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General Facts: 
A.First line of defense 
B.Vital to homeostasis 
C.Largest body organ
Functions of the skin: 
1. Protection 
2. Regulate body temperature 
3. Decrease water loss 
4. Contains sensory receptors 
5. Synthesize biochemicals 
6. Excrete waste
Regions 
Epidermis – 
outermost layer 
Dermis – middle 
layer 
Subcutaneous– 
deepest layer
Epidermis 
• Composed of cells in four or five layers 
• Lacks blood vessels 
• Outer portion of the skin that is exposed to 
the external environment and functions in 
protection
Cells of the Epidermis 
• Most cells in the epidermis produce the 
fibrous protein keratin 
• Some cells produce the brown pigment 
melanin 
• Some cells turn on the immune system 
• Some cells function as touch receptors in 
association with sensory nerve endings
Skin Color 
Three pigments contribute to skin color 
•Melanin – yellow to reddish-brown 
to black pigment, responsible for 
dark skin colors 
•Carotene – yellow to orange pigment, 
most obvious in the palms and soles 
of the feet 
•Hemoglobin – reddish pigment 
responsible for the pinkish hue of the 
skin 
Sunlight causes the melanin production to increase. 
Circulation with dermal blood vessels affects skin color.
Dermis 
• Second major skin region 
containing strong, flexible 
connective tissue 
(collagen fibers) and 
blood vessels that carry 
nutrients to upper layers 
of skin and help regulate 
body temperature
Also consists of 
nerves, hair 
follicles, sweat 
glands, oil glands 
and muscles.
Subcutaneous (Hypodermis) 
• Deepest layer of the skin 
• Composed of a fatty layer and loose 
connective tissue 
• It binds the skin to underlying organs and 
contains the blood vessels that supply the 
skin. 
• There is no sharp boundary between the 
dermis and the hypodermis
Skin - Biology

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Skin - Biology

  • 1.
  • 2. General Facts: A.First line of defense B.Vital to homeostasis C.Largest body organ
  • 3. Functions of the skin: 1. Protection 2. Regulate body temperature 3. Decrease water loss 4. Contains sensory receptors 5. Synthesize biochemicals 6. Excrete waste
  • 4. Regions Epidermis – outermost layer Dermis – middle layer Subcutaneous– deepest layer
  • 5. Epidermis • Composed of cells in four or five layers • Lacks blood vessels • Outer portion of the skin that is exposed to the external environment and functions in protection
  • 6.
  • 7. Cells of the Epidermis • Most cells in the epidermis produce the fibrous protein keratin • Some cells produce the brown pigment melanin • Some cells turn on the immune system • Some cells function as touch receptors in association with sensory nerve endings
  • 8. Skin Color Three pigments contribute to skin color •Melanin – yellow to reddish-brown to black pigment, responsible for dark skin colors •Carotene – yellow to orange pigment, most obvious in the palms and soles of the feet •Hemoglobin – reddish pigment responsible for the pinkish hue of the skin Sunlight causes the melanin production to increase. Circulation with dermal blood vessels affects skin color.
  • 9. Dermis • Second major skin region containing strong, flexible connective tissue (collagen fibers) and blood vessels that carry nutrients to upper layers of skin and help regulate body temperature
  • 10. Also consists of nerves, hair follicles, sweat glands, oil glands and muscles.
  • 11. Subcutaneous (Hypodermis) • Deepest layer of the skin • Composed of a fatty layer and loose connective tissue • It binds the skin to underlying organs and contains the blood vessels that supply the skin. • There is no sharp boundary between the dermis and the hypodermis