   field
  ( review table.6-8,p.117 text book)



                                                            62
Clean technique- procedures that reduce overall
   number of microorganisms
-------------------hand, washing, sterile instruments
-------------------use of clean gloves and maintenance of
   clean field
-------------------use clean hand dirty hand dressing
   procedure

                                     (see table 6-
  10,p.117,text book)



                                                            63
CONCLUSION OF RESEARCH
- No difference in the rate of wound
  healing was found when comparing
  sterile with clean technique dressing
-clean technique less expensive---
-clean technique----standard in wound
  management
-sterile technique---reserved for wounds
  that require packing, severe burns,
  wounds of immunosupressed patients
                                           64
CLEANING AGENTS
 Antiseptics
 Antibiotics
 Honey
 Saline 0.9%
 Tap water



                  65
ANTISEPTICS
•   Defined as a non-toxic disinfectant, which can be
    applied to skin or living tissues & has the ability to
    destroy vegetative compounds, such as bacteria, by
    preventing their growth.
•   If antiseptics are simply used to wipe across the wound
    surface, they will have little effect.
•   They need to be in contact with bacteria for about 20
    min. before they actually destroy them.
•   They can applied in the form of soaks or incorporated
    into dressings, ointments, or creams.

                                                         66
LOTIONS - ANTISEPTICS
1.   Cetrimide
2.   Chlorhexidine
3.   Hydrogen Peroxide
4.   Iodine
5.   Potassium Permanganate
6.   Proflavine
7.   Silver
8.   Sodium Hypochlorite
LOTIONS - ANTISEPTICS
1. Cetrimide
•   Useful for its detergent properties, particularly for
    the initial cleansing of traumatic wounds or the
    removal of scabs & crusts in skin disease.
•   It is mostly only used in ER for initial cleansing of
    wounds rather than a routine cleanser
•   Two dangers should be noted:
    - Skin irritation & sensitivity
    - Very easy to become contaminated by bacteria, especially Pseudomonas
    aeruginosa.



                                      (Dealey, 2005)
LOTIONS - ANTISEPTICS
•   It is available as a cream or as a lotion in combination
    with chlorhexidine.




                                                          69


                           (Dealey, 2005)
LOTIONS - ANTISEPTICS
2. Chlorhexidine
It is effective against G-ve & G+ve.
It could maintain its antimicrobial levels for a
  period of time when impregnated into a dressing.
However, its efficacy is rapidly diminished in the
  presence of organic material such as pus or blood.




                                                       70


                         (Dealey, 2005)
LOTIONS - ANTISEPTICS


It     is more suitable for
     disinfection & hospital
     hygiene     rather than
     wound care




                                          71


                         (Dealey, 2005)
LOTIONS - ANTISEPTICS
3. Hydrogen Peroxide 3%
• Effective against anaerobes

• It loses its effect when comes in contact with
  organic material such as pus or cotton gauze.
• Cytotoxic to fibroblast unless diluted to a
  strength of 0.003%. This dilution is not effective
  against bacteria. But, this dilution still inhibits
  keratinocyte migration & proliferation.




                         (Dealey, 2005)
LOTIONS - ANTISEPTICS
It is no longer widely used as there is
  no evidence to demonstrate its
  efficacy & there are number of
  other more alternatives.




                         (Dealey, 2005)
LOTIONS - ANTISEPTICS
4. Iodine
• Broad-spectrum antiseptic

• Used in wound care as povidine iodine 10% which
  contains 1% iodine.
• Used as a skin disinfectant & to clean grossly
  infected wounds.
• Effective against MRSA.




                       (Dealey, 2005)
LOTIONS - ANTISEPTICS
Debate…?
Lineaweaver et al. (1985) found that it is Cytotoxic
  to fibroblasts unless diluted to 0.001%, retards
  epithelialization & ↓ the tensile strength of the
  wound.

However,

Bennet et al. (2001) found that it significantly ↑
 fibroblast proliferation slightly ↑ neodermal
 regeneration & epithelialization.



                         (Dealey, 2005)
LOTIONS - ANTISEPTICS
•   In 2003, Selvaggi et al., have reviewed &
    appraised the role of iodine & concluded that
    povidine iodine is an effective antibacterial that
    is superior to other products & has no problems
    with resistance.

    Iodine should not be used for the patients with
    thyroid disease or those who are sensitive to the
    product.


                                                         76


                           (Dealey, 2005)
LOTIONS - ANTISEPTICS
Povidine iodine is available in ointment, spray, &
 powder form & impregnated into dressings.




                                    Betadine

                                                     77


                        (Dealey, 2005)
LOTIONS - ANTISEPTICS
5. Potassium Permanganate 0.01%
•   Used on heavily exuding
    wounds.
•   Generally, associated with leg
    ulceration.
•   Found in the form of tablets; to
    be dissolved in 4 L of water.




                          (Dealey, 2005)
LOTIONS - ANTISEPTICS
6. Proflavine
• Has a mild bacteriostatic effect on G+ve, but no
  effect on G-ve.
• It is available as a lotion




                                                     79


                         (Dealey, 2005)
LOTIONS - ANTISEPTICS
7. Silver
• Has a bactericidal effect on a wide range of
  bacteria (Dealey, 2005)
Problem
• It is extremely caustic, stains the skin black.
• Prolonged use causes ↓Na, ↓K, & ↓Ca (Dealey,
 2005)
Solution
• To overcome these problems → a cream,
  silver sulphadiazine, was developed →
  successful in controlling burn wound
  infections (Lansdown, 2004)
LOTIONS - ANTISEPTICS
Available in 3 modalities:
•   Liquid (Silver Nitrate)
•   Cream (Silver Sulphadiazine)
•   Silver-coated dressing




                         (Dealey, 2005)
LOTIONS - ANTISEPTICS
8. Sodium Hypochlorite
Originally used in the 1st World
  War.
Have few beneficial effects & do
  much harm.




                        (Dealey, 2005)
LOTIONS - ANTIBIOTICS
•   D’Arcy (1972) recommends that any antibiotic that
    is used systematically should not be applied to the
    skin.
     However, antibiotics that are not appropriate for
    systemic use may be developed for use on the skin
    or in wound care.
•   → creams, gels, ointments or impregnated
    dressings containing gentamicin, tetracycline,
    fusidic acid, or chlortetracycline. Should not be
    used as these antibiotics are used systematically
    (Dealey, 2005).
•   Mupirocin could be used for treatment of
    MRSA

                         (Dealey, 2005)
LOTIONS - ANTIBIOTICS
•   A range of antibiotics is available in topical form.
•   There is considerable risk of sensitization to the
    patient as well as the development of resistance
    organisms.
•   Systematic antibiotics are the treatment of choice
    when treating infected wounds.




