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PREVENTION OF COMMON ENDEMIC
NOSOCOMIAL INFECTIONS

Mr. Jithin Raj
Hospital Infection Control Nurse
Padmavathy Medical Foundation
Nosocomial Infections:
NSI also called Hospital Acquired
Infection are infections acquired during
hospital care which are not present or
incubating at or incubating at admission.




Infections occurring more than 48 hrs
after admission are usually considered
nosocomial.
The four most nosocomial infections are:
 Urinary

Tract Infections
 Surgical wound Infections
 Pneumonia
 Primary blood stream infection
Urinary Tract Infections

 The

most frequent nosocomial infections
 80% of these infections are associated
with an indwelling urethral catheter
Interventions effective in preventing
nosocomial UTI;
Avoiding urethral catheterization unless there is a compelling indication
 Limiting the duration of drainage
 Maintaining aseptic practice during urinary catheter insertion and other
urological procedure
 Non – traumatic urethral insertion using an appropriate lubricant
 Maintaining a clossed drainage system

Sterile gloves for insertion
Perineal cleaning with an antiseptic solution prior
to insertion
Hygienic handwash / rub prior to the insertion and
following catheter drainage bag manipulation
Other practices which are recommended,
but not proven to decrease infection
include:
Maintaining good patient hydration
 Appropriate perineal hygiene for the patients with
catheters
 Appropriate staff training in catheter insertion and care
 Maintaining unobstructed drainage of the bladder to the
collection bag, with the bag below the level of the
bladder

Generally, the smallest diameter
catheter diameter should be used.
Catheter material (latex, silicone)
does not influence infection rates
For patients with a neurogenic bladder:



Avoid indwelling catheter if possible
If assisted bladder drainage is necessary, clean
intermittent urinary catheterization should be
used.
Surgical wound infections
(Surgical Site Infections)
Factors which influence the frequency of
surgical wound infection include:








Surgical technique
Extent of endogenous contamination of the
wound at surgery
(eg. Clean, clean – condaminated)
Duration of operation
Underlying patient status
Operating room environment
Organism shed by the operating room team
A systematic programme for prevention of
surgical wound infections includes with
the practice of optimal surgical technique
and;
1.
2.
3.

4.
5.

Operating room environment
Operating room staff
Pre – intervention preparation of the patient
Antimicrobial prophylaxis
Surgical wound surveillance
1. Operating room
environment
Recommended cleaning schedule:
 Every

morning before any intervention
 Between procedures
 At the end of the working day
 Once a week
2. Operating room staff

Handwashing
Operating room attire
Operating room activity

3. Pre – intervention
preparation of the patient
4. Antimicrobial prophylaxis


Antibiotics must be initiated intravenously within
one hour prior to the intervention



In most cases, prophylaxis with a single
preoperative dose is sufficient



Administration of prophylactic antibiotics for a
longer period prior to the operation is
counterproductive, as there will be a risk of
infection by a resistant pathogen
“ANTIBIOTIC PROPHYLAXIS IS NOT A SUBSTITUTE FOR
APPROPRIATE ASEPTIC SURGICAL PRACTICE”
5. Surgical wound
surveillance
NOSOCOMIAL RESPIRATORY
INFECTIONS


Ventilator-associated pneumonia (VAP),
defined as pneumonia occurring >48 - 72
hours after endotracheal intubation, is the
most common and fatal nosocomial infection
of intensive care.



VAP is associated with increased mortality
and
morbidity,
increased
duration
of
mechanical ventilation, prolonged intensive
care unit and hospital stay, and increased
cost of hospitalisation.
Diagnosis (The Centers for Disease
Control Guidelines criteria)

Depends on a combination of;
 Clinical signs
 Impaired gas exchange,
 Radiological changes
 Positive microscopic analysis
Recommendations to prevent
these infections include;
VAP in the ICUs:






Appropriate disinfection and in-use care
of tubing, respirators, and humidifiers to
limit contamination
No routine changes of respiratory tubing
Avoid antacids and H2 blockers
Head up position
Sterile tracheal suctioning
Medical Units
Limit medications which impair
consciousness
 Position comatose patients to limit the
potential for aspiration
 Avoid oral feeds in patients with
swallowing abnormalities
 Prevent exposure of neutropenic or
transplant patients to fungal spores
during construction or renovation

