Progress on the Ondex project in Newcastle in 2009

1. WP3: Telomere uncapping in S. cerevisiae & WP7: Graph analysis Jochen Weile School of Computing Science, Newcastle University

4. New parsers: BioGRID, SBML, SGD

5. The Ondex yeast SB data set

7. Probabilistic and semantic reasoning

9. Develop an easier visualisation method

10. Semantic and probabilistic reasoning for explaining and predicting genetic interactions

11. Achievements of 2009

12. New Ondex meta-data Figure : Ondex meta-graph of merged data from BioGRID, the Jamboree SBML model and the yeast regulatory network (Balaji & Madan-Babu 2004)

13. New Ondex meta-data Figure : Excerpts from the concept class hierarchy, as part of the new meta-data structure

15. Drag 'n drop

16. Undo & redo Video : Ondex meta-data editor

18. Interactions as concepts

19. Automatic determination of participant type Figure : Ondex meta-graph of data from BioGRID.

21. SGD parser

23. The data set SBML SGD Regulatory network BioGRID

24. Visualisation problem interaction, precedence, regulation, [...] ORF name Edge ?

26. Views on Ondex graphs

27. Agenda for 2010

30. BioGRID confidence values from PSI-MIF

31. Dynamic Bayesian network of expression influence

32. Global edge probabilities

33. Reasoning Observation : because: Generalisation : X Y synthetic lethal X Y pre pre pre pre because:

34. Reasoning Patterns Predictions + Suggestions

35. Summary

37. Phillip Lord

39. Eva Holstein

40. Matthew Pocock

41. Darren Wilkinson

42. Simon Cockell

43. Jan Taubert

44. Matthew Hindle

45. Keywan Hassani-Pak

46. Artem Lysenko

47. Catherine Canevet

48. Chris Rawlings Funding :