                            (Dealey, 2005)
LOTIONS - HONEY
Honey has been used in wound care since ancient
 times.
Mole (1999) discussed the role of honey & its
 properties:
 Antibacterial action
 Deodirising action
 Debriding action
 Anti-inflammatory action
 Stimulation of wound healing
 Pain relief (Dunford & Hanano, 2004)
LOTIONS – TAP WATER
•   Is being used more frequently on wound
    areas already colonized such as wounds
    following rectal surgery of foot ulcer.
•   Using tap water to clean wounds did not differ from
    using sterile normal saline in respect of wound
    infection and healing rates.


                             (Fernandez, Griffiths, & Ussia, 2002)


                                                              86
LOTIONS – SALINE 0.9%
•   The only completely safe
    cleansing agent & is the
    treatment of choice for use of
    most wounds.
•   It is used in conjunction with
    many      of    the    modern
    products.
•   It is presented in sachets,
    small plastic containers, &
    aerosols.

                        (Dealey, 2005)
REVISION OF DRESSING TYPES
1. Inert non-stick dressings
  Gauze
  Paraffin    tulle     dressings     (Jelonet®,
  Bactigras®)
  Non-paraffin, non-tulle, woven products, (e.g.
  Adaptic®, Inadine®)
  Non-stick dressings (e.g. Melolin®, Cutilin®)
  Combine

Primary dressing:
• Protective low absorption dressing
                 (Carville, 2005; Dealey, 2005)
DRESSING TYPES REVIEW
Application:
• Clean wound base
• Place shiny side of dressing to wound.
• May require soaking if exudate strikethrough
  has occurred.

Contraindications/Possible Side effects:
• Harsh debridement of the wound bed if
  exudate dries
• Limited use as a primary dressing
• Dries out the wound bed


                (Carville, 2005; Dealey, 2005)
DRESSING TYPES REVIEW
2. Film dressing
  Opsite Flexigrid®
  Opsite Post-Op®
  Tegaderm®
  Polyskin®

Primary and secondary dressing:
• Low exudating wounds, protective dressing.




                 (Carville, 2005; Dealey, 2005)
Application:
• Clean wound base
• Prepare peri-wound area with a protective barrier wipe.
• Apply adhesive side to wound and remove outer layer.
• Adhesive strongest in first 24 hours; can remain for 7 days.
• Observe for maceration, remove if this occurs.


Contraindications/ Possible Side effects:
• Do not apply to infected wounds or if allergic to tapes.
• NB: Green sided Opsite is for wounds, orange sided Opsite is
  for vascular access devices.




                                                                 91

                     (Carville, 2005; Dealey, 2005)
DRESSING TYPES REVIEW

3. Foam dressings
  Allevyn®
  Allevyn Adhesive®
  Allevyn Cavity®
  Cavi-Care®

Primary and secondary dressing:
• Light/mod/highly exudating wounds, protective dressing,
  cavity wounds.



                                                     92

                 (Carville, 2005; Dealey, 2005)
Application:
• Clean wound base
• Read packaged for insertion side (patterned or shiny side up)
• Sheet foam left insitu up to 7 days (24 hours if infected)
• Cavity foams left insitu up to 14 days (daily washing of foam if
  infected)

Contraindications/ Possible Side effects:
• Avoid covering with occlusive dressings.
• Avoid wounds dressed with antibacterial solutions.




                                                                93

                     (Carville, 2005; Dealey, 2005)
DRESSING TYPES REVIEW
4. Hydrogel dressings
  Solugel®
  Intra site® Gel
  Solosite® Gel
  Clear-Site®
  Duoderm® Gel
  Aquaflo®

Primary dressing:
• Slough or necrotic wounds requiring chemical
  debridement.
• Light/moderate exudating wounds, hydrate dry wounds.
                                                         94

                    (Carville, 2005; Dealey, 2005)
5. Hydrocolloid dressings
  Duoderm Extra Thin®
  Duoderm CGF®
  Duoderm® Paste
  Comfeel Plus Transparent®
  Comfeel Plus® Contour Dressing
  Comfeel Plus® Pressure Relieving Dressing
  Comfeel® Paste
  Comfeel® Powder

Primary and secondary dressing:
• Slough wounds requiring autolytic debridement,
  low/moderate exudating wounds.
                                                    95

                   (Carville, 2005; Dealey, 2005)
Application:
• Clean wound base, wipe peri-wound with barrier wipe.
• Warm product in hands to activate adhesive.
• Place adhesive side to wound.
• Leave at least 2 cm border around wound.
• Can be left insitu up to 7 days, dependant on exudate
  level.
• Dressing becomes opaque when due for change.


Contraindications/ Possible Side effects:
• Do not apply to infected wounds or if client is allergic.
• Remove if patient complains of discomfort.
                                                              96

                      (Carville, 2005; Dealey, 2005)
WOUND DRESSINGS REVIEW
6. Alginate dressings
  Kaltostat®
  Algoderm®
  Sorbsan®
  Curasorb®
  Kaltocarb®

Primary dressing:
• Heavily   exudating,      bleeding,        slough   or
  infected wounds.
                                                           97

                (Carville, 2005; Dealey, 2005)
Application:
• Clean wound base
• Lightly pack or line the wound, product swells with
  exudate.
• Avoid pre-moistening the product.
• Discontinue use if the dressing remains dry.
• Can be left insitu up to 4 days, dependant on exudate
  level.
• Requires a secondary dressing.


Contraindications/ Possible Side effects:
• Do not use on dry wounds as it dehydrates the wound
  bed.                                                    98

                    (Carville, 2005; Dealey, 2005)
WOUND DRESSING REVIEW

7. Hydrofiber dressings
  Aquacel

Primary dressing:
• Heavily exudating or infected wounds.




                                                  99

                 (Carville, 2005; Dealey, 2005)
Application:
• Clean wound base.
• Line the wound base with product.
• Cover with a secondary dressing.
• Can be left insitu up to 7 days, dependant on
  exudate level.

Contraindications/ Possible Side effects:
• Heavily infected wounds require Hydrofiber
  impregnated with Silver.
• Do not use in people allergic to hydrocolloids.
                                                    100

                 (Carville, 2005; Dealey, 2005)
WOUND DRESSING REVIEW
8. Non-crystalline Silver dressings
  Acticoat®
  Aquacel Ag®
  Actisorb plus® (charcoal)

Primary dressing:
• Infected wounds (150 pathogens including MRSA
  and VRE), burns, donor and recipient sites.