Surgical units


All invasive devices used during anaesthesia must be
sterile



Anaesthetist must use gloves and masks when undertaking
invasive tracheal or venous or epidural care



Disposable filters (for individual use) for ET intubation
effectively prevent the transmission of microorganism
among patients by ventilators



Preoperative physiotherapy prevents postoperative
pneumonia in patients with chronic respiratory disease.
Neurological patients with tracheostomy
(with or without ventilation)
Sterile suctioning in appropriate frequency
 Appropriate cleaning and disinfection of
respiratory machines and other devices.
 Physiotherapy to assist with drainage of
secretions.

INFECTIONS ASSOCIATED WITH
INTRAVASCULAR LINES
Key practices for all vascular catheters includes;


Avoiding catheterization unless there is a medical indication



Maintaining a high level of asepsis for catheter insertion
and care



Limiting the use of catheters to as short a duration as
possible



Preparing fluids aseptically and immediately before use



Training of personnel in catheter insertion and care
Portal of entry for microorganisms in IV
System









During manufacture
Additives
Hairline cracks/ punctures
Bottle – tubing junction
Medication port
Stopcock
Insertion site
Secondary infection from other side
Interventions for –
Peripheral vascular catheters


Hands must be washed before all catheters care,
using hygienic handwash or rub



Wash and disinfect skin at the insertion site with an
antiseptic solution



IV line changes no more frequetly than changes after
the transfusion of blood or intralipids, and for
discontinuous perfusions



A dressing change is not normally necessary



If local infection or phlebitis occurs, the catheter
should be removed immediately
Central Vascular catheters


Clean the insertion site with an antiseptic solution



Do not apply solvents or antimicrobial ointment to the
insertion site



Mask, cap and sterile gloves and gown must be worn
for insertion



The introduction of the catheter and the subsequent
catheter dressings require a surgical handwash or rub



Follow appropriate aseptic care in accessing the
system, including disinfecting external surfaces of
hub and ports


Change of lines should normally not occur
more often than once every three days



Change of dressing at the time of the change
of lines, following surgical asepsis



Do not replace over a guide wire if infection
is suspected



Antimicrobial impregnated catheters may
decrease infection in high – risk patients with
short – term catheterization
Sterile gauze or transparent
dressing to cover the catheter site
An increase number of catheter lumen
may increase the risk of infection
Use the subclavion
site in preference
to jugular or
femoral sites
Consider using a peripherally
inserted central catheter, if
appropriate
Central vascular totally implanted catheters
Implantable vascular access devices should
be considered for patients who require
long – term therapy.
Preventive practices include;


A pre operative shower and implantation under surgical
conditions in an operating room



Local preparation includes washing and antisepsis with major
antiseptic solution as for other surgical procedures



All PPEs must be worn



Requires strict hand wash prior to procedure



Maintain a closed system during the use of the device.



A change of lines should normally occur every 5 days for
continuous use
Hand decontamination…..
IMPORTANCE OF HANDWASHING..
Compliance with handwashing, however, is
frequently sub optimal, due to;


Lack of accessible equipment



High staff – to – patient ratios



Allergies to handwashing products



Insufficient knowledge of staff about risks and
procedures



Too long a duration recommended for washing
Optimal hand hygiene requirements
For handwashing;
Running water
 Products
 Facilities for drying

For hand disinfection;
 Specific hand disinfectants
Procedures
Jewellary must be removed before
handwashing
 Simple hygienic procedures may limited to
hands and wrists
 Surgical procedures include the hand and
forearm

Routine care
(minimal)

Antiseptic
handcleaning
(moderate) –
aseptic care of
infected patients

Surgical scrub
(surgical care)

1 minute

3-5 minutes

With non – antiseptic
soap

With antiseptic soap

With antiseptic soap

Quick hygienic hand
disinfection
(by rubbing) with
alcoholic rub.

Quick hygienic hand
disinfection
(by rubbing) with
alcoholic rub.

