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How is variation produced in
       a population?

        Jennifer Oh (SL)
What is genetic variation?
What is genetic variation?

Variation in alleles of
genes
What is genetic variation?

Variation in alleles of
genes

Occurs within and
among populations
What is genetic variation?

Variation in alleles of
genes

Occurs within and
among populations

The “raw material” of
natural selection
Sources of Genetic Variation
Sources of Genetic Variation
                 Mutations
Sources of Genetic Variation
                 Mutations

                   Gene mutations
Sources of Genetic Variation
                 Mutations

                   Gene mutations

                   Chromosome
                   mutations
Sources of Genetic Variation
                 Mutations

                   Gene mutations

                   Chromosome
                   mutations

                 Sexual Reproduction
Sources of Genetic Variation
                 Mutations

                   Gene mutations

                   Chromosome
                   mutations

                 Sexual Reproduction

                   Recombination
Sources of Genetic Variation
                 Mutations

                   Gene mutations

                   Chromosome
                   mutations

                 Sexual Reproduction

                   Recombination

                   Mate selection
Assessment Statements
These are the assessment statements that
deal with this topic:
Assessment Statements
These are the assessment statements that
deal with this topic:
  4.1.2                   Define gene, allele, and genome

  4.1.3                        Define gene mutation

           State that meiosis is a reduction division of a diploid nucleus
  4.2.1                       to form haploid nuclei
              Outline the process of meiosis, including pairing of
  4.2.3   homologous chromosomes and crossing over, followed by t wo
                 divisions, which results in four haploid cells
          Define genotype, phenotype, dominant allele, recessive allele,
  4.3.1   codominant alleles, locus, homozygous, heterozygous, carrier
                                  and test cross
Basic Vocabulary
Basic Vocabulary

Before diving into the details of genetic
variation, here are some basic terms that you
need to know for this topic.
Basic Vocabulary

Before diving into the details of genetic
variation, here are some basic terms that you
need to know for this topic.
     From assessment statement 4.1.2
Basic Vocabulary

Before diving into the details of genetic
variation, here are some basic terms that you
need to know for this topic.
     From assessment statement 4.1.2
          Gene, Allele, Genome
Basic Vocabulary

Before diving into the details of genetic
variation, here are some basic terms that you
need to know for this topic.
     From assessment statement 4.1.2
          Gene, Allele, Genome
     From assessment statement 4.3.1
Basic Vocabulary

Before diving into the details of genetic
variation, here are some basic terms that you
need to know for this topic.
     From assessment statement 4.1.2
          Gene, Allele, Genome
     From assessment statement 4.3.1
          Genotype, phenotype
4.1.2 Vocab
4.1.2 Vocab

Gene - a heritable factor that controls a
specific characteristic
4.1.2 Vocab

Gene - a heritable factor that controls a
specific characteristic
4.1.2 Vocab

Gene - a heritable factor that controls a
specific characteristic
4.1.2 Vocab

Gene - a heritable factor that controls a
specific characteristic
Allele - one specific form of a gene, differing
from other alleles by one or a few bases only
and occupying the same gene locus as other
alleles of the gene
4.1.2 Vocab

Gene - a heritable factor that controls a
specific characteristic
Allele - one specific form of a gene, differing
from other alleles by one or a few bases only
and occupying the same gene locus as other
alleles of the gene
4.1.2 Vocab

Gene - a heritable factor that controls a
specific characteristic
Allele - one specific form of a gene, differing
from other alleles by one or a few bases only
and occupying the same gene locus as other
alleles of the gene
4.1.2 Vocab

Gene - a heritable factor that controls a
specific characteristic
Allele - one specific form of a gene, differing
from other alleles by one or a few bases only
and occupying the same gene locus as other
alleles of the gene
Genome - the whole genetic information of
an organism
4.3.1 Vocab
4.3.1 Vocab

Genotype - the alleles of an organism;
determines the genetic potential
4.3.1 Vocab