                                                  101

                (Carville, 2005; Dealey, 2005)
Application:
• Clean wound base.
• Moisten product with sterile water, daily if not enough
  exudate.
• Cut to wound size and shape, apply blue side down.
• Cover with a secondary dressing.
• Can be left insitu up to 7 days, dependant on exudate
  level.

Contraindications/ Possible Side effects:
• Do not use on people going for a Magnetic Resonance
  Imaging.
• Do not use in people allergic to silver.                  102

                     (Carville, 2005; Dealey, 2005)
WOUND DRESSING REVIEW
9. Zinc dressings
  Steripaste®
  Viscopaste®
  Flexidress®
  Gelocast®

Primary dressing:
• Slough wounds, epithelializing wounds and
  to protect limbs at risk of skin tears or
  degloving.                                    103

               (Carville, 2005; Dealey, 2005)
Application:
• Cut length as required, usually 3-4 times the size
  of the wound .
• Fold to make a patch and place over wound.
• Requires a secondary dressing.
• Can be left insitu up to 7 days.


Contraindications/Possible Side effects:
• Allergy to zinc



                                                       104

                  (Carville, 2005; Dealey, 2005)
WOUND MANAGEMENT PRODUCTS
10. Other dressings
  Cadexomer Iodine
  Vacuum assisted closure (VAC)




                                                  105

                 (Carville, 2005; Dealey, 2005)
REFERENCES
Schultz, G.S., Sibbald, R.G., Falanga, V., Ayello, E.A.,
  Dowsett, C., Harding, K., Romanelli, M., Stacey, M.C.,
  Teot, L., Vanscheidt, W. (2003) Wound bed preparation: a
  systematic approach to wound management. Wound Repair
  and Regeneration, 11(2), S1-S28.


Watret, L. (2005). Teaching wound management: a
 collaborative model for future education. Retrieved 6
 September     2009,   from    World    Wound     Wide:
 http://www.worldwidewounds.com/2005/november/Watret/T
 eaching-Wound-Mgt-Collaborative-Model.html


                                                             106
REFERENCES
Falanga, V. (2000). Classification for wound bed preparation
  and stimulation of chronic wounds. Wound Repair and
  Regeneration, 8(5), 347-352.

Falanga, V. (2004). Wound bed preparation: science applied to
  practice, in European Wound Management Association
  (EWMA) Position Document, Wound Bed Preparation in
  Practice, London: MEP Ltd.


Lansdown, A.B.G. (2004). A review of the use of silver in
  wound care: facts and fallacies. British Journal of Nursing,
  13(6), S6-S19.

Lineaweaver, W., Howard, R., Soucy, D., McMorris, S.,            107
  Freeman, J., Crain, C., Robertson, J., & Rumley, T. (1985).
  Topical antimicrobial toxicity. Archives of Surgery, 120,
  267-270.
REFERENECE
Myers,A.B, (2008).Wound management. Principles and practice.(2nd
 ed.)Pearson Education Australia PTY.( pp.71-155)

Bennett, L.L., Rosenblum, R.S., Perlov, C., Davidson, J.M.,
  Barton, R.M., & Nannet, L.B. (2001). An in vivo comparison
  of topical agents in wound repair. Plastic and reconstructure
  surgery, 108(3), 674-685.

Carville, K, (2005). Wound Care Manual (5th ed.). Osborne Park,
  Australia: Silver Chain.

D’Arcy, P.F. (1972). Drugs on the skin: a clinical and
  pharmaceutical problem. Pharmaceutical Journal, 209, 491-492.


Dealey, C. (2005). The Care of Wounds: A Guide for Nurse (3rd ed.).
  Oxford, UK: Blackwell Publishing.
                                                                 108
Fernandez, R., Griffiths, R., Ussia, C. (2002). Water for wound
  cleansing. Cochrane Database Systematic Review, 4.