Simple handwash and
drying followed by
two applications of
hand disinfectant,
then rub to dry
5 MOMENTS OF HANDWASHING…
Steps of handwashing..
Prevention Of Endemic Nosocomial infection and Hand washing by Mr. Jithin
Prevention Of Endemic Nosocomial infection and Hand washing by Mr. Jithin

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Prevention Of Endemic Nosocomial infection and Hand washing by Mr. Jithin

  • 1.
  • 2. PREVENTION OF COMMON ENDEMIC NOSOCOMIAL INFECTIONS Mr. Jithin Raj Hospital Infection Control Nurse Padmavathy Medical Foundation
  • 3. Nosocomial Infections: NSI also called Hospital Acquired Infection are infections acquired during hospital care which are not present or incubating at or incubating at admission.   Infections occurring more than 48 hrs after admission are usually considered nosocomial.
  • 4. The four most nosocomial infections are:  Urinary Tract Infections  Surgical wound Infections  Pneumonia  Primary blood stream infection
  • 5. Urinary Tract Infections  The most frequent nosocomial infections  80% of these infections are associated with an indwelling urethral catheter
  • 6. Interventions effective in preventing nosocomial UTI; Avoiding urethral catheterization unless there is a compelling indication  Limiting the duration of drainage  Maintaining aseptic practice during urinary catheter insertion and other urological procedure  Non – traumatic urethral insertion using an appropriate lubricant  Maintaining a clossed drainage system 
  • 7. Sterile gloves for insertion
  • 8. Perineal cleaning with an antiseptic solution prior to insertion
  • 9. Hygienic handwash / rub prior to the insertion and following catheter drainage bag manipulation
  • 10. Other practices which are recommended, but not proven to decrease infection include: Maintaining good patient hydration  Appropriate perineal hygiene for the patients with catheters  Appropriate staff training in catheter insertion and care  Maintaining unobstructed drainage of the bladder to the collection bag, with the bag below the level of the bladder 
  • 11. Generally, the smallest diameter catheter diameter should be used. Catheter material (latex, silicone) does not influence infection rates
  • 12. For patients with a neurogenic bladder:   Avoid indwelling catheter if possible If assisted bladder drainage is necessary, clean intermittent urinary catheterization should be used.
  • 14. Factors which influence the frequency of surgical wound infection include:       Surgical technique Extent of endogenous contamination of the wound at surgery (eg. Clean, clean – condaminated) Duration of operation Underlying patient status Operating room environment Organism shed by the operating room team
  • 15. A systematic programme for prevention of surgical wound infections includes with the practice of optimal surgical technique and; 1. 2. 3. 4. 5. Operating room environment Operating room staff Pre – intervention preparation of the patient Antimicrobial prophylaxis Surgical wound surveillance
  • 17. Recommended cleaning schedule:  Every morning before any intervention  Between procedures  At the end of the working day  Once a week
  • 18. 2. Operating room staff Handwashing Operating room attire Operating room activity 
  • 19. 3. Pre – intervention preparation of the patient
  • 20. 4. Antimicrobial prophylaxis  Antibiotics must be initiated intravenously within one hour prior to the intervention  In most cases, prophylaxis with a single preoperative dose is sufficient  Administration of prophylactic antibiotics for a longer period prior to the operation is counterproductive, as there will be a risk of infection by a resistant pathogen
  • 21. “ANTIBIOTIC PROPHYLAXIS IS NOT A SUBSTITUTE FOR APPROPRIATE ASEPTIC SURGICAL PRACTICE”
  • 24.  Ventilator-associated pneumonia (VAP), defined as pneumonia occurring >48 - 72 hours after endotracheal intubation, is the most common and fatal nosocomial infection of intensive care.  VAP is associated with increased mortality and morbidity, increased duration of mechanical ventilation, prolonged intensive care unit and hospital stay, and increased cost of hospitalisation.
  • 25. Diagnosis (The Centers for Disease Control Guidelines criteria) Depends on a combination of;  Clinical signs  Impaired gas exchange,  Radiological changes  Positive microscopic analysis
  • 26. Recommendations to prevent these infections include; VAP in the ICUs:     Appropriate disinfection and in-use care of tubing, respirators, and humidifiers to limit contamination No routine changes of respiratory tubing Avoid antacids and H2 blockers Head up position
