4. We recommend either short - term mole monitoring
or a biopsy for these lesions, depending on the
clinician’s level of experience.
Nevi Malignant
Melanoma
6. Malignant Patterns
* Global Evaluation of Lesion
Color: Generally more than
3 colors
Reticular
Brown Blue
White Gray
Black Red
Asymmetry:
Refers to the non-
uniform distribution of colors and
Homogeneous Globular structures on either side of the
axis and not by lesion shape.
Disorganization:
Non-uniformity of
structures and their departure
from the expected locations
traditionally seen in benign
* Adapted from Hofmann-Wellenhof R, Blum A, Wolff IH,
Soyer HP et al (2001) Arch Dermatol 137: 1575-1580 lesions.
7. Malignant Patterns
A pattern is created by the placement of structures in a
lesion. When these structures are asymmetrically distributed
and there are more than 3 colors noted, they create patterns
seen in many malignant lesions.
Reticular Globular Homogenous
disorganized disorganized disorganized