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Wound care lectures

  • 1. Lecture 2. Wound management products WOUND AND PAIN MANAGEMENT 3971 1 RALUCA DUCAR/ 3971NRS/ 2010-2011
  • 2. LEARNING OBJECTIVES 1.Understand the “TIME” concept in wound management 2.Discuss debridement as part of treatment plan. 3.Identify signs of infection and discuss interventions related measures. 4.Discuss the benefits of maintaining moist wound environment. 5. Describe the properties of the eight main categories of wound dressing. 2
  • 3. 6. State indication, precautions and contraindications of the each of the wound dressings 7. Discuss new advances in wound management (tissue adhesive, growth factors, biosynthetic dressing ). 8. Compare sterile with clean techniques for wound care. 9.Identify types of antiseptic agents used for wound care 3
  • 4. EXPECTED OUTCOMES By the end of the session you will be able to: 1.Demostrate understanding of wound management principles related to “TIME” frame. (wound debridement, managing infection, keeping moisture wound environment) 2. Recognize types of antiseptic agents used for wound care 3. Differentiate between the 8 main types of dressings 4
  • 5. 4.Demonstrate willingness to gain more knowledge related to advanced methods used in wound care (web search) 5. Apply learned principles of dressing techniques in clinical settings PREREQUISITES - MYERS (2008) chapters 5 ,6,7 (pp.70-155) - Potter,P.A.,Perry,A.G.,(2009).Fundamentals of Nursing.(7th ed).Mosby pp.1313-1321 - Lecture handout 5
  • 6. WOUND BED PREPARATION -WBP To achieve an effective outcome, a wound should have: 1. Well-vascularized wound bed 2. Minimal bacterial burden 3. Little or no exudate 6
  • 7. WBP has 4 aspects 1. Debridement 2. Exudate management 3. Bacterial imbalance resolution 4. Undermined epidermal margin (Schulth et.al.2003) 7
  • 8. FALANGA (2004) HAS UTILIZED THE WORK OF SCHULTZER ET AL. (2003) TO DEVELOP A FRAMEWORK CALLED TIME TO PROVIDE A COMPREHENSIVE APPROACH TO CHRONIC WOUND CARE. T Tissue management ( non- viable) I Inflammation & infection control M Moisture Balance E Epithelial Edge advance 8
  • 9. T-TISSUE MANAGEMENT PREDOMINAT TYPE OF NECROSIS ESCHAR SLOUGH FIBRIN HYPERKERATIN GANGRE OSIS NE Hard Soft, soggy Soft, soggy Hard Hard Soft, soggy Soft stringy Soft, Soft, soggy Mucinous stringy Black/brown Yellow/tan Mucinous White/gray Black/brow yellow/whit n Firmly Firmly e Firmly attached attached attached Firmly Attached Surrounds wound attached Attached base Attached base base adges Loosely Loosely attached attached 9 clumps clumps
  • 10. Tissue management Assessment for non viable tissue. Wound debridement is the principle intervention Is the removal of necrotic tissue, foreign material and debris from the wound bed (Myers, 2008) 10
  • 11. T-TISSUE MANAGEMENT Purposes of debridement • Decrease bacterial concentration within the wound bed and the risk of infection. • Increase the effectiveness of topical antimicrobials. • Improve the bactericidal activity of leukocytes. • Shorten the inflammatory phase of wound healing. • Decrease the energy required by the body for wound healing. • Eliminate the physical barrier to wound healing. • Decrease wound odor. 11
  • 12. Debridement options • Sharp or surgical • Autolytic • Enzymatic • Mechanical • Biosurgery or larval therapy 12
  • 13. Sharp or surgical: involves using forceps, scissors, or a scalpel to selectively remove devitalized tissue, from a wound bed. Fastest and most aggressive. Autolytic: uses the body’s own (endogenous) enzymes, including collagenase to digest necrotic tissue and macrophage to phagocytose debris by applying a moisture retentive dressing and leaving it in place for several days (Hydrocolloids, hydrogels, & alignates). 13
  • 14. Enzymatic or chemical debridement: is the use of a topical exogenous enzyme (collagenase, elastase, & fibrinolysin) to remove devitalized tissue. Mechanical: involves the use of force to remove devitalized tissue, foreign matter, and debris. Nonselective debridement type that includes: - Wet-to-dry dressings - High Pressure wound irrigation - Whirlpool baths 14
  • 15. Biosurgical or larval parasitic 1. Mechanical movement loosen surface debris 2. larvae secrete enzymes into the wound that break down necrotic tissue to a semi-liquid form 3. Larvae ingest the dead tissue, leaving only the healthy tissue. 15
  • 16. GENERAL DEBRIDEMENT INDICATIONS THE RED-YELLOW-BLACK SYSTEM COLOR WOUND BED TREATMENT GOALS DESCRIPTION RED Pale, pink,beefy red Protect wound granulation tissue Maintain worm , moist environment Protect periwound YELLOW Moist yellow slough Debride necrotic tissue Vary in adherence Absorb drainage Protect periwound BLACK Thick ,black,adherent Debride necrotic tissue eschar, 16
  • 17. GENERAL CONSIDERATIONS FOR DEBRIDEMENT Wound characteristics- etiology, size, presence of infection, amount of necrotic tissue Patient’s general health, nutrition and other medical conditions (immunosuppression, thrombocytopenia) 17
  • 18. I INFLAMMATION/ INFECTION 18
  • 19. Specific Treatment Objectives for Infected wounds • To identify the infective organism. • To control and/or eliminate wound infection. • To remove devitalized tissue from the wound bed. • To cleanse the wound surface. • To absorb excess exudate production. • To protect the surrounding skin from the effects of maceration. • To control pain/discomfort. 19
  • 20. HOW DO WE KNOW THE WOUND IS INFECTED? ASSESSMENT: - five cardinal signs of infection:R.C.T.D.F - Decline in wound status - Detect presence of silent infectinos- abcess Presence of biofilms with incresed bacterial resistance Wound cultures (tissue biopsy and swab cultures) 20
  • 21. HOW DO WE TREAT AN INFECTED WOUND? 1.Topical antimicrobial therapy- in order to provide an agent that destroys the offending organism - topical ointments or creams are applied to wound surface, penetrate the wound bed to the site of infection and inhibit bacterial growth - use of antimicrobial-impregnated wound dressings - use of silver as broad spectrum antimicrobial 21
  • 22. Advantage of topical antimicrobial use is : -lower cost than systemic therapy and ease of application -it will decrease bacterial load if applied properly -they are applied direct to wound bed – better to treat wounds with compromised circulation Disadvantage :- needs frequent application -sensitivity and allergic reactions - increased chance for microbes to become resistant 22