  • 28. Medical Units Limit medications which impair consciousness  Position comatose patients to limit the potential for aspiration  Avoid oral feeds in patients with swallowing abnormalities  Prevent exposure of neutropenic or transplant patients to fungal spores during construction or renovation 
  • 29. Surgical units  All invasive devices used during anaesthesia must be sterile  Anaesthetist must use gloves and masks when undertaking invasive tracheal or venous or epidural care  Disposable filters (for individual use) for ET intubation effectively prevent the transmission of microorganism among patients by ventilators  Preoperative physiotherapy prevents postoperative pneumonia in patients with chronic respiratory disease.
  • 30. Neurological patients with tracheostomy (with or without ventilation) Sterile suctioning in appropriate frequency  Appropriate cleaning and disinfection of respiratory machines and other devices.  Physiotherapy to assist with drainage of secretions. 
  • 32. Key practices for all vascular catheters includes;  Avoiding catheterization unless there is a medical indication  Maintaining a high level of asepsis for catheter insertion and care  Limiting the use of catheters to as short a duration as possible  Preparing fluids aseptically and immediately before use  Training of personnel in catheter insertion and care
  • 33. Portal of entry for microorganisms in IV System         During manufacture Additives Hairline cracks/ punctures Bottle – tubing junction Medication port Stopcock Insertion site Secondary infection from other side
  • 34. Interventions for – Peripheral vascular catheters  Hands must be washed before all catheters care, using hygienic handwash or rub  Wash and disinfect skin at the insertion site with an antiseptic solution  IV line changes no more frequetly than changes after the transfusion of blood or intralipids, and for discontinuous perfusions  A dressing change is not normally necessary  If local infection or phlebitis occurs, the catheter should be removed immediately
  • 35. Central Vascular catheters  Clean the insertion site with an antiseptic solution  Do not apply solvents or antimicrobial ointment to the insertion site  Mask, cap and sterile gloves and gown must be worn for insertion  The introduction of the catheter and the subsequent catheter dressings require a surgical handwash or rub  Follow appropriate aseptic care in accessing the system, including disinfecting external surfaces of hub and ports
  • 36.  Change of lines should normally not occur more often than once every three days  Change of dressing at the time of the change of lines, following surgical asepsis  Do not replace over a guide wire if infection is suspected  Antimicrobial impregnated catheters may decrease infection in high – risk patients with short – term catheterization
  • 37. Sterile gauze or transparent dressing to cover the catheter site
  • 38. An increase number of catheter lumen may increase the risk of infection
  • 39. Use the subclavion site in preference to jugular or femoral sites
  • 40. Consider using a peripherally inserted central catheter, if appropriate
  • 41. Central vascular totally implanted catheters Implantable vascular access devices should be considered for patients who require long – term therapy.
  • 42. Preventive practices include;  A pre operative shower and implantation under surgical conditions in an operating room  Local preparation includes washing and antisepsis with major antiseptic solution as for other surgical procedures  All PPEs must be worn  Requires strict hand wash prior to procedure  Maintain a closed system during the use of the device.  A change of lines should normally occur every 5 days for continuous use
  • 45. Compliance with handwashing, however, is frequently sub optimal, due to;  Lack of accessible equipment  High staff – to – patient ratios  Allergies to handwashing products  Insufficient knowledge of staff about risks and procedures  Too long a duration recommended for washing
  • 46. Optimal hand hygiene requirements For handwashing; Running water  Products  Facilities for drying 
  • 47. For hand disinfection;  Specific hand disinfectants
  • 48. Procedures Jewellary must be removed before handwashing  Simple hygienic procedures may limited to hands and wrists  Surgical procedures include the hand and forearm 
  • 49. Routine care (minimal) Antiseptic handcleaning (moderate) – aseptic care of infected patients Surgical scrub (surgical care) 1 minute 3-5 minutes With non – antiseptic soap With antiseptic soap With antiseptic soap Quick hygienic hand disinfection (by rubbing) with alcoholic rub. Quick hygienic hand disinfection (by rubbing) with alcoholic rub. Simple handwash and drying followed by two applications of hand disinfectant, then rub to dry
  • 50. 5 MOMENTS OF HANDWASHING…