This Dental School crossover clinical study found propolis toothpaste to be safe and effective in reducing plaque accumulation when compared to Miswak and Colgate total toothpaste. Propolis in the field of dentistry is tough. It responds very well when in contact with mucous linings of the body. This super antioxidant also delivers antimicrobial, antifungal and antiseptic properties which make it very adaptable to numerous conditions found out of balance.