  • 23. 2. ANTISEPTIC AGENTS (ACETIC ACID, Antimicrobial solution CHLORHEXIDINE, HYDROGEN that prevents PEROXIDE, POVIDONE-IODINE) infection by killing microorganisms Previously were considered to reduce the rate of infection and speed wound repair Research showed that beside being broad-spectrum anti microbial, antiseptic agents are also cytotoxic to fibroblast, kerationcytes and neutrophyls ----------increse the duration of inflammatory response and delay epithelialization and wound contraction 23
  • 24. Used to decrease bacterial growth on inanimate objects Reduce bacterial concentrations on intact skin- used as surgical scrub Can be used for short period of time on open wounds e.g. patients with bite from animals in the farm can have short term use of povidone-iodine because this wounds are multimicrobial (Myers, 2008;p.104-113) 24
  • 25. 3.SYSTEMIC ANTIMICROBIAL THERAPY Prescribed for patients with sepsis or deep space infections , alone or in combination with topical antibiotics Advantage –reduce bacterial load, better patient compliance with treatment Disadvantage- more frequent and severe adverse reactions, development of resistant stains 25
  • 26. REVIEW: T- TISSUE MANAGEMENT DEBRIDMENT Sharp or surgical Autolytic Enzymatic Mechanical Biosurgery or larval therapy I- INFECTION/ INFLAMMATION 26
  • 27. M M MOIST WOUND HEALING Traditional theory says: “wounds should be kept dry and clean so that scab can form over the wound” Sussman,Bates- Jensen(2008) Practice shows that scab is a barrier to healing- because it interferes with moving of epithelial cells- poor cosmetic results and scarring The wounds should be managed in a moist environment so epithelial cells will be able to move Moist wound heals 3-5 times faster than dry wound because moist facilitates the three phases of wound healing process .Myers (2008) 27
  • 28. The amount of moisture is not known exactly- -a wound too dry will result in crust formation and will lack the enzymes and growth factors that facilitate healing -a wound that is to wet can delay healing because of the extra fluid around the wound which will produce maceration of tissue 28
  • 29. DRESSINGS -FUNCTION Create a moist wound environment - if wound too wet-dressing will absorb the excess exudate - if wound too dry- dressing will donate moisture to it Provide thermal insulation maintain temp.37- 38degrees C -this temp. increases oxygen saturation and decreases hemoglobin’s affinity for oxygen. 29
  • 30. -wound dressing should protect against infection - wound dressing should protect exposed nerve endings, decreasing the pain -provide hemostasis, edema control elimination of dead -dead space=void left by a wound cavity, undermining or tunneling---it must be avoided to prevent abscess formation and premature wound closure Provide gas exchange between wound and environment 30
  • 31. TYPES OF WOUND DRESSING PRIMARY DRESSING -Comes in direct contact with wound e.g.Band Eid SECONDARY DRESSING -Placed over primary dressing to improve protection e.g. Self-adhesive bandage placed over primary dressing 31
  • 32. CLINICAL DECISION MAKING MOST APPROPRIATE WOUND CARE - 32
  • 33. MOISTURE RETENTIVE DRESSING Maintain an ideal wound healing enviromnent Are specialized synthetic or organic dressings that are more occlusive than gauze Describes the ability of a dressing to transmit moisture ,vapor and gases from wound to atmosphere Have a lower moisture vapor transmission rate than gauze Allows patients to bathe, swim without contaminating the wound 33
  • 34. Maintain wound temperature better than gauze Protect the wound from trauma and infection Are adhesive---there is no need for secondary dressing Are elastic and stay in place for 3-7 days Stimulate granulation tissue formation, collagen synthesis and epithelialization Main risk for using moisture retentive dressing INFECTION TRAUMA TO THE WOUND BED MACERATION OF SURROUNDING SKIN 34
  • 35. 8 TYPES OF DRESSING 1.GAUZE DRESSING 2.IMPREGNATED GAUZE 3.SEMIPERMEABLE FILMS 4.SHEET HYDROGELS 5.SEMIPERMEABLE FOAMS 6.HYDROCOLLOIDS 7.ALGINATES 8.COMPOSITE DRESSINGS 35
  • 36. 1. . GAUZE DRESINGS WOVEN GAUZE- -made of cotton yarn or thread NONWOVEN GAUZE – -made of synthetic fibers pressed together (have grater absorbency) Loose weave gauze- aids in medical debridement but should not be placed over granulating tissue Gauze is highly permeable and nonocclusive and can be used as primary or secondary wound dressing 36
  • 37. MULTILAYER GAUZE DRESSINGS - Outer nonocclusive layer ----allows gas exchange - Middle antisher layer ---------moves with the patient - Nonadherent contact layer—allows absorbtion of exudates, reduces moisture less risk for maceration ANTIMICROBIAL-IMPREGNATED GAUZE - The use of such products should be limited ----reduce the potential of developing resistant microorganisms 37
  • 38. COMMON USES Both infected and noninfected wounds Large wounds or irregularly shaped Packing strips to prevent premature closure or keep away exudates in tunneling or underminig wounds CAN BE USED ALONE OR IN COMBINATION WITH ANTIBIOTICS, ENZYMES, GROWTH FACTORS, ALGINATES,SEMIPERMEABLE FOAMS OR FILMS 38
  • 39. PRECAUTINONS /CONTRAINDICATIONS 1.woven gauze require more force to remove---- potential wound trauma 2.woven gauze may leave residue to which body will respond by forming granuloma rolled gauze should be applied snuggly but without tension---to prevent a tourniquet like effect Telfa dressing---nonadherent, little absorption , keeps wound exudates close to wound---maceration of tissue 39
  • 40. 2 IMPREGNATED GAUZE DRESSING Mesh gauze non adherent, moderate occlusive, Impregnated with petrolatum, bismuth, zinc Petrolatum impregnated gauze might facilitate wound healing by decreasing trauma during dressing Can be used as contact layer on granulating wound beds, combined with secondary gauze dressing Used to burn wounds because have pain free removal 40
  • 41. PRECAUTIONS/CONTRAINDICATION S Bismuth (from xeroform dressings) is cytotoxic to inflammatory cells-----cause increased inflammatory response (not advisable for pt with venous insufficiency ulcer) Iodine-impregnated gauze cytotoxic to human cells only mild antimicrobial 41
  • 42. 3. SEMI PERMEABLE FILMS Thin flexible transparent sheets with adhesive backing Permeable to water vapor, O2, CO2 but impermeable to bacteria and water Have little absorptive capabilities , but are comfortable because of elasticity Should be applied without tension and wrinkles and can stay in place for 5-7 days Should NOT be used in cavity wounds or when heavy drainage is noted 42
  • 43. •COMMONLY USED FOR SUPERFICIAL WOUNDS (TEARS, LACERATIONS, ABRASIONS), INTRAVENOUS CATHETER SITES, AREAS OF FRICTION to prevent maceration ---apply on areas of intact skin -skin should not be oily or wet -if a channel or wrinkle forms----change dressing -NOT to be used on infected wounds 43
