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Cost of intramuscular versus oral vitamin B12 in Primary Care Josep Vidal-Alaball, Christopher C Butler and Christopher Potter  Department of General Practice / Department of Epidemiology, Statistics and Public Health, University of Wales College of Medicine, Cardiff ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Preliminary results Cost of resources used in parenteral treatment compared with oral treatment: References 1. van Walraven C, Naylor C. Use of vitamin B12 injections among elderly patients by primary care practitioners in Ontario.  Canadian Medical Association Journal  1999;161:146-9. 2. Rickes E, Brink N, Koniuszy F, Wood T, Folkers K. Crystalline vitamin B12.  Science  1948;107:396. 3. Spies T, Stone R, Lopez G, Milanes F, Toca R, Aramburu T. Vitamin B12 by mouth in pernicious and nutritional macrocytic anaemia and sprue.  Lancet  1949;2:454-6. 4. Ross G, Mollin D, Cox E, Ungley C. Hematologic responses and concentration of vitamin B12 in serum and urine following oral administration of vitamin B12 without intrinsic factor.  Blood  1954;9:473-88. 5. Berlin H, Berlin R, Brante G. Oral treatment of pernicious anemia with high doses of vitamin B12 without intrinsic factor.  Acta Medica Scandinavica  1968;184(4):247-58. 6. Berlin R, Berlin H, Brante G, Pilbrant A. Vitamin B12 body stores during oral and parenteral treatment of pernicious anaemia.  Acta Medica Scandinavica  1978;204(1-2):81-4. 7. Norberg B. Oral high-dose cyanocobalamin - a contagious concept.  Rondel , 2001. 8. Lederle FA. Oral cobalamin for pernicious anemia. Medicine's best kept secret?  Journal of the American Medical Association  1991;265(1):94-5. 9. Middleton, J. and Wells, W. Vitamin B12 injections: considerable source of work for the district nurse,  British Medical Journal Clinical Research Ed 1985;  290 :  1254-5.   Effectiveness estimation   We have conducted a systematic review on the use of oral vitamin B 12  for the treatment of vitamin B 12  deficiency. The review concluded that oral vitamin B 12  is a effective as intramuscular vitamin B 12  in treating vitamin B 12  deficiency.  ,[object Object],[object Object],[object Object],SAPC, Glasgow 2004 =

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Cost of intramuscular versus oral vitamin B12 in Primary Care

  • 1.