Genotype - the alleles of an organism;
determines the genetic potential
Phenotype - the characteristics of an
organism
Mutation
Mutation
Mutations are the source of all new genetic information
Mutation
Mutations are the source of all new genetic information
Not always harmful, some are neutral or beneficial
Mutation
Mutations are the source of all new genetic information
Not always harmful, some are neutral or beneficial
Can be accumulated over many generations
Mutation
Mutations are the source of all new genetic information
Not always harmful, some are neutral or beneficial
Can be accumulated over many generations
Gene mutation (4.1.3)
Mutation
Mutations are the source of all new genetic information
Not always harmful, some are neutral or beneficial
Can be accumulated over many generations
Gene mutation (4.1.3)
    Change in the base sequence of an allele
Mutation
Mutations are the source of all new genetic information
Not always harmful, some are neutral or beneficial
Can be accumulated over many generations
Gene mutation (4.1.3)
    Change in the base sequence of an allele
Chromosome mutation
Mutation
Mutations are the source of all new genetic information
Not always harmful, some are neutral or beneficial
Can be accumulated over many generations
Gene mutation (4.1.3)
    Change in the base sequence of an allele
Chromosome mutation
    Pieces of chromosomes may be rearranged during
    meiosis
Mutation
Sexual Reproduction
Sexual Reproduction
Provides rearrangement and shuffling of the genetic
material into new combinations
Sexual Reproduction
Provides rearrangement and shuffling of the genetic
material into new combinations
Crossing over - Recombination
Sexual Reproduction
Provides rearrangement and shuffling of the genetic
material into new combinations
Crossing over - Recombination
    Pieces of chromosome are often exchanged with a
    chromosome’s homologue
Sexual Reproduction
Provides rearrangement and shuffling of the genetic
material into new combinations
Crossing over - Recombination
    Pieces of chromosome are often exchanged with a
    chromosome’s homologue
    Increases shuffling of allele combinations
Sexual Reproduction
Provides rearrangement and shuffling of the genetic
material into new combinations
Crossing over - Recombination
    Pieces of chromosome are often exchanged with a
    chromosome’s homologue
    Increases shuffling of allele combinations
Mate Selection
Sexual Reproduction
Provides rearrangement and shuffling of the genetic
material into new combinations
Crossing over - Recombination
    Pieces of chromosome are often exchanged with a
    chromosome’s homologue
    Increases shuffling of allele combinations
Mate Selection
    Different combinations of genes will come together
    in the offspring depending on which t wo parents
    mate together
Meiosis
Meiosis

Meiosis is a reduction division of a diploid nucleus to form
haploid nuclei (4.2.1)
Meiosis

Meiosis is a reduction division of a diploid nucleus to form
haploid nuclei (4.2.1)
For this topic, the important part is: crossing over
Meiosis

Meiosis is a reduction division of a diploid nucleus to form
haploid nuclei (4.2.1)
For this topic, the important part is: crossing over
At Prophase I, the homologous chromosomes pair up
(synapsis), and segments of the chromosome can be
exchanged
Meiosis

Meiosis is a reduction division of a diploid nucleus to form
haploid nuclei (4.2.1)
For this topic, the important part is: crossing over
At Prophase I, the homologous chromosomes pair up
(synapsis), and segments of the chromosome can be
exchanged
Important source of variation for the gene pool of a
population
Watch this video!



GREAT video lesson about genetic variation:
http://www.khanacademy.org/video/
variation-in-a-species?playlist=Biology
i-Biology Link

4.1 Presentation
   http://i-biology.net/?s=4.1
4.2 Presentation
   http://i-biology.net/?s=4.2
4.3 Presentation
   http://i-biology.net/?s=4.3
More exercises


For more exercises on this topic, look at these
pages from the Biozone workbook.
     Mutations: p. 197 - 8
     Meiosis: p. 185 - 8
     Genetic Variation: p. 181 - 2
The End!