  • 44. 4. SHEET HYDROGELS 80-90% water or glycerin based wound dressing Absorb minimum amount of fluid by swelling Donate moisture to dry wounds Decrease pain by cooling the wound bed Are permeable to gas and water---less effective bacterial barrier 44
  • 45. PRECAUTIONS/CONTRAINDICATIONS Are not able to absorb heavy drainage Are absorbing very slowly----should not be used on bleeding wounds Require secondary dressing : USE minimal or moderate draining wound -can be used within casts or splints to decrease pressure - Effective at softening eschar to facilitate autolytic debridment 45
  • 46. 5. SEMIPERMEABLE FOAMS Made of polyurethaine, permeable to gas but not to bacteria have high moisture vapor transmission Provide thermal insulation Effective in treatment of stage II and III pressure ulcer 46
  • 47. - WOUNDS WITH MINIMAL AND HEAVY USES EXUDATES -GRANULATING OR SLOUGH COVERED PARTIAL AND FULL THICKNESS WOUND -SEMIPERMEABLE FOAMS –USED IN DONOR SITES , OSTOMY SITES, MINOR BURNS, DIABETIC ULCER PRECAUTIONS -Not recommended in dry or eschar-covered wounds -not indicated for arterial ulcers---because of enhancing dryness - Not indicated for area of high friction—heel ulcers 47
  • 48. 6.HYDROCOLLOIDS Contain hydrophilic colloid particles like gelatin, pectin, Have various absorption abilities Absolves exudates by swelling into a gel-like mass Provide thermal insulation to wound bed Impermeable to water, oxygen ,bacteria 48
  • 49. Uses- indicated for partial and full-thickness wounds -can be used on granular and necrotic wounds -used on minor burns, and pressure ulcers Duo Derm- effective barrier against urine, stool, MRSA, hepaB,HIV and Pseudomonas Arginosa 49
  • 50. 7. ALGINATES Contain salts of alginic acid from sea weeds and covered in calcium/sodium salts When placed on wound, it reacts with the serum and forms a hydrophilic gel Are highly permeable and non occlusive----require secondary dressing Stimulate macrophage activity Uses: highly draining wounds -partial and full-thickness wound -granular and eschar-covered wounds 50
  • 51. PRECAUTIONS/CONTRAINDICATIONS Not recommended for use on full thickness burns Not to be used on wounds with exposed tendon, joint capsule, bone Use with moisture barer to protect periwound skin from maceration 51
  • 52. 8. COMPOSITE DRESSING Multilayer dressing that can be used as primary or secondary wound dressings 3 layers 1. -inner contact-non adherent, prevents trauma to wound bed when dressing changes 2.-middle layer-absorbs moisture and keeps it away from wound bed to prevent maceration 3.-outer layer-bacterial barrier 52
  • 53. SILVER DRESSING -silver is antiseptic -dressings may be primary or secondary, adhesive or non-adhesive -release of silver ions----blue-black wound discoloration No evidence that silver is effective in presence of slough or eschar Silver is cytotoxic to fibroblast 53
  • 54. CHARCOAL DRESSING Key function of dressings is to control wound odor by absorbing odor producing gases released by bacteria---- --improve the quality of life for patients by allowing them to share with normal social activities 54
  • 55. SUMMARY MANAGING EXUDATES WITH DRESSING Type of wound Optimal dressing 0=dry Hydrogels, hydrocolloids, interactive wet dressings 1=minimum exudates Hydrogels, hydrocolloids, semipermeable films, calcium alginates 2= moderate exudates Calcium alginate, hydrofibre, hydrocolloid paste/powder, foams 3=heavy exudates Hydrofibre dressings, foam sheets/cavity, wound/ostomy bags 55
  • 56. WHEN CHOOSING TYPE OF DRESSING USED WE HAVE TO CONSIDER ALSO THE SURROUNDING SKIN EDGE ,EPITELIAL ADVANCEMENT E Signs of epithelial (edge) advancement 1. WB filled with granulating tissue. 2. Epithelialization at the wound margins. 56
  • 57. THE FOLLOWING QUESTIONS SHOULD BE ANSWERED PRIOR TO THE CLEANSING OF ANY WOUND: 1. What is the purpose of wound cleansing? 2. What method of wound cleansing would be most appropriate? 3. Does the wound require cleaning at each dressing change? 4. What type of wound cleansing product would be most appropriate? 57
  • 58. 1.THE PURPOSE OF WOUND CLEANSING: • Wound infection. • Excessive exudate. • Presence of foreign bodies, debris, eschar or slough. • A need to reduce contamination or devitalised tissue prior to suturing, in wounds healing by delayed primary intention (i.e. tertiary intention). 58
  • 59. DECIDING TO CLEANSE A WOUND SHOULD BE BASED ON THE FOLLOWING: • The size, shape and location of the patient’s wound. • The condition of the wound and stage of healing. • The availability and effectiveness of different methods of cleansing. • The availability and effectiveness of different cleansing agents. • The patient’s perceptions and needs 59
  • 60. CLEANSING TECHNIQUE • Clean versus sterile technique • Use of Normal saline and tap water • Hand washing is essential to reduce infection • Wound field concept • Dirty hand & clean hand 60
  • 61. IRRIGATION VS. SWABBING Swabbing the wound surface of a wound may mechanically dislodge loose, devitalised tissue but does not actively remove pathogens from the wound. Irrigation under pressure is an effective method of cleansing wounds that are infected or heavily contaminated. High pressure irrigation using a 30ml syringe and an 18-20G needle lowers the infection rates in contaminated wounds. 61
  • 62. STERILE VS.CLEAN TECHNIQUE Sterile technique -is defined as use of sterile equipment, ( gloves,wound dressing, instruments) in order to reduce exposure to microorganisms. -----------only sterile items may contact the pt’s wound, ------------use of sterile gloves and sterile field ------------meticulous set-up and maintenance of sterile field ( review table.6-8,p.117 text book) 62
  • 63. Clean technique- procedures that reduce overall number of microorganisms -------------------hand, washing, sterile instruments -------------------use of clean gloves and maintenance of clean field -------------------use clean hand dirty hand dressing procedure (see table 6- 10,p.117,text book) 63
  • 64. CONCLUSION OF RESEARCH - No difference in the rate of wound healing was found when comparing sterile with clean technique dressing -clean technique less expensive--- -clean technique----standard in wound management -sterile technique---reserved for wounds that require packing, severe burns, wounds of immunosupressed patients 64
  • 65. CLEANING AGENTS Antiseptics Antibiotics Honey Saline 0.9% Tap water 65
  • 66. ANTISEPTICS • Defined as a non-toxic disinfectant, which can be applied to skin or living tissues & has the ability to destroy vegetative compounds, such as bacteria, by preventing their growth. • If antiseptics are simply used to wipe across the wound surface, they will have little effect. • They need to be in contact with bacteria for about 20 min. before they actually destroy them. • They can applied in the form of soaks or incorporated into dressings, ointments, or creams. 66
  • 67. LOTIONS - ANTISEPTICS 1. Cetrimide 2. Chlorhexidine 3. Hydrogen Peroxide 4. Iodine 5. Potassium Permanganate 6. Proflavine 7. Silver 8. Sodium Hypochlorite
  • 68. LOTIONS - ANTISEPTICS 1. Cetrimide • Useful for its detergent properties, particularly for the initial cleansing of traumatic wounds or the removal of scabs & crusts in skin disease. • It is mostly only used in ER for initial cleansing of wounds rather than a routine cleanser • Two dangers should be noted: - Skin irritation & sensitivity - Very easy to become contaminated by bacteria, especially Pseudomonas aeruginosa. (Dealey, 2005)
  • 69. LOTIONS - ANTISEPTICS • It is available as a cream or as a lotion in combination with chlorhexidine. 69 (Dealey, 2005)
  • 70. LOTIONS - ANTISEPTICS 2. Chlorhexidine It is effective against G-ve & G+ve. It could maintain its antimicrobial levels for a period of time when impregnated into a dressing. However, its efficacy is rapidly diminished in the presence of organic material such as pus or blood. 70 (Dealey, 2005)
  • 71. LOTIONS - ANTISEPTICS It is more suitable for disinfection & hospital hygiene rather than wound care 71 (Dealey, 2005)
  • 72. LOTIONS - ANTISEPTICS 3. Hydrogen Peroxide 3% • Effective against anaerobes • It loses its effect when comes in contact with organic material such as pus or cotton gauze. • Cytotoxic to fibroblast unless diluted to a strength of 0.003%. This dilution is not effective against bacteria. But, this dilution still inhibits keratinocyte migration & proliferation. (Dealey, 2005)
  • 73. LOTIONS - ANTISEPTICS It is no longer widely used as there is no evidence to demonstrate its efficacy & there are number of other more alternatives. (Dealey, 2005)
  • 74. LOTIONS - ANTISEPTICS 4. Iodine • Broad-spectrum antiseptic • Used in wound care as povidine iodine 10% which contains 1% iodine. • Used as a skin disinfectant & to clean grossly infected wounds. • Effective against MRSA. (Dealey, 2005)
  • 75. LOTIONS - ANTISEPTICS Debate…? Lineaweaver et al. (1985) found that it is Cytotoxic to fibroblasts unless diluted to 0.001%, retards epithelialization & ↓ the tensile strength of the wound. However, Bennet et al. (2001) found that it significantly ↑ fibroblast proliferation slightly ↑ neodermal regeneration & epithelialization. (Dealey, 2005)
  • 76. LOTIONS - ANTISEPTICS • In 2003, Selvaggi et al., have reviewed & appraised the role of iodine & concluded that povidine iodine is an effective antibacterial that is superior to other products & has no problems with resistance. Iodine should not be used for the patients with thyroid disease or those who are sensitive to the product. 76 (Dealey, 2005)
  • 77. LOTIONS - ANTISEPTICS Povidine iodine is available in ointment, spray, & powder form & impregnated into dressings. Betadine 77 (Dealey, 2005)
  • 78. LOTIONS - ANTISEPTICS 5. Potassium Permanganate 0.01% • Used on heavily exuding wounds. • Generally, associated with leg ulceration. • Found in the form of tablets; to be dissolved in 4 L of water. (Dealey, 2005)
  • 79. LOTIONS - ANTISEPTICS 6. Proflavine • Has a mild bacteriostatic effect on G+ve, but no effect on G-ve. • It is available as a lotion 79 (Dealey, 2005)
  • 80. LOTIONS - ANTISEPTICS 7. Silver • Has a bactericidal effect on a wide range of bacteria (Dealey, 2005) Problem • It is extremely caustic, stains the skin black. • Prolonged use causes ↓Na, ↓K, & ↓Ca (Dealey, 2005) Solution • To overcome these problems → a cream, silver sulphadiazine, was developed → successful in controlling burn wound infections (Lansdown, 2004)
  • 81. LOTIONS - ANTISEPTICS Available in 3 modalities: • Liquid (Silver Nitrate) • Cream (Silver Sulphadiazine) • Silver-coated dressing (Dealey, 2005)
  • 82. LOTIONS - ANTISEPTICS 8. Sodium Hypochlorite Originally used in the 1st World War. Have few beneficial effects & do much harm. (Dealey, 2005)
  • 83. LOTIONS - ANTIBIOTICS • D’Arcy (1972) recommends that any antibiotic that is used systematically should not be applied to the skin. However, antibiotics that are not appropriate for systemic use may be developed for use on the skin or in wound care. • → creams, gels, ointments or impregnated dressings containing gentamicin, tetracycline, fusidic acid, or chlortetracycline. Should not be used as these antibiotics are used systematically (Dealey, 2005). • Mupirocin could be used for treatment of MRSA (Dealey, 2005)
  • 84. LOTIONS - ANTIBIOTICS • A range of antibiotics is available in topical form. • There is considerable risk of sensitization to the patient as well as the development of resistance organisms. • Systematic antibiotics are the treatment of choice when treating infected wounds. (Dealey, 2005)
  • 85. LOTIONS - HONEY Honey has been used in wound care since ancient times. Mole (1999) discussed the role of honey & its properties: Antibacterial action Deodirising action Debriding action Anti-inflammatory action Stimulation of wound healing Pain relief (Dunford & Hanano, 2004)
  • 86. LOTIONS – TAP WATER • Is being used more frequently on wound areas already colonized such as wounds following rectal surgery of foot ulcer. • Using tap water to clean wounds did not differ from using sterile normal saline in respect of wound infection and healing rates. (Fernandez, Griffiths, & Ussia, 2002) 86
  • 87. LOTIONS – SALINE 0.9% • The only completely safe cleansing agent & is the treatment of choice for use of most wounds. • It is used in conjunction with many of the modern products. • It is presented in sachets, small plastic containers, & aerosols. (Dealey, 2005)
  • 88. REVISION OF DRESSING TYPES 1. Inert non-stick dressings Gauze Paraffin tulle dressings (Jelonet®, Bactigras®) Non-paraffin, non-tulle, woven products, (e.g. Adaptic®, Inadine®) Non-stick dressings (e.g. Melolin®, Cutilin®) Combine Primary dressing: • Protective low absorption dressing (Carville, 2005; Dealey, 2005)
  • 89. DRESSING TYPES REVIEW Application: • Clean wound base • Place shiny side of dressing to wound. • May require soaking if exudate strikethrough has occurred. Contraindications/Possible Side effects: • Harsh debridement of the wound bed if exudate dries • Limited use as a primary dressing • Dries out the wound bed (Carville, 2005; Dealey, 2005)
  • 90. DRESSING TYPES REVIEW 2. Film dressing Opsite Flexigrid® Opsite Post-Op® Tegaderm® Polyskin® Primary and secondary dressing: • Low exudating wounds, protective dressing. (Carville, 2005; Dealey, 2005)