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B variation jennifer

  • 1. How is variation produced in a population? Jennifer Oh (SL)
  • 2. What is genetic variation?
  • 3. What is genetic variation? Variation in alleles of genes
  • 4. What is genetic variation? Variation in alleles of genes Occurs within and among populations
  • 5. What is genetic variation? Variation in alleles of genes Occurs within and among populations The “raw material” of natural selection
  • 6. Sources of Genetic Variation
  • 7. Sources of Genetic Variation Mutations
  • 8. Sources of Genetic Variation Mutations Gene mutations
  • 9. Sources of Genetic Variation Mutations Gene mutations Chromosome mutations
  • 10. Sources of Genetic Variation Mutations Gene mutations Chromosome mutations Sexual Reproduction
  • 11. Sources of Genetic Variation Mutations Gene mutations Chromosome mutations Sexual Reproduction Recombination
  • 12. Sources of Genetic Variation Mutations Gene mutations Chromosome mutations Sexual Reproduction Recombination Mate selection
  • 13. Assessment Statements These are the assessment statements that deal with this topic:
  • 14. Assessment Statements These are the assessment statements that deal with this topic: 4.1.2 Define gene, allele, and genome 4.1.3 Define gene mutation State that meiosis is a reduction division of a diploid nucleus 4.2.1 to form haploid nuclei Outline the process of meiosis, including pairing of 4.2.3 homologous chromosomes and crossing over, followed by t wo divisions, which results in four haploid cells Define genotype, phenotype, dominant allele, recessive allele, 4.3.1 codominant alleles, locus, homozygous, heterozygous, carrier and test cross
  • 16. Basic Vocabulary Before diving into the details of genetic variation, here are some basic terms that you need to know for this topic.
  • 17. Basic Vocabulary Before diving into the details of genetic variation, here are some basic terms that you need to know for this topic. From assessment statement 4.1.2
  • 18. Basic Vocabulary Before diving into the details of genetic variation, here are some basic terms that you need to know for this topic. From assessment statement 4.1.2 Gene, Allele, Genome
  • 19. Basic Vocabulary Before diving into the details of genetic variation, here are some basic terms that you need to know for this topic. From assessment statement 4.1.2 Gene, Allele, Genome From assessment statement 4.3.1
  • 20. Basic Vocabulary Before diving into the details of genetic variation, here are some basic terms that you need to know for this topic. From assessment statement 4.1.2 Gene, Allele, Genome From assessment statement 4.3.1 Genotype, phenotype
  • 22. 4.1.2 Vocab Gene - a heritable factor that controls a specific characteristic
  • 23. 4.1.2 Vocab Gene - a heritable factor that controls a specific characteristic
  • 24. 4.1.2 Vocab Gene - a heritable factor that controls a specific characteristic
  • 25. 4.1.2 Vocab Gene - a heritable factor that controls a specific characteristic Allele - one specific form of a gene, differing from other alleles by one or a few bases only and occupying the same gene locus as other alleles of the gene
  • 26. 4.1.2 Vocab Gene - a heritable factor that controls a specific characteristic Allele - one specific form of a gene, differing from other alleles by one or a few bases only and occupying the same gene locus as other alleles of the gene
  • 27. 4.1.2 Vocab Gene - a heritable factor that controls a specific characteristic Allele - one specific form of a gene, differing from other alleles by one or a few bases only and occupying the same gene locus as other alleles of the gene
  • 28. 4.1.2 Vocab Gene - a heritable factor that controls a specific characteristic Allele - one specific form of a gene, differing from other alleles by one or a few bases only and occupying the same gene locus as other alleles of the gene Genome - the whole genetic information of an organism
  • 30. 4.3.1 Vocab Genotype - the alleles of an organism; determines the genetic potential
  • 31. 4.3.1 Vocab Genotype - the alleles of an organism; determines the genetic potential Phenotype - the characteristics of an organism
  • 33. Mutation Mutations are the source of all new genetic information
  • 34. Mutation Mutations are the source of all new genetic information Not always harmful, some are neutral or beneficial
  • 35. Mutation Mutations are the source of all new genetic information Not always harmful, some are neutral or beneficial Can be accumulated over many generations
  • 36. Mutation Mutations are the source of all new genetic information Not always harmful, some are neutral or beneficial Can be accumulated over many generations Gene mutation (4.1.3)
  • 37. Mutation Mutations are the source of all new genetic information Not always harmful, some are neutral or beneficial Can be accumulated over many generations Gene mutation (4.1.3) Change in the base sequence of an allele
  • 38. Mutation Mutations are the source of all new genetic information Not always harmful, some are neutral or beneficial Can be accumulated over many generations Gene mutation (4.1.3) Change in the base sequence of an allele Chromosome mutation
  • 39. Mutation Mutations are the source of all new genetic information Not always harmful, some are neutral or beneficial Can be accumulated over many generations Gene mutation (4.1.3) Change in the base sequence of an allele Chromosome mutation Pieces of chromosomes may be rearranged during meiosis
  • 42. Sexual Reproduction Provides rearrangement and shuffling of the genetic material into new combinations
  • 43. Sexual Reproduction Provides rearrangement and shuffling of the genetic material into new combinations Crossing over - Recombination
  • 44. Sexual Reproduction Provides rearrangement and shuffling of the genetic material into new combinations Crossing over - Recombination Pieces of chromosome are often exchanged with a chromosome’s homologue
  • 45. Sexual Reproduction Provides rearrangement and shuffling of the genetic material into new combinations Crossing over - Recombination Pieces of chromosome are often exchanged with a chromosome’s homologue Increases shuffling of allele combinations
  • 46. Sexual Reproduction Provides rearrangement and shuffling of the genetic material into new combinations Crossing over - Recombination Pieces of chromosome are often exchanged with a chromosome’s homologue Increases shuffling of allele combinations Mate Selection
  • 47. Sexual Reproduction Provides rearrangement and shuffling of the genetic material into new combinations Crossing over - Recombination Pieces of chromosome are often exchanged with a chromosome’s homologue Increases shuffling of allele combinations Mate Selection Different combinations of genes will come together in the offspring depending on which t wo parents mate together
  • 49. Meiosis Meiosis is a reduction division of a diploid nucleus to form haploid nuclei (4.2.1)
  • 50. Meiosis Meiosis is a reduction division of a diploid nucleus to form haploid nuclei (4.2.1) For this topic, the important part is: crossing over
  • 51. Meiosis Meiosis is a reduction division of a diploid nucleus to form haploid nuclei (4.2.1) For this topic, the important part is: crossing over At Prophase I, the homologous chromosomes pair up (synapsis), and segments of the chromosome can be exchanged
  • 52. Meiosis Meiosis is a reduction division of a diploid nucleus to form haploid nuclei (4.2.1) For this topic, the important part is: crossing over At Prophase I, the homologous chromosomes pair up (synapsis), and segments of the chromosome can be exchanged Important source of variation for the gene pool of a population
  • 53. Watch this video! GREAT video lesson about genetic variation: http://www.khanacademy.org/video/ variation-in-a-species?playlist=Biology
  • 54. i-Biology Link 4.1 Presentation http://i-biology.net/?s=4.1 4.2 Presentation http://i-biology.net/?s=4.2 4.3 Presentation http://i-biology.net/?s=4.3
  • 55. More exercises For more exercises on this topic, look at these pages from the Biozone workbook. Mutations: p. 197 - 8 Meiosis: p. 185 - 8 Genetic Variation: p. 181 - 2

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