  • 91. Application: • Clean wound base • Prepare peri-wound area with a protective barrier wipe. • Apply adhesive side to wound and remove outer layer. • Adhesive strongest in first 24 hours; can remain for 7 days. • Observe for maceration, remove if this occurs. Contraindications/ Possible Side effects: • Do not apply to infected wounds or if allergic to tapes. • NB: Green sided Opsite is for wounds, orange sided Opsite is for vascular access devices. 91 (Carville, 2005; Dealey, 2005)
  • 92. DRESSING TYPES REVIEW 3. Foam dressings Allevyn® Allevyn Adhesive® Allevyn Cavity® Cavi-Care® Primary and secondary dressing: • Light/mod/highly exudating wounds, protective dressing, cavity wounds. 92 (Carville, 2005; Dealey, 2005)
  • 93. Application: • Clean wound base • Read packaged for insertion side (patterned or shiny side up) • Sheet foam left insitu up to 7 days (24 hours if infected) • Cavity foams left insitu up to 14 days (daily washing of foam if infected) Contraindications/ Possible Side effects: • Avoid covering with occlusive dressings. • Avoid wounds dressed with antibacterial solutions. 93 (Carville, 2005; Dealey, 2005)
  • 94. DRESSING TYPES REVIEW 4. Hydrogel dressings Solugel® Intra site® Gel Solosite® Gel Clear-Site® Duoderm® Gel Aquaflo® Primary dressing: • Slough or necrotic wounds requiring chemical debridement. • Light/moderate exudating wounds, hydrate dry wounds. 94 (Carville, 2005; Dealey, 2005)
  • 95. 5. Hydrocolloid dressings Duoderm Extra Thin® Duoderm CGF® Duoderm® Paste Comfeel Plus Transparent® Comfeel Plus® Contour Dressing Comfeel Plus® Pressure Relieving Dressing Comfeel® Paste Comfeel® Powder Primary and secondary dressing: • Slough wounds requiring autolytic debridement, low/moderate exudating wounds. 95 (Carville, 2005; Dealey, 2005)
  • 96. Application: • Clean wound base, wipe peri-wound with barrier wipe. • Warm product in hands to activate adhesive. • Place adhesive side to wound. • Leave at least 2 cm border around wound. • Can be left insitu up to 7 days, dependant on exudate level. • Dressing becomes opaque when due for change. Contraindications/ Possible Side effects: • Do not apply to infected wounds or if client is allergic. • Remove if patient complains of discomfort. 96 (Carville, 2005; Dealey, 2005)
  • 97. WOUND DRESSINGS REVIEW 6. Alginate dressings Kaltostat® Algoderm® Sorbsan® Curasorb® Kaltocarb® Primary dressing: • Heavily exudating, bleeding, slough or infected wounds. 97 (Carville, 2005; Dealey, 2005)
  • 98. Application: • Clean wound base • Lightly pack or line the wound, product swells with exudate. • Avoid pre-moistening the product. • Discontinue use if the dressing remains dry. • Can be left insitu up to 4 days, dependant on exudate level. • Requires a secondary dressing. Contraindications/ Possible Side effects: • Do not use on dry wounds as it dehydrates the wound bed. 98 (Carville, 2005; Dealey, 2005)
  • 99. WOUND DRESSING REVIEW 7. Hydrofiber dressings Aquacel Primary dressing: • Heavily exudating or infected wounds. 99 (Carville, 2005; Dealey, 2005)
  • 100. Application: • Clean wound base. • Line the wound base with product. • Cover with a secondary dressing. • Can be left insitu up to 7 days, dependant on exudate level. Contraindications/ Possible Side effects: • Heavily infected wounds require Hydrofiber impregnated with Silver. • Do not use in people allergic to hydrocolloids. 100 (Carville, 2005; Dealey, 2005)
  • 101. WOUND DRESSING REVIEW 8. Non-crystalline Silver dressings Acticoat® Aquacel Ag® Actisorb plus® (charcoal) Primary dressing: • Infected wounds (150 pathogens including MRSA and VRE), burns, donor and recipient sites. 101 (Carville, 2005; Dealey, 2005)
  • 102. Application: • Clean wound base. • Moisten product with sterile water, daily if not enough exudate. • Cut to wound size and shape, apply blue side down. • Cover with a secondary dressing. • Can be left insitu up to 7 days, dependant on exudate level. Contraindications/ Possible Side effects: • Do not use on people going for a Magnetic Resonance Imaging. • Do not use in people allergic to silver. 102 (Carville, 2005; Dealey, 2005)
  • 103. WOUND DRESSING REVIEW 9. Zinc dressings Steripaste® Viscopaste® Flexidress® Gelocast® Primary dressing: • Slough wounds, epithelializing wounds and to protect limbs at risk of skin tears or degloving. 103 (Carville, 2005; Dealey, 2005)
  • 104. Application: • Cut length as required, usually 3-4 times the size of the wound . • Fold to make a patch and place over wound. • Requires a secondary dressing. • Can be left insitu up to 7 days. Contraindications/Possible Side effects: • Allergy to zinc 104 (Carville, 2005; Dealey, 2005)
  • 105. WOUND MANAGEMENT PRODUCTS 10. Other dressings Cadexomer Iodine Vacuum assisted closure (VAC) 105 (Carville, 2005; Dealey, 2005)
  • 106. REFERENCES Schultz, G.S., Sibbald, R.G., Falanga, V., Ayello, E.A., Dowsett, C., Harding, K., Romanelli, M., Stacey, M.C., Teot, L., Vanscheidt, W. (2003) Wound bed preparation: a systematic approach to wound management. Wound Repair and Regeneration, 11(2), S1-S28. Watret, L. (2005). Teaching wound management: a collaborative model for future education. Retrieved 6 September 2009, from World Wound Wide: http://www.worldwidewounds.com/2005/november/Watret/T eaching-Wound-Mgt-Collaborative-Model.html 106
  • 107. REFERENCES Falanga, V. (2000). Classification for wound bed preparation and stimulation of chronic wounds. Wound Repair and Regeneration, 8(5), 347-352. Falanga, V. (2004). Wound bed preparation: science applied to practice, in European Wound Management Association (EWMA) Position Document, Wound Bed Preparation in Practice, London: MEP Ltd. Lansdown, A.B.G. (2004). A review of the use of silver in wound care: facts and fallacies. British Journal of Nursing, 13(6), S6-S19. Lineaweaver, W., Howard, R., Soucy, D., McMorris, S., 107 Freeman, J., Crain, C., Robertson, J., & Rumley, T. (1985). Topical antimicrobial toxicity. Archives of Surgery, 120, 267-270.
  • 108. REFERENECE Myers,A.B, (2008).Wound management. Principles and practice.(2nd ed.)Pearson Education Australia PTY.( pp.71-155) Bennett, L.L., Rosenblum, R.S., Perlov, C., Davidson, J.M., Barton, R.M., & Nannet, L.B. (2001). An in vivo comparison of topical agents in wound repair. Plastic and reconstructure surgery, 108(3), 674-685. Carville, K, (2005). Wound Care Manual (5th ed.). Osborne Park, Australia: Silver Chain. D’Arcy, P.F. (1972). Drugs on the skin: a clinical and pharmaceutical problem. Pharmaceutical Journal, 209, 491-492. Dealey, C. (2005). The Care of Wounds: A Guide for Nurse (3rd ed.). Oxford, UK: Blackwell Publishing. 108 Fernandez, R., Griffiths, R., Ussia, C. (2002). Water for wound cleansing. Cochrane Database Systematic Review, 4.